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| 1 | Long-term propagation of tree shrew spermatogonial stem cells in culture and successful generation of transgenic offspring显示文摘树鼯有一种靠近的关系到首领并且在生物医学的研究比啮齿类动物有许多优点。然而,基因操作方法的缺乏妨碍了这个动物的更宽的使用。Spermatogonial 干细胞(SSC ) 成功地在文化被扩展了允许复杂基因在老鼠和老鼠编辑。这里,没有干细胞性质的损失,我们为树鼯 SSC 的长期的扩大描述一个文化系统。在我们的学习,胸腺房间抗原 1 被用来充实树鼯 SSC。定序 RNA 分析表明表明小径的 Wnt/-catenin 在无差别的 SSC 是活跃的,但是是在 SSC 区别的开始之上的 downregulated。树鼯的暴露到 recombinant Wnt3a 蛋白质的主要 SSC 在文化的起始的段落期间提高了 SSC 的幸存。当 feeder 被发现为树鼯 SSC 增长必要,树鼯 Sertoli 房间,然而并非老鼠使用胚胎的成纤维细胞,导致柔韧的房间扩大和长期的文化。扩展的树鼯 SSC 是有提高的绿色的 transfected 荧光灯表示 lentiviral 向量的蛋白质(EGFP ) 。在进消毒的成年的男树鼯睾丸的移植以后,标注 EGFP 的 SSC 能恢复精子发生并且成功地产生转基因的后代。而且,这些 SSC 对 CRISPR/Cas9-mediated 基因修正合适。在有编辑的基因的联合的树鼯 SSC 接近膨胀的一个文化系统的发展用树鼯为精确染色体操作铺平道路。 | Chao-Hui Li Lan-Zhen Yan Wen-Zan Ban Qiu TH Yong Wu Lin Wang Rui Bi Shuang Ji Yu-Hua Ma Wen-Hui Nie Long-Bao Lv Yong-Gang Yao Xu-Dong Zhao Ping Zheng | 2017 | Cell Research2017，27，2： | 22 |
| 2 | Association between Vitamin D Insufficiency and the Risk for Gestational Diabetes Mellitus in Pregnant Chinese Women显示文摘Objective To investigate the association between vitamin D deficiency and risk of gestational diabetes mellitus(GDM) in pregnant Chinese women.Methods A nested case-control study was conducted.Clinical and biochemical data were analyzed for 200 subjects with GDM and 200 subjects with normal glucose tolerance(NGT).Results The median(interquartile range) serum 25-hydroxyvitamin D(25OHD) levels were 22.39(17.67,29.38) and 25.86(19.09,34.88) nmol/L in the GDM and NGT groups,respectively.Rates of 25OHD deficiency or insufficiency were significantly higher in the GDM group than in the NGT group.Subjects with 25OHD levels <25 nmol/L had a 1.8-fold higher risk of GDM compared with subjects with higher vitamin D levels.In the GDM group,serum 25OHD was independently associated with HbA1c and insulin resistance after adjusting for confounding factors.In the NGT group,serum 25OHD was independently associated with fasting plasma glucose and systolic blood pressure after adjusting for maternal age and other confounding factors.Conclusion 25OHD insufficiency is very common in Chinese women.Low 25OHD status may be associated with insulin resistance and act as a risk factor for GDM. | WANG Ou NIE Min HU Ying Ying ZHANG Kui LI Wei PING Fan LIU Jun Tao CHEN Li Meng XING Xiao Ping | 2012 | Biomedical and Environmental Sciences2012，25，4： | 21 |
| 3 | Phosphorus recovery from biogas fermentation liquid by Ca-Mg loaded biochar显示文摘Shortage in phosphorus(P) resources and P wastewater pollution is considered as a serious problem worldwide. The application of modified biochar for P recovery from wastewater and reuse of recovered P as agricultural fertilizer is a preferred process. This work aims to develop a calcium and magnesium loaded biochar(Ca–Mg/biochar) application for P recovery from biogas fermentation liquid. The physico-chemical characterization, adsorption efficiency, adsorption selectivity, and postsorption availability of Ca-Mg/biochar were investigated. The synthesized Ca–Mg/biochar was rich in organic functional groups and in Ca O and Mg O nanoparticles. With the increase in synthesis temperature, the yield decreased, C content increased, H content decreased, N content remained the same basically, and BET surface area increased. The P adsorption of Ca–Mg/biochar could be accelerated by nano-Ca O and nano-Mg O particles and reached equilibrium after 360 min.The process was endothermic, spontaneous, and showed an increase in the disorder of the solid–liquid interface. Moreover, it could be fitted by the Freundlich model. The maximum P adsorption amounts were 294.22, 315.33, and 326.63 mg/g. The P adsorption selectivity of Ca–Mg/biochar could not be significantly influenced by the typical p H level of biogas fermentation liquid. The nano-Ca O and nano-Mg O particles of Ca–Mg/biochar could reduce the negative interaction effects of coexisting ions. The P releasing amounts of postsorption Ca–Mg/biochar were in the order of Ca–Mg/B600 > Ca–Mg/B450 > Ca–Mg/B300. Results revealed that postsorption Ca–Mg/biochar can continually release P and is more suitable for an acid environment. | Ci Fang Tao Zhang Ping Li Rongfeng Jiang Shubiao Wu Haiyu Nie Yingcai Wang | 2015 | Journal of Environmental Sciences2015，27，3： | 21 |
| 4 | Antigen-presenting effects of effector memory Vγ9Vδ2 T cells in rheumatoid arthritis显示文摘 | Chaoying Hu Liu Qian Yi Miao Qiuyu Huang Ping Miao Ping Wang Qiwen Yu Hong Nie Jiying Zhang Dongyi He Rong Xu Xuehua Chen Bingya Liu Dongqing Zhang | 2012 | Cellular & Molecular Immunology2012，9，3： | 18 |
| 5 | Expression and Comparative Analysis of Genes Encoding Outer Membrane Proteins LipL21,LipL32 and OmpL1 in Epidemic Leptospires显示文摘Leptospiral 外部膜蛋白质(OMP ) 高度在不同种类被保存,并且在新免疫保护和 serodiagnosis 策略的发展起一个必要作用。编码 LipL21, LipL32 和 OmpL1 的基因从螺旋体 interrogans serovar lai 种类 Lai 的完全的染色体顺序被克隆并且表示了试管内。顺序比较分析表明三基因高度在不同流行 leptospires 之中被保存,包括三主要流行种类螺旋体 interrogans,螺旋体 borgpetersenii 和螺旋体 weilii,在中国。Immunoblot 分析进一步被执行用重组体 OMP 的反时代细看 15 个流行螺旋体参考种类。两免疫污点试金和反向的抄写聚合酶链反应证明这三 OMP 保存地在病原的 L 被表示。interrogans 种类和另外的病原的 leptospires。另外,这些重组体 OMP 的使用作为在为细螺旋体病的 serodiagnosis 的连接酶的免疫吸着剂试金(ELISA ) 的抗原被评估。重组体 LipL32 和 OmpL1 蛋白质与重量的单位显示出 ELISA 反应的高度一感染 L 的 from 病人。interrogans 拉紧 Lai 和另外的病原的 leptospires。这些结果可以贡献宽广范围的疫苗和免疫的候选人的鉴定在进一步的研究的诊断抗原。 | Xiang-Yan ZHANG Yang YU Ping HE Yi-Xuan ZHANG Bao-Yu HU Yang YANG Yi-Xin NIE Xiu-Gao JIANG Guo-Ping ZHAO Xiao-Kui GUO | 2005 | Acta Biochimica et Biophysica Sinica2005，37，10： | 12 |
| 6 | Clinical applications of MARSALA for preimplantation genetic diagnosis of spinal muscular atrophy显示文摘Conventional PCR methods combined with linkage analysis based on short tandem repeats(STRs) or Karyomapping with single nucleotide polymorphism(SNP) arrays, have been applied to preimplantation genetic diagnosis(PGD) for spinal muscular atrophy(SMA), an autosome recessive disorder. However, it has limitations in SMA diagnosis by Karyomapping, and these methods are unable to distinguish wildtype embryos with carriers effectively. Mutated allele revealed by sequencing with aneuploidy and linkage analyses(MARSALA) is a new method allowing embryo selection by a one-step next-generation sequencing(NGS) procedure, which has been applied in PGD for both autosome dominant and X-linked diseases in our group previously. In this study, we carried out PGD based on MARSALA for two carrier families with SMA affected children. As a result, one of the couples has given birth to a healthy baby free of mutations in SMA-causing gene. It is the first time that MARSALA was applied to PGD for SMA, and we can distinguish the embryos with heterozygous deletion(carriers) from the wild-type(normal) ones accurately through this NGS-based method. In addition, direct mutation detection allows us to identify the affected embryos(homozygous deletion), which can be regarded as probands for linkage analysis, in case that the affected family member is absent. In the future, the NGS-based MARSALA method is expected to be used in PGD for all monogenetic disorders with known pathogenic gene mutation. | Yixin Ren Xu Zhi Xiaohui Zhu Jin Huang Ying Lian Rong Li Hongyan Jin Yan Zhang Wenxin Zhang Yanli Nie Yuan Wei Zhaohui Liu Donghong Song Ping Liu Jie Qiao Liying Yan | 2016 | Journal of Genetics and Genomics2016，43，9： | 9 |
| 7 | Chaotic characteristics of electromagnetic emission signals during deformation and fracture of coal显示文摘Electromagnetic emission(EME) is a kind of physical phenomenon accompanying the process of deformation and fracture of loaded coal and rock and it is of importance in quantitatively analyzing its characteristics.This will reveal the process of deformation and fracture of coal and predicting dynamic disasters in coal mines.In this study,the G-P(Grassberger and Procaccia) algorithm,calculation steps of the(if only 1 dimension) correlation dimension of time series and the identification standards of chaotic signals are introduced.Furthermore,the correlation dimensions of EME and the acoustic emission(AE) signals of time series during deformation and fracture of coal bodies are calculated and analyzed.The results show that the time series of pulses number of EME and the time series of AE count rate are chaotic and that the saturation embedding dimensions of a K3 coal sample are,respectively,5 and 6.The results can be used to provide basic parameters for predicting of EME and AE time series. | NIE Bai-sheng HE Xue-qiu LIU Fang-bin ZHU Cheng-wei WANG Ping | 2009 | Mining Science and Technology2009，19，2： | 8 |
| 8 | Simultaneous desulfurization and denitrogen of liquid fuels using two functionalized group ionic liquids显示文摘Deep desulfurization of liquid fuels is an important and challenging issue in worldwide petroleum refining industry.Extraction and catalytic oxidative desulfurization(ECODS)of liquid fuels using a series of ionic liquids(ILs)with two functionalized groups,such as[(CH2)2COOHmim]Cl/n Fe Cl3,[(CH2)2COOHmim]Cl/n Zn Cl2,and[Amim]Cl/n Fe Cl3,was studied.In the ECODS,the ILs were used as both extractant and catalyst and 30 wt%hydrogen peroxide(H2O2)solution as oxidant.The effects of molar ratios of[(CH2)2COOHmim]Cl(or[Amim]Cl)to Fe Cl3(or Zn Cl2)in ILs,H2O2/sulfur(O/S)molar ratio,reaction temperature,and the nature of sulfur compounds on sulfur removal were investigated.The natures of the functional groups(–COOH,–CH2–CH=CH2)in cations and the acid strength of anions play important roles in the ECODS and affect the reaction time,temperature,and desulfurization efficiency of different substrates.Also,nitrogen-containing compounds(pyridine,pyrrole,and quinoline)could be removed simultaneously in the ECODS and had different effects on dibenzothiophene removal. | NIE Yi GONG Xue GAO Hong Shuai ZHANG Xiang Ping ZHANG Suo Jiang | 2014 | Science China Chemistry2014，57，12： | 8 |
| 9 | MiR-21/RASA1 axis affects malignancy of colon cancer cells via RAS pathways显示文摘AIM:To determine how the oncogene mi R-21 regulates the RAS signaling pathways and affects colon cancer cell behaviors.METHODS:RAS p21 GTPase activating protein 1(RASA1) protein expression in six colon cancer cell lines was assessed by Western blot.Colon cancer RKO cells were chosen for transfection because they are KRAS wild type colon cancer cells whose RASA1 expression is significantly decreased.RKO cells were transfected with vectors overexpressing or downregulating either mi R-21 or RASA1.Furthermore,a luciferase reporter assay was used to determine whether RASA1 is a gene target of mi R-21.Then,changes in m RNA and protein levels of RASA1,RASGTP,and other components of the RAS signaling pathways were assessed in transfected RKO cells by real-time quantitative reverse transcription-polymerase chain reaction,Western blot and immunoprecipitation.Finally,cell proliferation,apoptosis,invasion,and tumorformation ability w ere assessed by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide dye assay,flow cytometry,transwell assay,and animal experiment,respectively.RESULTS:RASA1 protein levels were significantly decreased in RKO cells compared with the other 5 colon cancer cell lines,and RASA1 was confirmed as a target gene of mi R-21.Interestingly,RASA1 m RNA and protein levels in pre-mi R-21-LV(up-regulation of mi R-21) cells were lower than those in anti-mi R-21-LV(down-regulation of mi R-21) cells(P < 0.05).In addition,pre-mi R-21-LV or si RASA1(down-regulation of RASA1) cells showed higher cell proliferation,reduced apoptosis,increased expression of RAS-GTP,p-AKT,Raf-1,KRAS,and p-ERK1/2,and higher invasion and tumor formation ability,compared with control,antimi R-21-LV or pc DNA3.1-RASA1(up-regulation of RASA1) cells(P < 0.05).CONCLUSION:RASA1 is a target gene of mi R-21,which promotes malignant behaviors of RKO cells through regulation of RASA1 expression. | Bo Gong Wan-Wei Liu Wen-Jing Nie Dong-Feng Li Zi-Jun Xie Chao Liu Yan-Hui Liu Ping Mei Zi-Jun Li | 2015 | World Journal of Gastroenterology2015，21，5： | 6 |
| 10 | Integrated approach for optimal island partition and power dispatch显示文摘Operating in island mode when failure occurs in sure to maintain an uninterrupted power supply to significant loads. A two-stage approach that integrates optimal island partition and power dispatch is proposed in this paper, considering photovoltaics(PVs), batteries(BEs) and electric vehicles(EVs) as the power sources. In the first stage, energy indices are defined to describe the energy demand and the maximum energy that these distributed energy resources(DERs) can provide, and islands are partitioned based on an energy constraint. Considering the variability the loads and PVs, the energy constraint is a necessary but not sufficient condition for island operation,so in the second stage, a power dispatch model is proposed the active distribution network(ADN) is an effective mea-as a test for the island partition result. Sequential power flow is also simulated to guarantee a feasible and optimized island status. The situations when the tests are not passed are analyzed and classified, and corresponding modifications for the first stage model are provided. Multiple levels of constraints based on the energy index are established for the island partition model. The proposed approach has been validated through simulation using a modified IEEE 69-bus system which is divided into three districts with different load variability characteristics. | Junpeng ZHU Wei GU Ping JIANG Zhi WU Xiaodong YUAN Yinghui NIE | 2018 | Journal of Modern Power Systems and Clean Energy2018，6，3： | 6 |
| 11 | Epidemiology of urticaria in China:a population-based study显示文摘Background:Urticaria is a common skin disease characterized by episodes of wheals,and it has a negative effect on patients’quality of life.Large-scale population-based epidemiological studies of urticaria are scarce in China.The aim of this survey was to determine the prevalence,clinical forms,and risk factors of urticaria in the Chinese population.Methods:This survey was conducted in 35 cities from 31 provinces,autonomous regions,and municipalities of China.Two to three communities in each city were selected in this investigation.Participants completed questionnaires and received dermatological examinations.We analyzed the prevalence,clinical forms,and risk factors of urticaria.Results:In total,44,875 questionnaires were distributed and 41,041 valid questionnaires were collected(17,563 male and 23,478 female participants).The lifetime prevalence of urticaria was 7.30%,with 8.26%in female and 6.34%in male individuals(P<0.05).The point prevalence of urticaria was 0.75%,with 0.79%in female and 0.71%in male individuals(P<0.05).Concomitant angioedema was found in 6.16%of patients.Adults had a higher prevalence of urticaria than adolescents and children.Living in urban areas,exposure to pollutants,an anxious or depressed psychological status,a personal and family history of allergy,thyroid diseases,and Helicobacter pylori infection were associated with a higher prevalence of urticaria.Smoking was correlated with a reduced risk of urticaria.Conclusion:This study demonstrated that the lifetime prevalence of urticaria was 7.30%and the point prevalence was 0.75%in the Chinese population;women had a higher prevalence of urticaria than men.Various factors were correlated with urticaria. | Jiaqing Li Dandan Mao Shuoshuo Liu Ping Liu Jing Tian Chenhong Xue Xiaojing Liu Ruiqun Qi Bingxue Bai Jianjun Nie Siqi Ye Yu Wang Yuye Li Qing Sun Juan Tao Shuping Guo Hong Fang Jianqin Wang Qiri Mu Quanzhong Liu Yan Ding Jianzhong Zhang | 2022 | Chinese Medical Journal2022，，11： | 6 |
| 12 | Research Data Management Implementation at Peking University Library:Foster and Promote Open Science and Open Data显示文摘Research Data Management(RDM)has become increasingly important for more and more academic institutions.Using the Peking University Open Research Data Repository(PKU-ORDR)project as an example,this paper will review a library-based university-wide open research data repository project and related RDM services implementation process including project kickoff,needs assessment,partnerships establishment,software investigation and selection,software customization,as well as data curation services and training.Through the review,some issues revealed during the stages of the implementation process are also discussed and addressed in the paper such as awareness of research data,demands from data providers and users,data policies and requirements from home institution,requirements from funding agencies and publishers,the collaboration between administrative units and libraries,and concerns from data providers and users.The significance of the study is that the paper shows an example of creating an Open Data repository and RDM services for other Chinese academic libraries planning to implement their RDM services for their home institutions.The authors of the paper have also observed since the PKU-ORDR and RDM services implemented in 2015,the Peking University Library(PKUL)has helped numerous researchers to support the entire research life cycle and enhanced Open Science(OS)practices on campus,as well as impacted the national OS movement in China through various national events and activities hosted by the PKUL. | Hua Nie Pengcheng Luo Ping Fu | 2021 | Data Intelligence2021，3，1： | 5 |
| 13 | Epidermal growth factor receptor mutation analysis in cytological specimens and responsiveness to gefitinib in advanced non-small cell lung cancer patients显示文摘Background: Epidermal growth factor receptor(EGFR) mutation is the key predictor of EGFR tyrosine kinase inhibitors(TKIs) efficacy in non-small cell lung cancer(NSCLC). We conducted this study to verify the feasibility of EGFR mutation analysis in cytological specimens and investigate the responsiveness to gefitinib treatment in patients carrying EGFR mutations.Methods: A total of 210 cytological specimens were collected for EGFR mutation detection by both direct sequencing and amplification refractory mutation system(ARMS). We analyzed EGFR mutation status by both methods and evaluated the responsiveness to gefitinib treatment in patients harboring EGFR mutations by overall response rate(ORR), disease control rate(DCR) and progression free survival(PFS).Results: Of all patients, EGFR mutation rate was 28.6%(60/210) by direct sequencing and 45.2%(95/210) by ARMS(P<0.001) respectively. Among the EGFR wild type patients tested by direct sequencing, 26.7% of them were positive by ARMS. For the 72 EGFR mutation positive patients treated with gefitinib, the ORR, DCR and median PFS were 69.4%, 90.2% and 9.3 months respectively. The patients whose EGFR mutation status was negative by direct sequencing but positive by ARMS had lower ORR(48.0% vs. 80.9%, P=0.004) and shorter median PFS(7.4 vs. 10.5 months, P=0.009) as compared with that of EGFR mutation positive patients by both detection methods. Conclusions: Our study verified the feasibility of EGFR analysis in cytological specimens in advanced NSCLC. ARMS is more sensitive than direct sequencing in EGFR mutation detection. EGFR Mutation status tested on cytological samples is applicable for predicting the response to gefitinib. Abundance of EGFR mutations might have an influence on TKIs efficacy. | Lin Li Zijin Zhang Zhixin Bie Zheng Wang Ping Zhang Xin Nie Yuanming Li Hui Wang Bin Ai Gang Cheng | 2015 | Chinese Journal of Cancer Research2015，27，3： | 5 |
| 14 | Altered diaphragmatic contractile properties after high airway pressure controlled mechanical ventilation显示文摘 | JIAO Guang-yu LIU Chun-li NIE Zhi-wei LIU Dong-juan HE Ping LIU Jing XIA Ning LI Gen-song | 2006 | Chinese Medical Journal2006，，2： | 5 |
| 15 | Apolipoprotein E Gene Polymorphisms Are Risk Factors for Spontaneous Intracerebral Hemorrhage:A Systematic Review and Meta-analysis显示文摘Intracerebral hemorrhage(ICH)is a serious clinical disease with high morbidity,whose pathogenesis might be related to apolipoprotein E(APOE)gene polymorphisms.To comprehensively evaluate the risk factors for ICH occurrence,we performed a meta-analysis.We searched online databases to identify eligible studies based on the relationship between APOE genetic polymorphisms and ICH occurrence risk.Specific and pooled odds ratios(ORs)were calculated and by assessing small study bias,we drew the relationship between APOE polymorphisms and ICH risk.We included 15 eligible studies in our study containing a total of 1642 ICH samples and 5545 normal controls.The comparison of e4 andε3 APOE genotypes revealed that specific and pooled ORs showed a significantly increased odds ratio in ICH patients with theε4 genotype,indicating thatε4 gene is a risk factor for ICH occurrence,and the heterogeneity is acceptable.Similarly,it was found that theε2 genotype also contributed to the incidence rate of ICH.However,after the subgroup analysis by ethnicity,this APOE genetic polymorphism acted as a harmful factor only in white populations,but did not show an effect in Asian populations.It was suggested that both 82 andε4 APOE alleles were risk factors for ICH in general.They were risk factors in white populations only,neither had a detectable effect in Asian populations after subgroup analysing by ethnicity. | Hao NIE Yang HU Na LIU Ping ZHANG Gai-gai LI Yan-yan LI Chao PAN Hai-han YU Qian WU Guo-feng WU Zhou-ping TANG | 2019 | Current Medical Science2019，39，1： | 4 |
| 16 | Power Network Lightning Accident Quick Inquiry with the Lightning Location System显示文摘目前,闪电是 10 自然灾难之一,并且它也是力量打断的最高的环境因素。它经常引起巨大的损失到电的系统。自从 1980 年代末,中国和科技的 Huazhong 大学的州的格子公司的武汉高电压研究所一直在研究并且发展中闪电地点系统(LLS ) 。在 mid-1990s,一个闪电察觉网络在中国在 29 个省和城市被创造。很快发现闪电事故首先被使用,还原剂它极大地驱动打断。另外,它保证高效率和电系统的安全操作。显著利益被完成。中国的 LLS 通过了一“放的取向 - 放的时差 - 综合的放”开发过程。放的精确,察觉效率,自动化的学位,有实行可能和应用范围被改进。另外,国家网络的一个闪电信息系统计划被实现了,它满足整个协会。 | NIE Zhiping ZHAO Wenguang ZHANG Ping WEN Yinping CHEN Weijiang | 2008 | Geo-Spatial Information Science2008，11，1： | 4 |
| 17 | Abnormal Effective Connectivity of the Anterior Forebrain Regions in Disorders of Consciousness显示文摘A number of studies have indicated that disorders of consciousness result from multifocal injuries as well as from the impaired functional and anatomical connectivity between various anterior forebrain regions.However, the specific causal mechanism linking these regions remains unclear. In this study, we used spectral dynamic causal modeling to assess how the effective connections(ECs) between various regions differ between individuals. Next, we used connectome-based predictive modeling to evaluate the performance of the ECs in predicting the clinical scores of DOC patients. We found increased ECs from the striatum to the globus pallidus as well as from the globus pallidus to the posterior cingulate cortex, and decreased ECs from the globus pallidus to the thalamus and from the medial prefrontal cortex to the striatum in DOC patients as compared to healthy controls.Prediction of the patients' outcome was effective using the negative ECs as features. In summary, the present study highlights a key role of the thalamo-basal ganglia-cortical loop in DOCs and supports the anterior forebrain mesocircuit hypothesis. Furthermore, EC could be potentially used to assess the consciousness level. | Ping Chen Qiuyou Xie Xiaoyan Wu Huiyuan Huang Wei Lv Lixiang Chen Yequn Guo Shufei Zhang Huiqing Hu You Wang Yangang Nie Ronghao Yu Ruiwang Huang | 2018 | Neuroscience Bulletin2018，34，4： | 4 |
| 18 | Cosmogenic nuclide burial age of the Sanying Formation and its implications显示文摘The Pliocene fluvial/lacustrine sediments of the Sanying Formation lie along the Red River fault and its northwest extension;their majority outcrops appear around Eryuan.The Sanying Formation is characterized by multiple intercalated coal layers and its unconformities contact with the underlying Triassic limestone and the overlying Quaternary coarse sediments.Cosmogenic nuclide burial dating confirms the Pliocene age of the Sanying Formation.The burial ages of the overlying Quaternary sediments provide the lower age limit of the Sanying Formation:2 Ma.Detrital zircon U-Pb age distribution suggests provenance of the Sanying Formation traced to the Songpan-Ganzi flysch belt.From the spatial distribution as well as sedimentary and fault ages,we found a strong connection of the Sanying Formation with the Red River and the Jianchuan faults.We therefore propose that activation of the Red River and the Jianchuan faults during the Late Miocene resulted in subsidence of basins in the extensional areas around Eryuan and in the middle to south segments of the Red River fault.The basins were filled with water carried by the Jinsha River and overflow-lakes formed within the basins where the Sanying Formation was deposited.Most of the lakes were dried and sedimentation of the Sanying Formation ceased due to the uplift of the Yunling Mountains,which forced rerouting of the Jinsha River at the beginning of Quaternary. | ZHENG Yong JIA Jun NIE XiKe KONG Ping | 2014 | Science China Earth Sciences2014，57，6： | 4 |
| 19 | Wildlife conservation and management in China:achievements,challenges and perspectives显示文摘Dramatic global changes to the environment have wrought unprecedented reductions in biodiversity, with>28%species assessed by the International Union for Conservation of Nature(IUCN) under the threat of extinction[1]. China, as one of the world’s megadiverse countries, plays a critical role in global biodiversity conservation. | Guangping Huang Xiaoge Ping Weihua Xu Yibo Hu Jiang Chang Ronald R.Swaisgood Jiang Zhou Xiangjiang Zhan Zejun Zhang Yonggang Nie Jie Cui Michael Bruford Zhihe Zhang Baoguo Li Li Zhang Zhi Lv Fuwen Wei | 2021 | National Science Review2021，8，7： | 4 |
| 20 | Effect of Interplanting with Zero Tillage and Straw Manure on Rice Growth and Rice Quality显示文摘The interplanting with zero-tillage of rice, i.e. direct sowing rice 10-20 days before wheat harvesting, and remaining about 30-cm high stubble after cutting wheat or rice with no tillage, is a new cultivation technology in wheat-rice rotation system. To study the effects of interplanting with zero tillage and straw manure on rice growth and quality, an experiment was conducted in a wheat-rotation rotation system. Four treatments, i.e. ZIS (Zero-tillage, straw manure and rice interplanting), ZI (Zero-tillage, no straw manure and rice interplanting), PTS (Plowing tillage, straw manure and rice transplanting), and PT (Plowing tillage, no straw manure and rice transplanting), were used. ZIS reduced plant height, leaf area per plant and the biomass of rice plants, but the biomass accumulation of rice at the late stage was quicker than that under conventional transplanting cultivation. In the first year (2002), there was no significant difference in rice yield among the four treatments. However, rice yield decreased in interplanting with zero-tillage in the second year (2003). Compared with the transplanting treatments, the number of filled grains per panicle decreased but 1000-grain weight increased in interplanting with zero-tillage, which were the main factors resulting in higher yield. Interplanting with zero-tillage improved the milling and appearance qualities of rice. The rates of milled and head rice increased while chalky rice rate and chalkiness decreased in interplanting with zero-tillage. Zero-tillage and interplanting also affected rice nutritional and cooking qualities. In 2002, ZIS showed raised protein content, decreased amylose content, softer gel consistency, resulting in improved rice quality. In 2003, zero-tillage and interplanting decreased protein content and showed similar amylose content as compared with transplanting treatments. Moreover, protein content in PTS was obviously increased in comparison with the other three treatments. The rice in interplanting with zero-tillage treatments had higher peak viscosity and breakdown, lower setback, showing better rice taste quality. The straw manure had no significant effect on rice viscosity under interplanting with zero-tillage, but had the negative influence on the rice taste quality under transplanting with plowing tillage. | LIU Shi ping NIE Xin tao DAI Qi gen Huo Zhong yang XU Ke | 2007 | Rice science2007，14，3： | 2 |
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