|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | BMC Medicine论文摘要汇编——风险预测模型评估的不确定性对治疗决策影响的队列研究:以英国基层医疗机构心血管病患者为例显示文摘背景风险预测模型通常在临床中用于辅助决策。但是,目前很少有研究对于风险预测模型评估超出可信区间(CI)的风险评分的不确定性进行探讨。本文旨在对采用基于QRISK预测工具建立的不同风险预测模型评估的患者发病风险的不确定性进行分析。方法从英国临床研究数据库选取3 792 474例具有住院治疗数据及死亡记录、符合研究要求并可以进行心血管病(CVD)风险评估的患者。采用建立QRISK 2和QRISK 3模型的方法建立风险预测模型(模型A^F),然后校正可能导致各模型预测能力差异的因素以及填补缺失数据后再进行预测。比较各模型的十年风险评分以及一般性能。结果不同模型评估患者CVD风险结果有显著差异。模型A评估男性CVD风险95%CI为(4.4%,16.3%)、女性为(4.6%,15.8%),模型F评估患者CVD风险95%CI为(9%,10%)。一般性能指标评价各模型预测能力相似(Harrell’s C=0.86~0.87)。造成各模型风险预测能力差异最大的因素为CVD发病长期趋势,校正此因素后,女性发病风险预测HR差异可降低0.96(0.95,0.96),男性可降低0.96(0.96,0.96)。当使用模型对英国人群进行风险评估时,有380万人可能被重新归类到符合使用他汀类药物的患者人群。本研究的一个重要局限性是没有纳入CPRD数据库中缺失的可能因素,如饮食或体育活动等。结论基于日常资料对患者CVD发病风险的预测结果因模型而异。尽管各模型预测结果可存在很大的差异,但普通性能指标评价各模型的预测能力相似。在做临床决策时,还应考虑临床评估结果和其他风险因素。对CVD发病长期趋势因素,应做进一步研究。 | 本刊编辑部(整理) PATE A EMSLEY R ASHCROFT D M | 2019 | 中国全科医学2019，22，29： | 2 |
| 2 | A generalized performance prediction method for adiabatic capillary tubes 显示文摘 | Bittle R R Wolf D A Pate M B | 1998 | Int J of HVAC&R Research1998，4，1： | 1 |
| 3 | Adiabatic capillary tube performance with alternative refrigerants 显示文摘 | Wolf D A Bittle R R Pate M B | 1995 | ASHRAE Transactions1995，101，： | 1 |
| 4 | Percutaneous clo- sure of prosthetic paravalvular leaks : Case series and review 显示文摘 | Pate GE A1 Zubaidi A Chandavimol M | 2006 | Catheter Cardiovasc Interv2006，68，4： | 1 |
| 5 | Assessing children's physical activity in their homes:the observational system for recording physical activity in children-home显示文摘 | Mciver K L Brown W H Pfeiffer K A Dowda M Pate R R | 2009 | Journal of applied behavior analysis2009，42，1： | 1 |
| 6 | Vibration of clamped plate with concentrated mass and spring attachments显示文摘 | Ingber M S Pate A L Salazar J M | 1992 | Journal of Sound and Vibration1992，153，1： | 1 |
| 7 | In Vivo Lipopolysaccharide exposure of human blood leukocytes induces cross-tolerance to multiple TLR ligands显示文摘 | De Vos A F Pate Van Den Pangaart P S et 01 | 2009 | J Immunol2009，183，1： | 1 |
| 8 | Seasonal water acquisition and redistribution in the Australian woody phreatophyte, Banksia prionotes显示文摘 | Burgess S O Pate J S Adams M A | 2000 | Annals Botany2000，85，： | 1 |
| 9 | Technology innovation-in- duced business model change: acontingency approach显示文摘 | PATELI A G GIAGLIS G M | 2005 | Organizational Change Management2005，18，2： | 1 |
| 10 | Global trends in emerging infectious diseases显示文摘 | Jones K E Pate I N G Levy M A | 2008 | Nature2008，451，： | 1 |
| 11 | Pliocene stable isotope stratigraphy of ODP site 846 显示文摘 | Shacklelon N J Hall M A Pate D | 1995 | Proceedings of the ocean Drilling Program Scientific Results1995，138，： | 1 |
| 12 | Validity of field tests of upper body muscular strength显示文摘 | PATE R R BURGESS M L WOODS J A | 1993 | Res Q Exe Sport1993，64，： | 1 |
| 13 | Heat transfer and pressure drop during evaporation and condensation of R22 in horizontal micro-fin tubes显示文摘 | L M Schlager M B Pate A E Bergles | 1989 | International Journal of Refrigeration1989，12，1： | 1 |
| 14 | Technology innovation-induced business model change: a contingency approach显示文摘 | PATELI A G GIAGLIS G M | 2005 | Journal of Organizational Change Management2005，18，2： | 1 |
| 15 | Multiple independent emer- gences of type 2 vaccine-derived polioviruses during a large outbreak in northern Nigeria显示文摘 | Burns C C Shaw J Jorba J Bukbuk D Adu F Gumede N Pate M A Abanida E A Gasasira A Iber J Chen Q Vincent A Chenoweth P Henderson E Wannemuehler K Naeem A Umarni R N Nishimura Y Shimizu H Baba M Adeniji A Williams A J Kil- patrick D R Oberste M S Wassilak S G Tomori O Pallansch M A Kew O | 2013 | J Virol2013，87，9： | 1 |
| 16 | Wireless value-added services in exhibition shows显示文摘 | Pateli A G Giaglis G M Spinellis D D | 2006 | Int J Mobile Communica- tions2006，4，2： | 1 |
| 17 | Percutaneous closure of prosthetic paravalvular leaks = case series and review显示文摘 | Pate GE A1 Zubaidi A Chandavimol M | 2006 | Catheter Cardiovasc lnterv2006，68，4： | 1 |
| 18 | Heat transfer and pressure drop during evaporation and condensation of R22 in horizontal micro-fin tubes显示文摘 | Schlager L M Pate M B Bergles A E | | 0，，01： | 1 |
| 19 | Racial Ddifferences in Self-reported Healthcare Seeking and Treatment for Urinary Incontinence in Community-dwelling Women from the EPI Study显示文摘 | Berger M B Pate] D A Miller J M | 2011 | Neurourology and Urodynamics2011，30，8： | 1 |
| 20 | Synthesis and characterization of nanosilica prepared by precipition method显示文摘 | Jal P K Sudarshan M Ssha A Sabita Pate/ | 2004 | Colloids and Surfaces A: Physicochemical and Engineering Aspects2004，240，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员