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124篇 您的检索式:作者名="SEARS K"
    题名 作者 年代 出处 被引量
1Oral eplerenone for the management of chronic central serous chorioretinopathy显示文摘AIM: To examine eplerenone(Inspra, Pfizer), a mineralocorticoid receptor antagonist, as a treatment option for chronic central serous chorioretinopathy(CSCR).METHODS: A retrospective consecutive case series was conducted for patients receiving oral eplerenone for chronic CSCR. At baseline and each follow-up visit,spectral domain optical coherence tomography(SD-OCT)imaging was performed, including manual measurements of the height and diameter size of subretinal fluid. The primary outcome measure was the reduction in subretinal fluid following initiation of therapy.RESULTS: A total of 17 eyes of 13 patients treated with25 and 50 mg of oral eplerenone per day were identified.Subretinal fluid(SRF) decreased over time following eplerenone therapy(P = 0.007 and P =0.002, diameter and height respectively). Maximum SRF height decreased from a mean of 131.5 μm at baseline to 15.3 μm at day181+. SRF diameter decreased from an average of 2174.4μm at baseline to 46.9 μm at day 181 +. Log MAR visual acuity improved from 0.42(Snellen equivalent: 20/53) at baseline to 0.29(Snellen equivalent: 20/39) at day 181 +(P = 0.024). Central subfield thickness(CST) decreased from 339.5 μm at baseline to 270.3 μm at day 181+(P = 0.029).CONCLUSION: Eplerenone therapy resulted in significant anatomic and visual improvements in eyes with chronic CSCR.Rishi P Singh Jonathan E Sears Rumneek Bedi Andrew P Schachat Justis P Ehlers Peter K Kaiser 2015International Journal of Ophthalmology(English edition)2015,8,2:6
2Pricing the SPIN 显示文摘Chen K Sears S 1990Financial Management1990,,:1
3Monarch larvae sensitivity to Bacillus thuringiensis purified proteins and pollen 显示文摘Hellmich R L Siegfried B D Sears M K 2001ProcNatlAcadSci USA2001,98,1:1
4Density and activity characterization of activated sludge floes显示文摘SEARS K ALLEMAN J E BARNARD J L 2006Environ Eng2006,132,:1
5AE37 : a novel T- cell-eliciting vaccine for breast cancer 显示文摘Sears A K Perez S A Clifton G T 2011Expert Opin Biol Ther2011,11,11:1
6A patient's guide to living confidently with chronic heart failure 显示文摘Sears SF Woodrow L Cutitta K 2013Circulation2013,127,13:1
7Acute endophthalmitis following intravitreal triamcinolone acetonide injection显示文摘Darius M Moshfeghi Peter K Kaiser Ingrid U Scott Jonathan E Sears Matthew Benz Juan P Sinesterra Richard S Kaiser Sophie J Bakri Raj K Maturi Jonathan Belmont Paul M Beer Timothy G Murray Hugo Quiroz-Mercado William F Mieler 2003American Journal of Ophthalmology2003,,5:1
8The relation- ship between immunologic response and recurrence in a phase II trial evaluating the HER-2/neu peptide vaccines AE37 and GP2 in breast cancer patients in the adjuvant setting 显示文摘Sears A K Clifton G T Benavides L C 2011J Am Coll Surg2011,213,3:1
9A weak calcium binding site in subtilisin BPN has a dramatic effect on protein stability 显示文摘R D Kidd H P Yennawar P Sears CH Wong G K Farber 1996Am Chem Soc1996,118,:1
10A transmission electron microscopy study of defects formed through the capping layer of self-assembled InAs/GaAs quantum dot samples显示文摘Sears K Wong-Leung J Tan H H 0,,11:1
11Gasification of brown coal and char with carbon dioxide in the presence of finely dispersed iron catalysts显示文摘Asami K Sears P Furimsky E 1996Fuel Processing Technology1996,47,2:1
12Induced sputum cell count:their usefulness in clinic peactice显示文摘Jayaram L Parameswaran K Sears MR 2000Eur Respir J2000,16,1:1
13Experimented methods in cancer therapeutics 显示文摘Widder K J Sennei A E Sears B 1982J Pharm Sc/1982,71,:1
14Volatility, price resolution, and the effectiveness of price limits 显示文摘Ma C K Rao R P Sears R S 1989Journal of Financial Services Research1989,,3:1
15A weak calcium binding site in subtilisin BPN-has a dramatic effect on protein stability显示文摘R D Kidd H P Yennawar P Sears C H Wong G K Farber 1996Am Chem Soc1996,118,:1
16A tumor suppressor role for PP2A-B56alpha through negative regulation of c-Myc and other key oncoproteins显示文摘ARNOLD H K SEARS R C 2008Cancer Metastasis Rev2008,27,2:1
17Gasification of brown coal and char with carbon dioxide in the presence of finely dispersed iron catalysts 显示文摘ASAMI K SEARS P FURIMSKY E 1996Fuel Processing Technology1996,47,:1
18The effects of whole-body compression garments on prolonged high-intensity intermittent exercise 显示文摘SEAR J A HOARE T K SCANLAN A T 2010J Strength Cond Res2010,24,7:1
19leaf tip cultures of the evening primrose allow stable, aseptic culture of mycoplasma-like organism 显示文摘Sears B B Klomparens K L 1989Canada Journal of Plant Pathology1989,11,:1
20Prediction of human rotavirus serotype by nucleotide sequence analysis of the VP7 protein gene显示文摘Green K Y Sears J F Taniguchi K 1988J Virol1988,62,:1
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