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| 1 | A novel approach of testability modeling and analysis for PHM systems based on failure evolution mechanism显示文摘Prognostics and health management (PHM) significantly improves system availability and reliability, and reduces the cost of system operations. Design for testability (DFT) developed concurrently with system design is an important way to improve PHM capability. Testability modeling and analysis are the foundation of DFT. This paper proposes a novel approach of testability modeling and analysis based on failure evolution mechanisms. At the component level, the fault progression-related information of each unit under test (UUT) in a system is obtained by means of failure modes, evolution mechanisms, effects and criticality analysis (FMEMECA), and then the failure-symptom dependency can be generated. At the system level, the dynamic attributes of UUTs are assigned by using the bond graph methodology, and then the symptom-test dependency can be obtained by means of the functional flow method. Based on the failure-symptom and symptom-test dependencies, testability analysis for PHM systems can be realized. A shunt motor is used to verify the application of the approach proposed in this paper. Experimental results show that this approach is able to be applied to testability modeling and analysis for PHM systems very well, and the analysis results can provide a guide for engineers to design for testability in order to improve PHM performance. | Tan Xiaodong Qiu Jing Liu Guanjun Lv Kehong Yang Shuming Wang Chao | 2013 | Chinese Journal of Aeronautics2013，26，3： | 14 |
| 2 | Reactivation of γ-globin expression through Cas9 or base editor to treat β-hemoglobinopathies显示文摘Dear Editor,Mutations in the β-globin gene,the essential component of adult hemoglobin(HbA;a2p2),results in either a production of aberrant sickle hemoglobin(HbS)leading to sickle cell disease(SCD)or an insufficient β-globin synthesis leading to β-thalassemia.These two major forms of β-hemoglobinopathies cause impaired erythropoiesis and life-threatening anemia.Clinical evidence has suggested that reaaivation of fetal γ-globin(HBG)gene expression which is normally silenced after birth by certain genetic mutations can ameliorate the clinical course of β-hemoglobinopathies. | Liren Wang Linxi Li Yanlin Ma Handan Hu Qi Li Yang Yang Wenbang Liu Shuming Yin Wei Li Bin Fu Ryo Kurita Yukio Nakamura Mingyao Liu Yongrong Lai Dali Li | 2020 | Cell Research2020，30，3： | 14 |
| 3 | Increasing targeting scope of adenosine base editors in mouse and rat embryos through fusion of TadA deaminase with Cas9 variants显示文摘 | Lei Yang Xiaohui Zhang Liren Wang Shuming Yin Biyun Zhu Ling Xie Qiuhui Duan Huiqiong Hu Rui Zheng Yu Wei Liangyue Peng Honghui Han Jiqin Zhang Wenjuan Qiu Hongquan Geng Stefan Siwko Xueli Zhang Mingyao Liu Dali Li | 2018 | Protein & Cell2018，9，9： | 13 |
| 4 | Assessing the numbers of SNPs needed to establish molecular IDs and characterize the genetic diversityof soybean cultivars derived from Tokachi nagaha显示文摘The development of a core set of SNP molecular markers that could be widely used in soybean genetic research would greatly facilitate research into the genetic diversity of soybean.We conducted an analysis of Tokachi nagaha and 137 of its descendant soybean cultivars using 4044 SNP markers with the goal of determining the appropriate number of single-nucleotide polymorphisms(SNPs)needed to construct unambiguous molecular IDs and characterize genetic diversity based on a genetic distance matrix correlation method.When the number of SNPs was held constant,the number of accession pairs that could be distinguished increased as the polymorphism informative content(PIC)value of the SNPs increased.A core panel of 20 selected SNPs from 11 linkage groups with a mean PIC value of 0.3703 and a range of 0.3640–0.3749 was able to identify almost all of the accession pairs in our study[9445 pairs(99.92%)].The eight accession pairs that could not be identified with this core SNP set all originated from the same province and some of them had the same parental cultivars.The molecular IDs of the 138 accessions were constructed using the core 20 SNPs.It is known that both the number of SNPs and PIC values should be considered when SNPs are selected for use in the analysis of genetic diversity.In this study,when the PIC value was 0.3460,the correlation coefficient between the genetic distance matrices associated with a panel of 200 SNPs and the total population was>0.800,indicating satisfactory correlation.Our high-accuracy,high-resolution core SNP panel for germplasm fingerprinting and our findings about assessing genetic diversity will likely markedly improve the management and utilization efficiency of soybean germplasm resources. | Zhangxiong Liu Jun Li Xuhong Fan Nang Myint Phyu Sin Htwe Shuming Wang Wen Huang Jiyu Yang Lili Xing Lijun Chen Yinghui Li Rongxia Guan Ruzhen Chang Dechun Wang Lijuan Qiu | 2017 | The Crop Journal2017，5，4： | 10 |
| 5 | A red water occurrence in drinking water distribution systems caused by changes in water source in Beijing, China: mechanism analysis and control measures显示文摘 | Xiaojian ZHANG Zilong MI Yang WANG Shuming LIU Zhangbin NIU Pinpin LU Jun WANG Junnong GU Chao CHEN | 2014 | Frontiers of Environmental Science & Engineering2014，8，3： | 7 |
| 6 | The temporal-spatial distribution and changes of dissolved oxygen in the Changjiang Estuary and its adjacent waters for the last 50 a显示文摘The Changjiang Estuary and its adjacent waters form one of the most important estuarine and coastal areas in China. Multi source and long-term data are assembled to examine the temporal-spatial distribution features of dissolved oxygen(DO) in the Changjiang Estuary and its adjacent waters for the past 50 a. The results show that the DO concentration in the surface of different seasons generally stays stable, while the DO concentration in winter displays a slight increase for the last 50 a. The DO average concentration in winter and spring varies from 7to 11 mg/L, and in summer and autumn from 6 to 8 mg/L. Hypoxic values first appear in May, and low DO value plume can be observed on the bottom in spring along coastal areas of Zhejiang and Fujian Provinces, China. In summer, the plume advances northward, and the hypoxic intensity of northern transects is much higher than southern transects. Until autumn, hypoxia areas fade away little by little, and completely disappear in winter.Within last 50 a, hypoxia in the Changjiang Estuary and its adjacent waters starts to appear in the 1980 s. Since2000, the degree of hypoxia has increased seriously and the distribution depth has become smaller. It is performed based on a large amount of historical data, and the research results will be of great significance to further study on the dynamic development of hypoxia around the Changjiang Estuary. | LU Wenhai XIANG Xianquan YANG Lu XU Yan LI Xiao LIU Shuming | 2017 | Acta Oceanologica Sinica2017，36，5： | 6 |
| 7 | Room-temperature continuous-wave electrically pumped InGaN/GaN quantum well blue laser diode directly grown on Si显示文摘Current laser-based display and lighting applications are invariably using blue laser diodes(LDs)grown on freestanding GaN substrates,which are costly and smaller in size compared with other substrate materials.1–3 Utilizing less expensive and large-diameter Si substrates for hetero-epitaxial growth of indium gallium nitride/gallium nitride(InGaN/GaN)multiple quantum well(MQW)structure can substantially reduce the cost of blue LDs and boost their applications.To obtain a high crystalline quality crack-free GaN thin film on Si for the subsequent growth of a blue laser structure,a hand-shaking structure was formed by inserting Al-composition step down-graded AlN/AlxGa1−xN buffer layers between GaN and Si substrate.Thermal degradation in InGaN/GaN blue MQWs was successfully suppressed with indium-rich clusters eliminated by introducing hydrogen during the growth of GaN quantum barriers(QBs)and lowering the growth temperature for the p-type AlGaN/GaN superlattice optical cladding layer.A continuous-wave(CW)electrically pumped InGaN/GaN quantum well(QW)blue(450 nm)LD grown on Si was successfully demonstrated at room temperature(RT)with a threshold current density of 7.8 kA/cm^(2). | Yi Sun Kun Zhou Meixin Feng Zengcheng Li Yu Zhou Qian Sun Jianping Liu Liqun Zhang Deyao Li Xiaojuan Sun Dabing Li Shuming Zhang Masao Ikeda Hui Yang | 2018 | Light(Science & Applications)2018，7，1： | 5 |
| 8 | Elemental Content in Brown Rice by Inductively Coupled Plasma Atomic Emission Spectroscopy Reveals the Evolution of Asian Cultivated Rice显示文摘The phylogenetic relationship for classification traits and eight mineral elements in brown rice(Oryza sativa L.) from Yunnan Province in China was carried out using microwave assisted digestion followed by inductively coupled plasma atomic emission spectroscopy,and the analytical procedures were carefully controlled and validated.In general,the results show that the mean levels of K,Ca,Mg,Fe and Cu in brown rice for 789 accessions of rice landraces was distinctly lower than that of improved cultivars.They further demonstrate that Ca plays an important role in the differentiation of subspecies indica-japonica,especially to enhance adaptation of cold stress,and that five mineral elements in brown rice enhance the eurytopicity from landrace to improved cultivar.Hierarchical cluster analysis,using average linkage from SPSS software based on eight mineral elements in brown rice,showed that Yunnan rice could be grouped into rice landrace and improved cultivar,with the rice landrace being further clustered into five subgroups,and that,interestingly,purple rice does not cluster with either of the groups.Our present data confirm that indica is the closest relative of late rice and white rice,and that they constitute rice landraces together,whereas japonica is the closest relatives of non-nuda,early-mid and glutinous rice.It is further shown that japonica,non-nuda,early-mid,glutinous,white and red rice might be more primitive than indica,nuda,late,non-glutinous and purple rice,respectively. | Yawen Zeng Luxiang Wang Juan Du Jiafu Liu Shuming Yang Xiaoying Pu Fenghui Xiao | 2009 | Journal of Integrative Plant Biology2009，51，5： | 4 |
| 9 | Effect of microstructure of Au80Sn20 solder on the thermal resistance TO56 packaged GaN-based laser diodes显示文摘Au80Sn20 alloy is a widely used solder for laser diode packaging.In this paper,the thermal resistance of Ga N-based blue laser diodes packaged in TO56 cans were measured by the forward voltage method.The microstructures of Au80Sn20 solder were then investigated to understand the reason for the difference in thermal resistance.It was found that the microstructure with a higher content of Au-rich phase in the center of the solder and a lower content of(Au,Ni)Sn phase at the interface of the solder/heat sink resulted in lower thermal resistance.This is attributed to the lower thermal resistance of Au-rich phase and higher thermal resistance of(Au,Ni)Sn phase. | Hao Lin Deyao Li Liqun Zhang Pengyan Wen Shuming Zhang Jianping Liu Hui Yang | 2020 | Journal of Semiconductors2020，41，10： | 4 |
| 10 | Sensor Optimization Selection Model Based on Testability Constraint显示文摘Sensor selection and optimization is one of the important parts in design for testability. To address the problems that the traditional sensor optimization selection model does not take the requirements of prognostics and health management especially fault prognostics for testability into account and does not consider the impacts of sensor actual attributes on fault detectability, a novel sensor optimization selection model is proposed. Firstly, a universal architecture for sensor selection and optimization is provided. Secondly, a new testability index named fault predictable rate is defined to describe fault prognostics requirements for testability. Thirdly, a sensor selection and optimization model for prognostics and health management is constructed, which takes sensor cost as objective function and the defined testability indexes as constraint conditions. Due to NP-hard property of the model, a generic algorithm is designed to obtain the optimal solution. At last, a case study is presented to demonstrate the sensor selection approach for a stable tracking servo platform. The application results and comparison analysis show the proposed model and algorithm are effective and feasible. This approach can be used to select sensors for prognostics and health management of any system. | YANG Shuming QIU Jing LIU Guanjun | 2012 | Chinese Journal of Aeronautics2012，25，2： | 4 |
| 11 | Fabrication of Nanoscale Step Height Structure Using Atomic Layer Deposition Combined with Wet Etching显示文摘The current techniques used for the fabrication of nanosteps are normally done by layer growth and then ion beam thinning. There are also extra films grown on the step surfaces in order to reduce the roughness. So the whole process is time consuming. In this paper, a nanoscale step height structure is fabricated by atomic layer deposition(ALD) and wet etching techniques. According to the traceable of the step height value, the fabrication process is controllable. Because ALD technology can grow a variety of materials, aluminum oxide(Al_2O_3) is used to fabricate the nanostep. There are three steps of Al_2O_3 in this structure including 8 nm, 18 nm and 44 nm. The thickness of Al_2O_3 film and the height of the step are measured by anellipsometer. The experimental results show that the thickness of Al_2O_3 film is consistent with the height of the step. The height of the step is measured by AFM. The measurement results show that the height is related to the number of cycles of ALD and the wet etching time. The bottom and the sidewall surface roughness are related to the wet etching time. The step height is calibrated by Physikalisch-Technische Bundesanstalt(PTB) and the results were 7.5±1.5 nm, 15.5±2.0 nm and 41.8±2.1 nm, respectively. This research provides a method for the fabrication of step height at nanoscale and the nanostep fabricated is potential used for standard references. | WANG Chenying YANG Shuming JING Weixuan REN Wei LIN Qijing ZHANG Yijun JIANG Zhuangde | 2016 | Chinese Journal of Mechanical Engineering2016，29，1： | 3 |
| 12 | Research on Critical Flow of Water under Supercritical Pressures in Nozzles显示文摘 | Yuzhou Chen Minfu Zhao Chunsheng Yang Keming Bi Kaiwen Du Shuming Zhang | 2012 | Journal of Energy and Power Engineering2012，6，2： | 3 |
| 13 | A Dual-Platform Laser Scanner for 3D Reconstruction of Dental Pieces显示文摘This paper presents a dual-platform scanner for dental reconstruction based on a three-dimensional(3D)laser-scanning method.The scanner combines translation and rotation platforms to perform a holistic scanning.A hybrid calibration method for laser scanning is proposed to improve convenience and precision.This method includes an integrative method for data collection and a hybrid algorithm for data processing.The integrative method conveniently collects a substantial number of calibrating points with a stepped gauge and a pattern for both the translation and rotation scans.The hybrid algorithm,which consists of a basic model and a compensation network,achieves strong stability with a small degree of errors.The experiments verified the hybrid calibration method and the scanner application for the measurement of dental pieces.Two typical dental pieces were measured,and the experimental results demonstrated the validity of the measurement that was performed using the dual-platform scanner.This method is effective for the 3D reconstruction of dental pieces,as well as that of objects with irregular shapes in engineering fields. | Shuming Yang Xinyu Shi Guofeng Zhang Changshuo Lv | 2018 | Engineering2018，4，6： | 3 |
| 14 | Ni/Pd-based ohmic contacts to p-GaN through p-InGaN/p^(+)-GaN contacting layers显示文摘Specific contact resistance to p-GaN was measured for various structures of Ni/Pd-based metals and thin(20-30 nm thick)p-InGaN/p^(+)-GaN contacting layers.The effects of surface chemical treatment and annealing temperature were ex-amined.The optimal annealing temperature was determined to be 550°C,above which the sheet resistance of the samples de-graded considerably,suggesting that undesirable alloying had occurred.Pd-containing metal showed~35%lower com-pared to that of single Ni.Very thin(2-3.5 nm thick)p-InGaN contacting layers grown on 20-25 nm thick p^(+)-GaN layers exhib-ited one to two orders of magnitude smaller values of compared to that of p^(+)-GaN without p-InGaN.The current density de-pendence of,which is indicative of nonlinearity in current-voltage relation,was also examined.The lowest achieved through this study was 4.9×10^(-5)Ω·cm^(2)@J=3.4 kA/cm^(2). | Minglong Zhang Masao Ikeda Siyi Huang Jianping Liu Jianjun Zhu Shuming Zhang Hui Yang | 2022 | Journal of Semiconductors2022，43，9： | 3 |
| 15 | Effect of inhomogeneous broadening on threshold current of GaN-based green laser diodes显示文摘The inhomogeneous broadening parameter and the internal loss of green LDs are determined by experiments and theoretical fitting. It is found that the inhomogeneous broadening plays an important role on the threshold current density of green LDs. The green LD with large inhomogeneous broadening even cannot lase. Therefore, reducing inhomogeneous broadening is a key issue to improve the performance of green LDs. | Yipeng Liang Jianping Liu Masao Ikeda Aiqin Tian Renlin Zhou Shuming Zhang Tong Liu Deyao Li Liqun Zhang Hui Yang | 2019 | Journal of Semiconductors2019，40，5： | 3 |
| 16 | Distribution of electric field and design of devices in GaN avalanche photodiodes显示文摘We have investigated the distribution of the electric field in p-i-n type and separate absorption and multiplication(SAM) type GaN avalanche photodiodes under different reverse bias values.We have also analyzed the influences of the parameters of each layer,including width and concentration,on the distribution of the electric field,especially on the breakdown voltage.It is found that a relatively high concentration of p-GaN(higher than 1×10 18 cm 3) and low carrier concentration of i-GaN(lower than 5×10 16 cm 3) are helpful to restrict the electric field and reduce the breakdown voltage.In a SAM(p-i-n-i-n) structure,a suitable choice should be made for the concentration and thickness of the intermediate n-GaN layer in order to decrease breakdown voltage and prevent the device from degenerating into a p-i-n structure.Finally,the optimized material parameters of each layer are proposed. | WU LiangLiang ZHAO DeGang DENG Yi JIANG DeSheng ZHU JianJun WANG Hui LIU ZongShun ZHANG ShuMing ZHANG BaoShun YANG Hui | 2012 | Science China(Physics,Mechanics & Astronomy)2012，55，4： | 2 |
| 17 | Tensile and Isothermal Fatigue Behaviors of Mg-12Gd-3Y-0.5Zr Alloy at High Temperature显示文摘Tensile and isothermal fatigue tests were carried out on an as-rolled Mg-12Gd-3Y-0.5Zr alloy and its heat-treated counterpart at different temperatures. The experimental results show that the ultimate tensile strengths of two alloys decrease very slowly with increasing temperature up to 200?C. The ultimate tensile strength of heat-treated Mg-12Gd-3Y-0.5Zr is slight lower than that of as-rolled counterpart; however, the fatigue strength of heat-treated alloy is higher. The mechanism of fatigue failure was investigated by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). It shows that cyclic slip combined with environmental effect may be the main crack initiation mechanism. | Xiaoming Yang Huajie Yang Fan Yang Shuming Yin Wei Wang Shouxin Li Qudong Wang | 2009 | Journal of Materials Science & Technology2009，25，6： | 2 |
| 18 | Haplotype-resolved genome of diploid ginger (Zingiber officinale) and its unique gingerol biosynthetic pathway显示文摘Ginger(Zingiber officinale),the type species of Zingiberaceae,is one of the most widespread medicinal plants and spices.Here,we report a high-quality,chromosome-scale reference genome of ginger‘Zhugen’,a traditionally cultivated ginger in Southwest China used as a fresh vegetable,assembled from PacBio long reads,Illumina short reads,and high-throughput chromosome conformation capture(Hi-C)reads.The ginger genome was phased into two haplotypes,haplotype 1(1.53 Gb with a contig N50 of 4.68 M)and haplotype 0(1.51 Gb with a contig N50 of 5.28 M).Homologous ginger chromosomes maintained excellent gene pair collinearity.In 17,226 pairs of allelic genes,11.9%exhibited differential expression between alleles.Based on the results of ginger genome sequencing,transcriptome analysis,and metabolomic analysis,we proposed a backbone biosynthetic pathway of gingerol analogs,which consists of 12 enzymatic gene families,PAL,C4H,4CL,CST,C3’H,C3OMT,CCOMT,CSE,PKS,AOR,DHN,and DHT.These analyses also identified the likely transcription factor networks that regulate the synthesis of gingerol analogs.Overall,this study serves as an excellent resource for further research on ginger biology and breeding,lays a foundation for a better understanding of ginger evolution,and presents an intact biosynthetic pathway for species-specific gingerol biosynthesis. | Hong-Lei Li Lin Wu Zhaoming Dong Yusong Jiang Sanjie Jiang Haitao Xing Qiang Li Guocheng Liu Shuming Tian Zhangyan Wu Bin Wu Zhexin Li Ping Zhao Yan Zhang Jianmin Tang Jiabao Xu Ke Huang Xia Liu Wenlin Zhang Qinhong Liao Yun Ren Xinzheng Huang Qingzhi Li Chengyong Li Yi Wang Baskaran Xavier-Ravi Honghai Li Yang Liu Tao Wan Qinhu Liu Yong Zou Jianbo Jian Qingyou Xia Yiqing Liu | 2021 | Horticulture Research2021，8，1： | 2 |
| 19 | Flotation of copper oxide minerals:A review显示文摘Copper oxide minerals are important copper resources,which include malachite,azurite,chrysocolla,cuprite,etc.Flotation is the most widely used method for the enrichment of copper oxide minerals in the mineral processing industry.In this paper,the surface properties of copper oxide minerals and their effects on the mineral flotation behavior are systematically summarized.The flotation methods of copper oxide minerals and the interaction mechanism with reagents are reviewed in detail.Flotation methods include direct flotation(using chelating reagents or a fatty acid as collector),sulfidization flotation(using xanthate as collector),and activation flotation(using chelating reagents,ammonium/amine salts,metal ions,and oxidant for activation).An effective way to realize efficient flotation of copper oxide minerals is to increase active sites on the surface of copper oxide minerals to enhance the interaction of collector with the mineral surface.Besides,various perspectives for further investigation on the efficient recovery of copper oxide minerals are proposed. | Qicheng Feng Wenhang Yang Shuming Wen Han Wang Wenjuan Zhao Guang Han | 2022 | International Journal of Mining Science and Technology2022，32，6： | 2 |
| 20 | Ultrastable and colorful afterglow from organic luminophores in amorphous nanocomposites:Advanced anti-counterfeiting and in vivo imaging application显示文摘Special attention has been paid to the organic afterglow materials(OAM)for their fascinating properties.However,poor stability at air and complicated structure design hinder the development of OAM.Herein,sol-gel,a facile and simple technique,is employed to synthesize a series of organic/inorganic hybrid nanocomposites(N1/SiO2,N2/SiO2,and N3/SiO2)by covalently linking three common aryl imides with crosslinked silica skeleton.These nanomaterials show excitation wavelength-dependent and colorful(yellow,red and green)afterglow of organic imides with long lifetime up to 1.1 s at air.Interestingly,the ultralong phosphorescence is ultrastable under various conditions:water,high temperature,UV irradiation and in vivo,due to the protection of inorganic silica.In particularly,heating to 500℃does not quench the afterglow of organic luminophore in nanocomposites,but forms new ultralong phosphorescence originated from space-conjugation of silica and carbonyl.The afterglow nanomaterials display huge advantages in the applications of advanced anti-counterfeiting and bioimaging. | Qiuqin Huang Heqi Gao Shuming Yang Dan Ding Zhenghuan Lin Qidan Ling | 2020 | Nano Research2020，13，4： | 2 |
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