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| 1 | The determinants of national innovative capacity显示文摘 | Jeffrey L Furman Michael E Porter Scott Stern | 2002 | Research Policy2002,,6: | 12 |
| 2 | Efficacy of peroral endoscopic myotomy vs other achalasia treatments in improving esophageal function显示文摘AIM: To assess and compare the esophageal function after peroral endoscopic myotomy(POEM) vs other conventional treatments in achalasia.METHODS: Chart review of all achalasia patients who underwent POEM, laparoscopic Heller myotomy(LHM) or pneumatic dilation(PD) at our institution between January 2012 and March 2015 was performed. Patient demographics, type of achalasia, prior treatments, pre- and post-treatment timed barium swallow(TBE) and high-resolution esophageal manometry(HREM) findings were compared between the three treatment groups. Patients who had both pre- and 2 mo posttreatment TBE or HREM were included in the final analysis. TBE parameters compared were barium column height, width and volume of barium remaining at 1 and 5 min. HREM parameters compared were basal lower esophageal sphincter(LES) pressures and LES-integrated relaxation pressures(IRP). Data are presented as mean ± SD, median [25th, 75 th percentiles] or frequency(percent). Analysis of variance, KruskalWallis test, Pearsons χ~2 test and Fishers Exact tests were used for analysis.RESULTS: A total of 200 achalasia patients were included of which 36 underwent POEM, 22 underwent PD and 142 underwent LHM. POEM patients were older(55.4 ± 16.8 years vs 46.5 ± 15.7 years, P = 0.013) and had higher BMI than LHM(29.1 ± 5.9 kg/m^2 vs 26 ± 5.1 kg/m^2, P = 0.012). More number of patients in POEM and PD groups had undergone prior treatments compared to LHM group(72.2% vs 68.2% vs 44.3% respectively, P = 0.003). At 2 mo post-treatment, all TBE parameters including barium column height, width and volume remaining at 1 and 5 min improved significantly in all three treatment groups(P = 0.01 to P < 0.001) except the column height at 1 min in PD group(P = 0.11). At 2 mo post-treatment, there was significant improvement in basal LES pressure and LES-IRP in both LHM(40.5 mm Hg vs 14.5 mm Hg and 24 mm Hg vs 7.1 mm Hg respectively, P < 0.001) and POEM groups(38.7 mm Hg vs 11.4 mm Hg and 23.6 mm Hg vs 6.6 mm Hg respectively, P < 0.001). However, when the efficacy of three treatments were compared to each other in terms of improvement in TBE or HREM parameters at 2 mo, there was no significant difference(P > 0.05).CONCLUSION: POEM, PD and LHM were all effective in improving esophageal function in achalasia at shortterm. There was no difference in efficacy between the three treatments. | Madhusudhan R Sanaka Umar Hayat Prashanthi N Thota Ramprasad Jegadeesan Monica Ray Scott L Gabbard Neha Wadhwa Rocio Lopez Mark E Baker Sudish Murthy Siva Raja | 2016 | World Journal of Gastroenterology2016,22,20: | 7 |
| 3 | Inflammation and Alzheimer’s disease显示文摘 | Haruhiko Akiyama Steven Barger Scott Barnum Bonnie Bradt Joachim Bauer Greg M Cole Neil R Cooper Piet Eikelenboom Mark Emmerling Berndt L Fiebich Caleb E Finch Sally Frautschy W.S.T Griffin Harald Hampel Michael Hull Gary Landreth Lih–Fen Lue Robert Mrak | 2000 | Neurobiology of Aging2000,,3: | 2 |
| 4 | Cardiovascular physiology in the older adults显示文摘 | Xuming Dai Scott L Hummel Jorge B Salazar George E Taffet Susan Zieman Janice B Schwartz | 2015 | Journal of Geriatric Cardiology2015,12,3: | 2 |
| 5 | Calcium anidotrihydroborate:a hydrogen storage material显示文摘 | Diyabalanage H V K Shrestha R P Semelsberger TA Scott B L Bowden M E Davis B L Burrell A K | | 0,,47: | 1 |
| 6 | The determinants of national innovative capacity显示文摘 | Jeffrey L Furman Michael E Porter Scott Stern | 2002 | Research Policy2002,,6: | 1 |
| 7 | Isolation and immunization studies of a canine paro-like virus from dogs with haemorrhagic enteritis显示文摘 | APPEL M J SCOTT F W CARMICHAEL L E | 1979 | Vet Rec1979,105,8: | 1 |
| 8 | LAMP proteins are required for fusion of lysosomes with phagosomes显示文摘 | Huynh K K Eskelinen E L Scott C C | 2007 | EMBO J2007,26,: | 1 |
| 9 | Encouraging 'frienAly'complaints behavior in industrial markets-reventing the loss of customers and reputation显示文摘 | Scott W Hansen John E Swan Thomas L Powers | 1996 | Industrial Marketing Management1996,,25: | 1 |
| 10 | Validation of the RTOG recursive partitioning analysis (RPA) classifica- tion for brain metastases显示文摘 | Gaspar L E Scott C Murray K | 2000 | Int J Radiat Oncol Biol Phys2000,47,4: | 1 |
| 11 | Parthenarpy in tomato 显示文摘 | George W L Scott J W Splittstoesser W E | 1984 | Horticultural Reviews1984,6,: | 1 |
| 12 | Treatment with interferon-a2b and ribavirin improves outcome in MERS-CoV-infected rhesus macaques 显示文摘 | Falzarano D de Wit E Rasmussen AL Feldmann F Oku- mura A Scott DP Brining D Bushmaker T Martellaro C Baseler L Benecke AG Katze MG Munster VJ Feldma- nn H | 2013 | Nat Med2013,19,10: | 1 |
| 13 | Single dose radiosurgical treatment of recurrent previously irradiated primary brain tumors and brain metastases:final report of RTOG protocol 90-05显示文摘 | Shaw E Scott C Souhami L | 2000 | Int J Radiat Oncol Biol Phys2000,47,2: | 1 |
| 14 | The Determinants of National Innovative Capacity显示文摘 | FURMAN JEFFERY L MICHAEL E P SCOTT STERN | 2002 | Research Policy2002,31,6: | 1 |
| 15 | Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders 显示文摘 | BAXTER E J SCOTT L M CAMPBELL P J | 2005 | Lancet2005,365,: | 1 |
| 16 | Standardly endmorphism algebras显示文摘 | Cline E Parshall B Scott L | 1996 | Mem Amer Math Soc1996,591,: | 1 |
| 17 | An instance of boron deficiency in the grape under field conditions显示文摘 | Scott L E | 1941 | Proc Amer Soc Hort Sci1941,38,: | 1 |
| 18 | Vitamins C and E improve regrowth and reduce lipid peroxidation of blackberry shoot tips following cryopreservation 显示文摘 | Esther E U Scott W L Maret G T | 2010 | Plant Cell Reports2010,29,1: | 1 |
| 19 | Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders显示文摘 | Baxter E J Scott L M Campbell P J | | 0,,: | 1 |
| 20 | The determinants of national innovative capacity显示文摘 | Jeffrey L Furman Michael E Porter Scott Stern | 2002 | Research Policy2002,,6: | 1 |