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| 1 | Non-alcoholic fatty liver disease may not be a severe disease at presentation among Asian Indians显示文摘瞄准:与非含酒精的脂肝疾病(NAFLD ) 评估病人的临床、生物化学的侧面并且在表示估计他们的组织学的严厉。方法:介绍给所有印度的肝诊所的连续病人与提起的 transaminases 医学科学(AIIMS ) 开创到乘正常的上面的限制的至少 1.5,并且组织学地证实的非酒精的脂肝疾病被包括。或谁有重要白酒吸入或另外的肝疾病的积极标记的病人正在服知道生产脂肝的药被排除。这个组的临床、生物化学、组织学的侧面被学习。结果:有 NAFLD 的 51 个病人形成了学习人口。他们的中部的年龄和 BMI 是 34 (17-58 ) 年并且 26.7 (21.3-32.5 ) kg/m (2 ) 分别地并且(90.1%) 46 是男性。病人的多数有温和发炎,也分级 1 [32 (63%)] 或等级 2 [16 (31%)] 并且仅仅 3 (6%) 病人们有严重(等级 3 ) 发炎。23 (45%) , 19 (37%) , 8 (16%) 并且 1 (2%) 病人有 0, 1, 2 和 3 纤维变性分别地在索引活体检视和没有上有的舞台肝硬化。在 univariate 分析上,甘油三酸酯铺平超过 150 mg %( 或 = 7.1;95% CI:1.6-31.5, P = 0.002 ) 并且著名计算机生产厂商 / 中高音 ratio>1 (或 = 14.3;95% CI:1.4-678.5, P = 0.008 ) 与发炎的高等级被联系,任何一个都没与先进纤维变性被联系。在上多变量逻辑回归分析, hypertriglyceridemia >150 mg% 是独立地与发炎的高等级的存在联系的唯一的因素(或 = 1.6;95% CI:1.3-22.7, P = 0.02 ) ,当任何一个都没与先进纤维变性被联系时。甘油三酸酯层次与煽动性的等级断然相关(r = 0.412;P = 0.003 ) 。结论:在诺思印第安人病人的 NAFLD 是年轻超重男性,其中大多数是抵抗的胰岛素的疾病,他们趋于在表示有温和组织学的疾病。 | Kaushal Madan Yogesh Batra S Datta Gupta Bal Chander K D Anand Rajan M S Tewatia S K Panda S K Acharya | 2006 | World Journal of Gastroenterology2006，12，21： | 7 |
| 2 | Plasma cathepsin L:A prognostic marker for pancreatic cancer显示文摘AIM:To assess the prognostic significance of cathepsin L,a cysteine protease that degrades the peri-tumoral tissue,in patients with pancreatic cancer.METHODS:Plasma samples from 127 pancreatic cancer patients were analyzed for cathepsin L levels by ELISA.Out of these patients,25 underwent surgeryand their paraffin-embedded tissue was analyzed for cathepsin L expression by immunohistochemistry.Survival of patients and clinicopathological parameters was correlated with cathepsin L expression in plasma and tissue using appropriate statistical analysis.RESULTS:The mean(±SD)cathepsin L in plasma samples of pancreatic cancer patients was 5.98±2.5ng/m L that was significantly higher compared to the levels in healthy controls(3.83±0.45)or chronic pancreatitis patients(3.97±1.06).Using ROC curve,a cut-off level of 5.0 ng/m L was decided for survival analysis.Elevated plasma levels of cathepsin L were found to be associated with poor prognosis(P=0.01)in multivariate analysis.The plasma levels of the protease decreased after surgery.Though no significant correlation was seen between plasma and tissue expression of this protease,a trend did emerge that high cathepsin L expression in tissue correlated with its high levels in plasma.CONCLUSION:Cathepsin L levels in plasma of pancreatic cancer patients may be used as a potential prognostic marker for the disease. | Nidhi Singh Prasenjit Das Surabhi Gupta Vikas Sachdev Siddhartha Srivasatava Siddhartha Datta Gupta Ravindra Mohan Pandey Peush Sahni Shyam S Chauhan Anoop Saraya | 2014 | World Journal of Gastroenterology2014，20，46： | 2 |
| 3 | Effect of cyclosporine on fertility in male rats显示文摘 | Srinivas M Agarwala S Datta Gupta S | 1998 | Pediatr Surg Int1998，13，56： | 1 |
| 4 | Inhibitor of apoptosis proteins are substrates for the mitochondrial serine protease Omi/HtrA2显示文摘 | Srinivasula SM Gupta S Datta P | 2003 | J Biol Chem2003，278，31： | 1 |
| 5 | Varietal identifi- cation and assessment of genetic relationships in Hippeastrum using RAPD markers 显示文摘 | CHAKRABARTY D GUPTA V N DATTA S K | 2007 | Plant Bioteehnology Reports2007，1，： | 1 |
| 6 | Studies on the efficacy of a phytohormone producing pliospliate solubiliz-ing Bacillus subtilis in augmenting paddy yield in acid soils of N-agaland显示文摘 | Gupta R K Datta M Banik S | 2000 | Plant and Soil2000，89，： | 1 |
| 7 | Vaginal angiomyofib roblastoma显示文摘 | Banerjee K Datta Gupta S Mathur SR | 2004 | Arth Gynecol Obsbet2004，270，2： | 1 |
| 8 | Studies on the efficacy of a phytohormone producing phosphate solubilizing Bacillus firmus in augmenting paddy yield in acid soils of Nagaland显示文摘 | Datta M Banik S Gupta R K | 1982 | Plant and Soil1982，，69： | 1 |
| 9 | Studies on the efficacy of a phyto- hormone producing phosphate - solubilizing Bacillus firmus in augmenting paddy yield in acid soils of Nagaland 显示文摘 | Datta M Banik S Gupta R | 1982 | Plant and Soil1982，69，3： | 1 |
| 10 | Electrode kinetics of ethanol oxidation on novel CuNi alloy supported catalysts synthesized from PTFE suspension 显示文摘 | Gupta S S Datta J | 2005 | J Power Sources2005，145，2： | 1 |
| 11 | Streamline - based production data Integration into high resolution reservoir models 显示文摘 | Datta - Gupta A Yoon S Barman I | 1998 | JPT1998，50，12： | 1 |
| 12 | Inhibitor of apoptosis proteins are substrates for the mitochondrial serine protease Omi/HtrA2 显示文摘 | Srinivasula SM Gupta S Datta P | 2003 | J Biolo Chem2003，278，31： | 1 |
| 13 | Phenotypic method for differentiation of carbapenemases in enterobacteriaceae: study from north India显示文摘 | Datta P Gupta V Garg S | 2012 | Indian J Pathol Microbiol2012，55，3： | 1 |
| 14 | Inhibitor of apoptosis proteins are substrates for the mitochondrial serine protease Omi/HtrA2显示文摘 | Srinivasula S M Gupta S Datta P | 2003 | J Biol Chem2003，278，31： | 1 |
| 15 | Studies on the efficacy of a phytohormone producing phosphate solubilizing Bacillus firmus in augmenting paddy yield in acid soils of Nagaland显示文摘 | Datta M Banik S Gupta R K | 1982 | Plant and Soil1982，69，3： | 1 |
| 16 | Vaginal angiomyo fibroblaskma显示文摘 | Bamerjee K Datta Gupta S Mathur SR | 2004 | Arch Gynecolobstel2004，270，： | 1 |
| 17 | Multiscale data inte gration using Markov random fields显示文摘 | Lee S H Malallah A Datta Gupta A | 2002 | SPE Reservoir Evaluation and Engineering2002，5，： | 1 |
| 18 | Regulation of chemokine mRNA stability by lipopolysaccharide and IL-10显示文摘 | Biswas R Datta S Das Gupta J | 2003 | J Immunol2003，170，12： | 1 |
| 19 | The C-terminal tail of presenilin regulates Omi/HtrA2 protease activity显示文摘 | Gupta S Singh R Datta P | 2004 | J Biol Chem2004，279，45： | 1 |
| 20 | Antioxidant enzyme activities during in vitro morphogenesis of gladiolus and the effect of application of antioxidant on plant regeneration显示文摘 | Gupta S D Datta S | 2003 | Biol Plant2003，47，： | 1 |
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