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| 1 | Vasova- gal syncope: a prospective, randomized, crossover evalu- ation of the effect of propranolol, nadolol and placebo on syncope recurrence and patients'well-being显示文摘 | Flevari P Livanis E G Theodorakis G N | 2002 | J Am Coil Cardiol2002，40，3： | 1 |
| 2 | The role of central venous pressure and type of vascular control in blood loss during major liver resections 显示文摘 | Smymiotis V Kostopanagiotou G Theodoraki K | 2004 | Am J Surg2004，187，3： | 1 |
| 3 | Antiinflammatory effects of cardiac resynchronization therapy in patients with chronic heart failure显示文摘 | Theodorakis G Elevori P Kronpis C | 2006 | PACE2006，29，3： | 1 |
| 4 | Critical requirement of BAX tbr manifestation of apoptosis induced by muhiple stimuli in human epithelial cancer cells显示文摘 | Theodorakis P Lomonosova E Chinnadurai G | 2002 | Cancel' Res2002，62，12： | 1 |
| 5 | The role of central venous pressure and type of vascular control in blood loss during major liver resections显示文摘 | Smyrniotis V Kostopanagiotou G Theodoraki K | 2004 | Am J Surg2004，187，： | 1 |
| 6 | The role of central venous pressure and type of vascular control in blood loss during major liver resections 显示文摘 | Smyrniotis V Kostopanagiotou G Theodoraki K | 2004 | Am J Surg2004，187，3： | 1 |
| 7 | Thalidomide ameliorates portal hypertension via nitric oxide synthase independent reduced systolic blood pressure显示文摘AIM: Portal hypertension is a common complication of liver cirrhosis and significantly increases mortality and morbidity.Previous reports have suggested that the compound thalidomide attenuates portal hypertension(PHT).However, the mechanism for this action is not fully elucidated.One hypothesis is that thalidomide destabilizes tumor necrosis factor α(TNFα) mR NA and therefore diminishes TNFα induction of nitric oxide synthase(NOS) and the production of nitric oxide(NO).To examine this hypothesis, we utilized the murine partial portal vein ligation(PVL) PHT model in combination with endothelial or inducible NOS isoform gene knockout mice.METHODS: Wild type, inducible nitric oxide synthase(i NOS)-/- and endothelial nitric oxide synthase(e NOS)-/-mice received either PVL or sham surgery and were given either thalidomide or vehicle.Serum nitrate(total nitrate, NOx) was measured daily for 7 d as a surrogate of NO synthesis.Serum TNFα level was quantified by enzyme-linked immunosorbent assay.TNFα m RNA was quantified in liver and aorta tissue by reverse transcription-polymerase chain reaction.PHT was determined by recording splenic pulp pressure(SPP) and abdominal aortic flow after 0-7 d.Response to thalidomide was determined by measurement of SPP and mean arterial pressure(MAP).RESULTS: SPP, abdominal aortic flow(Qao) and plasma NOx were increased in wild type and i NOS-/-PVL mice when compared to sham operated control mice.In contrast, SPP, Qao and plasma NOx were not increased in e NOS-/- PVL mice when compared to sham controls.Serum TNFα level in both sham and PVL mice was below the detection limit of the commercial ELISA used.Therefore, the effect of thalidomide on serum TNFα levels was undetermined in wild type, e NOS-/-or i NOS-/- mice.Thalidomide acutely increased plasma NOx in wild type and e NOS-/- mice but not i NOS-/-mice.Moreover, thalidomide temporarily(0-90 min) decreased mean arterial pressure, SPP and Qao in wild type, e NOS-/- and i NOS-/- PVL mice, after which time levels returned to the respective baseline.CONCLUSION: Thalidomide does not reduce portalpressure in the murine PVL model by modulation of NO biosynthesis.Rather, thalidomide reduces PHT by decreasing MAP by an undetermined mechanism. | Nicholas G Theodorakis Yining N Wang Vyacheslav A Korshunov Mary A Maluccio Nicholas J Skill | 2015 | World Journal of Gastroenterology2015，21，14： | 1 |
| 8 | The role of central venous pressure and type of vascular control in blood loss during major liver resections显示文摘 | Smyrniotis V Kostopanagiotou G Theodoraki K | 2004 | Am J Surg2004，187，3： | 1 |
| 9 | Methodology of head-up tilt testing in patients with unexplained syncope显示文摘 | Fitzpatrick AP Theodorakis G Vardas P | 1991 | J Am Coll Cardiol1991，17，： | 1 |
| 10 | Dual chamber pacing aborts vasovagal syncope induced by head-up 60° tilt 显示文摘 | Fitzpatrick AP Theodorakis G Ahmed R | 1991 | PACE1991，4，： | 1 |
| 11 | The role of central venous pressure and type of vascular control in blood loss during major liver resections显示文摘 | Smyrniotis V Kostopanagiotou G Theodoraki K | 2004 | Am J Surg2004，187，3： | 1 |
| 12 | The role of nitric oxide synthase isoforms in extrahepatic portal hypertension: studies in gene-knockout mice显示文摘 | Nicholas G Theodorakis Yi-ning Wang Nicholas J Skill Matthew A Metz Paul A Cahill Eileen M Redmond James V Sitzmann | 2003 | Gastroenterology2003，，5： | 1 |
| 13 | Heat shock -induced translational control of HSP70 and globin synthesis in chicken reticulocytes 显示文摘 | BANERJI S S THEODORAKIS N G MORIMOTO R I | 1984 | Mol Cell Biol1984，4，11： | 1 |
| 14 | Thermotolerant cells show an attenuated expression of HSP70 after heat shock 显示文摘 | THEODORAKIS N G DRUJAN D MAIO A D | 1999 | J Biol Chem1999，274，12： | 1 |
| 15 | Methodology of head-up tilt testing in patients with unexplained syncope 显示文摘 | Fitzpatrick AP Theodorakis G Vardas P | 1991 | J Am Coll Cardiol1991，17，： | 1 |
| 16 | Dual chamber pacing aborts vasovagal syncope induced by head up 60 degree tilt显示文摘 | FITZPATRICK A P THEODORAKIS G AHMED R | 1991 | PACE1991，14，1： | 1 |
| 17 | Critial requirement of BAX for manifestation of apoptosis induced by multiple stimuli in human epithelial cancer cell显示文摘 | Theodorakis P Lomomosova E Chinnadurai G | 2000 | Cancer Res2000，62，12： | 1 |
| 18 | Thermotolerant cells show an attenuated expression of HSP70 after heat shock显示文摘 | Theodorakis N G Drujan D De Maio A | 1999 | J Biol Chem1999，274，12： | 1 |
| 19 | Initial evaluation of a smoking cessation program incorporating physical activity promotion to Greek adults in antismoking clinics显示文摘 | Hassandra M Kofou G Zourbanos N Gratsani S Zisi V Theodorakis Y | | 0，，： | 1 |
| 20 | Monitoring capabil-ities of cardiac rhythm management devices显示文摘 | Andrikopoulos G Tzeis S Theodorakis G | 2010 | Europace2010，12，1： | 1 |
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