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| 1 | The Genome of Medicinal Plant Macleaya cordata Provides New Insights into Benzylisoquinoline Alkaloids Metabolism显示文摘在动物农业和药的抗菌素的 overuse 引起了一系列潜在的威胁到公共健康。Macleaya cordata 是从 Papaveraceae 家庭的药用的植物种,提供为抗菌剂的制造的一个安全资源为家畜喂添加剂。从 M. 的活跃成分 ? cordata 被知道包括 benzylisoquinoline 碱(偏爱) 象 sanguinarine (圣) 和 chelerythrine (CHE ) 那样的 ?,而是他们的新陈代谢的小径还得在这非模型植物被学习。在 M. 的圣和 CHE 的活跃生合成 ? cordata 被喂 13标记 C 的酷氨酸。为了增加,推进卓见,我们 de novo 定序 M 的整个染色体。cordata,第一从 Papaveraceae 家庭被定序。M.? 盖住 378 Mb 的 cordata 染色体与 43.5%being 编码 22,328 预言的编码蛋白质的基因 transposable 元素。作为基础 eudicot 的一个成员, M.? cordata 染色体缺乏 ? 发生在几乎所有 eudicots 的 paleohexaploidy 事件。从 genomics 数据, 16 的一个完全的集合 ? 新陈代谢 ? 为圣和 CHE 生合成的基因被检索,并且 14 项他们的生物化学的活动被验证。这些 genomics 和新陈代谢的数据在 M. 显示出保存 BIA 新陈代谢的小径 ? cordata 并且由庄稼改进或微生物引起的小径重建为圣和 CHE 的未来生产提供知识基础。 | Xiubin Liu Yisong Liu Peng Huang Yongshuo Ma Zhixing Qing Qi Tang Huifen Cao Pi Cheng Yajie Zheng Zejun Yuan Yuan Zhou Jinfeng Liu Zhaoshan Tang Yixiu Zhuo Yancong Zhang Linlan Yu Jialu Huang Peng Yang Qiong Peng dinbo Zhang Wenkai Jiang Zhonghua Zhang Kui Lin Dae-Kyun Ro Xiaoya Chen Xingyao Xiong Yi Shang Sanwen Huang Jianguo Zeng | 2017 | Molecular Plant2017，10，7： | 19 |
| 2 | Developmentally Regulated Glucosylation of Bitter Triterpenoid in Cucumber by the UDP-Glucosyltransferase UGT73AM3显示文摘 | Yang Zhong Xiaofeng Xue Zhiqiang Liu Yongshuo Ma Kewu Zeng Lida Han Jingjing Qi Dae-Kyun Ro Soren Bak Sanwen Huang Yuan Zhou Yi Shang | 2017 | Molecular Plant2017，10，7： | 7 |
| 3 | The mitochondrial genome encodes abundant small noncoding RNAs显示文摘识别的小 noncoding RNA 都被原子染色体远因此编码。这里,我们主要报导鼠科、人的 mitochondrial 染色体编码几千小 noncoding RNA,它是源于 mitochondrial 基因(主人基因) 的感觉抄本,并且我们称为这些小 RNA mitochondrial 编码染色体的小 RNA (mitosRNAs ) 。影响的 DICER inactivation,但是完全没废除 mitosRNA 生产。MitosRNAs 看起来是当前未辩别出的 mitochondrial ribonucleases 的产品。提高的表示在 vitro 他们的主人基因铺平的 mitosRNAs 的 Overexpression,和 dysregulated mitosRNA 表示通常在 vivo 与异常 mitochondrial 基因表示被联系。我们的数据证明除了 37 已知的 mitochondrial 基因,哺乳动物的 mitochondrial 染色体也编码丰富的 mitosRNAs,它可以在房间在 mitochondrial 基因表示的控制起一个重要规章的作用。 | Seungil Ro Hsiu-Yen Ma Chanjae Park Nicole Ortogero Rui Song Grant W Hennig Huili Zheng Yung-Ming Lin2 Loredana Moro Jer-Tsong Hsieh wei Yant | 2013 | Cell Research2013，23，6： | 3 |
| 4 | Solvent-free fabrication of broadband WS2 photodetectors on paper显示文摘Paper-based devices have attracted extensive attention due to the growing demand for disposable flexible electronics.Herein,we integrate semiconducting devices on cellulose paper substrate through a simple abrasion technique that yields high-performance photodetectors.A solvent-free WS_(2) film deposited on paper favors an effective electron-hole separation and hampers recombination.The as-prepared paper-based WS2 photodetectors exhibit a sensitive photoresponse over a wide spectral range spanning from ultraviolet(365 nm)to near-infrared(940 nm).Their responsivity value reaches up to~270 mA W^(−1) at 35 V under a power density of 35 mW cm^(−2).A high performance photodetector was achieved by controlling the environmental exposure as the ambient oxygen molecules were found to decrease the photoresponse and stability of the WS_(2) photodetector.Furthermore,we have built a spectrometer using such a paperbased WS_(2) device as the photodetecting component to illustrate its potential application.The present work could promote the development of cost-effective disposable photodetection devices. | Wenliang Zhang Onur Çakıroğlu Abdullah Al-Enizi Ayman Nafady Xuetao Gan Xiaohua Ma Sruthi Kuriakose Yong Xie Andres Castellanos-Gomez | 2023 | Opto-Electronic Advances2023，6，3： | 2 |
| 5 | Unilateral facial paralysis oc- curring in an infant with enteroviral otitis media and aseptic meningitis 显示文摘 | Hostetler MA Suara RO Denison MR | 2002 | J Emerg Med2002，22，3： | 1 |
| 6 | Diabetic keratopathy显示文摘 | Schultz RO Van Horn DL Peters MA | | 0，，： | 1 |
| 7 | Purification and char- acterization of a liver microsomal cytochrome P450 isoenzyme with a high affinity and metabolic capacity for coumarin from pyrazole-treated D2 mice 显示文摘 | Juvonen RO Shkumatov VM Lang MA | 1988 | Eur J Biochem1988，171，12： | 1 |
| 8 | Unilateral facial paral-ysis occurring in an infant with enteroviralotitis media andaseptic meningitis显示文摘 | Hostetier MA Suara RO Denison MR | 2002 | J Emerg Mell2002，22，3： | 1 |
| 9 | Eosinophilic angiocentric fibrosis of sinonasal tract显示文摘 | Kosarac O Luna MA Ro JY | 2008 | Ann Diagn Pathol2008，12，4： | 1 |
| 10 | Dyslipidemia and the risk of incident hypertension in men显示文摘 | Halperin RO Sesso HD Ma J | 2006 | Hypertension2006，47，1： | 1 |
| 11 | Synthesis, characterization and targeting of biodegradable magnetic nanoeomposite particles by external magnetic fields显示文摘 | Asmatulu R Zalich MA Claus RO | 2005 | Journal of Magnetism and Magnetic Materials2005，292，3： | 1 |
| 12 | Diabetic keratopathy显示文摘 | Schultz RO Van Horn DL Peters MA | 1981 | Trans Am Ophthalmol Soc1981，79，： | 1 |
| 13 | Diabetic keratopathy显示文摘 | Sehultz RO Van Hom DL Peters MA | 1981 | Trans Am Opthalmol Soc1981，79，： | 1 |
| 14 | Oxidative stress in Alzheimer's disease显示文摘 | SMITH MA RO'Iq'KAMP CA NUNOMURA A | 2000 | Biochim Biophys Acta2000，1502，： | 1 |
| 15 | Resuscitation, anaesthesia and analgesia ot' the burned patient 显示文摘 | Berger MM Bernath MA Chiol~ro RL | 2001 | C~rr Opin Anaesthesiol2001，14，4： | 1 |
| 16 | Selective induction of coumarin 7-hydroxylase by pyrazole in D2 mice 显示文摘 | Juvonen RO Kaipainen PK Lang MA | 1985 | Eur J Bioch/FEBS1985，152，1： | 1 |
| 17 | Schwannoma of the urinary bladder:a case report显示文摘 | Cummings JM Wehry MA Parra RO | 1998 | Int J Urol1998，5，： | 1 |
| 18 | Durability of carotid endarterectomy显示文摘 | Eckey RO Pichelmann MA Meissner I | 2003 | Stroke2003，34，12： | 1 |
| 19 | Dyslipidemia and the risk of in- cident hypertension in men显示文摘 | Halperin RO Sesso HD Ma J | 2006 | Hypertension2006，47，1： | 1 |
| 20 | A biosocial model of the alcohol -aggression relationship显示文摘 | Pihl RO Peterson JB Lau MA | 1993 | J Stud Alcohol1993，11，： | 1 |
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