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| 1 | Small RNA Profiling Reveals Phosphorus Deficiency as a Contributing Factor in Symptom Expression for Citrus Huanglongbing Disease显示文摘Huanglongbing (HLB ) 是与类 Candidatus Liberibacter 的细菌被联系的破坏柠檬疾病(Ca。L.) 。强大的诊断工具和管理策略被需要控制 HLB。小 RNA (sRNA ) 玩的主人在调整主人回答到病原体感染的一个重要角色并且为许多人的疾病被用作早诊断的标记,包括癌症。决定是否柠檬 sRNAs 调整主人回答到 HLB, sRNAs 从柠檬 sinensis 被介绍有 Ca 的 10 和 14 星期柱子 grafting。L。asiaticus (Las ) 积极或健康的织物。十新 microRNAs (miRNAs ) , 76 保存 miRNAs,和许多小介入 RNA (siRNAs ) 被发现。几 miRNAs 和 siRNAs 被 Las 感染高度导致,并且能潜在地被开发进 HLB 的早诊断标记。miR399,被磷饥饿在另外的植物种类导致,被与类似于 HLB 的症状引起柠檬 stubborna 疾病的 Las 然而并非 Spiroplasma citri 的感染明确地导致。我们与健康的树相比在 Las 积极的柠檬树上发现了磷的 35% 减小。HLB 积极的香甜的橘子树的适用的磷 oxyanion 答案减少了 HLB 症状严厉并且显著地在西南佛罗里达在 3 年的地试用期间改进了水果生产。我们的分子,生理,并且地数据建议那磷缺乏被连接到 HLB 疾病 symptomology。 | Hongwei Zhao Ruobai Sun Ute Albrecht Chellappan Padmanabhan Airong Wanga Michael D. Coffey Thomas Girke Zonghua Wang Timothy J. Close Mikeal Roose Raymond K. Yokomi Svetlana Folimonova Georgios Vidalakis Robert Rouse Kim D. Bowman Hailing Jin | 2013 | Molecular Plant2013，6，2： | 12 |
| 2 | 儿童前庭性偏头痛和儿童复发性眩晕:Bárány协会前庭疾病分类委员会和国际头痛协会诊断标准共识文件显示文摘本文介绍了Bárány协会国际前庭疾病分类(International Classification of Vestibular Disorders,ICVD)委员会和国际头痛协会偏头痛分类小组所提出的'儿童前庭性偏头痛'(vestibular migraine of childhood,VMC)、'很可能的儿童前庭性偏头痛'(probable VMC,pVMC)和'儿童复发性眩晕'(recurrent vertigo of childhood,RVC)的诊断标准。偏头痛在儿童期不同复发性眩晕亚型中起着重要作用。在此分类文件中,VMC、p VMC和RVC这3种与偏头痛相关的一组谱系疾病分类,上述诊断标准中的偏头痛成分为确定、很可能及可能不存在。VMC的诊断标准:(A)至少5次中度或重度前庭症状发作,持续时间5分钟~72小时;(B)当前或既往有伴或不伴先兆的偏头痛病史;(C)至少50%的发作与至少1种偏头痛样症状相关。pVMC的诊断标准:至少3次中度或重度前庭症状发作,持续时间5分钟~72小时,符合VMC诊断标准B或C中的1项。RVC的诊断标准:至少3次中度或重度前庭症状发作,持续时间为1分钟~72小时,VMC诊断标准中的B和C均不符合。对于以上3种疾病,患者的年龄必须<18岁。建议将来的研究应特别关注RVC,以研究和确定其可能的亚型及其与偏头痛的关系。 | 凌霞(译) 张赛(译) 申博(译) 隋汝波(审校) 杨旭(审校) Raymond van de Berg Josine Widdershoven Alexandre Bisdorff Stefan Evers Sylvette Wiener-Vacher Sharon LCushing Kenneth JMack Ji Soo Kim Klaus Jahn Michael Strupp Thomas Lempert | 2021 | 神经损伤与功能重建2021，16，8： | 5 |
| 3 | Evolutionary Optimization: Pitfalls and Booby Traps显示文摘Evolutionary computation (EC), a collective name for a range of metaheuristic black-box optimization algorithms, is one of the fastest-growing areas in computer science. Many manuals and 'how-to's on the use of different EC methods as well as a variety of free or commercial software libraries are widely available nowadays. However, when one of these methods is applied to a real-world task, there can be many pitfalls and booby traps lurking - certain aspects of the optimization problem that may lead to unsatisfactory results even if the algorithm appears to be correctly implemented and executed. These include the convergence issues, ruggedness, deceptiveness, and neutrality in the fitness landscape, epistasis, non-separability, noise leading to the need for robustness, as well as dimensionality and scalability issues, among others. In this article, we systematically discuss these related hindrances and present some possible remedies. The goal is to equip practitioners and researchers alike with a clear picture and understanding of what kind of problems can render EC applications unsuccessful and how to avoid them from the start. | Thomas Weise Raymond Chiong Ke Tang | 2012 | Journal of Computer Science & Technology2012，27，5： | 5 |
| 4 | ACC/AHA guidelines for the management of patients with unstable angina and non–st-segment elevation myocardial infarction显示文摘 | Eugene Braunwald Elliott M Antman John W Beasley Robert M Califf Melvin D Cheitlin Judith S Hochman Robert H Jones Dean Kereiakes Joel Kupersmith Thomas N Levin Carl J Pepine John W Schaeffer Earl E Smith David E Steward Pierre Theroux Raymond J Gibbons J | 2000 | Journal of the American College of Cardiology2000，，3： | 4 |
| 5 | Academic Emotions in Students’ Self-Regulated Learning and Achievement: A Program of Qualitative and Quantitative Research显示文摘 | Reinhard Pekrun Thomas Goetz Wolfram Titz Raymond P. Perry | 2002 | Educational Psychologist2002，，2： | 3 |
| 6 | Sofosbuvir and Ribavirin Prevent Recurrence of HCV Infection after Liver Transplantation: An Open-Label Study显示文摘 | Michael P. Curry Xavier Forns Raymond T. Chung Norah A. Terrault Robert Brown Jonathan M. Fenkel Fredric Gordon Jacqueline O’Leary Alexander Kuo Thomas Schiano Gregory Everson Eugene Schiff Alex Befeler Edward Gane Sammy Saab John G. McHutchison G. Mani S | 2014 | Gastroenterology2014，，： | 3 |
| 7 | A New Era in Esophageal Diagnostics: The Image-Based Paradigm of High-Resolution Manometry显示文摘 | Renato Salvador Attila Dubecz Marek Polomsky Oliver Gellerson Carolyn E. Jones Daniel P. Raymond Thomas J. Watson Jeffrey H. Peters | 2009 | Journal of the American College of Surgeons2009，，6： | 2 |
| 8 | Laser patterning for the study of MSC cardiogenic differentiation at the single-cell level显示文摘Mesenchymal stem cells(MSCs)have been cited as contributors to heart repair through cardiogenic differentiation and multiple cellular interactions,including the paracrine effect,cell fusion,and mechanical and electrical couplings.Due to heart–muscle complexity,progress in the development of knowledge concerning the role of MSCs in cardiac repair is heavily based on MSC–cardiomyocyte coculture.In conventional coculture systems,however,the in vivo cardiac muscle structure,in which rod-shaped cells are connected end-to-end,is not sustained;instead,irregularly shaped cells spread randomly,resulting in randomly distributed cell junctions.Consequently,contact-mediated cell–cell interactions(e.g.,the electrical triggering signal and the mechanical contraction wave that propagate through MSC–cardiomyocyte junctions)occur randomly.Thus,the data generated on the beneficial effects of MSCs may be irrelevant to in vivo biological processes.In this study,we explored whether cardiomyocyte alignment,the most important phenotype,is relevant to stem cell cardiogenic differentiation.Here,we report(i)the construction of a laser-patterned,biochip-based,stem cell–cardiomyocyte coculture model with controlled cell alignment;and(ii)single-cell-level data on stem cell cardiogenic differentiation under in vivo-like cardiomyocyte alignment conditions. | Zhen Ma Qiuying Liu Huaxiao Yang Raymond B Runyan Carol A Eisenberg Meifeng Xu Thomas K Borg Roger Markwald Yifei Wang Bruce Z Gao | 2013 | Light(Science & Applications)2013，2，1： | 2 |
| 9 | Valsartan benefits left ventricular structure and function in heart failure: Val-HeFT echocardiographic study显示文摘 | Maylene Wong Lidia Staszewsky Roberto Latini Simona Barlera Alberto Volpi Yann-Tong Chiang Raymond L Benza Sidney O Gottlieb Thomas D Kleemann Franco Rosconi Pieter M Vandervoort Jay N Cohn | 2002 | Journal of the American College of Cardiology2002，，： | 1 |
| 10 | Theoretical studies of high-temperature multilayer thermal insulations using radiation scaling显示文摘 | Markus Spinnler Edgar R.F. Winter Raymond Viskanta Thomas Sattelmayer | 2003 | Journal of Quantitative Spectroscopy and Radiative Transfer2003，，4： | 1 |
| 11 | Treatment of Hepatitis C in Renal Transplantation Candidates: A Single-Center Experience显示文摘 | T. Werner Bashar Aqel Vijayan Balan Thomas Byrne Elizabeth Carey David Douglas Raymond L. Heilman Jorge Rakela Kristin Mekeel Kunam Reddy Hugo E. Vargas | 2010 | Transplantation2010，，4： | 1 |
| 12 | Spontaneous Control of HCV Is Associated With Expression of HLA-B*57 and Preservation of Targeted Epitopes显示文摘 | Arthur Y. Kim Thomas Kuntzen Joerg Timm Brian E. Nolan Melanie A. Baca Laura L. Reyor Andrew C. Berical Andrea J. Feller Kristin L. Johnson Julian Schulze Zur Wiesch Gregory K. Robbins Raymond T. Chung Bruce D. Walker Mary Carrington Todd M. Allen Georg M | 2011 | Gastroenterology2011，，2： | 1 |
| 13 | Pathophysiologic Observations and Histopathologic Recognition of the Portal Hyperperfusion or Small-for-Size Syndrome显示文摘 | Anthony J. Demetris Dympna M. Kelly Bijan Eghtesad Paulo Fontes J. Wallis Marsh Kusum Tom Heinke P. Tan Thomas Shaw-Stiffel Linda Boig Paula Novelli Raymond Planinsic John J. Fung Amadeo Marcos | 2006 | The American Journal of Surgical Pathology2006，，8： | 1 |
| 14 | High power and good beam quality at 980 nm from a vertical external cavity surface emitting laser显示文摘 | William J Alford Thomas D Raymond | 2002 | J Opt Soc Am B2002，19，4： | 1 |
| 15 | Intramucosal esophageal adenocarcinoma: Primum non nocere显示文摘 | Zhigang Li Thomas W. Rice Xiuli Liu John R. Goldblum Sarah J. Williams Lisa A. Rybicki Sudish C. Murthy David P. Mason Daniel P. Raymond Eugene H. Blackstone | 2013 | The Journal of Thoracic and Cardiovascular Surgery2013，，： | 1 |
| 16 | The riverside and Berwyn experience: Contrasts in landscape structure, perceptions of the urban landscape, and their effects on people 显示文摘 | Thomas C Terry B Raymond D Y | 2006 | Landscape and Urban Planning2006，，75： | 1 |
| 17 | Does Erectile Dysfunction Contribute to Cardiovascular Disease Risk Prediction Beyond the Framingham Risk Score?显示文摘 | Andre B. Araujo Susan A. Hall Peter Ganz Gretchen R. Chiu Raymond C. Rosen Varant Kupelian Thomas G. Travison John B. McKinlay | 2010 | Journal of the American College of Cardiology2010，，4： | 1 |
| 18 | Evaluation of [ 18 F]-choline PET/CT for staging and restaging of prostate cancer显示文摘 | Daniela B. Husarik Raymond Miralbell Markus Dubs Hubert John Olivier T. Giger Albert Gelet Tibor Cservenyàk Thomas F. Hany | 2008 | European Journal of Nuclear Medicine and Molecular Imaging2008，，2： | 1 |
| 19 | Esophagectomy for High Grade Dysplasia is Safe, Curative, and Results in Good Alimentary Outcome显示文摘 | Valerie A. Williams Thomas J. Watson Fernando A. Herbella Oliver Gellersen Daniel Raymond Carolyn Jones Jeffrey H. Peters | 2007 | Journal of Gastrointestinal Surgery2007，，12： | 1 |
| 20 | Spontaneous Control of HCV Is Associated With Expression of HLA-B*57 and Preservation of Targeted Epitopes显示文摘 | Arthur Y. Kim Thomas Kuntzen Joerg Timm Brian E. Nolan Melanie A. Baca Laura L. Reyor Andrew C. Berical Andrea J. Feller Kristin L. Johnson Julian Schulze Zur Wiesch Gregory K. Robbins Raymond T. Chung Bruce D. Walker Mary Carrington Todd M. Allen Georg M | 2011 | Gastroenterology2011，，2： | 1 |
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