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| 1 | Characterization of hepatic progenitors from human fetal liver using CD34 as a hepatic progenitor marker显示文摘AIM: To enrich putative hepatic progenitors from the developing human fetal liver using CD34 as a marker. METHODS: Aborted fetuses of 13-20 wk were used for the isolation of liver cells. The cells were labeled with anti CD34; a marker used for isolating progenitor population and the cells were sorted using magnetic cell sorting. The positive fractions of cells were assessed for specific hepatic markers. Further, these cells were cultured in vitro for long term investigation. RESULTS: Flow cytometric and immunocytochemical analysis for alphafetoprotein (AFP) showed that the majority of the enriched CD34 positive cells were positive for AFP. Furthermore, these enriched cells proliferated in the long term and maintained hepatic characteristics in in vitro culture. CONCLUSION: The study shows that aborted human fetal liver is a potential source for isolation of hepatic progenitors for clinical applications. The study also demonstrates that CD34 can be a good marker for the enrichment of progenitor populations. | Parveen Nyamath Ayesha Alvi Aejaz Habeeb Sanjeev Khosla Aleem A Khan CM Habibullah | 2007 | World Journal of Gastroenterology2007，13，16： | 9 |
| 2 | A selective approach to the surgical management of periampullary cancer patients and its outcome显示文摘BACKGROUND: Pancreaticoduodenectomy is a high risk, complex, technically challenging operation associated with significant perioperative morbidity and mortality. This study on the surgical management of periampullary cancer patients is based on our experience in a period of nearly 13 years.METHODS: The study was conducted on two groups of patients: group A included 42 patients who were treated between January 2000 and September 2005 and group B included 134 patients who were treated between October 2005 to October 2012. Preoperative, intraoperative and postoperative details of all these patients were collected, tabulated and analyzed to assess the impact of the selective approach introduced in the department with effect from October 2005.RESULTS: Intraoperative details revealed highly significant differences in the management of the two groups of patients in respect of operative time (250.4 vs 126.6 minutes; P<0.001), operative blood loss (1070.2 vs 414.9 m L; P<0.001) and intraoperative blood transfusion (1.4 vs 0.2 units; P<0.001). Variations between the two groups in the frequency of complications were found to be statistically insignificant. However, the difference between the two groups in the overall morbidity of patients (47.6% vs 26.1%; P=0.009) and the length of their hospital stay (11.8 vs 7.8 days; P<0.001) were significant.CONCLUSION: A selective approach applied to the surgical management of periampullary cancer patients is a step in the right direction. | Omar J Shah Irfan Robbani Parveen Shah Sadaf A Bangri Irfan J Khan Mohammad Y Bhat Manmohan Singh | 2014 | Hepatobiliary & Pancreatic Diseases International2014，13，6： | 3 |
| 3 | Antimicrobial Agents from Selected Medicinal Plants in Libya显示文摘Objective:To test the in vitro antimicrobial efficacy of water and methanol extracts of 23 plan species that are commonly used in Libyan folk medicine.Methods:The antimicrobial activity was determinec using the well-diffusion method.Four test microorganisms were used namely,Escherichia coli,Salmonella species,Staphylococcus aureus and Bacillus subtilis.The minimum inhibitory concentration(MIC) was determined for the high biologically active crude plant extracts.Results:Among 23 medicinal plants used in the study,only 5 methanolic extracts[Rosmarinus offcinalis L,Carduus marianium L.,Lantana camara L.,Rhus tripartite(ueria) Grande,and Thymus capitatus(L.) Hoffm(link)]showed the highest antimicrobial activity againsl Staphylococcus aureus,Bacillus subtilis and Salmonella species,while 22 methanolic and aqueous extracts showed moderate to weak antimicrobial activity on all tested organisms.However 19 of the extracts showed no activity at all against Gram-ve and Gram +ve microorganisms.MIC was found to be 1.25 mg/mL(Thymus capitatus),3 mg/mL(Rhus tripartite),4 mg/mL(Carduus marianium),5 mg/mL(Rosamarinus officinalis) and5 mg/mL(Lantana camara),respectively.Conclnsions:The present results revealed that,crude methanolic extracts of the investigated Libyan folk medicinal plants exhibited mild to high in vitro antibacterial activities against Gram-positive and Gram-negative microorganisms. | Hasan MH Muhaisen Miftah Mailoud Ab-Mous Fadel A Ddeeb Aboclaid All Rtemi Omer M Taba Mehtab Parveen | 2016 | Chinese Journal of Integrative Medicine2016，22，3： | 2 |
| 4 | Synthesis,bioas- say, crystal structure and ab initio studies of Erlenmeyer azlactones显示文摘 | Parveen M Ali A Ahmed S | 2013 | Spectrochimica Acta Part a-Molecular and Biomolecular Spectroscopy2013，104，： | 1 |
| 5 | Peritoneal transplantation of human fetal hepatocytes for the treatment of acute fatty liver of pregnancy: a case report 显示文摘 | Khan AA Habeeb A Parveen N | 2004 | Trop Gastreenterol2004，25，3： | 1 |
| 6 | Evaluation of estrogenic activity of phthalate esters by gene expression profiling using a focused microarray (estrarray )显示文摘 | PARVEEN M INOUE A ISE R | 2008 | Environmental Toxicology and Chemistry2008，27，6： | 1 |
| 7 | Safety and efficacy of autologous bone marrow stem cell transplantation through hepatic artery for the treatment of chronic liver failure:a preliminary study显示文摘 | KHAN A A PARVEEN N MAHABOOB V S | 2008 | Transplantat Proc2008，40，4： | 1 |
| 8 | Development and validation of a predictive model for the growth of Vibrio parahaemolyticus in post-harvest shellstock oysters显示文摘 | PARVEEN S DASILVA L DEPAOLA A | 2013 | International Journal of Food Microbiology2013，161，： | 1 |
| 9 | Peritoneal transplantation of human fetal hepatocytes for the treatment of acute fatty liver of preg- nancy: a case report显示文摘 | Khan AA Habeeb A Parveen N | 2004 | Trop Gastroenterol2004，25，3： | 1 |
| 10 | Influence of Different Ureas on Aggregational Properties of Aqueous Surfactant Systems 显示文摘 | Kumar S Khan Z A Parveen N | 2005 | Colloids and Surfaces A: Physicochemical and Engineering Aspects2005，268，13： | 1 |
| 11 | Alkaloids from Veratrum album显示文摘 | RAHMAN A T ALI R T PARVEEN T | 1991 | Ph ytochemistry1991，30，1： | 1 |
| 12 | Genetic diversity of noroviruse and sapovimses in children with acute aporadic gastmen- teritis in New Delhi, India 显示文摘 | Rachakonda G Choudekar A Parveen S | 2008 | J Clin Virol2008，43，1： | 1 |
| 13 | Effects of sweetpotato flour on quality of cookies 显示文摘 | Saeed S Ahmad M M Kausar H Parveen S Masih S Salam A | 2012 | Journal of Agricultural Research2012，50，4： | 1 |
| 14 | Seasonal distribution of total and pathogenic Vibrio parahaemolyticus in Chesapeake Bay oysters and waters 显示文摘 | Parveen S Hettiarachchi K A Bowers J C | 2008 | International Journal of Food Microbiology2008，128，： | 1 |
| 15 | Seasonal distribution of total and pathogenic Vibrio parahaemolyticus in Chesapeake Bay oysters and waters 显示文摘 | Parveen S Hettiarachchi KA Bowers JC Jones JL Tamplin ML McKay R Beatty W Brohawn K Dasilva LV Depaola A | 2008 | Int J Food Microbiol2008，128，2： | 1 |
| 16 | Protective effect of selenomethionine on aflatoxin B1-induced oxidative stress in MDCK cells显示文摘 | PARVEEN F NIZAMANI Z A GAN F | 2014 | Biological Trace Element Research2014，157，3： | 1 |
| 17 | Cdc42: Role in cancer manage- ment显示文摘 | Qadir MI Parveen A Ali M | 2015 | Chem Biol Drug Des2015，86，4： | 1 |
| 18 | Acetylcholinester-ase inhibiting triterpenoidal alkaloids from Buxus hyrcana显示文摘 | ATTA-UR-RAHMAN PARVEEN S KHALID A | 1998 | Heterocy-cles1998，49，1： | 1 |
| 19 | An insertion in loop L7 of human eosinophil - derived neurotoxin is crucial for its antiviral activity 显示文摘 | Sikriwal D Seth D Parveen S Malik A | 2012 | Journal of Cellular Biochemistry2012，113，10： | 1 |
| 20 | Development and validation of a predictive model for the growth of Vibrio parahaemolyticus in post-harvest shellstock oysters 显示文摘 | Parveen S DaSilva L DePaola A | 2013 | International Journal of Food Microbiology2013，161，： | 1 |
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