| 1 | Helping the Consumers and Producers of Standards,Repositories and Policies to Enable FAIR Data显示文摘Thousands of community-developed(meta)data guidelines,models,ontologies,schemas and formats have been created and implemented by several thousand data repositories and knowledge-bases,across all disciplines.These resources are necessary to meet government,funder and publisher expectations of greater transparency and access to and preservation of data related to research publications.This obligates researchers to ensure their data is FAIR,share their data using the appropriate standards,store their data in sustainable and community-adopted repositories,and to conform to funder and publisher data policies.FAIR data sharing also plays a key role in enabling researchers to evaluate,re-analyse and reproduce each other’s work.We can map the landscape of relationships between community-adopted standards and repositories,and the journal publisher and funder data policies that recommend their use.In this paper,we show how the work of the GO-FAIR FAIR Standards,Repositories and Policies(StRePo)Implementation Network serves as a central integration and cross-fertilisation point for the reuse of FAIR standards,repositories and data policies in general.Pivotal to this effort,the FAIRsharing,an endorsed flagship resource of the Research Data Alliance that maps the landscape of relationships between community-adopted standards and repositories,and the journal publisher and funder data policies that recommend their use.Lastly,we highlight a number of activities around FAIR tools,services and educational efforts to raise awareness and encourage participation. | Peter McQuilton Dominique Batista Oya Beyan Ramon Granell Simon Coles Massimiliano Izzo Allyson L.Lister Robert Pergl Philippe Rocca-Serra Ben Schaap Hugh Shanahan Milo Thurston Susanna-Assunta Sansone | 2020 | Data Intelligence2020，2，1： | 5 |
| 5 | The evolution of pyrrolizidine alkaloid diversity among and within Jacobaea species显示文摘Plants produce many secondary metabolites showing considerable inter-and intraspecific diversity of concentration and composition as a strategy to cope with environmental stresses.The evolution of plant defenses against herbivores and pathogens can be unraveled by understanding the mechanisms underlying chemical diversity.Pyrrolizidine alkaloids are a class of secondary metabolites with high diversity.We performed a qualitative and quantitative analysis of 80 pyrrolizidine alkaloids with liquid chromatography-tandem mass spectrometry of leaves from 17 Jacobaea species including one to three populations per species with 4–10 individuals per population grown under controlled conditions in a climate chamber.We observed large inter-and intraspecific variation in pyrrolizidine alkaloid concentration and composition,which were both species-specific.Furthermore,we sequenced 11 plastid and three nuclear regions to reconstruct the phylogeny of the 17 Jacobaea species.Ancestral state reconstruction at the species level showed mainly random distributions of individual pyrrolizidine alkaloids.We found little evidence for phylogenetic signals,as nine out of 80 pyrrolizidine alkaloids showed a significant phylogenetic signal for Pagel'sλstatistics only,whereas no significance was detected for Blomberg's K measure.We speculate that this high pyrrolizidine alkaloid diversity is the result of the upregulation and downregulation of specific pyrrolizidine alkaloids depending on ecological needs rather than gains and losses of particular pyrrolizidine alkaloid biosynthesis genes during evolution. | Yangan Chen Patrick P.J.Mulder Onno Schaap Johan Memelink Peter G.L.Klinkhamer Klaas Vrieling | 2022 | Journal of Systematics and Evolution2022，60，2： | 0 |
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