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| 1 | Formaldehyde induces toxic effects and regulates the expression of damage response genes in BM-MSCs显示文摘在这研究,我们在老鼠骨头髓上估计了甲醛(FA ) 的有毒的效果间充质的干细胞(BM-MSCs ) 。Cytotoxicity 被使用 MTT 试金测量。DNA 海滨破裂被与朊酶 K (PK ) 修改的标准碱的彗星试金和彗星试金检测。DNAprotein 交叉连接(DPC ) 被 KCl-SDS 降水试金检测。我们发现在从 75 ~ 200 M 的集中的 FA 禁止了房间幸存并且在 125 M 上导致了 DPC。修改 PK 的彗星试金证明那导致 FA 的 DNA 海滨破裂从 75 ~ 200 M 以一种剂量依赖者方式被增加。在另一方面,标准碱的彗星试金证明那 DNA 海滨破裂在 125 M 上与 FA 集中被减少。我们由使用在 DPC 和幸存率之间有否定线性关联的皮尔森关联证实了(r = 0.987, P < 0.01 ) 并且在 DPC 和(i) 姐妹染色单体交换之间的积极线性关系并且(ii ) micronucleus (r = 0.995, P < 0.01;r = 0.968, P < 0.01 ) 。DNA 损坏 RT2 剖析程序聚合酶链反应数组被用来在损坏反应基因的表达式调查变化。相应再结合小径的核苷酸切除修理小径和 Brca2, Rad51,和 Xrcc2 的 Xpa 和 Xpc 都在 75 和 125 M FA 是起来调整的。然而,一样的基因与 175 M FA 是下面调整的。Chek1 和 Hus1 的表情,涉及房间周期规定,与 75, 125,和 175 M FA 以一样的方式被改变。这些结果显示 Xpa, Xpc, Brca2, Rad51, Xrcc2, Chek1,和 Hus1 是必要的让 BM-MSCs 抵抗 FA 的效果。 | Yali She Yi Li Yongqi Liu Guli Asai Shaobo Sun Jianxin He Zheng Pan Yan Cui | 2013 | Acta Biochimica et Biophysica Sinica2013，45，12： | 8 |
| 2 | Whole-genome sequencing provides insights into the genetic diversity and domestication of bitter gourd(Momordica spp.)显示文摘Bitter gourd(Momordica charantia)is a popular cultivated vegetable in Asian and African countries.To reveal the characteristics of the genomic structure,evolutionary trajectory,and genetic basis underlying the domestication of bitter gourd,we performed whole-genome sequencing of the cultivar Dali-11 and the wild small-fruited line TR and resequencing of 187 bitter gourd germplasms from 16 countries.The major gene clusters(Bi clusters)for the biosynthesis of cucurbitane triterpenoids,which confer a bitter taste,are highly conserved in cucumber,melon,and watermelon.Comparative analysis among cucurbit genomes revealed that the Bi cluster involved in cucurbitane triterpenoid biosynthesis is absent in bitter gourd.Phylogenetic analysis revealed that the TR group,including 21 bitter gourd germplasms,may belong to a new species or subspecies independent from M.charantia.Furthermore,we found that the remaining 166 M.charantia germplasms are geographically differentiated,and we identified 710,412,and 290 candidate domestication genes in the South Asia,Southeast Asia,and China populations,respectively.This study provides new insights into bitter gourd genetic diversity and domestication and will facilitate the future genomics-enabled improvement of bitter gourd. | Junjie Cui Yan Yang Shaobo Luo Le Wang Rukui Huang Qingfang Wen Xiaoxia Han Nansheng Miao Jiaowen Cheng Ziji Liu Changyuan Zhang Chengcheng Feng Haisheng Zhu Jianwen Su Xinjian Wan Fang Hu Yu Niu Xiaoming Zheng Yulan Yang Dai Shan Zhensheng Dong Weiming He Narinder P.S.Dhillon Kailin Hu | 2020 | Horticulture Research2020，7，1： | 7 |
| 3 | Progress of Jinping Underground laboratory for Nuclear Astrophysics(JUNA)显示文摘Jinping Underground laboratory for Nuclear Astrophysics(JUNA) will take the advantage of the ultra-low background of CJPL lab and high current accelerator based on an ECR source and a highly sensitive detector to directly study for the first time a number of crucial reactions occurring at their relevant stellar energies during the evolution of hydrostatic stars. In its first phase, JUNA aims at the direct measurements of^(25)Mg(p,γ)^(26)Al,^(19)F(p,α)^(16)O,^(13)C(α,n)^(16)O and ^(12)C(α,γ)^(16)O reactions. The experimental setup,which includes an accelerator system with high stability and high intensity, a detector system, and a shielding material with low background, will be established during the above research. The current progress of JUNA will be given. | WeiPing Liu ZhiHong Li JiangJun He XiaoDong Tang Gang Lian Zhu An JianJun Chang Han Chen QingHao Chen XiongJun Chen ZhiJun Chen BaoQun Cui XianChao Du ChangBo Fu Lin Gan Bing Guo GuoZhu He Alexander Heger SuQing Hou HanXiong Huang Ning Huang BaoLu Jia LiYang Jiang Shigeru Kubono JianMin Li KuoAng Li Tao Li YunJu Li Maria Lugaro XiaoBing Luo HongYi Ma ShaoBo Ma DongMing Mei YongZhong Qian JiuChang Qin Jie Ren YangPing Shen Jun Su LiangTing Sun WanPeng Tan Isao Tanihata Shuo Wang Peng Wang YouBao Wang Qi Wu ShiWei Xu ShengQuan Yan LiTao Yang Yao Yang XiangQing Yu Qian Yue Sheng Zeng HuanYu Zhang Hui Zhang LiYong Zhang NingTao Zhang QiWei Zhang Tao Zhang XiaoPeng Zhang XueZhen Zhang ZiMing Zhang Wei Zhao Zuo Zhao Chao Zhou | 2016 | Science China(Physics,Mechanics & Astronomy)2016，59，4： | 3 |
| 4 | Polycrystalline diamond MESFETs by Au-mask technology for RF applications显示文摘Metal-semiconductor field effect transistors (MESFETs) were fabricated on H-terminated polycrystalline diamond.The DC characteristics of the p-channel MESFET showed a maximum drain current density of 204 mA/mm at a gate-source voltage of 6 V,and a maximum transconductance of 20 mS/mm at a gate-source voltage of 1.5 V.The small signal S-parameters of MESFET with 2 100 m gate width and 2 m gate length were measured.An extrinsic cut-off frequency (fT) of 1.7 GHz and the maximum oscillation frequency (fmax) of 2.5 GHz were obtained,which was the first report on diamond MESFETs with RF characteristics in China. | FENG ZhiHong WANG JingJing HE ZeZhao DUN ShaoBo YU Cui LIU JinLong ZHANG PingWei GUO Hui LI ChengMing CAI ShuJun | 2013 | Science China(Technological Sciences)2013，56，4： | 2 |
| 5 | Clinical efficacy of transjugular intrahepatic portosystemic shunt created through left or right branches of the portal vein:A meta-analysis显示文摘Background and aim:Transjugular intrahepatic portosystemic shunt(TIPS)is a technique successfully used to treat portal hypertension and its complications.However,the choice of the branch,left(L)or right(R),of the portal vein resulting in a better outcome is still under debate.Therefore,this meta-analysis aims to evaluate which branch has a better curative effect on patients treated with TIPS.Methods:PubMed,EMBASE,Web of science,Cochrane Library databases,Wanfang database and CBM were used for our search in October 2019 and updated in June 2021.The following parameters were used in evaluation:overall mortality,hepatic encephalopathy,shunt dysfunction,variceal rebleeding and rate of postoperative ascites.Results:There were seven studies included.The sample size was 1940.A lower risk of mortality was observed in TIPS-L-treated patients compared with TIPS-R-treated ones(OR=0.65,95%CI=0.50-0.85,p=0.002).A lower risk of shunt dysfunction was observed in TIPS-L-treated patients compared with TIPS-R-treated ones(OR=0.53,95%CI=0.33-0.87,p=0.01).And the TIPS-L group had a significantly higher hepatic encephalopathy-free rate than the TIPS-R group(OR=0.59,95%CI=0.44-0.78,p=0.0002).However,the rate of rebleeding(OR=0.75,95%CI=0.55-1.03,p=0.07)and incidence of postoperative ascites(OR=1.14,95%CI=0.86-1.51,p=0.38)was not statistically significant between the two groups.Conclusions:Based on the currently available evidence,the technique of TIPS through the left branch of the portal vein can significantly reduce the occurrence of overall postoperative mortality,hepatic encephalopathy and shunt dysfunction. | Shaobo Zhai Qi Cui Fang Dong Shiqi Wen Moubo Si Quan Chen | 2021 | Journal of Interventional Medicine2021，4，4： | 2 |
| 6 | 320-fold luminescence enhancement of [Ru(dpp)3]Cl2 dispersed on PMMA opal photonic crystals and highly improved oxygen sensing performance显示文摘Ru complexes([Ru(dpp)3]Cl2)were spin coated on poly(methyl methacrylate)(PMMA)opal photonic crystals(PhCs),and a,320-fold luminescence enhancement was observed compared to that on glass,which is the largest luminescence enhancement of dye molecules by the modulation of three-dimensional(3D)PhCs reported until now.The enhancement mechanism was carefully examined and it was shown that the luminescence of[Ru(dpp)3]Cl2 depended on the molecule concentration and temperature.It can be concluded that the suppressed non-radiative relaxation among the molecules and the field enhancement both contribute significantly to the luminescence enhancement.The PMMA PhC/Ru complex composites were then tested for their intracellular oxygen sensing and cell imaging properties;these composites effectively improved the limit of detection(LOD)and the brightness of the cell images. | Pingwei Zhou Donglei Zhou Li Tao Yongsheng Zhu Wen Xu Sai Xu Shaobo Cui Lin Xu Hongwei Song | 2014 | Light(Science & Applications)2014，3，1： | 1 |
| 7 | Machine-learning-empowered multispectral metafilm with reduced radar cross section,low infrared emissivity,and visible transparency显示文摘For camouflage applications,the performance requirements for metamaterials in different electromagnetic spectra are usually contradictory,which makes it difficult to develop satisfactory design schemes with multispectral compatibility.Fortunately,empowered by machine learning,metamaterial design is no longer limited to directly solving Maxwell’s equations.The design schemes and experiences of metamaterials can be analyzed,summarized,and learned by computers,which will significantly improve the design efficiency for the sake of practical engineer-ing applications.Here,we resort to the machine learning to solve the multispectral compatibility problem of metamaterials and demonstrate the design of a new metafilm with multiple mechanisms that can realize small microwave scattering,low infrared emissivity,and visible transparency simultaneously using a multilayer back-propagation neural network.The rapid evolution of structural design is realized by establishing a mapping between spectral curves and structural parameters.By training the network with different materials,the designed network is more adaptable.Through simulations and experimental verifications,the designed architecture has good accuracy and robustness.This paper provides a facile method for fast designs of multispectral metafilms that can find wide applications in satellite solar panels,aircraft windows,and others. | RUICHAO ZHU JIAFU WANG JINMING JIANG CUILIAN XU CHE LIU YUXIANG JIA SAI SUI ZHONGTAO ZHANG TONGHAO LIU ZUNTIAN CHU JUN WANG TIE JUN CUI SHAOBO QU | 2022 | Photonics Research2022，10，5： | 1 |
| 8 | von Willebrand factor as a novel noninvasive predictor of portal hypertension and esophageal varices in hepatitis B patients with cirrhosis显示文摘 | Hao Wu Shiping Yan Guangchuan Wang Shaobo Cui Chunqing Zhang Qiang Zhu | 2015 | Scandinavian Journal of Gastroenterology2015，，9： | 1 |
| 9 | Prognostic relevance of circulating endothelial progenitor cells for severe traumatic brain injury显示文摘 | Dasen Gong Mu Hao Li Liu Chunxiang Liu Jingfei Dong Zhuang Cui Lin Sun Shaobo Su Jianning Zhang | 2012 | Brain Injury2012，，3： | 1 |
| 10 | Effects of Amino Acid or Fulibao Nutritional Additives on Slaughter Performance and Pork Quality of Pigs显示文摘[Objective]The paper was to study the effects of amino acid or Fulibao nutritional additives on slaughter performance and pork quality of pigs,and to provide a theoretical basis for improving pork quality in pig breeding industry.[Method]Six Landrace×Yorkshire castrated male piglets were divided into three groups.The piglets in the first group were fed with conventional diet and used as the control.The piglets in the experimental group I were fed with the conventional diet supplementing 0.1%Fulibao,and those in the experimental group II were fed with the conventional diet supplementing 0.36%compound amino acid preparation.The piglets were reared for 2 months before being slaughtered.[Result]The average daily gains of piglets in the experimental groups I and II were 17.7%and 6.73%higher than that in the control group,but there was no difference in feed/gain ratio among the three groups.The dressing percentages of piglets in the experimental groups I and II were 2.7%and 1.72%higher than that in the control group,and the lean meat percentages were 3.5%and 7.97%higher than that in the control group,respectively.The meat fat ratios in the two experimental groups were significantly higher than that in the control group.The intermuscular fat in the experimental group II was significantly higher than that in the control group.However,the contents of intermuscular fat and inosinic acid in the experimental group II were significantly lower than those in the control group.[Conclusion]Both additives can improve the average daily gain and main slaughter performance of pigs,but can not improve the inosine acid content,and the compound amino acid preparation can not improve the intermuscular fat content. | Li Shaobo Zheng Boqiang Li Xiuliang Huang Jie Du Lijuan Sun Qinju Yang Cui Yang Jiahuang | 2022 | Animal Husbandry and Feed Science2022，14，4： | 0 |
| 11 | Determination of Double Beta Decay Half-Life of 136Xe with the PandaX-4T Natural Xenon Detector显示文摘Precise measurement of two-neutrino double beta decay(DBD)half-life is an important step for the searches of Majorana neutrinos with neutrinoless double beta decay.We report the measurement of DBD half-life of 136xe using the Pandax-4T dual-phase Time Projection Chamber(TPC)with 3.7-tonne natural xenon and the first 94.9-day physics data release. | Lin Si Zhaokan Cheng Abdusalam Abdukerim Zihao Bo Wei Chen Xun Chen Yunhua Chen Chen Cheng Yunshan Cheng Xiangyi Cui Yingjie Fan Deqing Fang Changbo Fu Mengting Fu Lisheng Geng Karl Giboni Linhui Gu Xuyuan Guo Ke Han Changda He Jinrong He Di Huang Yanlin Huang Zhou Huang Ruquan Hou Xiangdong Ji Yonglin Ju Chenxiang Li Jiafu Li Mingchuan Li Shu Li Shuaijie Li Qing Lin Jianglai Liu Xiaoying Lu Lingyin Luo Yunyang Luo Wenbo Ma Yugang Ma Yujun Mao Yue Meng Nasir Shaheed Xiaofeng Shang Xuyang Ning Ningchun Qi Zhicheng Qian Xiangxiang Ren Changsong Shang Guofang Shen Wenliang Sun Andi Tan Yi Tao Anqing Wang Meng Wang Qiuhong Wang Shaobo Wang Siguang Wang Wei Wang Xiuli Wang Zhou Wang Yuehuan Wei Mengmeng Wu Weihao Wu Jingkai Xia Mengjiao Xiao Xiang Xiao Pengwei Xie Binbin Yan Xiyu Yan Yong Yang Chunxu Yu Jumin Yuan Ying Yuan Zhe Yuan Dan Zhang Minzhen Zhang Peng Zhang Shibo Zhang Shu Zhang Tao Zhang Li Zhao Qibin Zheng Jifang Zhou Ning Zhou Xiaopeng Zhou Yong Zhou | 2023 | Research2023，，2： | 0 |
| 12 | Effects of gate dielectric thickness and semiconductor thickness on device performance of organic field-effect transistors based on pentacene显示文摘In this paper,the pentacene-based organic field-effect transistors(OFETs)with poly(methyl methacrylate)(PMMA)as gate dielectrics were fabricated,and the effects of gate dielectric thickness and semiconductor thickness on the device performance were investigated.The optimal PMMA thickness is in the range of 350–400 nm to sustain a considerable current density and stable performance.The device performance depends on the thicknesses of the active layer non-monotonically,which can be explained by the morphology of the pentacene film and the position of the conducting channel in the active layer.The device with a pentacene thickness of 50 nm shows the best performance,which has a maximum hole mobility of 1.12 cm2/V·s.In addition,the introduction of a thin layer of tris-(8-hydroxyquinolinato)aluminum(Alq3)to the OFETs as a light-emitting material greatly decreases the device performance. | YI Ran LOU ZhiDong HU YuFeng CUI ShaoBo TENG Feng | 2014 | Science China(Technological Sciences)2014，57，6： | 0 |
| 13 | Effects of Addition of Amino Acids or Soybean Phospholipid in Diet on Slaughter Performance and Meat Quality of Pigs显示文摘[Objectives]The study aims to discuss the effects of addition of arginine and glutamic acid or soybean phospholipid,vitamin E and yeast selenium in diet on the slaughter performance and meat quality of long(white)×large(York)binary hybrid pigs.[Methods]27 long×large castrated hybrid boars with the body weight of(54.4±0.15)kg were randomly divided into 3 groups,with 3 replicates per group and 3 pigs per replicate.Group A was the control group,in which the pigs were fed basal diet;in group B,0.8%arginine and 0.60%glutamate were added to the basal diet;in group C,75 g of soybean phospholipid,20 g of vitamin E and 8 g of yeast selenium were added to every 100 kg of the basal diet.The trial period was 60 d.After the experiment was ended,one test pig with similar body weight was selected from each replicate for slaughter and meat determination.[Results]The average weight gain and eye muscle area of the pigs in group B were significantly higher than those in group C(P<0.05),and also showed an increasing trend compared with group A,but there was no statistically significant difference(P>0.05);there was no significant difference between group B or C and group A in the average weight gain and eye muscle area(P>0.05).There was no significant difference in other slaughter performance between the three groups(P>0.05).Besides,there was also no significant difference in the content of various amino acids,total amino acids and total umami amino acids between the three groups(P>0.05).The inosine content in the longissimus dorsi muscle and muscle cooking loss of binary hybrid pigs in group C were significantly better than those in group B(P<0.05),and also had a tendency to be better than those in group A,but there was no significant difference(P>0.05);there was no significant difference between group B or C and group A in the inosine content and muscle cooking loss of the pigs(P>0.05).In addition,there was no significant difference in other meat traits and chemical composition of the longissimus dorsi muscle between group B or C and group A(P>0.05).[Conclusions]The addition of arginine and glutamic acid or soybean phospholipid,vitamin E and yeast selenium in diet had no significant effect on the growth rate,slaughter performance and meat traits of long×large binary hybrid pigs. | Sicong LUO Shaobo LI Xiangyun HU Min CHEN Lingxiu GAN Tingju HUANG Wenjie LU Junxiang HUANG Haimei DENG Jiahuang YANG Cui YANG Xiuliang LI | 2023 | Asian Agricultural Research2023，15，4： | 0 |
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