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24篇 您的检索式:作者名="Perissi"
    题名 作者 年代 出处 被引量
1Ionic liquids as diather- mic fluids for solar trough collectors' technology: A corro- sion study显示文摘Perissi I Bardi U Caporali S etal 2008Solar Energy Materials and Solar Cells2008,92,4:1
2A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors 显示文摘Perissi V Aggarwal A Glass C K 2004Cell2004,116,:1
3Aluminium electroplated from ionic liquids as protective coating against steel corrosion显示文摘Stefano Caporali Alessio Fossati Alessandro Lavacchi Ilaria Perissi Alexander Tolstogouzov Ugo Bardi 2007Corrosion Science2007,,2:1
4Aluminium electroplated from ionic liquids as protective coating against steel corrosion显示文摘CAPORALI S FOSSATI A LAVACCHI A PERISSI I TOLSTOGOUZOV A BARDI U 2008Corrosion Science2008,50,2:1
5High temperature corrosion properties of ionic liquids显示文摘Perissi I Bardi U Caporali S 2006Corrosion Science2006,6,:1
6A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors显示文摘Perissi V Aggarwal A Glass CK 2004Cell2004,116,4:1
7Molecular determinants of nuclear receptor-corepressor interaction显示文摘Perissi V Staszewski LM McInerney EM 1999Genes Dev1999,13,24:1
8AP-2 Transcription Factors in the Regulation of ERBB2 Gene Transcription by Oestrogen 显示文摘PERISSI V MENINI N COTTONE E 2000Oncogene2000,19,2:1
9Tissue- specific regulation of retinal and pituitary precursor cell proliferation显示文摘Li X Perissi V Liu F 2002Science2002,297,5584:1
10Aluminum eleetroplated from ionic liquids as protective coating against steel corrosion 显示文摘Caporali S Fossati A Lavacchi A Perissi I Tolstogouzov A Bardi U 2008Corrosion Science2008,50,:1
11High temperature corrosion prop-erties of ionic liquids显示文摘Perissi I Bardi U Caporali S 0,,:1
12Tissue-specific regulation of retinal and pituitary precursor cell proliferation显示文摘Li X Perissi V Liu F 2002Science2002,297,5584:1
13Controlling nuclear receptors: the circular logic of eofactor cycles显示文摘PERISSI V ROSEN FELD M G 2005Nat Rev Mol Cell Biol2005,6,7:1
14AP-2 transcription factors in the regulation of ERBB2 gene transcription by oestrogen显示文摘PERISSI V MENINI N COTTINE E 2000Oncogene2000,19,2:1
15A topoisomerase II β- mediated dsDNA break required for regulated transcription显示文摘Ju BG Lunyak VV Perissi V 2006Science2006,312,5781:1
16The histone deacetylase-3 complex contains nuclear receptor corepressors 显示文摘Wen YD Perissi V Staszewski LM 2000Proc Natl Acad Sci U S A2000,97,13:1
17Electrodeposition of aluminium film on P90 Li–Al alloy as protective coating against corrosion显示文摘U. Bardi S. Caporali M. Craig A. Giorgetti I. Perissi J.R. Nicholls 2008Surface & Coatings Technology2008,,10:1
18Tissue-specific regulation of ret- inal and pituitary precursor cell proliferation显示文摘Li X Perissi V Liu F 2002Science2002,297,5584:1
19Controlling nuclear receptors:The circularlogic of cofactor cycles显示文摘Perissi V Rosenfeld MG 2005Nat Rev Mol Cell Biol2005,6,7:1
20Multiplex gene expression profile in inflamed mucosa of patients with Crohn’s disease ileal localization: A pilot study显示文摘BACKGROUND Crohn’s disease (CD) is a complex disorder resulting from the interaction of genetic,environmental,and microbial factors.The pathogenic process may potentially affect any segment of the gastrointestinal tract,but a selective location in the terminal ileum was reported in 50% of patients.AIM To characterize clinical sub-phenotypes (colonic and/or ileal) within the same disease,in order to identify new therapeutic targets.METHODS 14 consecutive patients undergoing surgery for ileal CD were recruited for this study.Peripheral blood samples from each patient were collected and the main polymorphisms of the gene Card15/Nod2 (R702W,G908R,and 1007fs) were analyzed in each sample.In addition,tissue samples were taken from both the tract affected by CD and from the apparently healthy and disease-free margins (internal controls).We used a multiplex gene assay in specimens obtained from patients with ileal localization of CD to evaluate the simultaneous expression of 24 genes involved in the pathogenesis of the disease.We also processed surgery gut samples with routine light microscopy (LM) and transmission electron microscopy (TEM) techniques to evaluate their structural and ultrastructural features.RESULTS We found a significant increase of Th17 (IL17A and IL17F,IL 23R and CCR6) and Th1 (IFN-γ) gene expression in inflamed mucosa compared to non-inflamed sites of 14 CD patients.DEFB4 and HAMP,two genes coding for antimicrobial peptides,were also strongly activated in inflamed ileal mucosa,suggesting the overwhelming stimulation of epithelial cells by commensal microbiota.IFN-γ and CCR6 were more expressed in inflamed mucosa of CD patients with ileal localization compared with patients with colonic localization suggesting a more aggressive inflammation process in this site.Morphological analysis of the epithelial lining of Lieberkün crypts disclosed enhanced release activity from goblet mucocytes,whereas the lamina propria contained numerous cells pertaining to various lines.CONCLUSION We observed that the expression of ileal genes related to Th1 and Th17 activity is strongly activated as well as the expression of genes involved in microbiota regulation.Francesco Giudici Letizia Lombardelli Edda Russo Tiziana Cavalli Daniela Zambonin Federica Logiodice Ornela Kullolli Lamberto Giusti Tatiana Bargellini Marilena Fazi Livia Biancone Stefano Scaringi Ann Maria Clemente Eloisa Perissi Giovanni Delfino Maria G Torcia Ferdinando Ficari Francesco Tonelli Marie-Pierre Piccinni Cecilia Malentacchi 2019World Journal of Clinical Cases2019,7,17:1
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