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1篇 您的检索式：作者名="Sarah Voon"

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		题名	作者	年代	出处	被引量
	1	Perfusability and immunogenicity of implantable pre-vascularized tissues recapitulating features of native capillary network显示文摘Vascularization is a key pre-requisite to engineered anatomical scale three dimensional(3-D)constructs to ensure their nutrient and oxygen supply upon implantation.Presently,engineered pre-vascularized 3-D tissues are limited to only micro-scale hydrogels,which meet neither the anatomical scale needs nor the complexity of natural extracellular matrix(ECM)environments.Anatomical scale perfusable constructs are critically needed for translational applications.To overcome this challenge,we previously developed pre-vascularized ECM sheets with long and oriented dense microvascular networks.The present study further evaluated the patency,perfusability and innate immune response toward these pre-vascularized constructs.Macrophage-co-cultured prevascularized constructs were evaluated in vitro to confirm micro-vessel patency and perturbations in macrophage metabolism.Subcutaneously implanted pre-vascularized constructs remained viable and formed a functional anastomosis with host vasculature within 3 days of implantation.This completely biological pre-vascularized construct holds great potential as a building block to engineer perfusable anatomical scale tissues.	Dhavan Sharma Archita Sharma Linghao Hu Te-An Chen Sarah Voon Kayla J.Bayless Jeremy Goldman Alex J.Walsh Feng Zhao	2023	Bioactive Materials2023，，12：	0

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