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| 1 | 分权、治理与民主显示文摘分权治理是近年来西方学界研究较多的一个问题。这里发表美国学者艾伦·罗森博姆的文章 ,该文解释了分权、治理、民主三个概念及其互动关系 ,论述了分权较之集权所具有的优点以及分权可能带来的局限性。文章代表了西方一部分学者的观点 ,供读者参考。 | 艾伦.罗森博姆(Allan Rosenbaum) 王诞庆 高秦伟 | 2001 | 国家行政学院学报2001，，4： | 11 |
| 2 | 长QT综合征复极化离散与早期后除极致心律失常机制的跨壁光学标测研究显示文摘目的 尖端扭转性室性心动过速 (室速 )是长QT综合征 (LQTS)的致命性心律失常 ,相关机制的细胞学水平研究还不十分清楚。本文报道对复极化离散和触发机制在尖端扭转性室速发生中的作用的研究结果。方法 动脉灌注的犬左心室楔形心肌块 ,经电压敏感性荧光染色后 ,行跨壁包括百余位点跨膜动作电位的同步光学标测研究。d 索他洛尔、海银花 (ATX Ⅱ)分别用来模拟LQT2和LQT3。对照组、LQT2组、LQT3组各 6块。结果 正常对照组的平均动作电位时限 (APD)为 (2 91± 2 7)ms,跨壁复极化的离散(DOR)为 (2 4± 6 )ms;LQT2组APD为 (35 6± 2 0 )ms,DOR为 (35± 9)ms,与对照组相比差异有显著性 (P <0 0 5 ) ;LQT3组APD为 (6 0 9± 92 )ms,DOR为 (12 1± 85 )ms,与对照组相比差异有显著性 (P <0 0 5 )。在LQT3组 ,早期后除极现象可见于所有类型的心肌细胞 ,但以心内膜和中层心肌细胞多见。触发活动常常起源于中层心肌细胞部位。结论 在LQT条件下 ,跨壁动作电位不均一地延长是导致复极化离散的重要原因 ,为心律失常的发生提供了基质。 | 刘金秋 杨延宗 Kenneth R Laurita David S Rosenbaum | 2004 | 中华心律失常学杂志2004，8，4： | 5 |
| 3 | QT间期延长综合征长短周期现象导致尖端扭转型室性心动过速的电生理机制的跨壁光学标测研究显示文摘 尖端扭转型室速是QT间期延长综合征患者晕厥和心源性猝死的主要原因,在尖端扭转型室速发生之前经常伴有心电图的长短周期现象,但是长短周期现象导致尖端扭转型室速的电生理机制目前还不清楚.…… | 刘金秋 杨延宗 Kenneth R. Laurita David S. Rosenbaum | 2004 | 中国心脏起搏与心电生理杂志2004，18，z1： | 2 |
| 4 | Pharmacologic weaking of extraocular muscles显示文摘 | Scott AB Rosenbaum A Collins CC | 1973 | Invest Ophthalmol Vis Sci1973，12，： | 2 |
| 5 | 高分辨率磁共振成像揭示巩膜扣带术后发生严重斜视的多重机制 | Wu T.- E.J. Rosenbaum A.L. Demer J.L. 陈立军 | 2005 | 世界核心医学期刊文摘(眼科学分册)2005，0，7： | 2 |
| 6 | The cognitive neuroscience of remote episodic, semantic and spatial memory显示文摘 | Morris Moscovitch Lynn Nadel Gordon Winocur Asaf Gilboa R Shayna Rosenbaum | 2006 | Current Opinion in Neurobiology2006，，2： | 2 |
| 7 | Electronic modulation of the T wave and cardiac memory显示文摘 | ROSENBAUM M R | 1982 | Am J Cardiol1982，50，2： | 2 |
| 8 | Liver myofibroblasts activate protein C and respond to activated protein C显示文摘AIM:To study the protein C activation system in human liver myofibroblasts,and the effects of activated protein C(APC)on these cells.METHODS:Human liver myofibroblasts were obtained by outgrowth.Expression of protease activated receptor 1(PAR-1),endothelial protein C receptor(EPCR) and thrombomodulin(TM)was analyzed by flow cytometry.Extracellular signal-regulated kinase(ERK)1/2 activation was assessed by Western blotting using anti-phospho-ERK antibodies.Collagen synthesis was studied with real-time reverse transcription-polymerase chain reaction(RT-PCR).Activation of protein C was studied by incubating liver myofibroblasts with zymogen protein C in the presence of thrombin and detecting the generation of APC with a colorimetric assay using a peptide substrate. RESULTS:Primary cultures of human liver myofibroblasts expressed EPCR on their surface,together with PAR-1 and TM.This receptor system was functional since exposure of myofibroblasts to APC inducedERK1/2 phosphorylation in a dose-and time-dependent manner.Furthermore,APC significantly upregulated the expression of collagen mRNA,as shown by real-time RT-PCR.Collagen upregulation was controlled through the ERK pathway as it was inhibited when using the mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor PD98059.Finally,using a cell-based colorimetric assay,we showed that intact myofibroblasts converted protein C into APC in the presence of thrombin.CONCLUSION:These data suggest that APC is a new modulator of liver myofibroblast activity and contributes to the pathophysiology of chronic liver diseases. | Jennifer Gillibert-Duplantier Anne Rullier Véronique Neaud Walter Kisiel Jean Rosenbaum | 2010 | World Journal of Gastroenterology2010，16，2： | 2 |
| 9 | Severe strabismus after scleral buckling: multiple mechanisms revealed by high-resolution magnetic resonance imaging显示文摘 | Wu TE Rosenbaum AL Demer JL | 2005 | Ophthalmology2005，112，2： | 1 |
| 10 | Cellular alternans:a mechanism linking calcium cycling proteins to cardiac arrhythmogenesis显示文摘 | WAN X ROSENBAUM DS | 2006 | Ann NYAcad Sci2006，1080，10： | 1 |
| 11 | Acute MRI changes in progressive ischemic stroke 显示文摘 | Kalowska E Rostrup E Rosenbaum S | 2008 | EUR Neurol2008，59，5： | 1 |
| 12 | Functional endoscopic sinus surgery显示文摘 | Kennedy DW Zinreich SJ Rosenbaum AE | 1985 | Arch Otolaryngol1985，111，： | 1 |
| 13 | Information learned from animal models of atrial fibrillation 显示文摘 | Finer JE Rosenbaum DS Donahue JK | 2009 | Cardiol Clin2009，27，1： | 1 |
| 14 | A report of the definition and classification of cerebral palsy显示文摘 | Rosenbaum P Paneth N Leviton A | 2007 | Dev Med Child Neurol2007，49，2： | 1 |
| 15 | Olmesartan medoxomil combined with hydrochlorothiazide improves 24-hour blood pressure control in moderate-to-severe hypertension显示文摘 | Rosenbaum D Girerd X | 2012 | Curr Med Res Opin2012，28，2： | 1 |
| 16 | A schedule for assessing self-control behaviors:Pre- liminary findings显示文摘 | Rosenbaum M | 1980 | Behavior Therapy1980，11，1： | 1 |
| 17 | Elder abuse education in primary care residency programs:a cluster group analysis elder abuse education in primary care residency programs:a cluster group analysis显示文摘 | Wagenaar D Rosenbaum R Herman S | | 0，，07： | 1 |
| 18 | 133-Adrenergic receptors mediate choroidal endothelial cell invasion, proliferation, and eel/ elongation 显示文摘 | Steinle JJ Zamora DO Rosenbaum JT | 2005 | Exp Eye Res2005，80，1： | 1 |
| 19 | A report: the definition and classification of cerebral palsy April 2006显示文摘 | Rosenbaum P Paneth N Levitun A | 2007 | Dev Med Child Neurol Suppl2007，109，： | 1 |
| 20 | Apoptosis in neurological disease显示文摘 | Savitz SI Rosenbaum DM | 1998 | Neurosurgery1998，42，3： | 1 |
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