|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Elevated basal intestinal mucosal cytokine levels in asymptomatic first-degree relatives of patients with Crohn's disease显示文摘AIM To determine levels of cytokines incolonic mucosa of asymptomatic first degreerelatives of Crohn’s disease patients.METHODS Cytokines(Interleukin(IL)1-Beta,IL-2,IL-5 and IL-8)were measured using ELISAin biopsy samples of normal looking colonicmucosa of first degree relatives of Crohn’sdisease patients(n = 9)and from normalcontrols(n = 10)with no family history ofCrohn’s disease.RESULTS Asymptomatic first degree relativesof patients with Crohn’s disease had significantlyhigher levels of basal intestinal mucosalcytokines(IL-2,IL-5 and IL-8)than normalcontrols.Whether these increased cytokinelevels serve as phenotypic markers for a geneticpredisposition to developing Crohns diseaselater on,or whether they indicate early(pre-clinical)damage has yet to be further defined.CONCLUSION Asymptomatic first degreerelatives of Crohn’s disease patients have higherlevels of cytokines in their normal-lookingintestinal mucosa compared to normal controls,This supports the hypothesis that increasedcytokines may be a cause or an early event inthe inflammatory cascade of Crohns disease andare not merely a result of the inflammatoryprocess. | Indaram AVK Nandi S Weissman S Lam S Bailey B Blumstein M Greenberg R Bank S | 2000 | World Journal of Gastroenterology2000，6，1： | 8 |
| 2 | Formation of trace by-products in the premixed flames of CH3Cl - C2H4 显示文摘 | Weissman M Benson S W | 1983 | J Phys Chem1983，87，2： | 1 |
| 3 | Oxidative protein folding in eukaryotes:mechanisms and consequences显示文摘 | Tu B P Weissman J S | 2004 | J Cell Biol2004，164，： | 1 |
| 4 | Intramolecular energy transfer the fluores- cence of comples of europium 显示文摘 | Weissman S I | 1942 | J Chem Phys1942，10，4： | 1 |
| 5 | Titania-zirconia mixed oxide aerogels as supports for hydrotreating catalysts 显示文摘 | Weissman J G Ko E I Kaytal S | 1993 | Applied Catalysis A : General1993，94，1： | 1 |
| 6 | Supporting mobile database access through query by icons显示文摘 | A Massari S Weissman P K Chrysanthis | 1996 | International Journal of Distributed and Parallel Databases1996，4，3： | 1 |
| 7 | Ubiquitin char- ging of human class III ubqintin-conjugating enzymes triggers their nuclear import 显示文摘 | Plaiker S M Plafker K S Weissman A M | 2004 | Journal of Cell Biology2004，167，4： | 1 |
| 8 | The first probabilistic track of the international planning competition 显示文摘 | Younes H L S Littman M L Weissman D | 2005 | Journal of Artificial Intelligence Research2005，24，1： | 1 |
| 9 | SINAT5 promotes ubiquitin-related degradation of NAC1 to attenuate auxin signals显示文摘 | XIE Q GUO H S DALLMAN G FANG SH Y WEISSMAN A M CHUA N H | 2002 | Nature2002，419，： | 1 |
| 10 | Dif- ferential stability and trade-off effects of pathoadaptive mu- tations in the Escherichia coli FimH adhesin 显示文摘 | Weissman S J Beskhlebnaya V Chesnokova V | 2007 | Infection and immunity2007，75，7： | 1 |
| 11 | Fetal pleural effusion: the risk of fetal trisomy 显示文摘 | Achiron R Weissman A Lipitz S | 1995 | Gynecol Obstet Invest1995，39，3： | 1 |
| 12 | Hematopoietic stem and progenitor cells: clinical and preclinical regeneration of the hematolymphoid system显示文摘 | Shizuru J A Negrin R S Weissman I L | 2005 | Annu Rev Med2005，56，1： | 1 |
| 13 | Stem cells, cancer, and cancer stem cells显示文摘 | Reya T Morrison S J Clarke MF Weissman IL | 2001 | Nature2001，414，6859： | 1 |
| 14 | Construction of libraries enriched for sequence repeats and jumping clones , and hybridization selection for region specific markers显示文摘 | Kandpal R P Kandpal G Weissman S M | 1994 | Proc Natl Acid Sci USA1994，91，： | 1 |
| 15 | Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2显示文摘 | Vaux D L Weissman I L Kim S K | 1992 | Science1992，258，5059： | 1 |
| 16 | Decay of endoplasmic reticu- lum-localized mRNAs during the unfolded protein response显示文摘 | Hollien J Weissman J S | 2006 | Science2006，313，5783： | 1 |
| 17 | Stem cells, cancer, and cancer stem cells显示文摘 | Reya T Morrison S J Clarke M F Weissman I L | 2001 | Nature2001，414，： | 1 |
| 18 | Journal of Colloid and Interface Science 显示文摘 | Reese C E Guerrero C D Weissman J M Lee K Asher S A | 2000 | 232(1): 762000，232，1： | 1 |
| 19 | Construction of libraries enriched for sequence repeats and jumping clones,and hybridization selection for region-specific markers显示文摘 | Kandpal R Kandpal G Weissman S M | 1994 | Proc Natl Acad Sci USA1994，91，： | 1 |
| 20 | Pigmented vitlonodular synovitis 显示文摘 | Bravo S M Winalski C S Weissman B N | 1996 | Radiol Clin North Am1996，34，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员