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| 1 | A complete sequence and comparative analysis of a SARS-associated virus(Isolate BJ01)显示文摘The genome sequence of the Severe Acute Respiratory Syndrome (SARS)-associated virus provides essential information for the identification of pathogen(s), exploration of etiology and evolution, interpretation of transmission and pathogenesis, development of diagnostics, prevention by future vaccination, and treatment by developing new drugs. We report the complete genome sequence and comparative analysis of an isolate (BJ01) of the coronavirus that has been recognized as a pathogen for SARS. The genome is 29725 nt in size and has 11 ORFs (Open Reading Frames). It is composed of a stable region encoding an RNA-dependent RNA polymerase (composed of 2 ORFs) and a variable region representing 4 CDSs (coding sequences) for viral structural genes (the S, E, M, N proteins) and 5 PUPs (putative uncharacterized proteins). Its gene order is identical to that of other known coronaviruses. The sequence alignment with all known RNA viruses places this virus as a member in the family of Coronaviridae. Thirty putative substitutions have been identified by comparative analysis of the 5 SARS- associated virus genome sequences in GenBank. Fifteen of them lead to possible amino acid changes (non-synonymous mutations) in the proteins. Three amino acid changes, with predicted alteration of physical and chemical features, have been detected in the S protein that is postulated to beinvolved in the immunoreactions between the virus and its host. Two amino acid changes have been detected in the Mprotein, which could be related to viral envelope formation. Phylogenetic analysis suggests the possibility of non-human origin of the SARS-associated viruses but provides noevidence that they are man-made. Further efforts should focus on identifying the etiology of the SARS-associated virus and ruling out conclusively the existence of otherpossible SARS-related pathogen(s). | QIN E'de ZHU Qingyu YU Man FAN Baochang CHANG Guohui SI Bingyin YANG Bao PENG Wenming JIANG Tao LIU Bohua DENG Yongqiang LIU Hong ZHANG Yu WANG Cui LI Yuquan GAN Yonghua LI Xiaoyu L Fushuang TAN Gang CAO Wuchun, YANG Ruifu Institute of Microbiology and Epidemiology, Chinese Academy of Military Medical Sciences, Beijing 100071, China WANG Jian, LI Wei, XU Zuyuan, LI Yan, WU Qingfa, LIN Wei, CHEN Weijun, TANG Lin, DENG Yajun, HAN Yujun, LI Changfeng, LEI Meng, LI Guoqing, LI Wenjie, L Hong, SHI Jianping, TONG Zongzhong, ZHANG Feng, LI Songgang, LIU Bin, LIU Siqi, DONG Wei, WANG Jun, Gane K-S Wong, YU Jun & YANG Huanming* Beijing Genomics Institute, Chinese Academy of Sciences, Beijing 101300 National Center for Genome Information, Beijing 101300, China | 2003 | Chinese Science Bulletin2003，48，10： | 121 |
| 2 | Expression of calreticulin is associated with infiltration of T-cells in stage ⅢB colon cancer显示文摘AIM: To investigate the correlation between expression of calreticulin and infiltration of lymphocytes in stage ⅢB colon cancer. METHODS: Sixty-eight pathologically-confirmed speci-mens were obtained from stage ⅢB (T3N1M0) colon cancer patients who underwent radical resection between January 1999 and May 2002 at the Cancer Center of Sun Yat-Sen University, Guangzhou, China. Immuno-histochemical analysis was performed to show infiltration of lymphocytes and expression of calreticulin in colon cancer. Association between calreticulin expression, infiltration of lymphocytes, and 5-year survival rate of patients was assessed. RESULTS: The expression level of calreticulin was lower in cancer nest than in its adjacent normal epithelium since 61.8% (42/68) of the samples were stained with calreticulin in colon cancer. The expression of calreticulin in colon cancer was associated with the infi ltration of CD45RO+ cells rather than with that of CD3+ cells. In addition, the stronger expression of calreticulin and the higher infiltration of CD3+ and CD45RO+ cells in colon cancer were associated with the higher 5-year survival rate of patients. CONCLUSION: Expression of calreticulin is associated with infiltration of T-cells, which implies that a low expression level of molecular marker may represent a new mechanism underlying immune escape in colon cancer. | Rui-Qing Peng, Ya Ding, Xing Zhang, Yi-Xin Zeng, Xiao- Shi Zhang, State Key Laboratory of Oncology in South China, Biotherapy Center, Cancer Center, Sun Yat-Sen University, 651 Dongfeng R E, Guangzhou 510060, Guangdong Province, China Ying-Bo Chen, Zhi-Wei Zhou, State Key Laboratory of Oncology in South China, Department of Gastric and Pancreatic Oncology, Cancer Center, Sun Yat-Sen University, 651 Dongfeng R E, Guangzhou 510060, Guangdong Province, China Rong Zhang, State Key Laboratory of Oncology in South China, Department of Endoscopy, Cancer Center, Sun Yat-Sen University, 651 Dongfeng R E, Guangzhou 510060, Guangdong Province, China Xing-Juan Yu, Yi-Xin Zeng, State Key Laboratory of Oncology in South China, Department of Experimental Research, Cancer Center, Sun Yat-Sen University, 651 Dongfeng R E, Guangzhou 510060, Guangdong Province, China | 2010 | World Journal of Gastroenterology2010，16，19： | 16 |
| 3 | The impact of cleft lip and palate repair on maxillofacial growth显示文摘Surgical correction is central to current team-approached cleft treatment. Cleft surgeons are always concerned about the impact of their surgical maneuver on the growth of the maxilla. Hypoplastic maxilla, concaved mid-face and deformed dental arch have constantly been reported after cleft treatments. It is very hard to completely circumvent these postoperative complications by current surgical protocols. In this paper, we discussed the factors that inhibit the maxillofacial growth on cleft patients. These factors included pre-surgical intervention, the timing of cleft palate and alveolae repair, surgical design and treatment protocol.Also, we made a review about the influence on the maxillary growth in un-operated cleft patients. On the basis of previous researches, we can conclude that most of scholars express identity of views in these aspects: early palatoplasty lead to maxilla growth inhibition in all dimensions; secondary alveolar bone graft had no influence on maxilla sagittal growth; cleft lip repair inhibited maxilla sagittal length in patients with cleft lip and palate; Veau's pushback palatoplasty and Langenbeck's palatoplasty with relaxing incisions were most detrimental to growth; Furlow palatoplasty showed little detrimental effect on maxilla growth;timing of hard palate closure, instead of the sequence of hard or soft palate repair, determined the postoperative growth. Still,scholars hold controversial viewpoints in some issues, for example, un-operated clefts have normal growth potential or not,pre-surgical intervention and pharyngoplasty inhibited maxillofacial growth or not. | Bing Shi Joseph E Losee | 2015 | International Journal of Oral Science2015，7，1： | 16 |
| 4 | Environment as the Stage for Economic Actors显示文摘The relative importance of economics and environment in debate may soon be reversed due to the influence of three fac- tors. Firstly, in the global economy it is hard to hide the unwanted products of economic processes. Secondly, huge advances in sci- ence will reduce the imperfect knowledge of markets, making some monitoring and analyzing tools show the design of sensible and equitable livelihood in communities, which is more important than the motivation of maximising profits for some individuals or firms. Thirdly, China, as the last major player on the planet to take on economic growth, comes from traditions fundamentally differ- ent from those economies that have experienced the Industrial Revolution previously. Its challenges with sustainability and en- vironmental conservation predate Western economics by millennia, and it is implementing policies domestically and starting to work on the world stage that acknowledges that the surroundings are the host for any economic and socio-political system. | John E Coulter Shi Lei Samantha Jenkins | 2007 | Chinese Journal of Population,Resources and Environment2007，5，1： | 10 |
| 5 | Detecting prostate cancer and prostatic calcifications using advanced magnetic resonance imaging显示文摘前列腺癌症和 prostatic 石灰化在老人有高发生。我们试图在检测前列腺癌症和 prostatic 石灰化调查危险性加权的成像的诊断能力。156 个人的一个全部的数字,与前列腺癌症包括 34 并且 122 在这研究与良性的前列腺被注册。计算断层摄影术,常规磁性的回声成像,散开加权的成像,和危险性加权的成像在所有病人上被执行。112 prostatic 石灰化在 87 个病人被检测。常规磁性的回声成像,明显的散开系数,和在检测前列腺癌症和 prostatic 石灰化的过滤危险性的阶段图象的敏感和特性是计算的。McNemars Chi 平方测试被用来在在这些技术之间的敏感和特性比较差别。结果证明在检测 prostatic 癌症的过滤危险性的阶段图象的敏感和特性比常规磁性的回声成像和明显的散开系数的大(P < 0.05 ) 。另外,在检测 prostatic 石灰化的过滤危险性的阶段图象的敏感和特性比得上计算断层摄影术的并且比常规磁性的回声成像和明显的散开系数的大(P < 0.05 ) 。在前列腺癌症给危险性加权的成像(SWI ) 的高发生反常,我们断定危险性加权的成像在检测前列腺癌症比常规磁性的回声成像,散开加权的成像,和计算断层摄影术更敏感、特定。而且,危险性加权的成像能识别类似于计算断层摄影术的 prostatic 石灰化,并且它比常规磁性的回声成像和散开加权的成像好一些。 | Shewei Dou Yan Bai Ankit Shandil Degang Ding Dapeng Shi E Mark Haacke Meiyun Wang | 2017 | Asian Journal of Andrology2017，19，4： | 7 |
| 6 | Comparison of non-schistosomal rectosigmoid cancer and schistosomal rectosigmoid cancer显示文摘AIM: To compare the clinicopathological features of patients with non-schistosomal rectosigmoid cancer and schistosomal rectosigmoid cancer.METHODS: All the patients with rectosigmoid carcinoma who underwent laparoscopic radical surgical resection in the Shanghai Minimally Invasive Surgical Center at Ruijin Hospital affiliated to Shanghai JiaoTong University between October 2009 and October2013 were included in this study. Twenty-six cases of colonic schistosomiasis diagnosed through colonoscopy and pathological examinations were collected. Symptoms,endoscopic findings and clinicopathological characteristics were evaluated retrospectively.RESULTS: There were no significant differences between patients with and without schistosomiasis in gender, age, CEA, CA19-9, preoperative biopsy findings or postoperative pathology. Patients with rectosigmoid schistosomiasis had a significantly higher CA-125 level and a larger proportion of these patients were at an early tumor stage(P = 0.003). Various morphological characteristics of schistosomiasis combined with rectosigmoid cancer could be found by colonoscopic examination: 46% were fungating mass polyps, 23%were congestive and ulcerative polyps, 23% were cauliflower-like masses, 8% were annular masses.Only 27% of the patients were diagnosed with rectal carcinoma preoperatively after the biopsy. Computed tomography(CT) scans showed thickened intestinal walls combined with linear and tram-track calcifications in 26 patients.CONCLUSION: Rectosigmoid carcinoma combined with schistosomiasis is associated with higher CA-125 values and early tumor stages. CA-125 and CT scans have a reasonable sensitivity for the accurate diagnosis. | Hao Feng Ai-Guo Lu Xue-Wei Zhao Ding-Pei Han Jing-Kun Zhao Lei Shi Tobias S Schiergens Serene ML Lee Wen-Peng Zhang Wolfgang E Thasler | 2015 | World Journal of Gastroenterology2015，21，23： | 6 |
| 7 | Receptor activator of NF-κB Ligand (RANKL) expression is associated with epithelial to mesenchymal transition in human prostate cancer cells显示文摘 | Valerie A Odero-Marah Ruoxiang Wang Gina Chu Majd Zayzafoon Jianchun Xu Chunmeng Shi Fray F Marshall Haiyen E Zhau Leland WK Chung | 2008 | Cell Research2008，18，8： | 6 |
| 8 | Assessment of deep groundwater over-exploitation in the North China Plain显示文摘A series of environmental—geological problems have been caused by over-exploitation of deep groundwater(i.e.,confined aquifer water) in the North China Plain.In order to better understand the status of deep groundwater over-exploitation and the resultant environmental—geological problems on a regional scale,the over-exploitation of groundwater has been assessed by way of the groundwater exploitation potential coefficient(i.e.,the ratio of exploitable amount of deep groundwater to current exploitation), cumulative land subsidence,and long-term average lowering rate of the groundwater table.There is a good correlation among the results calculated by the different methods.On a regional scale,deep groundwater has been over-exploited and there is no further exploitation potential under the current conditions.The groundwater exploitation degree index takes the exploitation in 2003 as the reference for the calculations, so the results mainly reflect the degree of current groundwater exploitation.The results of over-exploitation of deep groundwater obtained by land subsidence data and long-term average rate of depression of the water table mainly reflect environmental—geological problems caused by exploitation of deep groundwater. | Jiansheng Shi Zhao Wang Zhaoji Zhang Yuhong Fei Yasong Li Feng'e Zhang Jingsheng Chen Yong Qian | 2011 | Geoscience Frontiers2011，2，4： | 5 |
| 9 | A comparison of surgical efficacy between a 1.8-mm microincision and 3.2-mm and 5.5-mm incisions for phacoemulsification显示文摘Phacoemulsification is a commonly used surgical method in cataract surgery. This paper observes and compares the surgical efficacy of three incisions of different length for phacoemulsification to identify the optimal method for cataract surgery. Ninety patients were enrolled in the present study and divided into three groups. The 1.8-mm group received Bausch & Lomb MI60 foldable intraocular lens(IOL) implantation(n=30), 3.2-mm group received Bausch & Lomb Akreos AO foldable lens implantation(n=30), and 5.5-mm group received Alcon TYPE 05 rigid IOL implantation(n=30). Visual acuity, Oculyzer-based anterior segment analysis, and corneal endothelial cell count before surgery, and 3, 7, 30, and 90 d after surgery were recorded and compared. Pseudophakic accommodation three days, one week, one month, and three months after surgery was determined. Intraoperative ultrasound time and ultrasonic energy were recorded. It was finally concluded that for phacoemulsification with the same phaco tip, a 1.8-mm microincision can lead to quicker recovery of visual acuity, more stable astigmatism, and higher pseudophakic accommodation than conventional incision. | E Song Xin Li Ming-Chao Bi Hua Ren Dan Wang Zhi-Hua Cui Wei Yang Hui Shi Ya-Bin Sun | 2018 | International Journal of Ophthalmology(English edition)2018，11，3： | 4 |
| 10 | Identification of pathologic features associated with “ulcerative colitis-like” Crohn's disease显示文摘AIM: To identify pathologic features associated with this 'ulcerative colitis(UC)-like' subgroup of Crohn's disease(CD).METHODS: Seventeen subjects diagnosed as having UC who underwent proctocolectomy(RPC) from 2003-2007 and subsequently developed CD of the ileal pouch were identified. UC was diagnosed based on preoperative clinical, endoscopic, and pathologic studies. Eighteen patients who underwent RPC for UC within the same time period without subsequently developing CD were randomly selected and used as controls. Pathology reports and histological slides were reviewed for a wide range of gross and microscopic pathological features, as well as extent of disease. The demographics, gross description and histopathology of the resection specimens were reviewed and compared between the two groups. RESULTS: Patients with 'UC-like' CD were on average 13 years younger than those with 'true' UC(P < 0.01). More severe disease in the proximal involved region and active ileitis with/without architectural distortion were observed in 6 of 17(35%) and 7 of 17(41%) 'UC-like' CD cases, respectively, but in none of the 'true' UC cases(P < 0.05). Active appendicitis occurred in 8 of 16(50%) 'UC-like' CD cases but in only two(11%) 'true' UC cases(P < 0.05). Conspicuous lamina propria neutrophils were more specific for 'UClike' CD(76% vs 22%, P < 0.05). In addition, prominent lymphoid aggregates tended to be more common in 'UC-like' CD(P = 0.07). The 'true' UC group contained a greater number of cases with severe activity(78% vs 47%). Therefore, the features more commonly seen in 'UC-like' CD were not due to a more severe disease process. Crohn's granulomas and transmural inflammation in non-ulcerated areas were absent in both groups.CONCLUSION: More severe disease in the proximal involved region, terminal ileum involvement, active appendicitis, and prominent lamina propria neutrophils may be morphological factors associated with 'UC-like' CD. | Samuel D James Paul E Wise Tania Zuluaga-Toro David A Schwartz M Kay Washington Chanjuan Shi | 2014 | World Journal of Gastroenterology2014，20，36： | 4 |
| 11 | A Novel Model of Predicting Archie's Cementation Factor from Nuclear Magnetic Resonance(NMR) Logs in Low Permeability Reservoirs显示文摘The resistivity experimental measurements of core samples drilled from low permeability reservoirs of Ordos Basin,Northwest China,illustrate that the cementation factors are not agminate,but vary from 1.335 to 1.749.This leads to a challenge for the estimation of water and hydrocarbon saturation.Based on the analysis of Purcell equation and assumption that rock resistivity is determined by the parallel connection of numerous capillary resistances,a theoretical expression of cementation factor in terms of porosity and permeability is established.Then,cementation factor can be calculated if the parameters of porosity and permeability are determined.In the field application,porosity can be easily obtained by conventional logs.However,it is a tough challenge to estimate permeability due to the strong heterogeneity of low permeability reservoirs.Thus,the Schlumberger Doll Research(SDR)model derived from NMR logs has been proposed to estimate permeability.Based on the analysis of the theoretical expressions of cementation factor and SDR model,a novel cementation factor prediction model,which is relevant to porosity and logarithmic mean of NMR T2spectrum(T2lm),is derived.The advantage of this model is that all the input information can be acquired from NMR logs accurately.In order to confirm the credibility of the novel model,the resistivity and corresponding laboratory NMR measurements of 27 core samples are conducted.The credibility of the model is confirmed by comparing the predicted cementation factors with the core analyzed results.The absolute errors for all core samples are lower than 0.071.Once this model is extended to field application,the accuracy of water and hydrocarbon saturation estimation will be significantly improved. | Liang Wang Zhiqiang Mao Yujiang Shi Qin'e Tao Yumei Cheng Yong Song | 2014 | Journal of Earth Science2014，25，1： | 4 |
| 12 | Highly sensitive solar-blind deep ultraviolet photodetector based on graphene/PtSe_(2)/β-Ga_(2)O_(3)2D/3D Schottky junction with ultrafast speed显示文摘There is an emerging need for high-sensitivity solar-blind deep ultraviolet(DUV)photodetectors with an ultra-fast response speed.Although nanoscale devices based on Ga_(2)O_(3)nanostructures have been developed,their practical applications are greatly limited by their slow response speed as well as low specific detectivity.Here,the successful fabrication of two-/three-dimensional(2D/3D)graphene(Gr)/PtSe2/β-Ga_(2)O_(3)Schottky junction devices for high-sensitivity solar-blind DUV photodetectors is demonstrated.Benefitting from the high-quality 2D/3D Schottky junction,the vertically stacked structure,and the superior-quality transparent graphene electrode for effective carrier collection,the photodetector is highly sensitive to DUV light illumination and achieves a high responsivity of 76.2 mA/W,a large on/off current ratio of~105,along with an ultra-high ultraviolet(UV)/visible rejection ratio of 1.8×104.More importantly,it has an ultra-fast response time of 12µs and a remarkable specific detectivity of~1013 Jones.Finally,an excellent DUV imaging capability has been identified based on the Gr/PtSe2/β-Ga_(2)O_(3)Schottky junction photodetector,demonstrating its great potential application in DUV imaging systems. | Di Wu Zhihui Zhao Wei Lu Lukas Rogée Longhui Zeng Pei Lin Zhifeng Shi Yongtao Tian Xinjian Li Yuen Hong Tsang | 2021 | Nano Research2021，14，6： | 4 |
| 13 | Differential expression of meat quality and intramuscular fat deposition related genes in Hanjiang black pigs显示文摘 | Guofang Wu Xin'e Shi Jiping Zhou Lei Wang Yuefeng Li Chengchuang Song Aoqi Xiang Peiyue Dong Shiduo Sun | 2014 | Acta Biochimica et Biophysica Sinica2014，46，12： | 3 |
| 14 | Adjunctive MSCs enhance myelin formation by xenogenic oligodendrocyte precursors transplanted in the retina显示文摘 | Aileen Arriola Mary E Kiel Yufang Shi Randall D McKinnon | 2010 | Cell Research2010，20，6： | 3 |
| 15 | Perfectly Matched Layer for an Elastic Parabolic Equation Model in Ocean Acoustics显示文摘The perfectly matched layer(PML) is an effective technique for truncating unbounded domains with minimal spurious reflections. A fluid parabolic equation(PE) model applying PML technique was previously used to analyze the sound propagation problem in a range-dependent waveguide(Lu and Zhu, 2007). However, Lu and Zhu only considered a standard fluid PE to demonstrate the capability of the PML and did not take improved one-way models into consideration. They applied a [1/1] Padé approximant to the parabolic equation. The higher-order PEs are more accurate than standard ones when a very large angle propagation is considered. As for range-dependent problems, the techniques to handle the vertical interface between adjacent regions are mainly energy conserving and single-scattering. In this paper, the PML technique is generalized to the higher order elastic PE, as is to the higher order fluid PE. The correction of energy conserving is used in range-dependent waveguides. Simulation is made in both acoustic cases and seismo-acoustic cases. Range-independent and range-dependent waveguides are both adopted to test the accuracy and efficiency of this method. The numerical results illustrate that a PML is much more effective than an artificial absorbing layer(ABL) both in acoustic and seismo-acoustic sound propagation modeling. | XU Chuanxiu ZHANG Haigang PIAO Shengchun YANG Shi’e SUN Sipeng TANG Jun | 2017 | Journal of Ocean University of China2017，16，1： | 3 |
| 16 | MORN3:MEIG1的分子伴侣在小鼠生精细胞中的表达显示文摘哺乳动物精子发生由细胞发育和分化的精细过程组成。减数分裂基因1(MEG1)在调节精子发生过程中起着重要作用。为探讨MEIGl的作用机制,采用酵母双杂交筛选出可能与MEIG1发生作用的多个蛋白,OJMORN3蛋白。通过制备全长MORN3蛋白N端的特异性多克隆抗体,分别在体外和体内研究MORN3的表达和定位。免疫荧光染色转染CHO细胞显示,MORN3定位在整个包浆。体内实验证实25kDa的MORN3蛋白仅在小鼠睾丸组织中表达,且主要在出生后20天开始表达,即主要表达于精子发生的第三阶段生精细胞变态期。在从成年野生型小鼠分离的混合睾丸细胞的整个生精细胞变态期,MORN3均表达于顶体,在长形精子期该蛋白同时也在精子领表达。在Meig—J基因敲除小鼠中,MORN3总体表达水平和在顶体中的定位没有改变,但在精子领的表达显著降低。以上研究表明MORN3作为MEIGl蛋白的分子伴侣,可能是精子发生过程的另一个重要调节因子。 | Ling Zhang Xue-Jun Shang Hong-Fei Li Yu-Qin Shi Wei Li Maria E Teves Zhi-Qiong Wang Gao-Feng Jiang Shi-Zhen Song Zhi-Bing Zhang | 2015 | Asian Journal of Andrology2015，17，1： | 3 |
| 17 | Construction and Testing of a Primary Microsatellite Database of Major Rice Varieties in China显示文摘Sixty-three major inbred varieties and parental lines of major F1 hybrids used in the commercial rice production in China were assayed with rice microsatellites screened in a previous study and additional microsatellites on four chromosomes. A set of 24 markers was selected and proposed for its application in the variety identification of rice, which are distributed on all the 12 rice chromosomes with 2 markers on each chromosome. The 63 major varieties and parental lines, as well as 41 major F1 hybrids, were genotyped with the markers. Alleles detected in each line at each marker locus were verified. By matching marker genotypes of corresponding F1, maternal and paternal lines of hybrid rice, high reliability of the maternal lines was verified, data on the paternal lines were modified, and a false hybrid was removed. A database containing genotype data of 103 major rice varieties and parental lines at the 24 marker loci was constructed and analyzed. | YING Jie-zheng SHI Yong-feng E Zhi-guo ZENG Rui-zhen CHEN Jie ZHU Zhi-wei ZHUANG Jie-yun | 2007 | Rice science2007，14，4： | 3 |
| 18 | Tracking of CFSE-labeled endothelial progenitor cells in laser-injured mouse retina显示文摘背景 Endothelial 祖先房间(EPC ) 移植是为 ischemic retinopathy 的有希望的治疗学的策略。当前的学习试图为与 5-(and-6 ) 追踪 EPC 建立一个简单、可靠、荧光灯的标记的方法在伤害激光的老鼠 retina.Methods EPC 的 -carboxyfluorescein diacetate succinimidyl 酉旨(CFSE ) 从人的脐的绳索血 mononuclear 房间被孤立,栽培,并且用 CFSE 的各种各样的集中标记。基于荧光紧张和房间形态学,有在 37 点的 5 mol/L CFSE 的 15 分钟孵化作为最佳的标记条件被选择。幸存能力和标记 CFSE 的 EPC 的 apoptosis 率被染色的 Trypan 蓝色和 Annexin V/PI 染色试金分别地测量。荧光显微镜学被用来在扩大文化时期期间观察标签稳定性。标记的 EPC 被移植进网膜的激光光致疑结伤害的 pigmented 老鼠的玻璃的洞。Evans 蓝 angiography 和完全装的视网膜被检验追踪用 5 mol/L CFSE 介绍了标记的标记的 cells.Results EPC 一块强烈草地荧光和维持的正常形态学没有在在被标记 2 天以后的幸存能力或 apoptosis 率的重要变化, 1 和 4 个星期。荧光紧张逐渐地在 4 个星期的结束在房间减少了。视网膜的 Evans 蓝 angiography 清楚地显示了网膜的毛细作用网络,荧光漏在伤害激光的老鼠模型在 photocoagulated 点附近被观察。在标记的 EPC 的移植以后的一个星期,荧光灯房间在 photocoagulated 损害附近被识别。在移植以后的四个星期,荧光灯像试管的结构在网膜的脉管的 networks.Conclusion EPC 被观察能被 CFSE 在 vitro 标记并且在 vivo 监视了至少 4 个星期,并且参予受伤网膜的容器的修理。 | SHI Hui YANG Wei CUI Zhi-hua LU Cheng-wei LI Xiao-hong LIANG Ling-ling SONG E | 2011 | Chinese Medical Journal2011，，5： | 3 |
| 19 | On a general theory for compressing process and aeroacoustics:linear analysis显示文摘三个互相联合的基本过程(砍,压缩,并且热)在一般液体运动,仅仅为压缩过程的一般明确的表达和它的子进程, aeroacoustics 的题目,以及他们砍的物理结合和热过程,到目前为止没到达一致。这种状况为各种各样的深入的复杂 multiprocess 流动诊断,最佳的配置设计,和流动 / 噪音控制引起了困难。作为向在充分非线性的政体的需要的明确的表达的第一步,这份报纸采用操作符因式分解方法重游基本进程和他们的分解的分析线性理论,特别压缩进程进的进一步的切开声学并且熵模式,在 1940 年代鈥 ? 980s 发展了。这里对待的流动是在与质量,外部身体力量,和热增加的任意的来源一起的一个无界的领域的可压缩、粘滞、进行热的多花采蜜的气体的小骚乱。以前的结果从而被修订并且延长到一个完全、统一的理论。理论为由澄清某些基本问题开发相应非线性的理论提供一个必要基础和珍贵指导,例如压缩进程和他们的管理方程的特征的典型变量的合适的选择。关键词纵(压缩) 进程 - 横过(砍) 进程 - 声学的模式 - 熵模式 - Aeroacoustics 工程被中国(2009CB724100 ) 的国家基本研究程序支持。 | E .Mao Y. P. Shi J. Z. Wu | 2010 | Acta Mechanica Sinica2010，26，3： | 2 |
| 20 | Researches on the distribution law of vector sound field in elastic wedge bottom显示文摘基于为计算健全向量的有弹性的寓言的方程方法,领域被学习了的方法。水里的向量领域和相应震波地被计算了为在有有弹性的楔底部的海洋的环境下文健全。为健全来源的不同频率和深度的健全领域分发上的效果被研究了,进底部有声能漏的结果表演,漏发生了的位置能被海洋深度的比率决定到波长,作为与正常相比模式理论。 | ZHANG Haigang PIAO Shengchun YANG Shi'e AN Xudong | 2011 | Chinese Journal of Acoustics2011，30，4： | 2 |
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