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72篇 您的检索式:作者名="Rehman L"
    题名 作者 年代 出处 被引量
1Therapeutic options for the management of pancreatic cancer显示文摘Since its initial characterization, pancreatic ductal adenocarcinoma has remained one of the most devastating and difficult cancers to treat. Pancreatic cancer is the fourth leading cause of death in the United States, resulting in an estimated 38460 deaths annually. With few screening tools available to detect this disease at an early stage, 94% of patients will die within five years of diagnosis. Despite decades of research that have led to a better understanding of the molecular and cellular signaling pathways in pancreatic cancer cells, few effective therapies have been developed to target these pathways. Other treatment options have included more sophisticated pancreatic cancer surgeries and combination therapies. While outcomes have improved modestly for these patients, more effective treatmentsare desperately needed. One of the greatest challenges in the future of treating this malignancy will be to develop therapies that target the tumor microenvironment and surrounding pancreatic cancer stem cells in addition to pancreatic cancer cells. Recent advances in targeting pancreatic stellate cells and the stroma have encouraged researchers to shift their focus to the role of desmoplasia in pancreatic cancer pathobiology in the hopes of developing newer-generation therapies. By combining novel agents with current cytotoxic chemotherapies and radiation therapy and personalizing them to each patient based on specific biomarkers, the goal of prolonging a patient's life could be achieved. Here we review the most effective therapies that have been used for the treatment of pancreatic cancer and discuss the future potential of therapeutic options.Maria L Rossi Azeem A Rehman Christopher S Gondi 2014World Journal of Gastroenterology2014,20,32:13
2Exercise acutely increases circulating endothelial progenitor cells and monocyte/macrophage-derived angiogenic cells显示文摘Rehman J Li J Parvathaneni L 2004J Am Coll Cardiol2004,43,:1
3Role of AMP-activated protein kinase in cancer therapy显示文摘REHMAN G SHEHZAD A KHAN A L 2014Arch Pharm(Weinheim)2014,347,7:1
4Use of amino-terminal pro-B-type natriuretic peptide to guide outpatient therapy of patients with chronic left ventricular systolic dysfunction 显示文摘JAMES L JANUZZI JR MD SHAFIQ U REHMAN M D ASIM A MOHAMMED M D ANJU BHARDWAJ M D LINDA BARAJAS R N JUSTINE BARAJAS HAN-NA KIM M D MPH AARON L BAGGISH M D RORY B WEINER M D ANNABEL CHEN-TOURNOUX MD JANE E MARSHALL RDCS STEPHANIE A MOORE M D WILLIAM D CARLSON M D GREGORY D LEWIS M D JORDAN SHIN M D DOROTHY SULLIVAN ANP KIMBERLY PARKS D O THOMAS J WANG M D SHAWN A GREGORY M D SHANMUGAM UTHAMALINGAM M D MARC J SEMIGRAN M D 2011J Am Coll Cardiol2011,58,18:1
5Improved vertex chain code based mapping algorithm for curve length estimation 显示文摘Haron H Rehman A Wulandhari L A 2011Journal of Computer Science2011,7,5:1
6A study of thesintering of diatomaceous earth to produce porous ceramicmonoliths with bimodal porosity and high strength显示文摘AKHTARF REHMAN Y BERGSTROM L 2010PowderTechnology2010,201,3:1
7Magnetic resonance spectroscopy:novel non-invasive technique for diagnosing brain tumors 显示文摘Rehman L Rehman UL Azmat SK 2015J Coll Physicians Surg Pak2015,25,12:1
8Treatment of articular fractures with continuous passive motion显示文摘Onderko L L Rehman S 2013Orthop Clin North Am2013,44,3:1
9Exercise acutely increases circulating endothelial progenitor cells and monocyte-/macrophage-derived angiogenic cells显示文摘Rehman J Li J Parvathaneni L 2004J Am Coll Cardiol2004,43,12:1
10Reduction in arterial stiffness with angiotensin Ⅱ antagonism and converting enzyme inhibition 显示文摘Rehman A Ismail SB Naing L 2007Am J Hypertens2007,20,2:1
11Characteristics of the novel interleukin family hiomarker ST2 in patients with acute heart failure 显示文摘REHMAN S U MUELLER T JANUZZI J L 2008JAmCollofCardiol2008,52,18:1
12Assessment of crop damage by wildlife in Chunati Wilklife Sanctuary显示文摘MIAH M D REHMAN M L AHSAN M F 2001Balgladesh Tigerpaper2001,28,4:1
13Influence of the Angiotensin Ⅱ type Ⅰ receptor gene 1166A > C polymorphism on BP and aortic pulse wave velocity among M alays显示文摘Rehman A Rasool AH Naing L 2007Ann Hum Genet2007,71,1:1
14Long-term pancreas allograft outcome in simultaneous pancreas-kidney transplantation显示文摘Bloom RD Olivares M Rehman L 1997Transplantation1997,64,:1
15Assessment of crop damage by wildlife in Chunati Wilklife Sanctuary显示文摘MIAH M D REHMAN M L AHSAN M F 2001Balgladesh Tigerpaper2001,28,4:1
16Assessment ofcrop damage by wildlife in Chunati Wilklife Sanctuary 显示文摘MIAH M D REHMAN M L AHSAN M F 2001Balgladesh Tigerpaper2001,28,4:1
17Manufacturing configurationselection using multicriteria decision tool显示文摘REHMAN A U REHMAN L U 2013The International Journal of Advanced Manufacturing Technology2013,65,:1
18Characteristics of the novelinterleukin family biomarker ST2 in patients with acute heart failure显示文摘Rehman S U Mueller T Januzzi J L Jr 2008J Am Coll Cardiol2008,52,:1
19Diaphragmatic rupture: A complication of violent cough显示文摘George L Rehman SU Khan FA 2000Chest2000,117,4:1
20Duplex PCR assay for the detection of avian adeno virus and chicken anemia virus prevalent in Pakistan显示文摘Rehman L U Sultan B Ali I 2011Virol J2011,8,:1
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