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| 1 | Self-expanding metal stents for the palliation of malignant gastric outlet obstruction in patients with peritoneal carcinomatosis显示文摘AIM To evaluate the efficacy of self-expanding metal stents(SEMS) for the palliation of malignant gastric outlet obstruction in patients with and without peritoneal carcinomatosis(PC).METHODS We performed a retrospective analysis of 62 patients who underwent SEMS placement for treatment of malignant gastroduodenal obstruction at our hospital over a six-year period. Stents were deployed through the scope under combined fluoroscopic and endoscopic guidance. Technical success was defined as successful stent placement and expansion. Clinical success was defined as an improvement in the obstructive symptoms and discharge from hospital without additional parenteral nutrition. According to carcinomatosis status, patients were assigned into groups with or without evidence of peritoneal disease.RESULTS In most cases, obstruction was caused by pancreatic(47%) or gastric cancer(23%). Technical success was achieved in 96.8%(60/62), clinical success in 79%(49/62) of all patients. Signs of carcinomatosis were identified in 27 patients(43.5%). The diagnosis was confirmed by pathology or previous operation in 7 patients(11.2%) and suspected by CT, MRI or ultrasound in 20 patients(32.2%). Presence of carcinomatosis was associated with a significantly lower clinical success rate compared to patients with no evidence of peritoneal disease(66.7% vs 88.6%, P = 0.036). There was no significant difference in overall survival between patients with or without PC(median 48 d vs 70 d, P = 0.21), but patients showed significantly longer survival after clinical success of SEMS placement compared to those experiencing clinical failure(median 14.5 d vs 75 d, P = 0.0003).CONCLUSION Given the limited therapeutic options and a clinical success rate of at least 66.7%, we believe that SEMS are a reasonable treatment option in patients with malignant gastric outlet obstruction with peritoneal carcinomatosis. | Christoph Rademacher Matthias Bechtler Steffen Schneider Bettina Hartmann Johannes Striegel Ralf Jakobs | 2016 | World Journal of Gastroenterology2016，22，43： | 2 |
| 2 | Response of the central metabolism of Corynebacterium glutamicum to different flux burdens显示文摘 | Marx A Striegel K de Graaf A | | 0，，02： | 1 |
| 3 | Synthesis and evaluation of a novel series of pyrrolizine derivatives as dual cyclooxygenase-1 and 5-lipoxygenase inhibitors显示文摘 | Striegel HG Neher K | 1997 | Arch Pharm(Weinheim)1997，330，910： | 1 |
| 4 | DSMCast: a scalable approach for diffserv multicasting显示文摘 | STRIEGEL A MANIMARAN G | 2004 | Computer Networks2004，44，6： | 1 |
| 5 | Multiple neutral alkali halide attachments onto oligosaccharides in electrospray ionization mass spectrometry显示文摘 | Striegel Andre Micheal Timpa Judy Dommert Piotrowiak Piotr | 1997 | Int J Mass Spectrom Ion Proc1997，162，： | 1 |
| 6 | Differentiated services: Packet Scheduling with delay and loss differentiation显示文摘 | A Striegel G Manimaran | 2002 | Computer Communications2002，25，1： | 1 |
| 7 | Psychosocial adjustment in young adulthood of women who experienced an eating disorder during adolescence显示文摘 | Striegel -Moore RH Seeley JR Lewinsohn PM | 2003 | Am Acad Child Ad-olesc Psychiatry2003，42，5： | 1 |
| 8 | A sealable approach to diffServ muhieast 显示文摘 | Striegel A Manimaran G | 2004 | Computer Networks2004，44，6： | 1 |
| 9 | A Survey of QoS Multieasting Issues显示文摘 | STRIEGEL A MANINARAN G | 2002 | IEEE Communication Magazine2002，40，6： | 1 |
| 10 | Two eases of Lupus vulgaris in childhood and review of the clinical challenges 显示文摘 | Striegel AK Nazzal R Fabri M | 2014 | Klin Padiatr2014，226，1： | 1 |
| 11 | Air pollution,coatings,and cultural resources 显示文摘 | Striegel M F Guin E B Hallett K | 2003 | Prog Org Coat2003，48，： | 1 |
| 12 | Treatment of Contaminated Groundwater Using Permeable Reactive Barriers 显示文摘 | Striegel A Sanders D A Veenstra J N | 2001 | Environmental Geosciences2001，8，4： | 1 |
| 13 | A case for tree evolution in QoS multicasting 显示文摘 | Chakrabarti A Striegel A Manimaran G | 2006 | Computer Communications2006，29，11： | 1 |
| 14 | DSMCast:a scalable approach for DiffServ multicasting显示文摘 | Striegel A Manimaran G | 2004 | Computer Networks2004，44，6： | 1 |
| 15 | Thalidomide therapy for recalcitrant systemic onset arthritis显示文摘 | Lehman TJ Striegel KH Onel KB | 2002 | J Pediatr2002，140，1： | 1 |
| 16 | Air pollution,coatinss,and cultural resources显示文摘 | Striegel M F Guin E B Hallett K | | 0，，： | 1 |
| 17 | Multiple detection in size-exclusion chromatography of macromolecules显示文摘 | Striegel A M | 2005 | Anal Chem2005，77，： | 1 |
| 18 | Packer scheduling with delay and loss differentiation显示文摘 | Striegel A'Manimaran G | 2002 | Computer Communications''2002，25，1： | 1 |
| 19 | Imidazole inhibitors of cytokine release: probing substituents in the 2 position显示文摘 | Laufer SA Striegel HG Wagner GK | 2002 | JMed Chem2002，45，21： | 1 |
| 20 | Measuring the size of polymers with negative radii using MALS/QELS : an exploration of the thermodynamic radius 显示文摘 | Michelle J Smith Imad A Haidara Andr6 M Striegel | 2007 | Analyst2007，132，： | 1 |
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