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| 1 | Benefit of neoadjuvant concurrent chemoradiotherapy for locally advanced perihilar cholangiocarcinoma显示文摘AIM To clarify the role of neoadjuvant concurrent chemoradiotherapy(NACCRT) followed by surgical resection for localized or locally advanced perihilar cholangiocarcinoma(CCA).METHODS We retrospectively reviewed 57 patients who underwent surgical resection with or without NACCRT for perihilar CCA; 12 patients received NACCRT and 45 patients did not received NACCRT. Patients with locally advanced perihilar CCA requiring NACCRT were defined as follows:(1) a mass involving unilateral branches of the portal vein or hepatic artery with insufficient volume of the anticipated remnant lobe; or(2) an infiltrating mass in the main portal vein that was too long for reconstruction, identified at preoperative staging. RESULTS The median disease-free survival(DFS) durations of the neoadjuvant and non-neoadjuvant CCRT groups were26.0 and 15.1 mo, respectively(P = 0.91). The median overall survival(OS) durations of the neoadjuvant and non-neoadjuvant CCRT groups were 32.9 and 27.1 mo, respectively(P = 0.26). The NACCRT group showed a downstaging tendency compared to the non-NACCRT group as compared with the tumor stage confirmed by histological examination after surgery and the tumor stage confirmed by imaging test at the time of diagnosis(P = 0.01). CONCLUSION NACCRT does not prolong DFS and OS in localized or locally advanced perihilar CCA. However, NACCRT may allow tumor downstaging and improve tumor resectability. | Jang Han Jung Hyun Jik Lee Hee Seung Lee Jung Hyun Jo In Rae Cho Moon Jae Chung Jeong Youp Park Seung Woo Park Si Young Song Seungmin Bang | 2017 | World Journal of Gastroenterology2017，23，18： | 21 |
| 2 | Design of low noise airfoil with high aerodynamic performance for use on small wind turbines显示文摘Wind power is one of the most reliable renewable energy sources and internationally installed capacity is increasing radically every year.Although wind power has been favored by the public in general,the problem with the impact of wind turbine noise on people living in the vicinity of the turbines has been increased.Low noise wind turbine design is becoming more and more important as noise is spreading more adverse effect of wind turbine to public.This paper demonstrates the design of 10 kW class wind turbines,each of three blades,a rotor diameter 6.4 m,a rated rotating speed 200 r/min and a rated wind speed 10 m/s.The optimized airfoil is dedicated for the 75% spanwise position because the dominant source of a wind turbine blade is trailing edge noise from the outer 25% of the blade.Numerical computations are performed for incompressible flow and for Mach number at 0.145 and for Reynolds numbers at 1.02×106 with a lift performance,which is resistant to surface contamination and turbulence intensity.The objectives in the design process are to reduce noise emission,while sustaining high aerodynamic efficiency.Dominant broadband noise sources are predicted by semi-empirical formulas composed of the groundwork by Brooks et al.and Lowson associated with typical wind turbine operation conditions.During the airfoil redesign process,the aerodynamic performance is analyzed to reduce the wind turbine power loss.The results obtained from the design process show that the design method is capable of designing airfoils with reduced noise using a commercial 10 kW class wind turbine blade airfoil as a basis.Therefore,the new optimized airfoil showing 2.9 dB reductions of total sound pressure level(SPL) and higher aerodynamic performance are achieved. | Taehyung KIM Seungmin LEE Hogeon KIM Soogab LEE | 2010 | Science China(Technological Sciences)2010，53，1： | 7 |
| 3 | Comparison of efficacy and safety between standard-dose and modified-dose FOLFIRINOX as a first-line treatment of pancreatic cancer显示文摘AIM To directly compare the efficacy and toxicity of standarddose FOLFIRINOX(sFOLFIRINOX) and modified-dose FOLFIRINOX(mFOLFIRINOX, 75% of standard-dose) for pancreatic cancer.METHODS One hundred and thirty pancreatic cancer patients who received sFOLFIRINOX(n = 88) or mFOLFIRINOX(n = 42) as their first-line chemotherapy from January 2013 to July 2017 were retrospectively reviewed. For efficacy analysis, the objective response rate(ORR),disease control rate(DCR), progression-free survival(PFS), and overall survival(OS) were evaluated and compared using Pearson's chi-square test, Kaplan-Meier plot and log-rank test. The adverse events(AEs) were evaluated, and severe(≥ grade 3) AEs rates of the two groups were compared for toxicity analysis.RESULTS The mFOLFIRINOX group included more female patients(30.7% vs 57.1%; P = 0.004) and older patients [age(median), 57 vs 63.5; P = 0.018] than the sFOLFIRINOX group. In the efficacy analysis, the ORR and DCR were not significantly different between the two groups(ORR: 39.8% vs 35.7%; P = 0.656; DCR: 80.7% vs 83.3%; P = 0.716). The median PFS and OS were also not different between the groups(PFS: 8.7 mo vs 8.1 mo, P = 0.272; OS: 13.9 mo vs 13.7 mo, P = 0.476). In the safety analysis with severe AEs, the rates of neutropenia(83.0% vs 66.7%; P = 0.044), anorexia(48.9% vs 28.6%; P = 0.029) and diarrhea(13.6% vs 0.0%; P = 0.009) were markedly lower in the mFOLFIRINOX group.CONCLUSION m FOLFIRINOX showed comparable efficacy but better safety compared to sFOLFIRINOX. If clinically necessary, initiating FOLFIRINOX with 75% of the standard-dose can alleviate toxicity concerns without compromising efficacy. | Huapyong Kang Jung Hyun Jo Hee Seung Lee Moon Jae Chung Seungmin Bang Seung Woo Park Si Young Song Jeong Youp Park | 2018 | World Journal of Gastrointestinal Oncology2018，10，11： | 6 |
| 4 | Dynamic Inertia Response Support by Energy Storage System with Renewable Energy Integration Substation显示文摘In recent years,the expansion of renewable energy in electric power systems has been increasing at such a rapid pace that it has started affecting frequency stability.Renewable generators connected to the grid produce variable amounts of power,and in most cases have no inherent inertia response(IR)to the system frequency.Therefore,the high penetration of renewable generators in the system results in low inertia and frequency distortion.If renewable generators account for a high proportion of the supply in a power system,the use of energy storage systems(ESSs)with frequency-support algorithms(in the place of synchronous generators)can stabilize the network.The participation of ESSs in frequency support must be organized precisely,so that they are fully devoted to their own purpose.In this paper,the frequency-support parameters of ESSs are calculated for achieving stable frequency response from a network.An estimation and calibration process is conducted during the active power-order change of the ESSs in the substation,and is verified through electromagnetic-transients-including-DC(EMTDC)-based simulations. | Yeuntae Yoo Seungmin Jung Gilsoo Jang | 2020 | Journal of Modern Power Systems and Clean Energy2020，8，2： | 5 |
| 5 | Multicenter phase Ⅱ trial of modified FOLFIRINOX in gemcitabine-refractory pancreatic cancer显示文摘AIM To evaluate the efficacy and safety of modified FOLFIRINOX as a second-line treatment for gemcitabine(GEM)-refractory unresectable pancreatic cancer(PC).METHODS This study was a prospective, multicenter, one-arm, open-label, phase Ⅱ trial. Patients with unresectable PC, who showed disease progression during GEMbased chemotherapy were enrolled. All patients were administered FOLFIRINOX with reduced irinotecan and oxaliplatin(RIO; irinotecan 120 mg/m^2 and oxaliplatin 60 mg/m^2), which was set according to the phase Ⅰ study of FOLFIRINOX. The objective response rate(ORR), disease control rate(DCR), progressionfree survival(PFS), overall survival(OS), adverse events were evaluated. Additionally, changes in quality of life(QoL) were assessed using a questionnaire on QoL.RESULTS Between August 2015 and May 2016, a total of 48 patients were enrolled. The median follow-up time was 259 d with a median of 8.5 cycles. The ORR and DCR were 18.8% and 62.5%, respectively, including one patient who showed complete remission. The median PFS was 5.8 mo [95% confidence interval(CI): 3.7-7.9] and median OS was 9.0 mo(95%CI: 6.4-11.6). Neutropenia(64.6%) was the most common grade 3-4 adverse event, followed by febrile neutropenia(16.7%). Although 14.6% of patients experienced grade 3 fatigue, most non-hematologic AEs were under grade 2. In the QoL analysis, the global health status score before treatment was not different from the score at the last visit after treatment(45.43 ± 22.88 vs 48.66 ± 24.14, P = 0.548).CONCLUSION FOLFIRINOX with RIO showed acceptable toxicity and promising efficacy for GEM-refractory unresectable PC. However, this treatment requires careful observation of treatment-related hematologic toxicities. | Moon Jae Chung Huapyong Kang Ho Gak Kim Jong Jin Hyun Jun Kyu Lee Kwang Hyuck Lee Myung Hwan Noh Dae Hwan Kang Sang Hyub Lee Seungmin Bang 无 | 2018 | World Journal of Gastrointestinal Oncology2018，10，12： | 3 |
| 6 | Long Short Term Memory Networks Based Anomaly Detection for KPIs显示文摘In real-world many internet-based service companies need to closely monitor large amounts of data in order to ensure stable operation of their business.However,anomaly detection for these data with various patterns and data quality has been a great challenge,especially without labels.In this paper,we adopt an anomaly detection algorithm based on Long Short-Term Memory(LSTM)Network in terms of reconstructing KPIs and predicting KPIs.They use the reconstruction error and prediction error respectively as the criteria for judging anomalies,and we test our method with real data from a company in the insurance industry and achieved good performance. | Haiqi Zhu Fanzhi Meng Seungmin Rho Mohan Li Jianyu Wang Shaohui Liu Feng Jiang | 2019 | Computers, Materials & Continua2019，，8： | 2 |
| 7 | Oxyntic gland adenoma endoscopically mimicking a gastric neuroendocrine tumor: A case report显示文摘Gastric adenocarcinoma is one of the most common malignancies worldwide.Histochemical and immunohistologic analyses classify the phenotypes of gastric adenocarcinoma into several groups based on the variable clinical and pathologic features.A new and rare variant of gastric adenocarcinoma with chief cell differentiation(GA-CCD)has recently been recognized.Studies reporting the distinct clinicopathologic characteristics proposed the term oxyntic gland polyp/adenoma because of the benign nature of the GACCD.Typically,GA-CCD is a solitary mucosal lesion that develops either in the gastric cardia or fundus.Histologically,this lesion is characterized by tightly clustered glands and anastomosing cords of chief cells.Immunohistochemically,GA-CCD is diffusely positive for mucin(MUC)6 and negative for MUC2and MUC5AC.However,other gastric tumors such as a gastric neuroendocrine tumor or fundic gland polyp have been difficult to exclude.Because GA-CCD tends to be endoscopically misdiagnosed as a neuroendocrine tumor or fundic gland polyp,comprehensive assessment and observation by an endoscopist are strongly recommended.Herein,we report a rare case of oxyntic gland adenoma endoscopically mimicking a gastric neuroendocrine tumor that was successfully removed by endoscopic mucosal resection. | Tae-In Lee Jae-Young Jang Seungmin Kim Jung-Wook Kim Young-Woon Chang Youn-Wha Kim | 2015 | World Journal of Gastroenterology2015，21，16： | 2 |
| 8 | Differential diagnosis between gallbladder adenomas and cholesterol polyps on contrast-enhanced harmonic endoscopic ultrasonography显示文摘 | Chan Hyuk Park Moon Jae Chung Tak Geun Oh Jeong Youp Park Seungmin Bang Seung Woo Park Hyunki Kim Ho Kyoung Hwang Woo Jung Lee Si Young Song | 2013 | Surgical Endoscopy2013，，4： | 2 |
| 9 | Endoscopic Papillary Large Balloon Dilatation Alone Is Safe and Effective for the Treatment of Difficult Choledocholithiasis in Cases of Billroth II Gastrectomy: A Single Center Experience显示文摘 | Hui Won Jang Kyong Joo Lee Moon Jae Jung Joo Won Jung Jeong Youp Park Seung Woo Park Si Young Song Jae Bock Chung Seungmin Bang | 2013 | Digestive Diseases and Sciences2013，，6： | 2 |
| 10 | Experimental and Theoretical Investigation of Flim Condensation with Noncon- Densable Gas 显示文摘 | SEUNGMIN OH SHRIPAD T REVANKAR | 2006 | International Journal of Heat and Mass Transfer2006，，49： | 1 |
| 11 | Revision of bilateral self-expandable metallic stents placed using the stent-in-stent technique for malignant hilar biliary obstruction显示文摘Background: Endoscopic biliary decompression using bilateral self-expandable metallic stent(SEMS) placed using the stent-in-stent(SIS) technique is considered favorable for unresectable malignant hilar biliary obstruction(MHBO). However, occlusion of the bilateral SIS placement is frequent and revision can be challenging. This study was performed to investigate the efficacy, the long-term patency and the appropriate approach for revision of occluded bilateral SIS placement in unresectable MHBO. Methods: From January 2011 to July 2016, thirty-eight patients with unresectable MHBO underwent revision of occluded bilateral SIS placement. Clinical data including success rates and patency of revision, were retrospectively analyzed. Results: The technical success rate of revision was 76.3%. The clinical success rate of revision was 51.7% and mean patency of revision was 49.1 days. No significant predictive factor for clinical failure of revision was observed. The cell size of SEMS was not found to have significant effects on clinical success rates or revision patency. Conclusions: Revision of occluded bilateral SIS placement for MHBO showed fair patency and clinical success rate. Revision method and cell size of SEMS were not found to influence clinical outcomes. | Jun Hyuk Son Hee Seung Lee Sang Hyub Lee Seungmin Bang Jinwoo Kang Woo Hyun Paik Ji Kon Ryu Yong-Tae Kim | 2018 | Hepatobiliary & Pancreatic Diseases International2018，17，5： | 1 |
| 12 | Optimal design of the front linkage of a hydraulic excavator for multiobjective function显示文摘 | Kim Jong-won Jung Seungmin Kim Jinuk Kim Jongwon Seo Tae-won | 2014 | Journal of M echanical Science and Technology2014，28，8： | 1 |
| 13 | Structure identification and dissociation enthalpy measurements of the CO2+N2 hydrates for their application to CO2 capture and storage显示文摘 | Yohan L Seungmin L Jaehyoung L | 2014 | Chemical Engineering Journal2014，246，： | 1 |
| 14 | The Clinical Usefulness of 18-Fluorodeoxyglucose Positron Emission Tomography in the Differential Diagnosis, Staging, and Response Evaluation After Concurrent Chemoradiotherapy for Pancreatic Cancer显示文摘 | Seungmin Bang Hye Won Chung Seung Woo Park Jae Bock Chung Mijin Yun Jong Doo Lee Si Young Song | 2006 | Journal of Clinical Gastroenterology2006，，10： | 1 |
| 15 | Placement of a fully covered self-expandable metal stent in a young patient with chronic pancreatitis显示文摘Plastic stent insertion is a treatment option for pancreatic duct stricture with chronic pancreatitis.However, recurrent stricture is a limitation after removing the plastic stent.Self-expandable metal stents have long diameters and patency.A metal stent has become an established management option for pancreatic duct stricture caused by malignancy but its use in benign stricture is still controversial.We introduce a young patient who had chronic pancreatitis and underwent several plastic stent insertions due to recurrent pancreatic duct stricture.His symptoms improved after using a fully covered self-expandable metal covered stent and there was no recurrence found at follow-up at the outpatient department. | Kyong Joo Lee Kwang Joon Kim Dong Ho Shin Joo Won Chung Jeong Youp Park Seungmin Bang Seung Woo Park Si Young Song | 2010 | World Journal of Gastrointestinal Endoscopy2010，2，11： | 1 |
| 16 | CMV enteritis causing ileal perforation in underlying lupus enteritis显示文摘 | Seungmin Bang Yong-Beom Park Byung Seung Kang Min Chan Park Min Ho Hwang Ho Keun Kim Soo-Kon Lee | 2004 | Clinical Rheumatology2004，，1： | 1 |
| 17 | Experimental and Theoretical Investigation of Film Condensation with Non-Condensable Gas显示文摘 | Seungmin Oh Shripad T Revankar | 2006 | International Journal of Heat and Mass Transfer2006，49，： | 1 |
| 18 | Hospitalized heart failure: rates and long-term mortality显示文摘 | Eyal Shahar Seungmin Lee Joseph Kim Sue Duval Cheryl Barber Russell V. Luepker | 2004 | Journal of Cardiac Failure2004，，5： | 1 |
| 19 | Protective effects of ursodeoxycholic acid against 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced testicular damage in mice显示文摘 | YOUNGIl K JEDEUK Y SEUNGMIN O | 2004 | Toxicology and Applied Pharmacology2004，194，： | 1 |
| 20 | Controlling the synthesis of TaC nanopowders by injecting liquid precursor into RF induction plasma显示文摘 | Takamasa I seungmin O Li Jiguang | 2005 | Science and Technology of Advanced Materials2005，6，2： | 1 |
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