|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Intrahepatic biliary cystic neoplasms:Surgical results of 9 patients and literature review显示文摘AIM: To investigate the eligible management of the cystic neplasms of the liver. METHODS: The charts of 9 patients who underwent surgery for intrahepatic biliary cystic liver neoplasms between 2003 and 2008 were reviewed retrospectively. Informed consent was obtained from the patients and approval was obtained from the designated review board of the institution. RESULTS: All patients were female with a median (range) age of 49 (27-60 years). The most frequent symptom was abdominal pain in 6 of the patients. Four patients had undergone previous laparotomy (with other diagnoses) which resulted in incomplete surgery or recurrences. Liver resection (n = 6) or enucleation (n = 3) was performed. The final diagnosis was intrahepaticbiliary cystadenoma in 8 patients and cystadenocarcinoma in 1 patient. All symptoms resolved after surgery. There has been no recurrence during a median (range) 31 (7-72) mo of follow up. CONCLUSION: In spite of the improvement in imaging modalities and increasing recognition of biliary cystadenoma and cystadenocarcinoma, accurate preoperative diagnosis may be difficult. Complete surgical removal (liver resection or enucleation) of these lesions yields satisfying long-term results. | Ali Emre Kür■at Rahmi Serin Ilgin zden Yaman Tekant Orhan Bilge Ayd■n Alper Mine Güllüoglu Koray Güven | 2011 | World Journal of Gastroenterology2011，17，3： | 15 |
| 2 | Serum positive cagA in patients with non-ulcer dyspepsia and peptic ulcer disease from two centers in different regions of Turkey显示文摘AIM: To investigate and compare frequencies of serum positive cagA in patients from two separate regions of Turkey who were grouped according to the presence of peptic ulcer disease or non-ulcer dyspepsia.METHODS: One hundred and eighty Helicobacter pyloripositive patients with peptic ulcer disease or non-ulcer dyspepsia were included in the study. One hundred and fourteen patients had non-ulcer dyspepsia and 66 had peptic ulcer disease (32 with gastric ulcers and/or erosions and 34with duodenal ulcers). Each patient was tested for serum antibody to H. pylori cagA protein by enzyme immunoassay.RESULTS: The total frequency of serum positive cagA in the study group was 97.2 %. The rates in the patients with peptic ulcers and in those with non-ulcer dyspepsia were 100% and 95.6%, respectively. These results were similar to those reported in Asian studies, but higher than those that have been noted in other studies from Turkey and Western countries.CONCLUSION: The high rates of serum positive cagA in these patients with peptic ulcer disease and non-ulcer dyspepsia were similar to results reported in Asia. The fact that there was high seroum prevalence regardless of ulcer status suggests that factors other than cagA might be responsible for ulceration or other types of severe pathology in H. pylori-positive individuals. | Ender Serin Uur Yilmaz Ganiye Künefeci Birol zer Yüksel Gümürdülü Mustafa Gülü Fazilet Kayaseluk Sedat Boyaciolu | 2003 | World Journal of Gastroenterology2003，9，4： | 10 |
| 3 | Effect of honey on bacterial translocation and intestinal morphology in obstructive jaundice显示文摘AIM:To evaluate the effects of honey on bacterial translocation and intestinal villus histopathology in experimental obstructive jaundice.METHODS:Thirty Wistar-Albino rats were randomly divided into three groups each including 10 animals:group Ⅰ,sham-operated;group Ⅱ,ligation and section of the common bile duct(BDL);group Ⅲ,bile duct ligation followed by oral supplementation of honey(BDL+honey) 10 g/kg per day.Liver,blood,spleen,mesenteric lymph nodes,and ileal samples were taken for microbiological,light and transmission electrone microscopic examination.RESULTS:Although the number of villi per centimeter and the height of the mucosa were higher in sham group,there was no statistically significant difference between sham and BDL + honey groups(P>0.05).On the other hand,there was a statistically significant difference between BDL group and other groups(P<0.05).The electron microscopic changes werealso different between these groups.Sham and honey groups had similar incidence of bacterial translocation(P>0.05).BDL group had significantly higher rates of bacterial translocation as compared with sham and honey groups.Bacterial translocation was predominantly detected in mesenteric lymph nodes.CONCLUSION:Supplementation of honey in presence of obstructive jaundice ameliorates bacterial translocation and improves ileal morphology. | Cem Gencay Kemal Kismet Bulent Kilicoglu Serap Erel Mehmet Ali Akkus Sibel Serin Kilicoglu Sabahattin Muratoglu Asli Elif Sunay Esra Erdemli | 2008 | World Journal of Gastroenterology2008，14，21： | 8 |
| 4 | Predictability of outcome of caustic ingestion by esophagogastroduodenoscopy in children显示文摘AIM: To assess the necessity of esophagogastroduodenoscopy (EGD) to predict the outcome of caustic ingestion in children. METHODS: The study included 206 children who underwent EGD because of ingestion of caustic substances between January 2005 and August 2010. Retrospective analysis of data of the patients was performed. RESULTS: The male/female ratio was 1.6 and mean age was 38.1 ± 28.8 mo. The caustic substances were acidic in 72 (34.9%) cases, alkaline in 56 (27.2%), liquid household bleach in 62 (30.1%), and unknown in 16 (7.8%). Fifty-seven (27.7%) patients were symptom-free. Significant clinical findings were observed in 149 (72.3%) patients. Upper gastrointestinal endoscopy findings of esophageal injury were grade 0 in 86 (41.7%) patients, grade 1 in 49 (23.8%), grade 2a in 42 (20.4%), grade 2b in 28 (13.6%), and grade 3a in 1 (0.5%) patient. 35 patients with grade 2a, 2b, and 3a injuries underwent esophageal dilation at second week of ingestion. Esophageal stricture, which necessitated a regular dilation program developed in 13 of the aforementioned 35 patients. There is no statistically significant difference in the rate of development of esophageal stricture between the patients who ingested acidic (15.3%) and alkaline (8.9%) substances (P = 0.32). Severe gastric injury was detected in 38 (18.5%) patients. The rate of development of gastric injury was significantly higher in the acidic group (14%) than in the alkaline group (2.9%) (P = 0.001). Out of 149 patients with clinical findings, 49 (32.9%) patients had no esophageal injury and 117 (78.5%) patients had no gastric lesion. Esophageal and severe gastric injuries were detected in 20 (35.1%) and 8 (14%) of patients with no clinical findings respectively. Pyloric stenosis developed in 6 patients. Pyloric obstruction improved with balloon dilation in 2 patients. Mean hospitalization time were 1.2 ± 0.5 d for grade 0 and 2.3 ± 5 d for grade 1 and 6.3 ± 6.2 d for grade 2a and 15.8 ± 18.6 d for grade 2b. It was significantly longer for patients with grade 2a and 2b injuries (P = 0.000). CONCLUSION: Endoscopy is an effective technique for determining the presence of esophageal and gastric damage and to avoid unnecessary treatment in patients with no or mild injury. | Abdulkerim Temiz Pelin Oguzkurt Semire Serin Ezer Emine Ince Akgun Hicsonmez | 2012 | World Journal of Gastroenterology2012，18，10： | 8 |
| 5 | Low eradication rate of Helicobacterpyloriwith triple 7-14 days and quadriple therapy in Turkey显示文摘AIM:The eradication rate of Helicobacter pylori (H pylon) shows variation among countries and regimens of treatment.We aimed to study the eradication rates of different regimens in our region and some factors affecting the rate of eradication.METHODS:One hundred and sixty-four Hpylori positivepatients (68 males, 96 females; mean age:48±12 years)with duodenal or gastric ulcer without a smoking history were included in the study. The patients were divided into three groups according to the treatment regimens. Omeprazole 20mg, clarithromycin 500mg, amoxicillin 1g were given twice daily for 1 week (Group I) and 2 weeks (Group Ⅱ).Patients in Group Ⅲ received bismuth subsitrate 300mg,tetracyline 500 mg and metronidazole 500mg four times daily in addition to Omeprazole 20mg twice daily.Two biopsies each before and after treatment were obtained from antrum and corpus, and histopathologically evaluated.Eradication was assumed to be successful if no Hpylorus was detected from four biopsy specimens taken after treatment. The effects of factors like age, sex, Hpyloridensity on antrum and corpus before treatment, the total Hpylori density, and the inflammation scores on the rate of Hpylori eradication were evaluated.RESULTS:The overall eradication rate was 42%. The rates in groups Ⅱ and Ⅲ were statistically higher than that in group I (P<0.05). The rates of eradication were 24.5%,40.7% and 61.5% in groups Ⅰ, Ⅱ and Ⅲ, respectively. The eradication rate was negatively related to either corpus Hpylori density or total Hpyloridensity (P<0.05).The median age was older in the group in which the eradication failed in comparison to that with successful eradication (55yr vs 39yr, P<0.001). No correlation between sex and Hpylori eradication was found.CONCLUSION: Our rates of eradication were significantly lower when compared to those reported in literature.We believe that advanced age and high Hpyloridensity are negative predictive factors for the rate of Hpylorieradication. | Yuksel Gumurdulu Ender Serin Birol zer Fazilet Kayaselcuk Kursat Ozsahin Arif Mansur Cosar Murat Gursoy Gurden Gur Ugur Yilmaz Sedat Boyacioglu | 2004 | World Journal of Gastroenterology2004，10，5： | 4 |
| 6 | Remote Navigation of Turtle by Controlling Instinct Behavior via Human Brain-computer Interface显示文摘 | Cheol-Hu Kim Bongjae Choi Dae-Gun Kim Serin Lee Sungho Jo Phill-Seung Lee | 2016 | Journal of Bionic Engineering2016，13，3： | 4 |
| 7 | Helicobacter pylori eradication lowers serum homocysteine level in patients without gastric atrophy显示文摘AIM: To determine whether Helicobacter pylori ( H pylori)infection caused hyperhomocysteinemia by altering serum vitamin B12, serum folate and erythrocyte folate levels and whether eradication of this organism decreased serum homocysteine level.METHODS: The study involved 73 dyspeptic H pylori-positive patients, none of them had gastric mucosal atrophy based on rapid urease test and histology. Out of 73 patients, 41 (56.2%) showed a successful eradication of Hpylori4 wk after the end of treatment. In these 41 patients, fasting serum vitamin B12, folate and homocysteine levels, and erythrocyte folate levels before and 4 wk after Hpylorieradication therapy were compared.RESULTS: The group with a successful eradication of Hpylori had significantly higher serum vitamin B12 and erythrocyte folate levels in the post-treatment period compared to those in pre-treatment period (210±97 pg/mL vs237±94pg/mL, P<0.O01 and 442±212 ng/mL vs 539±304 ng/mL,P = 0.024, respectively), but showed no significant change in serum folate levels (5.6±2.6 ng/mL vs 6.0±2.4 ng/mL,P= 0.341). Also, the serum homocysteine levels in this group were significantly lower after therapy (13.1±5.2 μmol/L vs 11.9±6.2 μmol/L, P = 0.002). Regression analysis showed that serum homocysteine level was positively correlated with age (P = 0.01) and negatively with serum folate level before therapy (P = 0.003).CONCLUSION: Eradication of H pylori decreases serum homocysteine even in patients who do not exhibit gastric mucosal atrophy. It appears that the level of homocysteine in serum is related to a complex interaction among serum vitamin B12, serum folate and erythrocyte folate levels. | Birol Ozer Ender Serin Yuksel Gumurdulu Fazilet Kayaselcuk Ruksan Anarat Gurden Gur Kemal Kul Mustafa Guclu Sedat Boyacioglu | 2005 | World Journal of Gastroenterology2005，11，18： | 3 |
| 8 | Parasitic Robot System for Waypoint Navigation of Turtle显示文摘在关于小活动机器人和 biomimetic 机器人的研究,尽管有许多进展,运动能力在技术仍然是一个主要问题。然而,进化在那里导致了是能够优秀运动的许多真实动物。这篇论文论述一个动物的运动能力被用于一项机器人任务的一个寄生机器人系统。我们选择了一只鳖为我们的第一个主人动物并且设计了能执行发生作用之人或物调节的一个寄生机器人。寄生机器人,被纳入鳖,能向一根轻射出二极管导致鳖的追踪目标的行为(带) 并且断然通过重复刺激反应增强行为相互作用。在超过五个星期训练会话以后,机器人能成功地在 waypoint 航行任务控制训练的鳖的运动的方向。这个混合动物机器人相互作用系统能在各种各样的领域里提供一个其他的解决方案给一些常规活动机器人系统的限制,并且能也为行为的科学充当一个有用相互作用系统。 | Dae-Gun Kim Serin Lee Cheol-Hu Kim Sungho Jo Phill-Seung Lee | 2017 | Journal of Bionic Engineering2017，14，2： | 3 |
| 9 | Value of computed tomography and magnetic resonance imaging for assessing severity of liver cirrhosis secondary to viral hepatitis显示文摘 | O. Barutcu Saygili N.C. Tarhan T. Yildirim E. Serin B. Ozer A.M. Agildere | 2004 | European Journal of Radiology2004，，3： | 3 |
| 10 | Profiles of serum microRNAs; miR-125b-5p and miR223-3p serve as novel biomarkers for HBV-positive hepatocellular carcinoma显示文摘 | Burcu Gurer Giray Gurol Emekdas Seda Tezcan Mahmut Ulger Mehmet Sami Serin Orhan Sezgin Engin Altintas Eyup Naci Tiftik | 2014 | Molecular Biology Reports2014，，7： | 2 |
| 11 | Multicentre, phase II study evaluating capecitabine monotherapy in patients with anthracycline- and taxane-pretreated metastatic breast cancer显示文摘 | P. Fumoleau R. Largillier C. Clippe V. Dièras H. Orfeuvre T. Lesimple S. Culine B. Audhuy D. Serin H. Curé E. Vuillemin J.-F. Morère F. Montestruc Z. Mouri M. Namer | 2003 | European Journal of Cancer2003，，4： | 2 |
| 12 | Ultrastructural view of colon anastomosis under propolis effect by transmission electron microscopy显示文摘AIM: To evaluate the effect of propolis administration on the healing of colon anastomosis with light and transmission electron microscopes. METHODS: Forty-eight Wistar-Albino female rats were divided into two groups and had colon resection and anastomosis. In group Ⅰ, rats were fed with standard rat chow pre- and postoperatively. The rats in group Ⅱ were fed with standard rat chow and began receiving oral supplementation of propolis 100 mg/kg per day beginning 7 d before the operation and continued until they were sacrificed. Rats were sacrificed 1, 3, 7 and 14 d after operation, and anastomotic bursting pressures measured. After the resection of anastomotic segments, histopathological examination was performed with light and transmission electron microscopes by two blinded histologists and photographed. RESULTS: The colonic bursting pressures of the propolis group were statistically significantly better than the control group. Ultrastructural histopathological analysis of the colon anastomosis revealed that propolis accelerated the phases of the healing process and stimulated mature granulation tissue formation and collagen synthesis of fibroblasts. CONCLUSION: Bursting pressure measurements and ultra structural histopathological evaluation showedthat administration of propolis accelerated the healing of colon anastomosis following surgical excision. | Sibel Serin Kilicoglu Bulent Kilicoglu Esra Erdemli | 2008 | World Journal of Gastroenterology2008，14，30： | 2 |
| 13 | Effect of abdominal trauma on hemorrhagic shock-induced acute lung injury in rats显示文摘瞄准:在老鼠在出血性的导致吃惊的尖锐的肺损害上评估腹的损伤的效果。方法:五个组被分配(n = 8 ) 在学习。我作为控制组,被带的组作为出血性的吃惊组,组织 II 是的组 III 出血性的吃惊 + 剖腹术,是的组 IV 是的出血性的吃惊 + 脾切除术和组 V 脾切除术 + 网膜切除术 + 出血性的吃惊组。出血性的吃惊被拉血并且在 10 min 以内把吝啬的动脉压(地图) 归结为 40 毫米汞柱导致。在 1 h 的一个低血压患者时期以后,动物被复活。Bronchoalveolar 洗室年龄(BAL ) 被执行在复活 malondialdehyde (MDA ) 以后与 BAL 液体的 40 mL 从牙槽的空间恢复房间, L-gamma-glutamyl-L-cysteinyl-glycine (GSH ) 层次在浆液,红血球和肺织物被测量。结果:浆液,红血球,肺织物 MDA 和 GSH 层次显著地在出血性的吃惊组 II-V 被增加(P <
0.05 ) 。在 BAL 液体的淋巴细胞, neutrophil 和牙槽的巨噬细胞计数显示了在控制和吃惊组之间的有效差量(P <
0.05 ) 。结论:损伤的度增加出血性的导致吃惊的尖锐的肺损害。 | Bulent Kilicoglu Erol Eroglu Sibel Serin Kilicoglu Kemal Kismet Fusun Eroglu | 2006 | World Journal of Gastroenterology2006，12，22： | 2 |
| 14 | Effects of honey as a scolicidal agent on the hepatobiliary system显示文摘AIM: To examine the effects of 10% diluted honey, which has been shown to be scolicidal, on the liver and biliary system and determine whether it could be used as a scolicidal agent in the presence of biliary-cystic communication. METHODS: Thirty Wistar-Albino rats were divided into two groups. Honey with 10% dilution in the study group and 0.9% saline (NaCl) in the control group were injected into the common bile ducts of rats through a 3-mm duodenotomy. The animals were sacrificed 6 mo after the procedure. Histopathological, biochemical, and radiological examinations were performed for evaluation of side effects. RESULTS: At the end of the sixth month, liver function tests were found to be normal in both groups. The tissue samples of liver and ductus choledochus of the honey group showed no histomorphologic difference from the control group. No stricture on the biliary tree was detected on the retrograde cholangiograms. CONCLUSION: According to these results, we concluded that 10% diluted honey could be used as scolicidal agent safely in the presence of biliary-cystic communication. | Bulent Kilicoglu Kemal Kismet Sibel Serin Kilicoglu Serap Erel Omur Gencay Kadriye Sorkun Esra Erdemli Okan Akhan Mehmet Ali Akkus Iskender Sayek | 2008 | World Journal of Gastroenterology2008，14，13： | 2 |
| 15 | Determination of plasma microRNA for early detection of gastric cancer显示文摘 | Aysegul Gorur Senay Balci Fidanci Nil Dogruer Unal Lokman Ayaz Serin Akbayir Hatice Yildirim Yaroglu Musa Dirlik Mehmet Sami Serin Lulufer Tamer | 2013 | Molecular Biology Reports2013，，3： | 2 |
| 16 | A study on the carotid artery intima media thickness and its association with lipidperoxidation显示文摘 | Konukoglu D Serin O Demiriz KG | 1998 | Clin Chim Acta1998，277，： | 1 |
| 17 | Serum leptin level can be a negative marker of hepatocyte damage in nonalcoholic fatty liver显示文摘 | Serin E Ozer B Gumurdulu Y | 2003 | J Gastroenterol2003，38，： | 1 |
| 18 | Regres- sion rate behavior of hybrid rocket solid fuels 显示文摘 | Chiaverini M J Serin N Johnson D K | 2000 | Journal of Propulsion and Power2000，16，1： | 1 |
| 19 | 查看详情显示文摘 | Tuncel M Serin S | | 0，，： | 1 |
| 20 | Synthesis and characterization of a new vicdioxime derivative of chitosan and its transition metal complexes 显示文摘 | Demetgu C Serin S | 2008 | Carbohydrate Polymers2008，72，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员