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| 1 | Comprehensive and innovative techniques for livertransplantation in rats: A surgical guide显示文摘AIM: To investigate our learning curves of orthotopic liver transplantation (OLT) in rats and the most important factor for successful surgery. METHODS: We describe the surgical procedures for our rat OLT model, and determined the operator learning curves. The various factors that contributed to successful surgery were determined. The most important surgical factors were evaluated between successful and unsuccessful surgeries.RESULTS: Learning curve data indicated that 50 cases were required for operator training to start a study. Operative time, blood loss, warm ischemic time, anhepatic phase, unstable systemic hemodynamic state, and body temperature after surgery significantly affected surgery success by univariate analysis, while the anhepatic phase was the most critical factor for success by multivariate analysis. CONCLUSION: OLT in rats is the only liver transplantation model that provides clinically relevant and reliable results. Shortened anhepatic phase is key to success in this model. | Tomohide Hori Justin H Nguyen Yasuhiro Ogura Toshiyuki Hata Shintaro Yagi Ann-Marie T Baine Norifumi Ohashi Christopher B Eckman Aimee R Herdt Hiroto Egawa Yasutsugu Takada Fumitaka Oike Seisuke Saka-moto Mureo Kasahara Kohei Ogawa Koichiro Hata Taku Iida Yukihide Yonekawa Lena Sibulesky Kagemasa Kuribayashi Takuma Kato Kanako Saito Mie Torii Naruhiko Sahara Naoko Kamo Tomoko Sahara Motohiko Yasutomi Shinji Uemoto | 2010 | World Journal of Gastroenterology2010，16，25： | 14 |
| 2 | Sensitive and convenient yeast reporter assay for high - throughput analysis by using a secretory luciferase from Cypridina noctiluca 显示文摘 | Tochigi Y Sato N Sahara T | 2010 | Anal Chem2010，82，13： | 1 |
| 3 | A novel immunosuppressive agent, SQDG, derived from sea urchin 显示文摘 | Matsumoto Y Sahara H Fujita T | 2000 | Transplant Proc2000，32，7： | 1 |
| 4 | A Novel Immunosupressive Agent, SQDG, Derived Sea Urchin显示文摘 | Sahara H Fujita T | 2000 | Transplatation Proceedings2000，32，： | 1 |
| 5 | Improved generation of HLA class I peptide tetramers显示文摘 | Sato Y Sahara H Tsukahara T | 2002 | J Immunol Methods2002，271，3： | 1 |
| 6 | Nifekalant hydrochloride, a novel class III antiarrhythmie agent, suppressed postoperative recurrent ventricular tachycardia in a patient undergoing coronary artery bypass grafting and the Dor approach显示文摘 | Sahara M Sagara K Yamashita T | 2003 | Circ J2003，67，8： | 1 |
| 7 | Impact of fracture networks on borehole breakout heterogeneities in crystalline rock显示文摘 | Sahara D P Schoenball M Kohl T | 2014 | International Journal of Rock Mechanics and Mining Sciences2014，71，10： | 1 |
| 8 | Deletion of angiotensin-converting enzyme 2 promotes the development of atherosclerosis and arterial neointima formation 显示文摘 | Sahara M Ikutomi M Motita T | 2014 | Cardiovasc Res2014，101，2： | 1 |
| 9 | Synthetic sulfonolipids deduced from sulfonoquinovosyl diacylglycerols of sea urchin reduces hepatic ischemia-reperfusinn injury in rats 显示文摘 | Tsuruma T Sahara H Takenouchi M | 2004 | Transplant Proc2004，36，7： | 1 |
| 10 | Photolysis of fluchloralin in aqueous methanol显示文摘 | SAHARA T BHATTACHARYYA A | 2001 | Pest Management Science2001，58，2： | 1 |
| 11 | Bitter gourd seed fatty acid rich in 9c, 11t, 13t - conjugated linolenic acid induces apoptosis and up -regulates the GADD45, p53 and PPARgamma in human colon cancer Caco- 2 cells 显示文摘 | YASUI Y HOSOKAWA M SAHARA T | 2005 | Prostaglandins Leukot Essent Fatty Acids2005，73，2： | 1 |
| 12 | Cloning, Sequencing, and Expression of a Gene Encoding the Monomeric Isocitrate Dehydrogenase of the Nitrogen-fixing Bacterium, Azotobacter vinelandii显示文摘 | SAHARA T TAKADA Y TAKEUCHI Y | 2002 | Biosci Biotechnol Biochem2002，66，3： | 1 |
| 13 | Multiple myeloma expressing CD19(+)CD56(-)phenotype显示文摘 | Ihara M Ono T | 2000 | Am J Hematol2000，64，4： | 1 |
| 14 | Twice-daily dosing of esomeprazole effectively inhibits acid secretion in CYP2C19 rapid metabolisers compared with twice-daily omeprazole, rabeprazole or lansoprazole显示文摘 | Sahara S Sugimoto M Uotani T | 2013 | Aliment Pharmacol Ther2013，38，9： | 1 |
| 15 | Effects of a new inmmnosuppres- sive agent, beta-SQAG9, in swine kidney transplantation 显示文摘 | Tanaka T Kitamura H Sahara H | 2007 | Transpl Immunol2007，18，1： | 1 |
| 16 | Reproduction of Japanese encephalitis virus in human glioma cells, 118MGC :inhibitory effect of host factor (s) 显示文摘 | Sahara M Takegami T | 1989 | Uirusu1989，39，2： | 1 |
| 17 | Synthetic sulfonol- ipids deduced from sulfonoquinovosyl diacylglycerors of sea urchin reduces hepatic ischemia reperfusion injury in rats显示文摘 | Tsumma T Sahara H Takeenouchi M | 2004 | Transplant Proc2004，36，7： | 1 |
| 18 | Bitter gourd seed fatty acid rich in9c, 11t, 13t- conjugated linolenic acid induces apoptosis and up-regulates the GADD45, p53 and PPARgamma in human colon cancer Caco- 2 cells 显示文摘 | Yasui Y Hosokawa M Sahara T | 2005 | Prostaglandins Leukot Essent Fatty Acids2005，73，： | 1 |
| 19 | The relationship be- tween venous hypertension and expression of vascular end- othelial growth factor: hemodynamic and immunohistoche- mical examinations in a rat venous hypertension model 显示文摘 | Kojima T Miyachi S Sahara Y | 2007 | Surg Neurol2007，68，： | 1 |
| 20 | Molecular differentiation of sexchromosomes probed by comparative genomichybridization显示文摘 | TRAUT W SAHARA K OTTO T D | 1999 | Chromo-soma1999，108，： | 1 |
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