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| 1 | Treatment options for unstable trochanteric fractures: Screw or helical proximal femoral nail显示文摘Purpose: To compare treatment outcome of screw proximal femoral nail (PFN) system with that of a helical PFN. Methods: The study included 77 patients with closed unstable intertrochanteric fracture classified as AO 31A2 & 31A3, between June 2008 to August 2011. Inclusion criteria were: all mature skeletons above 50 years of age; closed unstable trochanteric fracture classified as AO 31A2 & A3. Exclusion criteria were: immature skeleton, pathological fracture of any cause other than osteoporosis, inability to walk inde- pendently prior to injury. Patients were randomized to 2 treatment groups based on admission sequence. Forty patients were treated with screw PFN and thirty seven were treated with helical PFN. Results: Both groups were similar in respect of time of surgery, blood loss and functional assessment and duration of hospitalization. In screw PFN group 2 patients had superficial wound infection, 1 patient had persistent hip pain and 1 patient had shortening 〉1 cm but 〈2 cm, while in helical PFN group 1 patient had superficial wound infection. Conclusion: Both screw and helical PFN are very effective implants in osteoporotic and unstable trochanteric fractures even in Indian patients where the bones are narrow and neck diameter is small. It is an implant of choice for osteooorotic and unstable trochanteric fractures. | Jeetendra Bajpai Rajesh Maheshwari Akansha Bajpai Sumit Saini | 2015 | Chinese Journal of Traumatology2015，18，6： | 9 |
| 2 | 人工全膝关节置换后股骨假体角度的CT影像学评估:股骨外上髁线参照与间隙平衡技术的对比研究(英文)显示文摘[目的]虽然人工全膝关节置换术中假体旋转定位的重要性已得到公认,但术中以哪条轴线为参照能够更加精确的保证股骨假体的旋转定位,目前尚存争议。研究表明股骨外上髁线(TEA)与膝关节屈曲轴线平行,但这一轴线术中难以精确确定。本文采用间隙平衡技术(BG),对比TEA技术在股骨假体实际旋转角度测量的差异。[方法]30例人工全膝关节置换分为2组(每组15膝),分别采用TEA和BG技术,术后行CT扫描测量股骨假体旋转角度并行膝关节学会评分(KSS)。[结果]BG组中股骨假体平均外旋角度为2.7°±1.1°,TEA组为5.6°±1.6°(P=0.001)。术后KSS功能评分改善BG组高于TEA组(P=0.002),但两组的KSS膝评分无显著性差异(P=0.39)。[结论]研究表明,与BG技术相比,术中应用TEA参照确定股骨假体的旋转定位可导致股骨假体的过度外旋,其术后KSS功能评分亦较差。 | Shrinand V Vaidya Aditya V Maheshwari Rajesh M Gadhiya Vaibhav Bagaria Amar S Ranawat Chitranjan S Ranawat | 2008 | 中国矫形外科杂志2008，16，12： | 2 |
| 3 | Multiple molecular targets in cancer chemoprevention by curcumin显示文摘 | Rajesh L. Thangapazham Anuj Sharma Radha K. Maheshwari | 2006 | The AAPS Journal2006，，3： | 1 |
| 4 | Multiple molecular targets in cancer chemoprevention by curcumin显示文摘 | Rajesh L. Thangapazham Anuj Sharma Radha K. Maheshwari | 2006 | The AAPS Journal2006，，3： | 1 |
| 5 | Multiple molecular targets in cancer chemoprevention by curcumin显示文摘 | Rajesh L. Thangapazham Anuj Sharma Radha K. Maheshwari | 2006 | The AAPS Journal2006，，3： | 1 |
| 6 | Global variation in skin injures and skincare practices in extremely preterm infants显示文摘Background Globally,are skincare practices and skin injuries in extremely preterm infants comparable?This study describes skin injuries,variation in skincare practices and investigates any association between them.Methods A web-based survey was conducted between February 2019 and August 2021.Quantifying skin injuries and describing skincare practices in extremely preterm infants were the main outcomes.The association between skin injuries and skincare practices was established using binary multivariable logistic regression adjusted for regions.Results Responses from 848 neonatal intensive care units,representing all geographic regions and income status groups were received.Diaper dermatitis(331/840,39%)and medical adhesive-related skin injuries(319/838,38%)were the most common injuries.Following a local skincare guideline reduced skin injuries[medical adhesive-related injuries:adjusted odds ratios(aOR)=0.63,95%confidence interval(CI)=0.45–0.88;perineal injuries:aOR=0.66,95%CI=0.45–0.96;local skin infections:OR=0.41,95%CI=0.26–0.65;chemical burns:OR=0.46,95%CI=0.26–0.83;thermal burns:OR=0.51,95%CI=0.27–0.96].Performing skin assessments at least every four hours reduced skin injuries(abrasion:aOR=0.48,95%CI=0.33–0.67;pressure:aOR=0.51,95%CI=0.34–0.78;diaper dermatitis:aOR=0.71,95%CI=0.51–0.99;perineal:aOR=0.52,95%CI=0.36–0.75).Regional and resource settings-based variations in skin injuries and skincare practices were observed.Conclusions Skin injuries were common in extremely preterm infants.Consistency in practice and improved surveillance appears to reduce the occurrence of these injuries.Better evidence regarding optimal practices is needed to reduce skin injuries and minimize practice variations. | Pranav Jani Umesh Mishra Julia Buchmayer Rajesh Maheshwari Daphne D’Çruz Karen Walker Duygu Gözen Krista Lowe Audrey Wright James Marceau Mihaela Culcer Archana Priyadarshi Adrienne Kirby James EMoore Ju Lee Oei Vibhuti Shah Umesh Vaidya Abdelmoneim Khashana Sunit Godambe Fook Choe Cheah Wen-Hao Zhou Xiao-Jing Hu Muneerah Satardien | 2023 | World Journal of Pediatrics2023，19，2： | 1 |
| 7 | Systemic postnatal corticosteroid use for the prevention of bronchopulmonary dysplasia and its relationship to early neurodevelopment in extremely preterm显示文摘Background Systemic postnatal corticosteroid use in extremely preterm infants poses a risk of adverse neurodevelopmental outcomes.This study explores their use beyond seven days of age with early neurodevelopmental assessments during the fidgety period(9-20 weeks postterm age).Methods This retrospective single-center cohort study included inborn extremely preterm infants from 1 January 2014 to 31 December 2018.Outborn infants,those with congenital or genetic abnormalities,and those who received postnatal cor-ticosteroids for nonrespiratory reasons were excluded.The cohort was dichotomized based on the status of corticosteroid receipt.Early neurodevelopmental outcomes were reported using Prechtl's General Movements Assessment.Results Of the 282 infants,67(23.75%)received corticosteroids.Of these,34(50.75%)received them for dependency on invasive ventilation(intermittent positive-pressure ventilation),and the remainder received them for dependency on non-invasive ventilation continuous positive airway pressure(CPAP)or bi-level positive airway pressure(BiPAP).Abnormal or absent fidgety movements were observed in 13% of infants(7/54)who received corticosteroids compared to 2% of infants(3/146)who did not.An increased odds for an abnormal general movements assessment from corticosteroid use after adjusting for gestational age[adjusted odds ratio(aOR)=5.5,95% confidence interval(CI)=1.14-26.56]was observed.The motor optimality scores differed between the two groups[corticosteroid group:25.5(23-26)versus no-corticosteroid group:26(24-28);z=-2.02].A motor optimality score<20 was observed in 14.8% of infants(8/54)in the corticosteroid group compared to 2% of infants(3/146)in the noncorticosteroid group.This difference was significant after adjustment for gestational age(aOR 5.96,95%CI 1.28-27.74).Conclusions Abnormal early neurodevelopment was observed in infants who received systemic postnatal corticosteroids.The relationship between these findings and other factors influencing early neurodevelopment needs further exploration. | Emilia Esterman Traci-Anne Goyen Pranav Jani Gemma Lowe Jane Baird Rajesh Maheshwari Daphne D’Cruz Melissa Luig Dharmesh Shah | 2023 | World Journal of Pediatrics2023，19，6： | 0 |
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