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1篇 您的检索式：作者名="Samar Nassiri"

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		题名	作者	年代	出处	被引量
	1	Effect of periocular injection of celecoxib and propranolol on ocular level of vascular endothelial growth factor in a diabetic mouse model显示文摘AIM: To investigate the effects of periocular injection of propranolol and celecoxib on ocular levels of vascular endothelial growth factor(VEGF) in a diabetic mouse model.METHODS: Forty 4-6wk BALB-C male mice weighing20-25 g were used. The study groups included: non-diabetic control(group 1), diabetic control(group 2),diabetic propranolol(group 3), and diabetic celecoxib(group 4). After induction of type 1 diabetes by streptozotocin, propranolol(10 μg) and celecoxib(200 μg dissolved in carboxymethylcellulose 0.5%) were injected periocularly. The ocular level of VEGF was measured in all the study groups using enzyme-linked immuno sorbent assay(ELISA) method. RESULTS: Ocular VEGF level was significantly increased(1.25 fold) in the diabetic control group when compared to the non-diabetic group one week after induction with streptozotocin(P =0.002). Both periocular propranolol and celecoxib significantly reduced ocular VEGF levels(P =0.047 and P <0.001, respectively). The effect was more pronounced with celecoxib. CONCLUSION: The periocular administration of propranolol and celecoxib can significantly reduce ocular VEGF levels in a diabetic mouse model.	Samar Nassiri Gholamreza Houshmand Mostafa Feghhi Alireza Kheirollah Mohammad Bahadoram Nariman Nassiri	2016	International Journal of Ophthalmology(English edition)2016，9，6：	3

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