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| 1 | Evidence-b&sed incorpor&tion of serum sodium concentr&tion into MELD显示文摘 | Biggins SW Kim WE Terr&ult NA et &l | 2006 | G&stroenterolo gy2006，150，6： | 1 |
| 2 | Modified Asphalt Pavement Materials显示文摘 | Terre R L Walter J L | 1986 | The European Experience1986，，4： | 1 |
| 3 | Autotoxicity of Chinese fir on seed germination and seeding growth 显示文摘 | Huang Z Q Terr Y H Wang S L | 2002 | Allelopathy J2002，9，2： | 1 |
| 4 | Childhood traumas: An outline and overview显示文摘 | Terr L C | 1991 | American Journal of Psychiatry1991，148，： | 1 |
| 5 | On the physical dimensions of the Avrami constant显示文摘 | Maffezzoli A Kenny J M Terre L | 1995 | Thermochimica Acta1995，269，： | 1 |
| 6 | An autoradiographic study of deltaaminolevulinic acid uptake by mouse brain显示文摘 | TERR L WEINER L P | 1983 | Exp Neurol1983，79，： | 1 |
| 7 | Chowchilla revisited: The effects of psychic trauma four years after a school-bus kidnapping 显示文摘 | TERR L C | 1983 | American Journal of Psychiatry1983，140，12： | 1 |
| 8 | A developmental perspective on family risk factors in somatozation显示文摘 | Terre L Ghiselli W | 1997 | J Psychosom Res1997，42，2： | 1 |
| 9 | Biomarkers assessment in juvenile Cyprinus carpio to waterborne cadmium 显示文摘 | Terre F R Salibia A A Ferrarlc L | 2000 | Environmental Pollution2000，109，： | 1 |
| 10 | Do somatic complaints predict subsequent symptoms of depression? 显示文摘 | Terre L Poston WS Forevt J | 2003 | Psychother Psychosom2003，72，5： | 1 |
| 11 | New NiMo catalysts supported on Al-containing SBA-16 for 4,6-DMDBT hydrodesulfurization effect of the alumination method显示文摘 | KLIMOVA T LIZAMA L AMEZCUA J C ROQUERO P TERRES E NAVARRETE J DOMINGUEZ J M | 2004 | Catal Today2004，98，12： | 1 |
| 12 | Luted phase oestradiol administration in ovarian stimulation cycles with GnRH antagonist is comparable to the GnRH agonist (long) protocol显示文摘 | CUNHA FILHO J S TERRES L F HOLANDA F | 2007 | J Assist Reprod Genet2007，17，7： | 1 |
| 13 | Too scared to cry: Psychic trauma in childhood 显示文摘 | Terr L | 1992 | New York: Basic Books1992，，： | 1 |
| 14 | Intertwined leukocyte balances in tumours and peripheral blood as robust predictors of right and left colorectal cancer survival显示文摘BACKGROUND Colorectal cancer(CRC)accounts for 9.4%of overall cancer deaths,ranking second after lung cancer.Despite the large number of factors tested to predict their outcome,most patients with similar variables show big differences in survival.Moreover,right-sided CRC(RCRC)and left-sided CRC(LCRC)patients exhibit large differences in outcome after surgical intervention as assessed by preoperative blood leukocyte status.We hypothesised that stronger indexes than circulating(blood)leukocyte ratios to predict RCRC and LCRC patient outcomes will result from combining both circulating and infiltrated(tumour/peritumour fixed tissues)concentrations of leukocytes.AIM To seek variables involving leukocyte balances in peripheral blood and tumour tissues and to predict the outcome of CRC patients.METHODS Sixty-five patients diagnosed with colon adenocarcinoma by the Digestive Surgery Service of the La Paz University Hospital(Madrid,Spain)were enrolled in this study:43 with RCRC and 22 with LCRC.Patients were followed-up from January 2017 to March 2021 to record overall survival(OS)and recurrence-free survival(RFS)after surgical interventions.Leukocyte concentrations in peripheral blood were determined by routine laboratory protocols.Paraffin-fixed samples of tumour and peritumoural tissues were assessed for leukocyte concentrations by immunohistochemical detection of CD4,CD8,and CD14 marker expression.Ratios of leukocyte concentration in blood and tissues were calculated and evaluated for their predictor values for OS and RFS with Spearman correlations and Cox univariate and multivariate proportional hazards regression,followed by the calculation of the receiver-operating characteristic and area under the curve(AUC)and the determination of Youden’s optimal cutoff values for those variables that significantly correlated with either RCRC or LCRC patient outcomes.RCRC patients from the cohort were randomly assigned to modelling and validation sets,and clinician-friendly nomograms were developed to predict OS and RFS from the respective significant indexes.The accuracy of the model was evaluated using calibration and validation plots.RESULTS The relationship of leukocyte ratios in blood and peritumour resulted in six robust predictors of worse OS in RCRC:CD8+lymphocyte content in peritumour(CD8pt,AUC=0.585,cutoff<8.250,P=0.0077);total lymphocyte content in peritumour(CD4CD8pt,AUC=0.550,cutoff<10.160,P=0.0188);lymphocyte-to-monocyte ratio in peritumour(LMRpt,AUC=0.807,cutoff<3.185,P=0.0028);CD8+LMR in peritumour(CD8MRpt,AUC=0.757,cutoff<1.650,P=0.0007);the ratio of blood LMR to LMR in peritumour(LMRb/LMRpt,AUC=0.672,cutoff>0.985,P=0.0244);and the ratio of blood LMR to CD8+LMR in peritumour(LMRb/CD8MRpt,AUC=0.601,cutoff>1.485,P=0.0101).In addition,three robust predictors of worse RFS in RCRC were found:LMRpt(AUC=0.737,cutoff<3.185,P=0.0046);LMRb/LMRpt(AUC=0.678,cutoff>0.985,P=0.0155)and LMRb/CD8MRpt(AUC=0.615,cutoff>1.485,P=0.0141).Furthermore,the ratio of blood LMR to CD4+LMR in peritumour(LMRb/CD4MRpt,AUC=0.786,cutoff>10.570,P=0.0416)was found to robustly predict poorer OS in LCRC patients.The nomograms showed moderate accuracy in predicting OS and RFS in RCRC patients,with concordance index of 0.600 and 0.605,respectively.CONCLUSION Easily obtainable variables at preoperative consultation,defining the status of leukocyte balances between peripheral blood and peritumoural tissues,are robust predictors for OS and RFS of both RCRC and LCRC patients. | Ramón Cantero-Cid Karla Marina Montalbán-Hernández Jenny Guevara Alejandro Pascual-Iglesias Elisa Pulido JoséCarlos Casalvilla Cristóbal Marcano Cristina Barragán Serrano Jaime Valentín Gloria Cristina Bonel-Pérez JoséAvendaño-Ortiz Verónica Terrón Roberto Lozano-Rodríguez Alejandro Martín-Quirós Elvira Marín Eva Pena Laura Guerra-Pastrián Eduardo López-Collazo Luis Augusto Aguirre | 2022 | World Journal of Gastrointestinal Oncology2022，14，1： | 1 |
| 15 | Spectral Correlation of Multicarrier Modulated Signals and Its Application for Signal Detection显示文摘 | ZHANG H J RUYET D L TERRE M | | 0，，： | 1 |
| 16 | Dealing with largemouth bass virus:benefits of multi-sector collaboration显示文摘 | Terre D R Schramm H L Grizzle J M | 2008 | Proc Annu Conf Southeast Assoc Fish and Wildl Agencies2008，62，： | 1 |
| 17 | A developmental perspective on family risk factors in somatization显示文摘 | Terre L Ghiselli W | 1997 | J Psyehosom Res1997，42，2： | 1 |
| 18 | A developmental perspective on family risk factors in somatization显示文摘 | Terre L Ghiselli W | 1997 | J Psychosom Res1997，42，2： | 1 |
| 19 | Relationships between peer status and health behaviors显示文摘 | TERRE L DRABMAN RS MEYDRECH EF | 1992 | Adolescence1992，27，107： | 1 |
| 20 | Serum zinc and copper concentrations and Cu/Zn rations in patients with hepatopathies or diabetes显示文摘 | Terres M C Navarro A M Martin L F | 1998 | J Trace Elem Med Biol1998，12，1： | 1 |
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