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6篇 您的检索式:作者名="Raffaele Nardone"
    题名 作者 年代 出处 被引量
1Spinal cord involvement in patients with cirrhosis显示文摘A severe spinal cord involvement may rarely occur in patients with cirrhosis and other chronic liver diseases;this complication is usually associated with overt liver failure and surgical or spontaneous porto-systemic shunt.Hepatic myelopathy(HM)is characterized by progressive weakness and spasticity of the lower extremities,while sensory and sphincter disturbances have rarely been described and are usually less important.The diagnosis is assigned in the appropriate clinical setting on clinical grounds after the exclusion of other clinical entities leading to spastic paraparesis.Magnetic resonance imaging is often unremarkable;however,also intracerebral corticospinal tract abnor-malities have been reported recently.The study of motor evoked potentials may disclose central conduction abnormalities even before HM is clinically manifest.HM responds poorly to blood ammonia-lowering and other conservative medical therapy.Liver transplantation represents a potentially definitive treatment for HM in patients with decompensated cirrhosis of Child-Pugh B and C grades.Other surgical treatment options in HM include surgical ligation,shunt reduction,or occlusion by interventional procedures.Raffaele Nardone Yvonne Hller Monica Storti Piergiorgio Lochner Frediano Tezzon Stefan Golaszewski Francesco Brigo Eugen Trinka 2014World Journal of Gastroenterology2014,20,10:12
2How the brain can rewire itself after an injury: the lesson from hemispherectomy显示文摘Does a post-lesional rewiring exist in the central nervous system(CNS)?Whereas neuroimaging and neuromodulation techniques illustrate the extensive cortical reshaping after a brain injury,the remodeling of ascending and descending neuronal pathway is more difficult to be investigated.Here,we discuss how the studies dealing with hemispherectomy(HS)can provide interesting information about the functional and anatomical reorganization which take place after an extensive unilateral lesion.Indeed,studies in humans and animal models of HS clearly illustrate that the brain isLuca Sebastianelli Leopold Saltuari Raffaele Nardone 2017Neural Regeneration Research2017,12,9:1
3Cholinergic dysfunction in subcortical ischaemic vascular dementia: a transcranial magnetic stimulation study显示文摘Raffaele Nardone Jürgen Bergmann Frediano Tezzon Günther Ladurner Stefan Golaszewski 2008Journal of Neural Transmission2008,,5:1
4Reorganization of spinal neural circuitry and functional recovery after spinal cord injury显示文摘The ability of the adult central nervous system to reorganize its circuits over time is the key to understand the functional improvement in subjects with spinal cord injury(SCI).Adaptive changes within spared neuronal circuits may occur at cortical,brainstem,or spinal cord level,both above and below a spinal lesion(Bareyre et al.,2004).At each level the reorganization is a very dynamic process,and its degree is highly variable,depending on several factors,including the age ofRaffaele Nardone Eugen Trinka 2015Neural Regeneration Research2015,10,2:0
5Enhanced motor cortex excitability after spinal cord injury显示文摘Transcranial magnetic stimulation(TMS)represents a useful non-invasive approach to studying cortical physiology,in addition to the descending motor pathways(Hallett,2000),and may also be used to investigate the intracortical facilitatory and inhibitory mechanisms.Nardone Raffaele 2015Neural Regeneration Research2015,10,12:0
6Ipsilateral motor evoked potentials in a patient with unihemispheric cortical atrophy due to Rasmussen encephalitis显示文摘The role of the ipsilaterally descending motor pathways in the recovery mechanisms after unilateral hemispheric damage is still poorly understood. Motor output reorganization was investigated in a 56-year-old male patient with acquired unilateral hemispheric atrophy due to Rasmussen encephalitis. In particular,the ipsilateral corticospinal pathways were explored using focal transcranial magnetic stimulation. In the first dorsal interosseous and wrist extensors muscles, the median amplitudes of the ipsilateral motor evoked potentials induced by transcranial magnetic stimulation in the patient were higher than those of 10 age-matched healthy control subjects. In the biceps brachii muscle, the median amplitudes of the ipsilateral motor evoked potentials were the second largest in the patient compared to the controls. This study demonstrated a reinforcement of ipsilateral motor projections from the unaffected motor cortex to the hemiparetic hand in a subject with acquired unihemispheric cortical damage.Raffaele Nardone Patrick B.Langthaler Andrea Orioli Viviana Versace Giuditta Ilaria Scarano Francesco Brigo Leopold Saltuari Luca Carnicelli Eugen Trinka Luca Sebastianelli 2019Neural Regeneration Research2019,14,6:0
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