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| 1 | 直接评估吗啡刺激糖尿病人隐静脉内皮一氧化氮释放减少显示文摘to directly measure in real time basal and stimulated levels of NO released from human saphenous vein endothelium and to quantify the expression of the μopiate receptor, which has been linked with NO release. METHODS: Saphenous vein segments from patients with type 2 diabetes ( n = 12) and patients without diabetes (n =8) were obtained. The release of NO was measured directly from the endothelium using a NO-specific amperometric probe. NΩ-nitro-L-arginine methyl ester (L-NAME, 0.1 mmol/L), a NO synthase (NOS) inhibitor, or morphine (1 μmol/L), a stimulant, was administered and the measurements were repeated. Values were reported relative to the mean initial measurement of NO release from diabetic endothelium, which was defined as the relative zero level of NO release. A RT-PCR was then performed on the endothelium to measureμ opiate receptor expression. RESULTS: Diabetic patients (n = 12) showed a relative and significantly diminished basal level of released NO, (0.049± 0.012) nmol/L, compared | Thomas V BILHNGER, James A VOSSWINKEL, Patrick CADET, Christos M RIALAS, Harold I MAGAZINE, George B STEFANO(Division of Cardiothoracic Surgery, Department of Surgery, University Hospital and Medical Center, HSC, T19-080, Stony Brook, New York 11794-8191 Neuroscience Research Institute, State University of New York College at Old Westbury, Old Westbury, New York , USA) | 2002 | Acta Pharmacologica Sinica2002，23，2： | 3 |
| 2 | Coping with Non-purchase: Managing the Stress of Inaction Regret 显示文摘 | Patrick V M Lancellotti M P Demello G | 2009 | Journal of Consumer Psychology2009，19，3： | 1 |
| 3 | The posterolateral approach for the treatment of trimalleolar fractures 显示文摘 | Naeder H Dominik M Patrick V | 2007 | Tech Foot Ankle Surg2007，6，1： | 1 |
| 4 | Species substitution for carbon storage: Sessile oak versus Corsican pine in France as a case study显示文摘 | Patrick V Céline M Ingrid S | 2009 | Forest Ecology and Management2009，257，4： | 1 |
| 5 | Coping with Non-purchase: Managing the Stress of Inaction Regret 显示文摘 | Patrick V M LancellottI M P Demello G | 2009 | Journal of Consumer Psychology2009，19，3： | 1 |
| 6 | Coping with Non-purchase: Managing the Stress of Inaction Regret 显示文摘 | Patrick V M Lancellotti M P Demello G | 2009 | Journal of Consumer Psychology2009，19，3： | 1 |
| 7 | A heuristic for solving mixed-model line balancing problems with stochastic task durations and parallel stations显示文摘 | PATRICK R M GREGORY V F | 1997 | International Journal of Production Economics1997，51，3： | 1 |
| 8 | Phosphorylation of NF-r,B and Ird3 proteins: implications in cancer and inflammation 显示文摘 | Patrick V Marie-Paule M Chariot VB | 2005 | Trends Biochem Sci2005，30，1： | 1 |
| 9 | 'I don' t' versus 'I can' t': When empowered refusal motivates goal-directed behavior显示文摘 | Patrick V M and Hagtvedt H | 2012 | Journal of Consumer Research2012，39，2： | 1 |
| 10 | Genetic effects of artificial propagation: signal from wild and hatchery populations of red abalone in California显示文摘 | Patrick M Rubin V P Hedgecock D | 1996 | Aquac1996，143，： | 1 |
| 11 | Molecular characterization of resistance plasmids in epidemiologically unrelated strains of multiresistant Haemophilus in fluenzae显示文摘 | Jack L Godelieve V Patrick D M | 1993 | J Infect Dis1993，168，7： | 1 |
| 12 | The clinical relevance of micropapillary carcinoma of the breast: a case-control study显示文摘 | Andrea V Patrick M Patrizia D | 2013 | Histopathology2013，63，2： | 1 |
| 13 | Structure-activity relationships for inhibition of type 1 and 2 human 5α-Reductase显示文摘 | Curt D H Patrick R M | 1994 | J Med Chem1994，37，15： | 1 |
| 14 | High-temperature sulfidafion-regeneration of CuO-A12 03 sorbents 显示文摘 | PATRICK V GAVALAS G R FLYTZANI-STEPHANOPO- ULOS M | 1989 | Industrial & Engineering Chemistry Research1989，28，7： | 1 |
| 15 | Surgical options in ICHincluding decompressive craniotomy 显示文摘 | Patrick M Barbara A G Raghu R V | 2007 | Neurological Sciences2007，261，12： | 1 |
| 16 | 2, 2, 2- Trichloro-N- ( { 2- - 1, 3- dioxo-2, 3-dihydro-lH-benzo iso-quinolin-5-yl } carbamoyl) acetamide ( UNBS3157 ), a novel nonhematotoxic naphthalimide derivative with potent antitumor activity 显示文摘 | Eric V Q Tine M Patrick D | 2007 | Journal of Medicinal Chemistry2007，50，17： | 1 |
| 17 | Probabilistic environmental risk assessment of zinc in Dutch surface water显示文摘 | Patrick A V Frederik A M Peter A V | 2004 | Environmental Toxicology and Chemistry2004，23，29： | 1 |
| 18 | Paying before consuming: Examining the robustness of consumers' preference for prepayment 显示文摘 | Patrick V M Park C W | 2006 | Journal of Retailing2006，82，3： | 1 |
| 19 | Human Paragonimiasis After Eating Raw or Undercooked Crayfish - Missouri, July 2006-September 2010显示文摘 | Patrick S L Turabelidze G Marx H Grim A Lane M A Weil G J Bailey T C ?nen N F Demertzis L M Tuteur P G Hayes E V Davila S Z Folk S M Mitchem R E Kammerer E Fannon L P Jones J L Wilkins P P Lo Y C | 2010 | MMWR. Morbidity and Mortality Weekly Report2010，，： | 1 |
| 20 | Downregulation of XPF-ERCC1 enhances cispla- tin efficacy in cancer cells显示文摘 | Arora S Kothandapani A Tillison K Kalman-Maltese V Patrick S M | 2010 | DNA Repair (Amst)2010，9，7： | 1 |
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