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| 1 | Age distribution,polyps and rectal cancer in the Egyptian population-based cancer registry显示文摘AIM:To describe the clinical and epidemiologic profiles of the disease and to compare the findings with those generated from the previous hospital-based studies.METHODS:The Gharbiah cancer registry is the only population-based cancer registry in Egypt since 1998.We analyzed the data of all colorectal cancer patients included in the registry for the period of 1999-2007.All medical records of the 1364 patients diagnosed in Gharbiah during the study period were retrieved and the following information abstracted:age,residence,diagnosis date,grade,stage,topology,clinical characteristics,and histology variables.Egyptian census data for 1996 and 2006 were used to provide the general population's statistics on age,sex,residence and other related demographic factors.In addition to age-and sex-specific incidence rate analyses,we analyze the data to explore the incidence distribution by rural-urban differences among the 8 districts of the province.We also compared the incidence rates of Gharbiah to the rates of the Surveillance Epidemiology and End Results(SEER) data of the United States.RESULTS:Over the 9 year-period,1364 colorectal cancer cases were included.The disease incidence under age 40 years was relatively high(1.3/10 5) while the incidence in the age groups 40 and over was very low(12.0/10 5,19.4/10 5 and 21.2/10 5 in the age groups 40-59 years,60-69 years and > 70 years,respectively).The vast majority of tumors(97.2%) had no polyps and 37.2% of the patients presented with primary lesions in the rectum.Colorectal cancer was more common in patients from urban(55%) than rural(45%) areas.Regional differences in colon and rectal cancer incidence in the 8 districts of the study province may reflect different etiologic patterns in this population.The registry data of Egypt shows a slightly higher incidence of colorectal cancer than the United States in subjects under age 40 years.The results also shows significantly lower incidence of colorectal cancer in subjects over age 40 years compared to the same age group in the United States SEER.CONCLUSION:Low rate of polyps,low incidence in older subjects,and high rate of rectal cancer in Egypt.Future studies should explore clinical and molecular disease patterns. | Darlene Veruttipong Amr S Soliman Samuel F Gilbert Taylor S Blachley Ahmed Hablas Mohamed Ramadan Laura S Rozek Ibrahim A Seifeldin | 2012 | World Journal of Gastroenterology2012，18，30： | 12 |
| 2 | Magnitude of modulation of gene expression in aneuploid maize depends on the extent of genomic imbalance显示文摘Aneuploidy has profound effects on an organism,typically more so than polyploidy,and the basis of this contrast is not fully understood.A dosage series of the maize long arm of chromosome 1(1L)was used to compa re relative global gene expression in diffe rent types and degrees of aneuploidy to gain insights into how the magnitude of genomic imbalance as well as hypoploidy affects global gene expression.While previously available methods require a selective examination of specific genes,RNA sequencing provides a whole-genome view of gene expression in aneuploids.Most studies of global aneuploidy effects have concentrated on individual types of aneuploids because multiple dose aneuploidies of the same genomic region are difficult to produce in most model genetic organisms.The genetic toolkit of maize allows the examination of multiple ploidies and 1-4 doses of chromosome arms.Thus,a detailed examination of expression changes both on the varied chromosome arms and elsewhere in the genome is possible,in both hypoploids and hyperploids,compared with euploid controls.Previous studies observed the inverse trans effect,in which genes not varied in DNA dosage were expressed in a negative relationship to the varied chromosomal region.This response was also the major type of changes found globally in this study.Many genes varied in dosage showed proportional expression changes,though some were seen to be partly or fully dosage compensated.It was also found that the effects of aneuploidy were progressive,with more severe aneuploids producing effects of greater magnitude. | Adam F·Johnson Jie Hou Hua Yang Xiaowen Shi Chen Chen Md Soliman Islam Tieming Ji Jianlin Cheng James A·Birchler | 2020 | Journal of Genetics and Genomics2020，47，2： | 3 |
| 3 | Effect of single subconjunctival injection of bevacizumab on primary pterygium:clinical,histopathological and immunohistochemical study显示文摘AIM:To evaluate the effect(clinically,histopathologically and immunohistochemically) and safety of a single intrapterygium injection of bevacizumab.METHODS:Prospective interventional study comprised 40 eyes of 40 patients with primary fleshy pterygia who attended the Outpatient Clinic of Department of Ophthalmology,Assiut University Hospitals,Egypt from May 2015 to May 2016.Patients were randomly classified into 2 groups:the first group received a single intralesional injection of bevacizumab(Avastin;Genentech,San Francisco,CA,USA);the second group comprised patients who did not receive subconjunctival bevacizumab.Excision of pterygium and conjunctival auto graft was done in both groups.The excised pterygium tissues were subjected to histopathological and immunohistochemical evaluation.RESULTS:The study comprised 40 eyes of 40 patients(33 men,7 women) of age range from 31-58 y.The study group included 22 eyes.The control group included 18 eyes.A decrease in the vascularity of the pterygium was noted in all injected cases.The mean vessel count was higher in non-injected pterygia than that in injected pterygia and the difference was statistically significant(P=0.001).Also,the mean vessel count in both groups was significantly higher than normal conjunctive(P=0.005 and 0.001).A statistically significant difference in vascular endothelial growth factor(VEGF) expression between injected and non-injected cases was detected in the epithelial,stromal and endothelial cells(P=0.0001,0.016,0.014).No serious intraoperative complications occurred in both groups.CONCLUSION:The use of single intra lesional injection of Avastin in pterygium decreased vascularity and decreased VEGF expression in injected pterygium after one month.Our study proved the effect of single intra lesional injection of Avastin on pterygium.Further studies may enable limiting the need for surgery and improve quality of life for patients with pterygia. | Tarek A Mohamed Wael Soliman Ahmed M.Fathalla Abeer El Refaie | 2018 | International Journal of Ophthalmology(English edition)2018，11，5： | 2 |
| 4 | 遗传性肥胖与心房颤动的关系显示文摘观察性研究已经确定了体质量指数(body mass index,BMI)与心房颤动之间的关联。然而,从观察性研究中推断因果关系会受到混杂因素、逆因果关系和偏倚的影响。该研究的主要目的是应用BMI的遗传学预测因子评估BMI与心房颤动之间的因果关系。方法:纳入1987-2002年期间在美国、冰岛和荷兰实施的7个前瞻性人群队列研究中基线无心房颤动的欧洲血统个体51 646人, | 刘莉 叶鹏 Chatterjee NA Giulianini F Geelhoed B Lunetta KL Misialek JR Niemeijer MN Rienstra M Rose LM Smith AV Arking DE Ellinor PT Heeringa J Lin H Lubitz SA Soliman EZ Verweij N Alonso A Benjamin EJ Gudnason V Stricker BH van der Harst P Chasman DI Albert CM | 2017 | 中华高血压杂志2017，25，2： | 2 |
| 5 | On the Voltage Mirrors and the Current Mirrors显示文摘 | Awad I A Soliman A M | 2002 | Analog Integrated Circuits and Signal Processing2002，32，： | 1 |
| 6 | New CMOS realization of the CCII- 显示文摘 | I A Awad A M Soliman | 1999 | IEEE transaction on circuits and systems-Ⅱ: Analog and digital signal processing1999，46，4： | 1 |
| 7 | Variational Iteration Method for Solving Burger's and Coupled Burger's Equations 显示文摘 | Abdou M A Soliman A A | 2005 | J Comput Appl Math2005，181，2： | 1 |
| 8 | Self - management program improves anticoaglation control and quality of life : A prospective randomized study 显示文摘 | Mohamed A Soliman H Ellen Van E | 2009 | Eur J Cardiothorac Surg2009，35，2： | 1 |
| 9 | Biological control of Sclerotinia minor using achitino|ytic bacteriumand actinomycetes显示文摘 | E1-Tarabily K Soliman M H Nassar A H | 2000 | Plant Pathology2000，49，： | 1 |
| 10 | Drug resistance evaluation of some commonly usedanti-coccidial drugs in broiler chickens 显示文摘 | Harfoush M A Hegazy A M Soliman A H | 2010 | J EgyptSoc Parasitoi2010，40，2： | 1 |
| 11 | Multiscale Three- Dimensional Scaffolds for Soft Tissue Engineering via Multimodal Electrospinning 显示文摘 | Soliman S Pagliari S Rinaldi A | 2010 | Acta Biomaterialia2010，6，4： | 1 |
| 12 | Early manifestations of 'sick euthyroid'syndrome in patients with compensated chornic heart failure显示文摘 | Shanoudy H Soliman A Moe S | 2001 | J Card Fail2001，7，2： | 1 |
| 13 | Notes from the field: practical issues in upgrading STD services based on experience from primary healthcare facilities in two Rwandan towns显示文摘 | Soliman C Mujyambwani A | 1998 | Sex Transm Inf1998，74，1： | 1 |
| 14 | Serum cadmium levels in pancreatic cancer patients from the East Nile Delta Region of Egypt,Environ显示文摘 | Kriegel A M Soliman A S Zhang Q | 2006 | Health Perspeet2006，114，： | 1 |
| 15 | A novel sine-wave generator using a single operational amplifier显示文摘 | SOLIMAN A M AWAD S S | 1978 | Proceedings of the IEEE1978，66，2： | 1 |
| 16 | Neonatal Jaundice: The Role of Laparoscopy显示文摘 | Hay S A Soliman H E Abdelrahman A H | 2000 | J Pediatr Surg2000，35，12： | 1 |
| 17 | Development and evaluation of fixed dose bi therapy sublingual tablets for treatment stress hypertension and anxiety显示文摘 | EL-NABARAWI M A TAYEL S A SOLIMAN N A et at | 2013 | J Pharm Bioallied Sci2013，5，3： | 1 |
| 18 | Contrasting molecular pathology of colorectal carcinoma in Egypatian and Western patients显示文摘 | Soliman A S Bondy M L EI-Badawy S A | 2001 | Br J Cancer2001，85，7： | 1 |
| 19 | Long-term/mid-term electric load forecasting based on short-term correlation and annual growth显示文摘 | AL-HAMADI H M SOLIMAN S A | 2005 | Electric Power Systems Research2005，74，： | 1 |
| 20 | Evaluation of dietary methionine, folic acid and cyanocobalamin (B12) and their interactions in laying hen performance显示文摘 | El-Husseiny O M Soliman A Z Omara I I et ol | 2008 | International J Poult Sci2008，7，5： | 1 |
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