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| 1 | Anti-tumor activity of wogonin, an extract from Scutellaria baicalensis, through regulating different signaling pathways显示文摘Wogonin is a plant flavonoid compound extracted from Scutellaria baicalensis(Huang-Qin or Chinese skullcap) and has been studied thoroughly by many researchers till date for its anti-viral, anti-oxidant, anti-cancerous and neuro-protective properties. Numerous experiments conducted in vitro and in vivo have demonstrated wogonin's excellent tumor inhibitory properties. The anticancer mechanism of wogonin has been ascribed to modulation of various cell signaling pathways, including serine-threonine kinase Akt(also known as protein kinase B) and AMP-activated protein kinase(AMPK) pathways, p53-dependent/independent apoptosis, and inhibition of telomerase activity. Furthermore, wogonin also decreases DNA adduct formation with a carcinogenic compound 2-Aminofluorene and inhibits growth of drug resistant malignant cells and their migration and metastasis, without any side effects. Recently, newly synthesized wogonin derivatives have been developed with impressive anti-tumor activity. This review is the succinct appraisal of the pertinent articles on the mechanisms of anti-tumor properties of wogonin. We also summarize the potential of wogonin and its derivatives used alone or as an adjunct therapy for cancer treatment. Furthermore, pharmacokinetics and side effects of wogonin and its analogues have also been discussed. | Do Luong Huynh Neelesh Sharma Amit Kumar Singh Simrinder Singh Sodhi ZHANG Jiao-Jiao Raj Kumar Mongre Mrinmoy Ghosh Nameun Kim Yang Ho Park Dong Kee Jeong | 2017 | Chinese Journal of Natural Medicines2017，15，1： | 32 |
| 2 | 渤海海冰工程设计参数分布显示文摘利用渤海历史资料建立由气温、水温、冰期和冰厚表达平整冰层温度、盐度、密度的垂直剖面,进而获得冰的孔隙率垂直剖面。在此基础上通过渤海冰力学参数同孔隙率的试验关系计算出相应冰层峰值压缩强度、峰值弯曲强度、峰值剪切强度和弹性模量。将渤海历史资料归纳的冬季气温分布、水温分布和不同重现期冰厚度分布资料放入渤海1/6经度和1/6纬度的网格内,从而获得渤海不同重现期平整冰层的物理和力学参数分布。作为实例,给出渤海25、50、100年重现期的平整冰层设计厚度分布、压缩强度分布、弯曲强度分布、剪切强度分布和弹性模量分布。 | 李志军 Devinder S Sodhi 卢鹏 | 2006 | 工程力学2006，23，6： | 17 |
| 3 | 基于海冰物理和力学参数的渤海冰工程分区显示文摘根据渤海海冰物理和力学参数分布建立渤海海冰工程分区。其特点是将作用到相同直径或宽度的直立结构物上冰的作用力范围相同的区域划分为同一分区内,因此不同重现期设计冰厚度和峰值压缩强度之积作为区划指标。为了获得不同重现期渤海海冰物理和力学性质参数,利用渤海历史资料建立用气温、水温、冰期和冰厚表达非变形平整冰层和冰样温度、盐度、密度的关系,进而获得冰的孔隙率;利用渤海海冰单轴压缩强度同孔隙率的试验关系计算相应峰值压缩强度;然后发展渤海不同重现期平整冰层物理和力学参数的平面分布。在此基础上以新区划指标做不同重现期的海冰工程分区。作为新区划的实例,给出25、50、100年重现期的渤海海冰工程分区。 | 李志军 卢鹏 Devinder S Sodhi | 2004 | 水科学进展2004，15，5： | 6 |
| 4 | Soil aggregation and distribution of carbon and nitrogen in different fractions under long-term application of compost in rice–wheat system显示文摘 | G.P.S. Sodhi V. Beri D.K. Benbi | 2008 | Soil & Tillage Research2008，，2： | 2 |
| 5 | Powder method for detecting latent fingerprints: a review显示文摘 | G.S. Sodhi J. Kaur | 2001 | Forensic Science International2001，，3： | 2 |
| 6 | Ranibizumab in diabetic macular edema显示文摘By 2050 the prevalence of diabetes will more than triple globally,dramatically increasing the societal and financial burden of this disease worldwide.As a consequence of this growth,it is anticipated that there will be a concurrent rise in the numbers of patients with diabetic macular edema(DME),already among the most common causes of severe vision loss worldwide.Recent available therapies for DME target the secreted cytokine,vascular endothelial growth factor(VEGF).This review focuses on the treatment of DME using the first humanized monoclonal antibody targeting VEGF that has been Food and Drug Administrationapproved for the use in the eye,ranibizumab(Lucentis). | Claudia Krispel Murilo Rodrigues Xiaoban Xin Akrit Sodhi | 2013 | World Journal of Diabetes2013，4，6： | 2 |
| 7 | Prevalence of H elicobacter pylori infection and the effect of its eradication on symptoms of functional dyspepsia in K ashmir, I ndia显示文摘 | Jaswinder Singh Sodhi Gul Javid Showkat Ali Zargar Syed Tufail Altaf Shah Bashir Ahmad Khan Ghulam Nabi Yattoo Ghulam Mohamad Gulzar Mushtaq Ahmad Khan Mohd Iqbal Lone Riyaz u Saif Shaheena Parveen Abid Shoukat | 2013 | J Gastroenterol Hepatol2013，，5： | 2 |
| 8 | Integrated Design Environment for DC/DC Converter FET Optimization显示文摘 | Ritu Sodhi | 1999 | IEEE1999，，： | 1 |
| 9 | Towards Modeling of Assembly of ProductDesign显示文摘 | Rajnect Sodhi Toshua U Turner | 1994 | CAD1994，26，2： | 1 |
| 10 | MAPK and Akt act cooperatively but independently on hypoxia inducible factor-1α in rasV12 upregulation of VEGF显示文摘 | Sodhi A Montaner S Miyazaki H | 2001 | Biochem Bioph Res Co2001，287，1： | 1 |
| 11 | Hypoxia and high glucose cause exaggerated mesangial cell growth and collagen synthesis:role of osteopontin显示文摘 | Sodhi C P Phadke S A Batlle D | 2001 | Am J Physiol Renal Physiol2001，280，4： | 1 |
| 12 | Position of a sigmoid colon in right iliac fossa in children:A retrospective study显示文摘 | Saxena AK Sodhi KS Tirumani S | 2011 | J Indian Assoc Pediatr Surg2011，16，3： | 1 |
| 13 | Involvement of mitogen-activated protein kinases in the signal transduction pathway of bone marrow derived macrophage activation in response to in vitro treatment with thymosin alpha 1 显示文摘 | Sodhi A Panl S | 2002 | Int Immunopharmacol2002，2，1： | 1 |
| 14 | Researchers' Perspectives on Sup- ply Chain Risk Management 显示文摘 | Sodhi M S Son B G Tang C S | 2012 | Production and Operations Man- agement2012，21，1： | 1 |
| 15 | Relationship Between Daytime Variability of Blood Pressure or Ocular Perfusion Pressure and Glaucomatous Visual Field Progression显示文摘 | Sodhi PK Chawla AK | 2015 | Am J Ophthalmol2015，160，4： | 1 |
| 16 | Endothelial-specific CYP4A2 overexpression leads to renal injury and hy- pertension via increased production of 20-HETE 显示文摘 | Inoue K Sodhi K Puri N | 2009 | Am J Physiol Renal Physiol2009，297，4： | 1 |
| 17 | Efficacy and safety of brimonidine, dorzolamide and latanoprost as adjunctive therapy in primary open angle glaucoma 显示文摘 | Sodhi PK Pandey RM Ratan SK | 2003 | Int J Clin Pract2003，57，10： | 1 |
| 18 | The kaposi′s savcomaassociated hevpes vives G Protein crupled receptor up regulates vascular endothelial growth factor expression and secretion thrugh mitogen-activated protein kinase and P38 Pathways acting on hyponia-inducible factor 1 alpha显示文摘 | Sodhi A Montaner S Patel V | 2000 | Cancer Res2000，60，： | 1 |
| 19 | Role of tissue harmonic imaging in focal hepatic lesions: co -mparison with conven-tional sonography显示文摘 | Sodhi K S Sidhu R Gulati M | 2005 | J Gastroenterol Hepatol2005，20，10： | 1 |
| 20 | Characteristics of acetylated starches prepared using starches separated from different rice cultivars显示文摘 | SODHI N S SINGH N | 2005 | Journal of Food Engineering2005，70，1： | 1 |
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