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| 1 | Disulfiram thermosensitive in-situ gel based on solid dispersion for cataract显示文摘To improve the corneal permeability and water-solubility of disulfiram(DSF), which is an ocular drug for cataract, P188 was selected as a matrix to prepare solid dispersion of DSF(DSF SD) by hot melt method. The DSF SD was characterized by DSC, XRD, and IR, and the results suggested that DSF was amorphous in DSF SD. The DSF SD was added to borate buffer solution(BBS) contained 20% poloxamer P407 and 1.2% poloxamer P188 to form in-situ gel. In vitro and in vivo experiments revealed that DSF SD combined with in-situ gel(DSF SD/in-situ gel) increased the residence time and the amount of DSF penetrated through the corneal. The pharmacodynamics studies exhibited DSF SD/in-situ gel delayed the development of selenium-induced cataract at some content. These results investigated that DSF SD/in-situ gel as a drug delivery system can improve DSF ocular permeability. | Chunjuan Zhang Tonghua Xu Donglei Zhang Wei He Siling Wang Tongying Jiang | 2018 | Asian Journal of Pharmaceutical Sciences2018，13，6： | 3 |
| 2 | Super-ferric Dipole Prototype for Super-FRS of FAIR显示文摘 | Yuan Ping Ma Lizhen H. Leibrock Zhang Xiaoqi Zhang Bin Yao Qinggao Wu Weiyue Wang Qiuliang Wu Wei Wu xi Yang Tongjun Cuo Beilei Han Shaofei He Yuan Zhang Siling | 2009 | 近代物理研究所和兰州重离子加速器实验室年报:英文版2009，，1： | 1 |
| 3 | LRRK2 R1398H polymorphism is associated with decreased risk of Parkinson’s disease in a Han Chinese population显示文摘 | Ling Chen Sile Zhang Yanmei Liu Hua Hong Hongxuan Wang Yifan Zheng Hongyan Zhou Jie Chen Wenbiao Xian Yuemei He Jinru Li Zhuolin Liu Zhong Pei Jinsheng Zeng | 2010 | Parkinsonism and Related Disorders2010，，4： | 1 |
| 4 | Maturity Assessment of the Lower Cambrian and Sinian Shales Using Multiple Technical Approaches显示文摘The Lower Cambrian Niutitang and Sinian Doushantuo shales are the most important and widespread source rocks and target layers in South China. Reliable data of the thermal maturity of organic matter(OM) is widely used to assess hydrocarbon generation and is a key property used in determining the viability and hydrocarbon potential of these new shales. Nevertheless, traditional thermal maturity indicators are no longer suited to the vitrinite-lack marine shales. This study aims to combine high throughput Raman and infrared spectroscopy analysis to confirm and validate the thermal maturity in comparison with the bitumen reflectance(R_(b)). Raman parameters such as the differences between the positions of the two bands(V_(G)–V_(D)) are strong parameters for calculating the thermal maturity in a large vitrinite reflectance(R_(o)) ranging from 1.60% to 3.80%. The infrared spectroscopy analysis indicates that the aromatic C=C bands and CH_(2)/CH_(3) aliphatic groups both are closely correlated with thermal maturity. The calculated R_(o) results from Raman and infrared spectroscopy are in strong coincidence with the R_(b). The relationships between R_(b) and pore volumes/surface areas(calculated from N_(2) adsorption) indicate that the sample with R_(b) of 3.40% has the lowest pore volumes and surface areas. Focused ion beam scanning electron microscopy(FIB-SEM) observations of OM pores indicate that R_(o) of approximately 3.60% may be an upper limit for OM porosity development. Obviously, kerogen Raman and infrared spectroscopy can indicate methods for reducing the risk in assessing maturity with practical, low-cost accurate results. Exploration of shale gas in the high maturity(>3.40%–3.60%) region carries huge risks. | Wei Yang Sheng He Gangyi Zhai Ze Tao Xiaoqing Yuan Sile Wei | 2021 | Journal of Earth Science2021，32，5： | 0 |
| 5 | Estimation of inverse Compton peak frequency for 4FGL Blazars显示文摘This study uses a parabolic equation to fit the Inverse Compton (IC) spectral component of 3743 blazars (794 FSRQs,1432 BLLacs,and 1517 BCUs) from the 4FGL-DR3 catalog.Some mutual correlations are investigated,and a Bayesian classification is performed to the IC peak frequencies.Our analyses draw the following conclusions:(1) The Bayesian classification shows two components with a dividing boundary of log(v_(p)^(IC)/Hz)pIC=22.9.Therefore,the 3743 blazars are divided into low IC peak frequency(LCP) blazars and high IC peak frequency (HCP) blazars.(2) A strong linear correlation exists between IC peak frequency(logv_(p)^(IC)) and γ-ray photon spectral index (Γ).The IC peak frequency can be estimated by an empirical relation logv_(p)^(IC)=–4.5·Γ+32.8 for BL Lacs and logv_(p)^(IC)=4.0+31.4pICfor FSRQs,which is consistent with the result by Abdo et al.(3) The ICspectral curvature and IC peak frequency are not as closely related as the synchrotron curvature and the synchrotron peak frequency.(4) An anti-correlation exists between IC peak frequency and IC peak luminosity,implying that as the IC peak frequency in the γ-ray band decreases,the source becomes more luminous.The beaming effect is stronger for the source with a lower IC peak frequency.(5) Positive correlations exist between IC and synchrotron components for both peak frequencies and peak fluxes,but no clear correlation exists between IC curvature and synchrotron curvature. | JiangHe Yang JunHui Fan Yi Liu ManXian Tuo ZhiYuan Pei WenXin Yang YuHai Yuan SiLe He ShengHui Wang XiaoHai Qu YueLian Zhang JianJun Nie XiuHui Chen | 2023 | Science China(Physics,Mechanics & Astronomy)2023，66，4： | 0 |
| 6 | Measurements of 21.6° C-type Dipoles for CSRm Injection Beam Line显示文摘Three C-type dipoles, which will be arranged in the CSRm injection beam line, have been measured by using CSR Long Coil Magnet Measurement System and NMR. The parameters of the three dipoles are listed in Table 1. When testing the local transmit function (local exciting curve), the NMR probe is laid in the center of the magnet to | He Yuan, Xiong Hui, Han Shaofei, Liu Weijun, Ma Lizhen, Yuan Ping, Wang Yue and Zhang Siling | 2002 | 近代物理研究所和兰州重离子加速器实验室年报:英文版2002，，1： | 0 |
| 7 | Field Mapping Measurement of CSRe Dipoles显示文摘The field mapping measurement of 16 C-type CSRe dipoles was measured by using Hall Sensor in last year. The main parameters of the dipoles for CSRe are listed in Table 1. The hall sensor mapping system of HIRFL- CSR consists of a single hall sensor, mapping bench and data acquirement system. The hall sensor is produced by AREPOC Co. Its absolute measurement errors are below 5×10-5 T after calibrated with NMR. | Han Shaofei, He Yuan, Yao Qinggao, Ma Lizhen,Yuan Ping and Zhang Siling | 2005 | 近代物理研究所和兰州重离子加速器实验室年报:英文版2005，，1： | 0 |
| 8 | Measurements of CSRm Quadrupoles显示文摘There are 30 quadruples in main ring of CSR. Its parameters are listed in Table 1. All of them were manufactured and tested last yeal. | He Yuan, Liu Weijun, Zhang Bin, Han Shaofei, Ma Lizhen, Su Yalong Zhang Siling and Yuan Ping | 2003 | 近代物理研究所和兰州重离子加速器实验室年报:英文版2003，，1： | 0 |
| 9 | Measurement of Reproducibility for CSRm Dipoles显示文摘The reproducibility of CSRm dipoles is an important factor to be considered in CSR project. There have seventeen dipoles in the cooling storage main ring (CSRm). The reproducibility of seventeen dipoles should be better than 2×10^-4 at the optimum magnetic held. The longest in the seventeen dipoles is chosen as the reference magnet;. The reproducibility is derived | Su Yalong, He Yuan, Yuan Ping, Ma Lizhen, Liu Weijun, Han Shaofci and Zhang Siling | 2003 | 近代物理研究所和兰州重离子加速器实验室年报:英文版2003，，1： | 0 |
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