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| 1 | Acute renal failure requiring dialysis after percutaneous coronary interventions显示文摘 | LuisGruberg RoxanaMehran GeorgeDangas Gary S.Mintz RonWaksman Kenneth M.Kent Augusto D.Pichard Lowell F.Satler HongshengWu Martin B.Leon | 2001 | Cathet Cardiovasc Intervent2001,,4: | 1 |
| 2 | Intravascular ultrasound assessment of the incidence and predictors of edge dissections and intramural hematomas after drug-eluting stent implantation显示文摘Objective We used intravascular ultrasound (IVUS) to assess incidence, predictors, morphology, and angiographic findings of edge dissections and intramural hematomas after drug-eluting stent (DES) implantation. Methods We studied 887 patients with 1 045 non-in-stent restenosis lesions in 977 native arteries undergoing DES implantation with IVUS imaging, and compared the dissected stent end to the non-dissected stent end. Results Eighty-two dissections were detected; 51.2% (42/82) involved the proximal and 48.8% (40/82) the distal stent edge. When compared to the non-dissected stent end, residual plaque area [(8.0±4.3) mm2 vs (5.2±3.0) mm2, P<0.01], plaque burden [(52±12)% vs (36±15)%, P<0.01], plaque eccentricity (8.4±5.5 vs 4.0±3.4, P<0.01), and stent edge symmetry (1.17±0.11 vs 1.14±0.08, P=0.02) were larger; plaque burden≥50% was more frequent (62% vs 17%, P<0.01) and calcium deposits (52.5% vs 35.6%, P=0.03) more common; and the lumen/stent area (0.86±0.16 vs 1.02±0.18, P<0.01) was smaller in the stent dissected end. Independent predictors of stent edge dissection were residual plaque eccentricity (OR=1.3, P<0.01) and residual plaque burden≥50% (OR=7.3, P<0.01). Intramural hematomas occurred in 34.1% (28/82) of dissections.Independent predictors of intramural hematomas were plaque eccentricity (OR=1.4, P=0.005), plaque burden≥50% (OR=7.1, P=0.02), and mean lumen diameter to stent diameter ratio (OR=0.37, P=0.04).Concluslon IVUS identified edge dissections after 9.4% of DES implantations. Residual plaque eccentricity and significant plaque burden predicted coronary stent edge dissections. Dissections in less diseased reference segments with an arc of normal vessel wall (greater plaque eccentricity) more often evolved into an intramural hematoma. | Gary S.Mintz Stéphane G.Carlier Jose de Ribamar Costa Jr Koichi Sano Joanna Lui Giora Weisz Issam Moussa George D.Dangas Roxana Mehran Edward M.Kreps Michael Collins Gregg W.Stone Jeffrey W.Moses GE Junbo Martin B.Leon | 2007 | 上海医学2007,30,S1: | 0 |
| 3 | Sirolimus-eluting stent fractures associated with aneurysm and very late stent thrombosis in the right coronary artery显示文摘 Although the occurrence of coronary stent fracture is rare,recent reports showed that stent fracture after sirolimus-eluting stent(SES)implantation may be associated with neointimal hyperplasia and restenosis.We report two cases of stent fracture that occurred late after elective SES implantation into the right coronary artery(RCA)that were related to the aneurysm,restenosis,thrombosis,and vessel occlusion.…… | Gary S.Mintz Stéphane G.Carlier Martin B.Leon | 2007 | 上海医学2007,30,z1: | 0 |
| 4 | Assessment of inconclusive left main coronary lesions: lessons from an intravascular ultrasound study显示文摘Objective Angiographic assessment of a left main coronary artery (LMCA) stenosis is often difficult and unreliable. Intravascular ultrasound (IVUS) assessment of absolute lumen dimensions has been shown to correlate with fractional flow reserve (FFR) and to predict clinical outcome in patients with a LMCA stenosis. Methods During 21 months period (October, 2004 to July, 2006), 153 patients (Ostial lesions, n=47; Non-ostial lesion, n=106) underwent IVUS evaluation specifically to assess the severity of an angiographically inconclusive LMCA narrowing. IVUS analysis included plaque morphology; external elastic membrane (EEM), lumen, plaque cross-sectional areas (CSA), plaque burden (plaque CSA/ EEM) and remodeling index (lesion EEM CSA/reference EEM CSA). Results Overall, minimum lumen area (MLA) and diameter (MLD) and plaque burden measured 8.2 mm2, 2.6 mm, and 59.3 %, respectively. An MLA<6.0 mm2 (which has been shown to correlate with a FFR <0.75) was seen 41.5% in ostial lesions and 44.5% in non-ostial lesions. In particular, ostial LMCA lesions had a larger MLA and a smaller plaque burden than non-ostial lesions (Table). Conclusions Patients referred for LMCA evaluation commonly have insignificant narrowing. Negative remodeling was prominent at the LMCA ostium. These patients deserve IVUS assessment before revascularization. | Gary S.Mintz Stéphane G.Carlier Jose de Ribamar Costa Jr Koichi Sano Joanna Lui Giora Weisz Issam Moussa George D.Dangas Roxana Mehran Edward M.Kreps Michael Collins Gregg W.Stone Jeffrey W.Moses Junbo Ge Martin B.Leon | 2007 | 上海医学2007,30,S1: | 0 |
| 5 | ^(192)Ir射线治疗老年冠脉支架内再狭窄的机制和1年临床随访:系列血管内超声分析显示文摘目的 探讨1 92 Ir对老年冠心病支架内再狭窄的 1年的临床疗效及机制。方法 99例老年冠心病支架内再狭窄病人经常规介入治疗后随机分为1 92 Ir治疗组和安慰剂组 ,在放疗后即刻和 6个月行血管内超声检查 ,分别测量支架、管腔及增生内膜的内径和面积 ,并临床随访 1年 ,对所得参数进行统计学处理。结果 99例病人中 ,糖尿病 3 9.4%,有支架内再狭窄史 5 8.6%,弥漫性病变 68%,静脉桥病变 18.5 %;两组治疗前后及两组间支架内径和面积无显著性变化 ,两组间放疗后即刻各参数也无显著性变化。随访中 ,治疗组和安慰剂组的最小腔内径、最小腔内面积和平均腔内面积分别为 :2 .0 3± 0 .47与 1.5 9± 0 .65mm ,P <0 .0 0 1;4.3 0± 2 .0 0与 2 .81± 2 .5 6mm2 ,P =0 .0 0 6;6.47± 2 .5 3与 5 .0 3± 3 .82mm2 ,P =0 .0 94。治疗组与对照组平均新生内膜和新生内膜百分比分别为 2 .2 2± 1.2 6与 3 .3 7± 1.89,P =0 .0 11;3 5± 17%与 5 7± 2 3 %,P <0 .0 0 1。 6个月的再狭窄率 ,治疗组与对照组分别为 :2 4.71%与 78.6%,p <0 .0 1。临床随访 1年 ,治疗组与对照组主要的心脏事件、靶血管及靶病变再介入治疗分别为 73 .0 %与 48.6%,P =0 .0 2 7;2 3 .8%与 5 1.4%,P =0 .0 0 6;11.6%与 40 .97%,P =0 .0 0 7。结论? | 吴智勇 Gary S.Mintz | 2003 | 海南医学2003,14,12: | 0 |
| 6 | 血管内超声部分研究进展显示文摘1 对冠状动脉粥样硬化及再狭窄的认识 Glagov及其同事在病理方面的研究表明,在动脉粥样硬化早期阶段,冠状动脉的正性重构(一种增加动脉面积的病理变化过程)起到了维持动脉内径的作用。这就解释了为何血管内超声(intravascular ul-trasound,IVUS)在冠心病病人“动脉造影正常” | Ultrasound Gary S.Mintz 李越 王青 | 2000 | 当代医学2000,6,7: | 0 |
| 7 | Volumetric intravascular ultrasound comparisons of drug-eluting stent thrombosis and in-stent restenosis显示文摘Objectives We compared intravascular ultrasound (IVUS) findings of drug-eluting stent (DES)-treated lesions that developed stent thrombosis versus in-stent restenosis (ISR) to identify underlying mechanical differences. Methods IVUS findings in 15 post-DES thrombosis patients were compared with 45 matched ISR patients who had no evidence of stent thrombosis. Results Minimum stent area [MSA, (3.7±0.8) mm2 vs (4.9±1.8) mm2, P=0.01], minimum stent diameter [(1.9±0.3) mm vs (2.3±0.4) mm, P=0.005], mean stent area [(5.2±0.8) mm2 vs (7.2±2.1) mm2, P<0.01], and both focal [MSA/reference lumen area, (54.7±15.9)% vs (75.0±20.1)%, P=0.001] and diffuse stent expansion [mean stent area/reference lumen area, (76.6±23.0)% vs (110.3±23.3)%, P<0.01] were significantly smaller in the stent thrombosis group (vs the ISR group). An MSA <4.0 mm2 (73.3% vs 35.6%, P=0.01) or <5.0 mm2 (86.7% vs 53.3%, P=0.02) was more often found in the stent thrombosis group (vs the ISR group). The MSA site occurred more frequently in the proximal stent segment within the stent thrombosis group compared to the ISR group (60% vs 24.4%, P=0.01). There were no differences in edge dissection, stent fracture, or stent-vessel wall malapposition between the two groups. Independent predictors of stent thrombosis were diffuse stent expansion (OR=1.5, P=0.03) and proximal location of the MSA site (OR=12.7, P=0.04). Conclusion DES-treated lesions that develop thrombosis or restenosis are often underexpanded. Underexpansion appears to be more severe in DES-thrombosis lesions. Lesions with diffuse underexpansion and a proximal (vs distal) underexpanded MSA site are more predisposed to thrombus formation than ISR. | Gary S.Mintz Stéphane G.Carlier Jose de Ribamar Costa Jr Koichi Sano Joanna Lui Giora Weisz Issam Moussa George D.Dangas Roxana Mehran Edward M.Kreps Michael Collins Gregg W.Stone Jeffrey W.Moses GE Junbo Martin B.Leon | 2007 | 上海医学2007,30,S1: | 0 |
| 8 | Sirolimus-eluting stent fractures associated with aneurysm and very late stent thrombosis in the right coronary artery显示文摘Although the occurrence of coronary stent fracture is rare, recent reports showed that stent fracture after sirolimus-eluting stent (SES) implantation may be associated with neointimal hyperplasia and restenosis. We report two cases of stent fracture that occurred late after elective SES implantation into the right coronary artery (RCA) that were related to the aneurysm, restenosis, thrombosis, and vessel occlusion. | LIU Xuebo Gary S.Mintz Stéphane G.Carlier Martin B.Leon | 2007 | 上海医学2007,30,S1: | 0 |