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| 1 | A hypothesis for treating inflammation and oxidative stress with hydrogen sulfide during age-related macular degeneration显示文摘Age-related macular degeneration(AMD) is a leading cause of blindness and is becoming a global crisis since affected people will increase to 288 million by 2040.Genetics,age,diabetes,gender,obesity,hypertension,race,hyperopia,iris-color,smoking,sun-light and pyroptosis have varying roles in AMD,but oxidative stress-induced inflammation remains a significant driver of pathobiology.Eye is a unique organ as it contains a remarkable oxygengradient that generates reactive oxygen species(ROS) which upregulates inflammatory pathways.ROS becomes a source of functional and morphological impairments in retinal pigment epithelium(RPE),endothelial cells and retinal ganglion cells.Reports demonstrated that hydrogen sulfide(H_2S) acts as a signaling molecule and that it may treat ailments.Therefore,we propose a novel hypothesis that H_2S may restore homeostasis in the eyes thereby reducing damage caused by oxidative injury and inflammation.Since H_2S has been shown to be a powerful antioxidant because of its free-radicals' inhibition properties in addition to its beneficial effects in age-relatedconditions,therefore,patients may benefit from H_2S salubrious effects not only by minimizing their oxidant and inflammatory injuries to retina but also by lowering retinal glutamate excitotoxicity. | Akash K George Mahavir Singh Rubens Petit Homme Avisek Majumder Harpal S SANDhu Suresh C Tyagi | 2018 | International Journal of Ophthalmology(English edition)2018，11，5： | 3 |
| 2 | Phenotypic instability and rapid gene silencing in newly formed Arabidopsis alloteraploids显示文摘 | Comai L Tyagi A P Winter K Holmes-Davis R Reynolds S H Stevens Y Byers B | 2000 | Plant Cell2000，12，9： | 2 |
| 3 | Simultaneous sewage sludge digestion and metal leaching: effect of aeration 显示文摘 | Filali-Meknassi Y Tyagi R D Narasiah K S | 2000 | Process Biochemistry2000，36，： | 2 |
| 4 | Assessment of the efficiency of various gene promoters via biolistics in leaf and regenerating seed callus of millets,Eleusine coracana and Echinochloa crusgalli显示文摘 | GUPTA P RAGHUVANSHI S TYAGI A K | 2001 | Plant Biotechnol2001，18，： | 1 |
| 5 | Negative thermal expansion in Er2W3O12 and Yb2W3O12 by high temperature X-ray diffraction显示文摘 | Sumithra S Tyagi A K Umarji A M | 2005 | Mater Sci Eng B2005，116，： | 1 |
| 6 | The 41 - amino - acid C - terminal region of the hepatitis E virus ORF3 protein interacts with bikunin,a kunitz- type serine protease inhibitor显示文摘 | TYAGI S SURJIT M LAL S K | 2005 | J Virol2005，79，12： | 1 |
| 7 | Postauricular, transpetrous, presigmoid approach for extensive skull base tumors in the pet roclival region:the successes and the travails显示文摘 | Behari S Tyagi I Banerji D | 2010 | Acta Neuro chir (Wien)2010，152，10： | 1 |
| 8 | A study of hepatopulmonary syndrome among patients of cirrhosis of liver and portal hypertension 显示文摘 | Hira H S Kumar J Tyagi S K | 2003 | Indian J Chest Dis Allied Sci2003，45，3： | 1 |
| 9 | Fabrication and Characterization of MzSnC (M = Ti, Zr, Hf and Nb) 显示文摘 | Barsoum M W Yaroschuk G Tyagi S | 1997 | Scrip Ma- ter1997，37，10： | 1 |
| 10 | A20/AN1 zinc-finger domain-containing proteins in plants and animals represent common elements in stress response显示文摘 | Vij S Tyagi AK | | 0，，： | 1 |
| 11 | Effects of seasons and hormones on crossability barriers and in vitro hybrid development between Vigna radiata and Vigna unguieulata 显示文摘 | Tyagi D K Chawla H S | 1999 | Acta Agronomica Hungariea1999，47，： | 1 |
| 12 | Heme oxygenase - 1 - derived carbon monoxide protects hearts from transplant associated ischemia reperfusion injury 显示文摘 | Akamatsu Y Haga M Tyagi S | 2004 | FASEB J2004，18，6： | 1 |
| 13 | The ORF3 protein of hepatitis e virus interacts with liver-specific alphal-microglobulin and its precursor alpha1-microglobulin/bikunin precursor(ambp) and expedites their exprot from the hepatocyte显示文摘 | TYAGI S SURJIT M ROY AK | 2004 | J Biol Chem2004，279，29： | 1 |
| 14 | Solubility of Ce^4+ and Sr^2+ in the pyrochlore lattice of Gd2Zr2O7 for simulation of Pu and alkaline earth metal显示文摘 | PATWE S J TYAGI A K | 2006 | Ceram Intern2006，32，： | 1 |
| 15 | Applications of nanomaterials in environmental science and engineering: review 显示文摘 | Shah G B Yan S Tyagi R D | 2009 | Pract Periodical of Haz Toxic and Radioactive Waste Mgmt2009，13，2： | 1 |
| 16 | Role of thoracic epidural block in improving post-operative outcome for septic patients:a preliminary report显示文摘 | TYAGI A SEELAN S SETHI AK | 2011 | Eur J Anaesthesiol2011，28，4： | 1 |
| 17 | Collagen network of the myocardium function,structural remodeling and regulatory mechanisms显示文摘 | Weber K T Sun Y Tyagi S C | 1994 | J Mol Cell Cardiol1994，26，3： | 1 |
| 18 | SCS-CN-basedmodeling of sediment yield显示文摘 | Mishra S K Tyagi J V Singh V P | 2006 | Hydrol2006，324，14： | 1 |
| 19 | Ecological opti- mization of an irreversible Ericsson cryogenic refrig- erator cycle 显示文摘 | TYAGI S CHEN J LIN G | 2005 | Int J Energy Res2005，29，13： | 1 |
| 20 | The peroxisome proliferator-activated receptor: A family of nuclear receptors role in various diseases 显示文摘 | Tyagi S Gupta P Saini AS | 2011 | Adv Pharm Technol Res2011，2，4： | 1 |
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