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| 1 | Recent advances and applications of machine learning in solidstate materials science显示文摘One of the most exciting tools that have entered the material science toolbox in recent years is machine learning.This collection of statistical methods has already proved to be capable of considerably speeding up both fundamental and applied research.At present,we are witnessing an explosion of works that develop and apply machine learning to solid-state systems.We provide a comprehensive overview and analysis of the most recent research in this topic.As a starting point,we introduce machine learning principles,algorithms,descriptors,and databases in materials science.We continue with the description of different machine learning approaches for the discovery of stable materials and the prediction of their crystal structure.Then we discuss research in numerous quantitative structure–property relationships and various approaches for the replacement of first-principle methods by machine learning.We review how active learning and surrogate-based optimization can be applied to improve the rational design process and related examples of applications.Two major questions are always the interpretability of and the physical understanding gained from machine learning models.We consider therefore the different facets of interpretability and their importance in materials science.Finally,we propose solutions and future research paths for various challenges in computational materials science. | Jonathan Schmidt Mário R.G.Marques Silvana Botti Miguel A.L.Marques | 2019 | npj Computational Materials2019，，1： | 49 |
| 2 | Role of Hox genes in stem cell differentiation显示文摘Hox genes are an evolutionary highly conserved gene family. They determine the anterior-posterior body axis in bilateral organisms and influence the developmental fate of cells. Embryonic stem cells are usually devoidof any Hox gene expression, but these transcription factors are activated in varying spatial and temporal patterns defining the development of various body regions. In the adult body, Hox genes are among others responsible for driving the differentiation of tissue stem cells towards their respective lineages in order to repair and maintain the correct function of tissues and organs. Due to their involvement in the embryonic and adult body, they have been suggested to be useable for improving stem cell differentiations in vitro and in vivo. In many studies Hox genes have been found as driving factors in stem cell differentiation towards adipogenesis, in lineages involved in bone and joint formation, mainly chondrogenesis and osteogenesis, in cardiovascular lineages including endothelial and smooth muscle cell differentiations, and in neurogenesis. As life expectancy is rising, the demand for tissue reconstruction continues to increase. Stem cells have become an increasingly popular choice for creating therapies in regenerative medicine due to their self-renewal and differentiation potential. Especially mesenchymal stem cells are used more and more frequently due to their easy handling and accessibility, combined with a low tumorgenicity and little ethical concerns. This review therefore intends to summarize to date known correlations between natural Hox gene expression patterns in body tissues and during the differentiation of various stem cells towards their respective lineages with a major focus on mesenchymal stem cell differentiations. This overview shall help to understand the complex interactions of Hox genes and differentiation processes all over the body as well as in vitro for further improvement of stem cell treatments in future regenerative medicine approaches. | Anne Seifert David F Werheid Silvana M Knapp Edda Tobiasch | 2015 | World Journal of Stem Cells2015，7，3： | 10 |
| 3 | Head-to-head comparison of N-terminal pro-brain natriuretic peptide, brain natriuretic peptide and N-terminal pro-atrial natriuretic peptide in diagnosing left ventricular dysfunction显示文摘 | Angelika Hammerer-Lercher Elke Neubauer Silvana Müller Otmar Pachinger Bernd Puschendorf Johannes Mair | 2001 | Clinica Chimica Acta2001，，2： | 2 |
| 4 | Expression analysis of the exo-fl-l,3-glucanse from the mycoparasitic fungus Trichoderma asperellura显示文摘 | C6sar M M Andrei S S Silvana P D S | 2010 | Microbiological Research2010，165，1： | 1 |
| 5 | Peripheral Blood Mononuclear Cells Immunophenotyping in Pulmonary Tuberculosis Patients before and after Treatment显示文摘 | Warly Barcelos Olindo Assis Martins‐Filho Tania Mara Pinto Dabés Guimar?es Márcio Hamilton Prostzner Oliveira Silvana Spíndola‐de‐Miranda Beatriz Nascimento Carvalho Vicente de Paulo Coelho Peixoto Toledo | 2006 | Microbiology and Immunology2006，，： | 1 |
| 6 | A survey on parent child confiict resolution: intrafamily violence in Italy 显示文摘 | Bardi M Silvana M Borgognini Tarli | 2001 | Child Abuse & Neglect2001，6，： | 1 |
| 7 | Sterol composi- tion of some mediterranean green algae 显示文摘 | Lorenzo D N Silvana M Luciano M | 1982 | Phytochemis- try1982，21，8： | 1 |
| 8 | Lobar lung transplantation from deceased donors: A systematic review显示文摘AIM To systematically review reports on deceased-donor-lobar lung transplantation(dd LLTx) and uniformly describe sizematching using the donor-to-recipient predicted-total lung-capacity(pT LC) ratio. METHODS We set out to systematically review reports on ddL LTx and uniformly describe size matching using the donorto-recipient pT LC ratio and to summarize reported oneyear survival data of ddL LTx and conventional-LTx. We searched in Pub Med, CINAHL via EBSCO, Cochrane Database of Systematic Reviews via Wiley(CDSR),Database of Abstracts of Reviews of Effects via Wiley(DARE), Cochrane Central Register of Controlled Trials via Wiley(CENTRAL), Scopus(which includes EMBASE abstracts), and Web of Science for original reports on ddL LTx. RESULTS Nine observational cohort studies reporting on 301 ddL LTx met our inclusion criteria for systematic review of size matching, and eight for describing one-year-survival. The dd LLTx-group was often characterized by high acuity;however there was heterogeneity in transplant indications and pre-operative characteristics between studies. Data to calculate the pT LC ratio was available for 242 ddL LTx(80%). The mean pT LCratio before lobar resection was1.25 ± 0.3 and the transplanted pT LCratio after lobar resection was 0.76 ± 0.2. One-year survival in the ddL LTxgroup ranged from 50%-100%, compared to 72%-88%in the conventional-LTx group. In the largest study ddL LTx(n = 138) was associated with a lower one-year-survival compared to conventional-LTx(n = 539)(65.1% vs84.1%, P < 0.001). CONCLUSION Further investigations of optimal donor-to-recipient size matching parameters for ddL LTx could improve outcomes of this important surgical option. | Michael Eberlein Robert M Reed Mayy Chahla Servet Bolukbas Amy Blevins Dirk Van Raemdonck Alessia Stanzi Ilhan Inci Silvana Marasco Norihisa Shigemura Clemens Aigner Tobias Deuse | 2017 | World Journal of Transplantation2017，7，1： | 1 |
| 9 | Imatinib resistance in multidrug-resistant K562 human leukemic cells显示文摘 | Yanina Assef Fernanda Rubio Georgina Coló Silvana del Mónaco Mónica A. Costas Basilio A. Kotsias | 2008 | Leukemia Research2008，，5： | 1 |
| 10 | Somatic embryogenesis and esculin formation in calli and embryoids from bark explants of Aesculus nippocastanum L 显示文摘 | PAOLA G ANNA M C SILVANA C | 1996 | Plant Science1996，119，12： | 1 |
| 11 | DNA-protein cross-links and sister chromatid exchanges induced by dimethylarsinic acid in human fibroblasts cells 显示文摘 | SILVANA A M CLAUDIA A G FERNANDO N D | 2005 | Mutat Res2005，581，12： | 1 |
| 12 | Twenty years research in cholinesterase biosensors: from basie researeh to practical ap- plieations显示文摘 | SILVANA A JEAN-LOUIS M | 2006 | Biomolecular Engineering2006，23，： | 1 |
| 13 | An unusual cause of diastolic mitral regurgitation as a result of sterile perforation of the mitraI valve显示文摘 | Marcus A Silvana M Johannes B | 2003 | J Am Soc Echocardiography2003，16，1： | 1 |
| 14 | Comparative genomic analysis,diversity and evolution of two KIR haplotypes A and B显示文摘 | Annalise M M Jerzy K K Silvana G | 2004 | Gene2004，335，5： | 1 |
| 15 | Soy protein isolation components and their interactions 显示文摘 | Silvana P Anon M C | 1995 | Journal of Agricultural and Food Chemistry1995，43，： | 1 |
| 16 | Experimental investigation on the combustion process in a spark ignition optically accessible engine fueled with methane/hydrogen blends 显示文摘 | SILVANA D ] PAOLO S BIANCA M V | 2014 | International journal of hydrogen energy2014，39，18： | 1 |
| 17 | Effects of prostacyclin on the early inflammatory response in patients with traumatic brain injury-a randomised clinical study显示文摘 | Marie Rodling Wahlstr?m Magnus Olivecrona Clas Ahlm Anders Bengtsson Lars-Owe D Koskinen Silvana Naredi Magnus Hultin | 2014 | SpringerPlus2014，，： | 1 |
| 18 | Identification of trait-improving quantitative trait loci alleles from a wild rice relative,Oryza rufipogon显示文摘 | Xiao J H Li J M Silvana G | 1998 | Genetics1998，150，： | 1 |
| 19 | A survey on parent-child conflict resolution: intrafamily violence in Italy 显示文摘 | Bardi M Silvana M Borgognini-Tarli | 2001 | Child Abuse Negl2001，25，6： | 1 |
| 20 | Amoxicillin-loaded polyethylcyanoacrylate nanoparticles: Influence of PEG coating on the particle size, drug release rate and phagocytic uptake显示文摘 | Giacomo F Mariano L Silvana M | 2001 | Biomaterials2001，22，： | 1 |
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