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| 1 | 早期乳腺癌最佳辅助化疗方案与人类表皮生长因子受体2阳性乳腺癌辅助靶向治疗选择:依据 ASCO 对 CCO临床实践指南的改编显示文摘目的研究加拿大安大略癌症治疗中心(CCO)关于早期乳腺癌最佳辅助化疗方案,包括人类表皮生长因子受体2(HER2)阳性乳腺癌辅助靶向治疗方案,并对其进行改编。方法按照美国临床肿瘤协会(ASCO)对其他组织临床实践指南改编的策略和程序,对CCO临床实践指南的严谨性与内容适用性进行回顾。结果基于对CCO临床实践指南内容的回顾,ASCO小组认为,CCO临床实践指南在整体上清晰全面,以最确切的科学证据为基础,为患者提供可接受的治疗选项。推荐关于辅助化疗方案的决定,应考虑到基线复发风险、毒性、利益可能性和宿主因素(如合并症)。对于高风险HER2阴性的身体状况良好的人群,蒽环类和紫杉烷治疗方案是标准治疗方案。4个周期的多西他赛和环磷酰胺治疗方案是可接受的非蒽环类治疗方案。对于高风险HER2阳性患者,推荐蒽环类与紫杉烷序贯疗法联合曲妥单抗或多西他赛、卡铂、曲妥单抗进行6个周期的治疗。对于低风险、非淋巴结转移、HER2阳性人群,推荐每周一次的紫杉醇和曲妥单抗连续进行12个周期的替代治疗。曲妥单抗应持续使用1年。不应采用铂复合盐对三阴性人群进行常规的辅助管理,除非出现有效的生存数据加以支持。 | Neelima Denduluri Mark R Somerfield Andrea Eisen Jamie N Holloway Arti Hurria Tari A King Gary H Lyman Ann H Partridge Melinda L Telli Maureen E Trudeau Antonio C Wolff 本刊编辑部 | 2016 | 中国全科医学2016，19，18： | 1 |
| 2 | Chemical-kinetic parameters of hyperbolic earth entry显示文摘 | Park C Jaffe R L Partridge H | | 0，，01： | 1 |
| 3 | Potential energy curves and transport properties for the interaction of He with other ground state atoms显示文摘 | Partridge H Stallcop J R Levin E | 2001 | J Chem Phys2001，115，： | 1 |
| 4 | Pairing and phase separation in a polarized fermi gas显示文摘 | Partridge G B LI W H Kamar R I | 2006 | Science2006，311，5760： | 1 |
| 5 | Electroluminescence from polyvinylcarbazole films显示文摘 | Partridge R H | 1983 | Polymer1983，24，6： | 1 |
| 6 | The low-lying states of A1Cu and AIAg显示文摘 | Bausehlicher C W Langhoff Jr S R Partridge H | 1994 | J Chem Phys1994，100，2： | 1 |
| 7 | Electroluminescence from Polyvinylcarbazole Films:Electro luminescence Using Higher Work Functions Cathodes显示文摘 | Partridge R H | 1983 | Polymer1983，24，： | 1 |
| 8 | Transposons Tn1696 and Tn21 and Their Integrons In4 and In2 Have Independent Origins显示文摘 | Partridge S R Brown H J Stokes H W | 2001 | Antimicrob Agents Chemother2001，45，： | 1 |
| 9 | Chemotherapy and targeted therapy for women with human epidermal growth factor receptor 2-negative (or unknown) advanced breast can- cer: American Society of Clinical Oncology Clinical Practice Guideline显示文摘 | Partridge A H Rumble R B Carey L A | 2014 | J Clin Oncol2014，32，29： | 1 |
| 10 | Improved diagnostic accuracy of breast MR1 through combined apparent diffusion coefficients and dynamic contrast enhanced kine-tics显示文摘 | Partridge SC Rahbar H Murthy R | 2011 | Mag netic Resonance in Medicine2011，65，： | 1 |
| 11 | Genome-wide gene expression in response to parasitoid attack in Drosophila 显示文摘 | Wertheim B Kraaijeveld A R Schuster E Blanc E Hopkins M Pletcher S D Strand M R Partridge L Godfray H C | 2005 | Genome Biology2005，6，11： | 1 |
| 12 | Comparison of the binding between ML^+ and ML^2+ ( M = metal,L = noble gas) 显示文摘 | Bauschlicher C W Partridge H Langhoff S R | 1991 | Chem Phys Lett1991，165，： | 1 |
| 13 | Consumption of amino acids by bovine preimplantation embryos显示文摘 | Partridge R J Leese H J | 1996 | Reprod Fertil1996，，8： | 1 |
| 14 | Far-red sensitivity of dragon fish 显示文摘 | PARTRIDGE J C DOUGLAS R H | 1995 | Nature1995，375，： | 1 |
| 15 | On the visual pigments of deep-sea fish 显示文摘 | DOUGLAS R H PARTRIDGE J C | 1997 | J Fish Biol1997，50，： | 1 |
| 16 | Drag- on fish see using chlorophyll 显示文摘 | DOUGLAS R H PARTRIDGE J C DULAI K | 1998 | Nature1998，393，： | 1 |
| 17 | American Society of Clinical Oncology recommendations on fertility presser- vation in cancer patients 显示文摘 | LEE S J SCHOVER L R PARTRIDGE A H | 2006 | J Clin Oncol2006，24，： | 1 |
| 18 | Chemical-kinetic parameters of hyperbolic earth entry显示文摘 | PARK C JAFFE R L PARTRIDGE H | 2001 | Journal of Thermodynamics and Heat Transfer2001，15，1： | 1 |
| 19 | American Society of Clinical Oncology recommendations on fertility preservation in cancer patients 显示文摘 | Lee Stephanie J Schover Leslie R Partridge Ann H | 2006 | Clin Oncol2006，24，18： | 1 |
| 20 | American Society of Clinical Oncology recommendations on fertility preservation in cancer patients 显示文摘 | Lee S J Schover L R Partridge A H | 2006 | J Clin Oncol2006，24，： | 1 |
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