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| 1 | An integrated approach for increasing breeding efficiency in apple and peach in Europe显示文摘Despite the availability of whole genome sequences of apple and peach,there has been a considerable gap between genomics and breeding.To bridge the gap,the European Union funded the FruitBreedomics project(March 2011 to August 2015)involving 28 research institutes and private companies.Three complementary approaches were pursued:(i)tool and software development,(ii)deciphering genetic control of main horticultural traits taking into account allelic diversity and(iii)developing plant materials,tools and methodologies for breeders.Decisive breakthroughs were made including the making available of ready-to-go DNA diagnostic tests for Marker Assisted Breeding,development of new,dense SNP arrays in apple and peach,new phenotypic methods for some complex traits,software for gene/QTL discovery on breeding germplasm via Pedigree Based Analysis(PBA).This resulted in the discovery of highly predictive molecular markers for traits of horticultural interest via PBA and via Genome Wide Association Studies(GWAS)on several European genebank collections.FruitBreedomics also developed pre-breeding plant materials in which multiple sources of resistance were pyramided and software that can support breeders in their selection activities.Through FruitBreedomics,significant progresses were made in the field of apple and peach breeding,genetics,genomics and bioinformatics of which advantage will be made by breeders,germplasm curators and scientists.A major part of the data collected during the project has been stored in the FruitBreedomics database and has been made available to the public.This review covers the scientific discoveries made in this major endeavour,and perspective in the apple and peach breeding and genomics in Europe and beyond. | Francois Laurens Maria JoséAranzana Pere Arus Daniele Bassi Marco Bink Joan Bonany Andrea Caprera Luca Corelli-Grappadelli Evelyne Costes Charles-Eric Durel Jehan-Baptiste Mauroux Hélène Muranty Nelson Nazzicari Thierry Pascal Andrea Patocchi Andreas Peil Bénédicte Quilot-Turion Laura Rossini Alessandra Stella Michela Troggio Riccardo Velasco Eric van de Weg | 2018 | Horticulture Research2018，5，1： | 10 |
| 2 | Fault-tolerant rate-mo-notonic first-fit in hard real-time scheduling systems显示文摘 | BERTOSSI A A MANCINI L V ROSSINI F | 1999 | IEEE Trans on Para Newland Distributed Systems1999，10，9： | 1 |
| 3 | Fault-tolerant rate- monotonic first fit scheduling in hard real-time systems 显示文摘 | Bertossi A Mancini L Rossini F | 1999 | IEEE Trans on Parallel and Distributed Systems1999，10，9： | 1 |
| 4 | Vitamin E improves thefree radical defense system potential and insulin sensitivity of rats fedhigh fructose diets显示文摘 | FAURE P ROSSINI E LAFOND J L | 1997 | Journal of Nutrition1997，127，1： | 1 |
| 5 | Force and torque analytical models of a reaction sphere actuator based on spherical harmonic rotation and decompo- sition显示文摘 | L Rossini | 2013 | Mechatronics [EEE/ASME Transactions on2013，18，3： | 1 |
| 6 | A symptom-specific analysis of the effect of high-frequency left or low-frequency right transeranial magnetic stimulation over the dorsolateral prefrontal cortex in major depression显示文摘 | ROSSINI D LUCCA A MAGRI L | 2010 | Neuropsychobiology2010，62，2： | 1 |
| 7 | Safety profile of recombinant canarypox HIV vaccines 显示文摘 | de Bruyn G Rossini A J Chiu Y L | 2004 | Vaccine2004，22，56： | 1 |
| 8 | Does rTMS hasten the response to escitalopram, sertraline, or venlafaxine in pa- tients with major depressive disorder? A double-blind, randomized,sham-controlled trial 显示文摘 | Rossini D Magri L Lucca A | 2005 | J Clin Psychiatry2005，66，12： | 1 |
| 9 | Characteristics and outcomes of patients with st-segment elevation myocardial infarction excluded from the harmonizing outcomes with re- vascularization and stents in acute myocardial infarction (HORIZONS-AMI) trial显示文摘 | Fiocca L Guagliumi G Rossini R | 2013 | Am J Cardiol2013，111，2： | 1 |
| 10 | Involvement of aryl hydrocarbon receptor signaling in the development of small cell lung cancer induced by HPV E6/E7 oncoproteins 显示文摘 | Buonomo T Carraresi L Rossini M | 2011 | Journal of translational medicine2011，9，1： | 1 |
| 11 | Alachlor regulation of corn glntathione s- transferases genes显示文摘 | Rossini L Frova C Mario Enrico Pe etal | 1998 | Pestic Biochemisiry and Physiol1998，60，： | 1 |
| 12 | The waning of teriparatide effect on bone formation markers in postmenopausal osteoporosis is associated with increasing serum levels of DKK1显示文摘 | Gatti D Viapiana O Idolazzi L Fracassi E Rossini M Adami S | | 0，，： | 1 |
| 13 | Relevance of endoscopic ultra-sound in the management of esophagus cancer therapy显示文摘 | Assef M Rossini L Rossini L | 2014 | Endosc Ultrasound2014，3，1： | 1 |
| 14 | Does HMS hasten the re- sponse to escitalopram, sertraline or venlafaxine in patients with major depressive disorder: A double blind, randomized, controlled trial显示文摘 | Rossini D Magri L lucca A | 2005 | J clin Paychiatry2005，66，： | 1 |
| 15 | Does rTMS hasten the response to escitalopram,sertraline,or venlafaxine in patients with major depressive disorder? A double-blind,randomized,sham-controlled trial显示文摘 | Rossini D Magri L Lucca A | 2005 | J Clin Psychiatry2005，66，12： | 1 |
| 16 | Immunophenotypic features of acute myeloid leukemias over expressing theinterleukin 3receptor alpha chain显示文摘 | Riccioni R Rossini A Calabro L | 2004 | Leuk Lymphoma2004，45，8： | 1 |
| 17 | Fault-Tolerant Rate-Monotonic First-Fit Scheduling in Hard-Real-Time Systems显示文摘 | Bertossi A A Mancini L V Rossini F | 1999 | IEEE Trans Paralled and Distributed Systems1999，10，9： | 1 |
| 18 | Intravenous neridronate in children with osteogenesis imperfecta: a randomized controlled studyr显示文摘 | Gatti D Antoniazzi F Prizzi R Braga V Rossini M Tat6 L | 2005 | J Bone Miner Res2005，20，： | 1 |
| 19 | Fire risk management system for safe operation of large atmospheric storage tanks显示文摘 | Crippa C Fiorentini L Rossini V | 2009 | Journal of Loss Prevention in the Process Industries2009，22，5： | 1 |
| 20 | Clinical development of neridronate: potential for new applications显示文摘 | Gatti D Rossini M Viapiana O Idolazzi L Adami S | 2013 | Ther Clin Risk Manag2013，9，： | 1 |
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