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| 1 | High-flow nasal oxygen availability for sedation decreases the use of general anesthesia during endoscopic retrograde cholangiopancreatography and endoscopic ultrasound显示文摘AIM To examine whether high-flow nasal oxygen(HFNO) availability influences the use of general anesthesia(GA) in patients undergoing endoscopic retrograde cholangiopancreatography(ERCP) and endoscopic ultrasound(EUS) and associated outcomes.METHODS In this retrospective study, patients were stratified into 3 eras between October 1, 2013 and June 30, 2014 based on HFNO availability for deep sedation at the time of their endoscopy. During the first and last 3-mo eras(era 1 and 3), no HFNO was available, whereas it was an option during the second 3-mo era(era 2). The primary outcome was the percent utilization of GA vs deep sedation in each period. Secondary outcomes included oxygen saturation nadir during sedation between periods, as well as procedure duration, and anesthesia-only time between periods and for GA vs sedation cases respectively.RESULTS During the study period 238 ERCP or EUS cases were identified for analysis. Statistical testing was employed and a P < 0.050 was significant unless the Bonferroni correction for multiple comparisons was used. General anesthesia use was significantly lower in era 2 compared to era 1 with the same trend between era 2 and 3(P = 0.012 and 0.045 respectively). The oxygen saturation nadir during sedation was significantly higher in era 2 compared to era 3(P < 0.001) but not between eras 1 and 2(P = 0.028) or 1 and 3(P = 0.069). The procedure time within each era was significantly longer under GA compared to deep sedation(P ≤ 0.007) as was the anesthesia-only time(P ≤ 0.001).CONCLUSION High-flow nasal oxygen availability was associated with decreased GA utilization and improved oxygenation for ERCP and EUS during sedation. | Roman Schumann Nikola S Natov Klifford A Rocuts-Martinez Matthew D Finkelman Tom V Phan Sanjay R Hegde Robert M Knapp | 2016 | World Journal of Gastroenterology2016，22，47： | 9 |
| 2 | 术后高血糖:胰岛素治疗的临床益处显示文摘手术损伤破坏了正常的调节机理,并引起术后恢复期多种代谢和内分泌改变。创伤、麻醉、出血、疼痛,甚至在沉思遭受刺激时的情景都可引起神经内分泌反应,使术后恢复期葡萄糖利用发生改变。临床上人们已认识到,非糖尿病和糖尿病患者都可发生术后高血糖。非糖尿病患者术后葡萄糖升高是暂时的,用于诊断糖尿病的标准不适宜在术后即刻采用。 | Schumann D 那瑾华 王安朝 | 1990 | 国外医学(内分泌学分册)1990，10，4： | 5 |
| 3 | Segmentingthe Non-adopter Category in the Diffusion of InternetBanking显示文摘 | LEE E J KWON K N SCHUMANN D W | 2005 | International Journal of Bank Market-ing2005，23，5： | 1 |
| 4 | Preparation of 26A1, SgNi, 44Ti, 3Mn and 6Fe from a proton ir- radiated copper beam dump显示文摘 | AYRANOV M SCHUMANN D | 2010 | Journal of Radio- analytical and Nuclear Chemistry2010，286，3： | 1 |
| 5 | Nanocelluloses as innovative polymers in research and application显示文摘 | Klemm D Schumann D Kramer F He(B)ler N Hornung M Schmauder H P Marsch S | | 0，，09： | 1 |
| 6 | Central and peripheral routes to advertising effectiveness:The moderating role of involvement显示文摘 | Petty tk E Cacioppo J T Schumann D | 1983 | Joumal of consumer research1983，10，2： | 1 |
| 7 | Nanocelluloses as innovative polymers in research and application显示文摘 | Klemm D Schumann D Kramer F | 2006 | Advances in Polymer Science2006，205，： | 1 |
| 8 | Bacterial synthesized cellulose-artificial blood vessels for microsurgery 显示文摘 | Klemm D Schumann D | 2001 | Prog Polym Sci2001，26，： | 1 |
| 9 | Postoperative hyperglycemia:Clinical bebefits of insulin therapy显示文摘 | SCHUMANN D R N F AAN | 1990 | Heart Lung1990，19，： | 1 |
| 10 | Establishment of a sim- ph and rapid method to screen for strong promoters in Bacillus subtilis显示文摘 | Phuong-Phan T T Nguyen H D Schumann W | 2010 | Pro Exp Purification2010，71，： | 1 |
| 11 | Establishment of an exper imental system allowing immobilization of proteins on the surface of Bacillus subtilis ceils显示文摘 | Nguyen H D Schumann W | 2006 | Journal of bio- technology2006，122，4： | 1 |
| 12 | Bacterial synthesizeo cellulose -artificial blood vessels for microsurgery 显示文摘 | KLEMM D SCHUMANN D UDHARDT U | 2001 | Progress in Polyme Science2001，26，： | 1 |
| 13 | Central and Peripheral Routes to Advertising Effectiveness: The Moderating Role of Involvement显示文摘 | PETTY R E CACIOPPO J T SCHUMANN D | 1983 | Journal of Consumer Research1983，10，2： | 1 |
| 14 | Early rectal stenosis following stapled rectal mucosectomy for hemorrhoids显示文摘 | Petersen S Hellmich G Schumann D | 2004 | BMC Surg2004，4，1： | 1 |
| 15 | Influence of Heat Input and Travel Speed on Mierostructure and Mechanical Properties of Double Tandem Submerged Arc High Strength Low Alloy Steel Weldments 显示文摘 | Viano D M Ahmed N U Schumann G O | 2000 | Science and Technology of Welding and Joining2000，5，1： | 1 |
| 16 | On-Line Separation of Short-Lived Tungsten Isotopes From Tantalum, Hafnium and Lutetium by Adsorption on Ion Exchangers From Aqueous Ammonia Solution显示文摘 | Schumann D Dressler R Taut S | 1996 | J Radioanal Nucl Chem Lett1996，214，1： | 1 |
| 17 | CEACAM1, a cell-cell adhesion molecule, directly associates with annexin lI in a three dimensional model of mammary morphogenesis 显示文摘 | Kirshner J Schumann D Shively J E | 2003 | The Journal of Biological Chemistry2003，278，50： | 1 |
| 18 | Potential role of tissue transglutaminase in glaucoma filtering surgery 显示文摘 | Priglinger SG Alge CS Kook D Thiel M Schumann R Eibl K | 2005 | Invest Ophthalmol Vis Sci2005，47，9： | 1 |
| 19 | Association of the toll-like receptor 2 A-16934T promoter polymorphism with severe atopie dermatitis 显示文摘 | Oh D Y Schumann R R Hamann L | 2009 | Allergy2009，64，11： | 1 |
| 20 | Cyclic, mechanical compression enhances chondrogenesis of mesenchymal progenitor cells in tissue engineering scaffolds显示文摘 | Angele P Schumann D Angele M | 2004 | Biorheology2004，41，3： | 1 |
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