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| 1 | The value of postoperative hepatic regional chemotherapy in prevention of recurrence after radical resection of primary liver cancer显示文摘INTRODUCTIONIn China,primary liver cancer (PLC) ranks secondin cancer mortality since the 1990s.In the field ofPLC treatment,surgical resection remains the best,which includes large PLC resection,small PLCresection,re-resection of subclinical recurrence,aswell as cytoreduction and sequential resection forunresectable PLC.However,recurrence | Wu ZQ Fan J Qiu SJ Zhou J Tang ZY | 2000 | World Journal of Gastroenterology2000，6，1： | 19 |
| 2 | Mutation analysis of the FOXL2 gene in Chinese patients with blepharophimosis-ptosis-epicanthus inversus syndrome显示文摘 | Tang SJ Wang XK Lin LX Sun Y Wang YL Yu HB | 2006 | 中国生物学文摘2006，20，4： | 15 |
| 3 | LMP2-DC Vaccine Elicits Specific EBV-LMP2 Response to Effectively Improve Immunotherapy in Patients with Nasopharyngeal Cancer显示文摘Objective To evaluate the safety and effectiveness of a vaccine based on latent membrane protein 2(LMP2)modified dendritic cells(DCs)that boosts specific responses of cytotoxic T lymphocytes(CTLs)to LMP2 before and after intradermal injection in patients with nasopharyngeal carcinoma(NPC).Methods DCs were derived from peripheral blood monocytes of patients with NPC.We prepared LMP2-DCs infected by recombinant adenovirus vector expressing LMP2(rAd-LMP2).NPC patients were immunized with 2×105 LMP2-DCs by intradermal injection at week 0 and after the second and fourth weeks.Specific responses to LMP2 were detected by enzyme-linked immunospot(ELISPOT)assay at week 0 and at the fifth and eighth weeks.Local clinicians performed the follow-up and tracking of patients.Results We demonstrated that DCs derived from monocytes displayed typical DC morphologies;the expression of LMP2 in the LMP2-DCs vaccine was confirmed by immunocytochemical assay.Twenty-nine patients with NPC were enrolled in this clinical trial.The LMP2-DCs vaccine was well tolerated in all of the patients.Boosted responses to LMP2 peptide sub-pools were observed in 18 of the 29 patients with NPC.The follow-up data of 29 immunized patients from April,2010 to April 2015 indicated a five-year survival rate of 94.4%in responders and 45.5%in non-responders.Conclusion In this pilot study,we demonstrated that the LMP2-DCs vaccine is safe and effective in patients with NPC.Specific CTLs responses to LMP2 play a certain role in controlling and preventing the recurrence and metastasis of NPC,which warrants further clinical testing. | ZENG Yi SI Yong Feng LAN Gui Ping WANG Zhan ZHOU Ling TANG Min Zhong SJ O`Brien LAN Jiao ZHOU Xiang Yang WANG Yong Li TANG Juan ZHOU Zhi Xiang DU Hai Jun LIN Hui | 2020 | Biomedical and Environmental Sciences2020，33，11： | 2 |
| 4 | Prostate tumor from an Asia population: examination of bax, bel-2, p53 and ras and identification of bax as a prognostic marker 显示文摘 | CHIA SJ TANG WY ELEATAN J | 2000 | Br J Cancer2000，83，6： | 1 |
| 5 | A role for cysteinyl leukotrienes in airway remodeling in a mouse asthma model显示文摘 | Henderson WR Jr Tang LO Chu SJ | 2002 | Am J Respir Crit Care Med2002，165，1： | 1 |
| 6 | A role for cysteinyl leukotrienes in airway remodeling in a mouse asthma model显示文摘 | Henderson WR Tang LO Chu SJ | | 0，，： | 1 |
| 7 | Acute pancreatitis during pregnan-cy显示文摘 | Tang SJ Rodriguez EF Singh S | | 0，，01： | 1 |
| 8 | A role for cysteinyl leukotrienes in airway remodeling in a mouse asthma model 显示文摘 | Henderson WR Jr Tang LO Chu SJ Tsao SM Chiang GK Jones F Jonas M Pae C Wang H Chi EY | 2002 | Am J Respir Crit Care Med2002，165，1： | 1 |
| 9 | Multiple Solutions for Nonhomogeneous Schroinger-Maxwell Equations and Klein-Gordon-Max?well Equations on gl显示文摘 | CHEN SJ TANG C L | 2010 | Nonlinear Differ Equ Appl2010，17，5： | 1 |
| 10 | Application of secondary structure prediction in antisense drug design targeting protein kinase C-alpha mRNA and QSAR analysis 显示文摘 | Song HF Tang ZM Yuan SJ | 2000 | Acta Pharmacol Sin2000，21，1： | 1 |
| 11 | Association of estrogen receptor beta gene polymorphisms with susceptibility to ado- lescent idiopathic scoliosis显示文摘 | Zhang HQ Lu SJ Tang MX | 2009 | Spine2009，34，8： | 1 |
| 12 | The clinical utility and limitations of serum carbohydrate antigen (CA19-9) as a di- agnostic tool for pancreatic cancer and cholangiocarcinoma 显示文摘 | Singh S Tang SJ Sreenarasimhaiah J | 2011 | Dig Dis Sci2011，56，8： | 1 |
| 13 | A role for cysteinyl leukotrienes in airway remodeling in a mouse asthma model显示文摘 | Henderson WR JR Tang LO Chu SJ | 2002 | Am J Respir Crit Care Med2002，165，： | 1 |
| 14 | Clinieal implications of minimal residual disease monitoring by quantitative polymerase chain reaction in acute myeloid leukemia patients bearing nueleophosmin (NPMt)mutations 显示文摘 | Chou WC Tang JL Wu SJ | 2007 | Leukemia2007，21，5： | 1 |
| 15 | A rapamycin-sensitive signaling pathway contributes to long-term synaptic plasticity in the hippocampus显示文摘 | Tang SJ Reis G Kang H | 2002 | Proc Natl Acad Sci USA2002，99，5： | 1 |
| 16 | Epinephrine increases the severity of postresuseitation myocardial dysfunction显示文摘 | Tang WC Weil MH Sun SJ | 1995 | Circula- tion1995，92，10： | 1 |
| 17 | Tumor-derived tumor necrosis factor-alpha promotes progression and epithelial-mesenchymal transi- tion in renal cell carcinoma cells 显示文摘 | Chuang MJ Sun KH Tang SJ | 2008 | Cancer Sci2008，99，5： | 1 |
| 18 | A role for cysteinyl leukotrienes in airway remodeling in a mouse asthma model显示文摘 | Henderson WR Jr Tang LO Chu SJ | 2002 | Am J Respir Crit Care Med2002，165，3： | 1 |
| 19 | Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model显示文摘 | Reich SJ Fosnot J Kuroki A Tang W Yang X Magutre AM | 2003 | Mol Vis2003，9，： | 1 |
| 20 | Production of bacterial cellu- lose and enzyme from waste fiber sludge 显示文摘 | Cavka A Guo X Tang SJ | 2013 | Biotechnology for Biofuels2013，6，： | 1 |
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