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| 1 | MicroRNA-145 Regulates OCT4, SOX2, and KLF4 and Represses Pluripotency in Human Embryonic Stem Cells显示文摘 | Na Xu Thales Papagiannakopoulos Guangjin Pan James A. Thomson Kenneth S. Kosik | 2009 | Cell2009，，4： | 2 |
| 2 | Acidic heteroxylans from medicinal plants and their anti-ulcer activity显示文摘 | Thales R. Cipriani Caroline G. Mellinger Lauro M. de Souza Cristiane H. Baggio Cristina S. Freitas Maria C.A. Marques Philip A.J. Gorin Guilherme L. Sassaki Marcello Iacomini | 2008 | Carbohydrate Polymers2008，，2： | 2 |
| 3 | Milliwatt terahertz harmonic generation from topological insulator metamaterials显示文摘Achieving effcient,high-power harmonic generation in the terahertz spectral domain has technological applications,for example,in sixth generation(6G)communication networks.Massless Dirac fermions possess extremely large terahertz nonlinear susceptibilities and harmonic conversion effciencies.However,the observed maximum generated harmonic power is limited,because of saturation effects at increasing incident powers,as shown recently for graphene.Here,we demonstrate room-temperature terahertz harmonic generation in a Bi_(2)Se_(3) topological insulator and topological-insulator-grating metamaterial structures with surface-selective terahertz field enhancement.We obtain a third-harmonic power approaching the miliwatt range for an incident power of 75 mW-an improvement by two orders of magnitude compared to a benchmarked graphene sample.We establish a framework in which this exceptional performance is the result of thermodynamic harmonic generation by the massless topological surface states,benefiting from ultrafast dissipation of electronic heat via surface-bulk Coulomb interactions.These results are an important step towards on-chip terahertz(opto)electronic applications. | Klaas-Jan Tielrooij Alessandro Principi David Saleta Reig Alexander Block Sebin Varghese Steffen Schreyeck Karl Brunner Grzegorz Karczewski Igor Ilyakov Oleksiy Ponomaryov Thales V.A.G.de Oliveira Min Chen Jan-Christoph Deinert Carmen Gomez Carbonell Sergio O.Valenzuela Laurens W.Molenkamp Tobias Kiessling Georgy V.Astakhov Sergey Kovalev | 2022 | Light(Science & Applications)2022，11，11： | 2 |
| 4 | Animal modeling in bone research—Should we follow the White Rabbit?显示文摘Animal models are live subjects applied to translational research.They provide insights into human diseases and enhance biomedical knowledge.Livestock development has favored the pace of human social development over millennia.Today's society is more aware of animal welfare than past generations.The general public has marked objections to animal research and many species are falling into disuse.The search for an ideal methodology to replace animal use is on,but animal modeling still holds great importance to human health.Bone research,in particular,has unmet requirements that in vitro technologies cannot fully address.Standardizing novel models remains necessary and rabbits are gaining in popularity as potential bone models.Our aim here is to provide a broad overview of animal modeling and its ethical implications,followed by a narrower focus on bone research and the role rabbits are playing in the current scenario. | Aline Schafrum Macedo Caroline Cezaretti Feitosa Fernando Yoiti Kitamura Kawamoto Paulo Vinicius Tertuliano Marinho Isis dos Santos Dal‐Bo Bianca Fiuza Monteiro Leonardo Prado Thales Bregadioli Gabriel Antonio Covino Diamante Cassio Ricardo Auada Ferrigno | 2019 | Animal Models and Experimental Medicine2019，2，3： | 2 |
| 5 | Characterization of mucins in human lacrimal sac and nasolacrimal duct显示文摘 | Paulsen FP Corfield AP Hinz M Hoffmann W Schaudig U Thale AB | 2003 | Invest Ophthalmol Vis Sci2003，44，5： | 1 |
| 6 | Morphological studies of the optic canal显示文摘 | Thale A Jungmann K Paulsen F | 2002 | Orbit2002，21，2： | 1 |
| 7 | New insights into the pathophysiology of primary acquired dacry ostenosis显示文摘 | Paulsen FP Thale AB Maune S | 2001 | Ophthalmology2001，108，： | 1 |
| 8 | Animal model for the absorption of lipophilic substances from tear fluid by the epithelium of the nasolacrimal ducts 显示文摘 | Paulsen FP Foge M Thale AB | 2002 | Invest Ophthalmol VisSei2002，43，10： | 1 |
| 9 | The collagen architecture of the sclera-SEM and immunohistochemical studies显示文摘 | Thale A Tilimann B | | 0，，： | 1 |
| 10 | MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells 显示文摘 | Thales Papagiannakopoulos Alice Shapiro Kenneth SK | 2008 | Caneker Res2008，68，19： | 1 |
| 11 | Performance analysis of a grid connected photovoltaic park on the island of Crete 显示文摘 | Emmanuel K Sofoklis K Thales M P | 2009 | Energy Conversion and Management2009，50，3： | 1 |
| 12 | Ultrastructural analysis of the lamina cribrosa after radial optic neurotomy显示文摘 | Hasselbach H Thale A Bunse A | 2009 | Ann Anat2009，191，3： | 1 |
| 13 | The cavernous body of the human efferent tear ducts: function in tear out- flow mechanism 显示文摘 | Paulsen FP Thale AB Hallmann UJ | 2000 | Invest Ophthalomo Vis Sci2000，41，5： | 1 |
| 14 | SEM study of the collagen architecture of human laminal cribrosa:Normal and pathological findings显示文摘 | Thale A Tillmann B Rochels R | 1996 | Ophthalmological1996，210，： | 1 |
| 15 | Depressed mood and poor quality of life in male patients with chronic renal failure undergoing hemedialysis 显示文摘 | Thales Joel Lucilia | 2010 | Revista Brasileira De Psiquiatria2010，9，4： | 1 |
| 16 | Morphological studies of the optic canal显示文摘 | Jungmaun K Paulsen F | 2002 | Orbit2002，21，2： | 1 |
| 17 | Can HIPEC be used against platinum-resistance and for inducing sensitivity to PARP inhibitors in ovarian cancer?显示文摘Hyperthermic intraperitoneal chemotherapy(HIPEC)has emerged as a main comprehensive treatment of epithelial ovarian cancer(EOC).Despite much criticism to this approach,HIPEC has shown cost-effective benefits in both progression-free survival and overall survival for high tumor burden with no important impairment on patient-reported quality of life.On the other hand,the landscape of EOC treatment is changing rapidly and poly(ADP-ribose)polymerase inhibitors(PARPi)currently play an important role in the management of EOC based on recent trials.At this point,an important question to be scrutinized is what to expect from up-front HIPEC in the era of amazing benefits by the PARPi.Herein,we discuss the promising role of combining PARPi and HIPEC in the management of advanced EOC. | Thales Paulo Batista Graziela Zibetti Dal Molin | 2020 | Cancer Drug Resistance2020，3，3： | 1 |
| 18 | Acute kidney injury in human leptospirosis: an immunohistochemical study with pathophysiological correlation显示文摘 | Eduardo Rocha Araujo Antonio Carlos Seguro Anne Spichler Antonio J. Magaldi Rildo A. Volpini Thales Brito | 2010 | Virchows Archiv2010，，4： | 1 |
| 19 | Umbilical Venous catheter-analysisof malpositioning over a 10-year period显示文摘 | Haase R Hein M Thale V | 2011 | Z Geburtshilfe Neonatol2011，215，1： | 1 |
| 20 | Functional anatomy of human lacrimal duct epithelium显示文摘 | Thale A Kohla G | 1998 | AnatEmbryol(Betl)1998，198，1： | 1 |
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