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| 1 | Operative complications and economic outcomes of cholecystectomy for acute cholecystitis显示文摘BACKGROUND Recent management of acute cholecystitis favors same admission(SA)or emergent cholecystectomy based on overall shorter hospital stay and therefore cost savings.We adopted the practice of SA cholecystectomy for the treatment of acute cholecystitis at our tertiary care center and wanted to evaluate the economic benefit of this practice.We hypothesized that the existence of complications,particularly among patients with a higher degree of disease severity,during SA cholecystectomy could negate the cost savings.AIM To compare complication rates and hospital costs between SA vs delayed cholecystectomy among patients admitted emergently for acute cholecystitis.METHODS Under an IRB-approved protocol,complications and charges for were obtained for SA,later after conservative management(Delayed),or elective cholecystectomies over an 8.5-year period.Patients were identified using the acute care surgery registry and billing database.Data was retrieved via EMR,operative logs,and Revenue Cycle Operations.The severity of acute cholecystitis was graded according to the Tokyo Guidelines.TG18 categorizes acute cholecystitis by Grades 1,2,and 3 representing mild,moderate,and severe,respectively.Comparisons were analyzed withχ2,Fisher’s exact test,ANOVA,ttests,and logistic regression;significance was set at P<0.05.RESULTS Four hundred eighty-six(87.7%)underwent a SA while 68 patients(12.3%)received Delayed cholecystectomy.Complication rates were increased after SA compared to Delayed cholecystectomy(18.5%vs 4.4%,P=0.004).The complication rates of patients undergoing delayed cholecystectomy was similar to the rate for elective cholecystectomy(7.4%,P=0.35).Mortality rates were 0.6%vs 0%for SA vs Delayed.Patients with moderate disease(Tokyo 2)suffered more complications among SA while none who were delayed experienced a complication(16.1%vs 0.0%,P<0.001).Total hospital charges for SA cholecystectomy were increased compared to a Delayed approach($44500±$59000 vs$35300±$16700,P=0.019).The relative risk of developing a complication was 4.2x[95%confidence interval(CI):1.4-12.9]in the SA vs Delayed groups.Among eight patients(95%CI:5.0-12.3)with acute cholecystitis undergoing SA cholecystectomy,one patient will suffer a complication.CONCLUSION Patients with Tokyo Grade 2 acute cholecystitis had more complications and increased hospital charges when undergoing SA cholecystectomy.This data supports a selective approach to SA cholecystectomy for acute cholecystitis. | Christopher P Rice Krishnamurthy B Vaishnavi Celia Chao Daniel Jupiter August B Schaeffer Whitney R Jenson Lance W Griffin William J Mileski | 2019 | World Journal of Gastroenterology2019,25,48: | 8 |
| 2 | Body traits in rainbow trout: II Estimates of heritability and of phenotypic and genetic correlations显示文摘 | Schaeffer L R | 1989 | Aquaculture1989,80,: | 1 |
| 3 | Demographic and clinical characteristics of men with chronic prostatitis:the national institutes of health chronic prostatitis cohort study显示文摘 | Schaeffer A J Landis J R Knauss | 2002 | J Urol2002,168,: | 1 |
| 4 | The Embodiment of Carbon Associated with Brazilian Imports and Exports显示文摘 | Schaeffer R Sa' AL | 1996 | Energy Conversion and Management1996,37,68: | 1 |
| 5 | Use of test day yields for genetic evaluation of dairy sires and cows 显示文摘 | Ptak E L R Schaeffer | 1993 | Livest Prod Sci1993,34,: | 1 |
| 6 | On symmetric solutions of the relativistic Vlasov- Poisson system 显示文摘 | Glassey R T Schaeffer J | 1985 | Comm Math Phys1985,101,: | 1 |
| 7 | Potential for reduction of CO2 emissions and a low-carbon scenario for the Brazilian industrial sector显示文摘 | Henriques J M FDantas F Schaeffer R | | 0,,04: | 1 |
| 8 | Energy and CarbonEmbodied in the International Trade of Brazil:An Input - Output Approach显示文摘 | Machado G Schaeffer R Worrell E | 2001 | Ecological Economics2001,39,3: | 1 |
| 9 | Prevention of bronchopulmonary dysplasia by administration of bovine superoxide dismutase in preterm infants with respiratory distress syndrome显示文摘 | Evans H Concepcion L Jhaveri R Schaeffer H Friedman A | 1984 | J Pediatr1984,105,78: | 1 |
| 10 | Estimates of genetic parameters for a test day model with random regressions for yield traits of first lactation Holsteins显示文摘 | Jamrozik J Schaeffer L R | 1997 | Journal of Dairy Science1997,80,: | 1 |
| 11 | PGC-1a coactivates PDK4 gene phan nuclear receptor ERRα: a expression via the or for tran scriptional control of muscle glucose metabolism 显示文摘 | WENDE A R HUSS J M SCHAEFFER P J | 2005 | Mol Cell Biol2005,25,10: | 1 |
| 12 | Fuel specification, energyconsumption and CO2 emission in oil refineries显示文摘 | SZKLO A SCHAEFFER R | 2007 | En-ergy2007,32,7: | 1 |
| 13 | A class of nonharmonic fourier series显示文摘 | Duffin R J Schaeffer A G | 1952 | Trans Am Math Soc1952,72,: | 1 |
| 14 | A Class of Nonharmonic Fourier Series显示文摘 | Duffin R Schaeffer A | 1952 | Transactions of the American Mathematical Society1952,72,2: | 1 |
| 15 | Energy and carbon embodied in the international trade of Brazil:an input-output approach显示文摘 | Machado G Schaeffer R Worrell E | | 0,,3: | 1 |
| 16 | A class of nonharmonic fourier series显示文摘 | DUFFIN R SCHAEFFER | 1952 | Trans Amer Math Soc1952,72,: | 1 |
| 17 | Energy and carbon embodied in the international trade of Brazil: an input-output approach显示文摘 | Machado G Schaeffer R Worrell E | 2001 | Ecological Economics2001,39,3: | 1 |
| 18 | Greenhouse gas emissions from hydroelectric reserw~irs 显示文摘 | ROSA L P SCHAEFFER R | 1994 | Ambio1994,23,: | 1 |
| 19 | Energy and Carbon Embodied in the International Trade of Brazil: An Input-output Approach 显示文摘 | Machado G Schaeffer R Worrell E | 2001 | Ecological Economics2001,39,3: | 1 |
| 20 | The Embodiment of Carbon Associated with Brazilian Imports and Exports 显示文摘 | Schaeffer R Leal A | 1996 | Energy Conversion and Management1996,37,68: | 1 |