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10篇 您的检索式:作者名="Road L"
    题名 作者 年代 出处 被引量
1Light-directed Spatially addressable parallel chemical synthesis显示文摘Fodor S Road L Pirmung M 1991Science1991,251,3:1
2The determination of fluconazole in rodent diet using solid - phase extraction and high - performance liquid chromatography显示文摘Berridge J C Road L A 1987Journal of Pharmaceutical and Biomedical Analysis1987,5,5:1
3Pain in people with chronic obstructive pulmonary disease (COPD)显示文摘HajGhanbari B Holsti L Road JD 0,,:1
4Heart rate variability and precompetitive anxiety in swimmers显示文摘Cervantes Blasques JC Roads Font G Capdevila Ortis L 2009Psicothema2009,21,4:1
5Light-directed Spatially sddressable parallel chemical synthesis显示文摘Fodor S Road L Pirrung M 1991Science1991,251,:1
6Heart rate variability and precompetitive anxiety in swimmers显示文摘Cervantes Blasquez JC Roads Font G Capdevila Ortis L 0,,:1
7Cutaneous and pulmonary in-fections caused by mycobacterium vaccae显示文摘Hachem R Road L Rolston D V 1996Clin Infect Dis1996,23,1:1
8Metal readsorption and redistribution during the analytical fractionation of trace elements in oxic estuarine sediments显示文摘Comez Airza J L Girldez I Sanchez Roads D 1999Anal Chim Acta1999,399,:1
9Cloning, expression and characterization of human tissue-specific DNA polymerase λ2显示文摘DNA polymerase (POL) λ plays an important role during DNA repair and DNA nonhomologous recom-bination processes. A novel POL λ variant was cloned from a human liver cDNA library and named POL λ2 (GenBank Accession No. AY302442). POL λ2 has 2206 base pairs in length with an open reading frame of 1452 base pairs encoding a 482-amino-acids protein. Bioinformatics analysis reveals that POL λ2 spans 7.9 kb on human chromosome 10q24 and is composed of 8 exons and 7 introns. It has the specific domain of DNA polymerase X family-POL Xc at the C-terminus and BRCT domain at the N-terminus. POL λ2 was localized predominantly in nucleus in transfected L0-2 cells. It was expressed abundantly in liver and testis, weakly in ovary, and undetectably in other tested human tissues. In comparison with the expression ratio between POL λ and POL λ2 in normal liver tissues and hepato-cellular carcinoma (HCC) adjacent tissues, the ratio was aberrant in 80% of those 15 HCC specimens examined due to the up-regulated expression of POL λ. This abnormality might be involved in hepato-carcinogenesis. The recombinant POL λ2 with His-tag was expressed as a soluble active protein in E. coli BL21 (DE3)CONDON Plus and purified by Ni-NTA resin and then desalted by Superdex-75 chro-matography in an FPLC system. The analysis using isotope α-32P-dCTP incorporation in vitro showed that the purified recombinant POL λ2 exhibited DNA polymerase activity.GU Fu1, YOU Chun1, LIU JianPing1, CHEN Ao1,,YU Yao1, WANG Xiang1, WAN DaFang2, GU JianRen2, YUAN HanYing1, LI YuYang1 & Lü Hong1 1 State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai 200433, China 2 State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Shanghai 200032, China Present address: Food Inspection and Supervision Institute of Shanxi Province, No. 222 Changzhi Road, Taiyuan 030012, China 2007Science China(Life Sciences)2007,50,4:0
10Synthesis and Crystal Structure ofTrichlorotetrakis(tetrahydrofuran) Europium显示文摘Crystal of EuCl3(C4H8O4). was obtained from the reaction of C9H7Naand EuCl3,(0. 8: 1 mole ratio) in THF. It was crystallized in Fdd2 space group withunit cell parameters a=29. 161 (4), b=16. 558(6), c=9. 479 (3) A, V=4577 (4)A3, Z=8, Dc= 1.59 g/cm3, Mr=546. 75. F(000)=2192, A(Mo Ka) =0. 71069, u=31. 12 cm-1, T=293K. The final R and Rw values are 0. 040 and 0. 051 respective-ly. Three chlorine atoms and four oxygen atoms from THF are coordinated with cen-tral europium ion to form a pentagonal bipyramid polyhedron with coordination number7, the average Eu-Cl; bond length is 2. 637 A and Eu-O 2. 460A.KONG De-Yuan WANG Shao-Wu ZHU Qin XIE Yu-Yuan HUANG Xiao-Ying(Shanghai Institute of Materia Medica, the Chinese Academy of Sciences,Taiyuan road 294,Shanghai, 200031 ChinaDepartment of Chemistry, HongKong Chinese University, Shatin, HongkongState Key L 1998Chinese Journal of Structural Chemistry1998,17,1:0
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