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| 1 | Liver surgery in cirrhosis and portal hypertension显示文摘The prevalence of hepatic cirrhosis in Europe and the United States, currently 250 patients per 100000 inhabitants, is steadily increasing. Thus, we observe a significant increase in patients with cirrhosis and portal hypertension needing liver resections for primary ormetastatic lesions. However, extended liver resections in patients with underlying hepatic cirrhosis and portal hypertension still represent a medical challenge in regard to perioperative morbidity, surgical management and postoperative outcome. The Barcelona Clinic Liver Cancer classification recommends to restrict curative liver resections for hepatocellular carcinoma in cirrhotic patients to early tumor stages in patients with Child A cirrhosis not showing portal hypertension. However, during the last two decades, relevant improvements in preoperative diagnostic, perioperative hepatologic and intensive care management as well as in surgical techniques during hepatic resections have rendered even extended liver resections in higher-degree cirrhotic patients with portal hypertension possible. However, there are few standard indications for hepatic resections in cirrhotic patients and risk stratifications have to be performed in an interdisciplinary setting for each individual patient. We here review the indications, the preoperative risk-stratifications, the morbidity and the mortality of extended resections for primary and metastatic lesions in cirrhotic livers. Furthermore, we provide a review of literature on perioperative management in cirrhotic patients needing extrahepatic abdominal surgery and an overview of surgical options in the treatment of hepatic cirrhosis. | Christina Hackl Hans J Schlitt Philipp Renner Sven A Lang | 2016 | World Journal of Gastroenterology2016，22，9： | 21 |
| 2 | Survival benefit in patients after palliative resection vs non-resection colon cancer surgery显示文摘AIM: To evaluate survival in patients undergoing pallia- tive resection versus non-resection surgery for primary colorectal cancer in a retrospective analysis. METHODS: Demographics, TNM status, operating de- tails and survival were reviewed for 67 patients under- going surgery for incurable colorectal cancer. Palliative resection of the primary tumor was performed in 46 cases in contrast to 21 patients with non-resection of the primary tumor and bypass surgery. Risk factors for post- operative mortality and poor survival were analyzed with univariate and multivariate analyses.RESULTS: The two groups were comparable in terms of age, gender, preoperative presence of ileus and tumor stage. Multivariate analysis showed that median survival was significantly higher in patients with palliative resec- tion surgery (544 vs 233 d). Differentiation of the tumor and tumor size were additional independent factors that were associated with a significantly poorer survival rate. CONCLUSION: Palliative resection surgery for primary colorectal cancer is associated with a higher median survival rate. Also, the presence of liver metastasis and tumor size are associated with poor survival. Therefore, resection of the primary tumor should be considered in patients with non-curable colon cancer. | A Beham M Rentsch K Püllmann L Mantouvalou H Spatz HJ Schlitt A Obed | 2006 | World Journal of Gastroenterology2006，12，41： | 5 |
| 3 | Anti-inflammatory effects of phospholipid transfer protein (PLTP) deficiency in mice显示文摘 | SCHLITT A LIU J YAN D | 2005 | Biochim Biophys Acta2005，1733，23： | 1 |
| 4 | High plasma phospholipid transfer protein levels as a risk factor for coronary artery disease 显示文摘 | Schlitt A Biekel C Thumma P | 2003 | Artcrioscler Thromb Vase Biol2003，23，10： | 1 |
| 5 | Further evaluation of plasma sphingomyelin levels as a risk factor for coronary artery disease显示文摘 | Schlitt A Blankenberg S Yan D | 2006 | Nutr Metab (Lond)2006，3，： | 1 |
| 6 | Recurrence patterns ofhepatocellular and fibrolamellar carcinoma after liver transplantation显示文摘 | Schlitt HJ Neipp M Weimann A | 1999 | J Clin Oncol1999，17，1： | 1 |
| 7 | CD14^+ CD16^+ monocytes in coronary artery disease and their relationship to serum TNF-alpha levels 显示文摘 | Schlitt A Heine GH Blankenberg S | 2004 | Thromb Haemost2004，92，2： | 1 |
| 8 | Building and analyzing genomewide gene disruption networks 显示文摘 | Rung J Schlitt T Brazama A | 2002 | Bioinformatics2002，2，： | 1 |
| 9 | Recurrence patterns of hepatocellular and fibrolamellar carcinoma after liver transplantation显示文摘 | Schlitt HJ Neipp M Weimann A | 1999 | J Clin Oncol1999，17，1： | 1 |
| 10 | Recurrence of secondary hy- perparathyroidism in patients after total parathyroidectomy with autotransplantation: technical and therapeutic aspects显示文摘 | Agha A Loss M Schlitt HJ | 2012 | Eur Arch Otorhinolaryngol2012，269，5： | 1 |
| 11 | Anti-inflammatory effects of phospholipid transfer protein (PLTP) deficiency in mice 显示文摘 | Schlitt A Liu J Yan D | 2005 | Bioehim Biophys Aeta2005，1733，2： | 1 |
| 12 | High Plasma phospholipid transfer protein levels as a risk factor for coronary artery disease显示文摘 | Schlitt A Bickel C Thumma P | 2003 | Arterioscler Thromb Vasc Biol2003，23，10： | 1 |
| 13 | Prognostic value of lipoproteins and their relation to inflammatory markers among patients with coronary artery disease显示文摘 | Schlitt A Blankenberg S Bickel C | 2005 | Int J Cardiol2005，102，3： | 1 |
| 14 | High Plasma phospholipid transfer protein levels as a risk factor for coronary artery disease显示文摘 | Schlitt A Bickel C Thumma P | 2003 | Arterioscler:Thromb Vasc Biol2003，23，10： | 1 |
| 15 | Further evaluation of plasma sphingomyelin levels as a risk factor for coronary artery disease 显示文摘 | Schlitt A Blankenberg S Yah D | 2006 | Nutr Metab(Lond)2006，5，： | 1 |
| 16 | CD14^+ CD16^+monocytes in coronary artery disease and their rela- tionship to serum TNF-alpha levels 显示文摘 | Schlitt A Heine GH Blankenberg S | 2004 | Thromb Haemost2004，92，2： | 1 |
| 17 | Apoptosis contributes to septic cardiomyopathy and is improved by simvastatin ther- apy显示文摘 | Buerke U Carter JM Schlitt A | 2007 | Shock2007，29，4： | 1 |
| 18 | Evaluation of boundary element methods for the EEG forward problem:effect of linear interpolation显示文摘 | SCHLITT H A HELLER L AARON R | 1995 | IEEE Trans Biomed Eng1995，42，： | 1 |
| 19 | High plasma phospholipid transfer protein levels as a risk factor for coronary artery disease显示文摘 | SCHLITT A BICKEL C THUMMA P | 2003 | Arterioseler Thromb Vase Bioh2003，3，18： | 1 |
| 20 | CD14^+CD16^+ monocytes in coronary artery disease and their relationship to serum TNF-a levels显示文摘 | Schlitt A Heine GH Blankenberg S | 2004 | Thromb Haemost2004，92，2： | 1 |
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