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2篇 您的检索式:作者名="R.Flores"
    题名 作者 年代 出处 被引量
1Applying FAIR Principles to Plant Phenotypic Data Management in GnpIS显示文摘GnpIS is a data repository for plant phenomics that stores whole field and greenhouse experimental data including environment measures.It allows long-term access to datasets following the FAIR principles:Findable,Accessible,Interoperable,and Reusable,by using a flexible and original approach.It is based on a generic and ontology driven data model and an innovative software architecture that uncouples data integration,storage,and querying.It takes advantage of international standards including the Crop Ontology,MIAPPE,and the Breeding API.GnpIS allows handling data for a wide range of species and experiment types,including multiannual perennial plants experimental network or annual plant trials with either raw data,i.e.,direct measures,or computed traits.It also ensures the integration and the interoperability among phenotyping datasets and with genotyping data.This is achieved through a careful curation and annotation of the key resources conducted in close collaboration with the communities providing data.Our repository follows the Open Science data publication principles by ensuring citability of each dataset.Finally,GnpIS compliance with international standards enables its interoperability with other data repositories hence allowing data links between phenotype and other data types.GnpIS can therefore contribute to emerging international federations of information systems.C.Pommier C.Michotey G.Cornut P.Roumet E.Duchêne R.Flores A.Lebreton M.Alaux S.Durand E.Kimmel T.Letellier G.Merceron M.Laine C.Guerche M.Loaec D.Steinbach M.A.Laporte E.Arnaud H.Quesneville A.F.Adam-Blondon 2019Plant Phenomics2019,1,1:6
2C19MC miRNA-520G induces SP100 antiviral gene transcription and inhibits melanin production in skin cutaneous melanoma显示文摘SP100 is an antiviral protein that restricts the productive stage of human papillomavirus(HPV)and multiple other viruses,and viruses in turn block sUMO-1-mediated stabilization of SP100 and promotes its degradation(Table S1).Interferon(IFN)signaling could still produce more SP100 through transcription to counteract viruses.1 Viruses also disable the transcriptional up-regulation of SP100 to achieve persistent infection in hosts.Goodwin G.Jinesh Marian T.Smallin Nino Mtchedlidze Isha Godwin Marco Napoli Nicole Hackel Manali S.Phadke Avani A.Deshpande Xiaobo Li John H.Lockhart Jaden R.Baldwin Suehelay Acevedo-Acevedo Yifeng Gao Michelle A.Reiser Keiran S.M.Smalley Elsa R.Flores Andrew S.Brohl 2024Genes & Diseases2024,11,1:0
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