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	题名	作者	年代	出处	被引量
1	Alpha-fetoprotein expression is a potential prognostic marker in hepatocellular carcinoma显示文摘AIM: To characterize the alpha-fetoprotein (AFP) positive and negative hepatocellular carcinoma (HCC) samples.METHODS: Thirty-seven paraffin-embedded human HCC samples were analyzed by immunohistochemistry for the following antigens: AFP, β-catenin, p53, CD44, MSH-2,MLH-1, and HNF-4. The tumors were divided into two groups based on the AFP expression. The immunophenotypic data and important clinical parameters were studied between the two groups.RESULTS: Twenty-one of the thirty-seven examined HCCs were AFP positive. Seven with nuclear p53 staining were AFP positive, while seven tumors with nuclear β-catenin staining were AFP negative. CD44 staining and high histological tumor grade were more frequent among the AFP-positive HCCs. The other immunophenotypical and dinical parameters did not show statistically significant difference in their distribution between the AFP positive and negative samples.CONCLUSION: AFP expression in HCC correlates with unfavorable prognostic factors, while nuclear β-catenin positivity is more common among the AFP-negative liver tumors. This observation supports the microarray data onin vivo human tumors.	Dénes Grg János Regly-Mérei Sándor Paku László Kopper Péter Nagy	2005	World Journal of Gastroenterology2005，11，32：	6
2	High performance tangential flow filtration 显示文摘	van Reis R Gadam S Frautschy L N	1997	Biotechnol Bioeng1997，56，：	1
3	Optimal location of control valves in pipe networks by genetic algorithm显示文摘	REIS L F R PORTO R M	1997	ASCE Journal of Water Resources Planning and Management1997，123，6：	1
4	Dexamethasone-loaded scaffolds prepared by supercritical-assisted phase inversion显示文摘	Duarte A R C Mano J F Reis R L	2009	Acta Biomaterialia2009，5，6：	1
5	Osteochondral defects: Present situation and tissue engineering approaehes显示文摘	MANO J F REIS R L	2007	Journal of Tissue Engineering and Regenerative Medicine2007，1，4：	1
6	Monetary Policy for Inattentive Economies显示文摘	Ball L N Gregory Mankiw Reis R	2005	Journal of Monetary Economics2005，，52：	1
7	Effects of somatotropin and substrates on patterns of liver me- tabolism in lactating dairy cattle 显示文摘	KNAPP J R FREETLY H C REIS B L	1992	Journal of Dairy Science1992，75，4：	1
8	Starch-based mi- crospheres produced by emulsion crosslinking with a potential media dependent responsive behavior to be used as drug delivery carriers显示文摘	Malafaya P B Stappers F Reis R L	2006	Journal of Materials Science : Materials in Medicine2006，17，4：	1
9	Optimal location of control valves in pipe networks by genetic algorithm显示文摘	Reis L F R Porto R M Chaudhry F H	1997	Water Resource Planning Management1997，123，6：	1
10	Bone plasticity in response to exercise is sex-dependent in rats显示文摘	VICENTE W S DOS REIS L M GRACIOLLI R G	2013	PLoS One2013，8，64：	1
11	Systematic analysis of longitudinal serological responses of pigs infected experimentally with African swine fever virus显示文摘	Reis A L Parkhouse R M Penedos A R	2007	J Gen Vir- ol2007，88，：	1
12	Immobilisation of catalase on the surface of biodegradable starch-based polymers as a way to change its surface characteristics 显示文摘	Costa S A Reis R L	2004	Journal of materials science Materials in medicine2004，15，4：	1
13	The biocompatibility of novel starch-based polymers and composites: in vitro studies 显示文摘	Marques A P Reis R L Hunt J A	2002	Biomaterials2002，23，：	1
14	Nature-inspired calcium phosphate coatings: present status and novel advances in the science of mimicry 显示文摘	OLIVEIRA A L MANO J F REIS R L	2003	Curr Opinion Solid Mater Sci2003，7，45：	1
15	Supercritical C02 extraction of γ-linolenie acid and other lipids from Arthrospira (Spirulina) maxima: Comparison with organic solvent extraction 显示文摘	Mendes R L Reis A D Palavra A F	2006	Food Chemistry2006，99，1：	1
16	Systematic anal- ysis of longitudinal serological responses of pigs infected experi- mentally with African swine fever virus 显示文摘	Reis A L Parkhouse R M Penedos A R	2007	J Gen Virol2007，88，9：	1
17	Smart thermoresponsive coatings and surfaces for tissue engineering: switching cell-material boundaries显示文摘	da Silva R M P Mano J F Reis R L	2007	Trends Bioteehn2007，25，12：	1
18	Bone tissue engineering: state of the art and future trends显示文摘	SALGADO A J COUTINHO O P REIS R L	2004	Macromol Biosci2004，4，：	1
19	Chemistry and applications of phosphorylated chitin and chitosan 显示文摘	Jayakumar R Reis R L Mano J F	2006	E-Polymers2006，35，3：	1
20	Dengue-2infection and the induction of apoptosis in hu-man primary monocytes显示文摘	Torrentes-Carvalho A Azeredo E L Reis S R	2009	Mem Inst Oswaldo Cruz Rio de Janeiro2009，104，8：	1

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