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| 1 | Gastroenterologist perceptions of faecal microbiota transplantation显示文摘AIM: To explore gastroenterologist perceptions towards and experience with faecal microbiota transplantation(FMT).METHODS: A questionnaire survey consisting of 17 questions was created to assess gastroenterologists' attitude towards and experience with FMT. This was anonymously distributed in hard copy format amongst attendees at gastroenterology meetings in Australia between October 2013 and April 2014. Basic descriptive statistical analyses were performed.RESULTS: Fifty-two clinicians participated. Twenty one percent had previously referred patients for FMT,8% more than once. Ninety percent would refer patients with Clostridium difficile infection(CDI) for FMT if easily available,37% for ulcerative colitis,13% for Crohn's disease and 6% for irritable bowel syndrome. Six percent would not refer any indication,including recurrent CDI. Eighty-six percent would enroll patients in FMT clinical trials. Thirty-seven percent considered the optimal mode of FMT administration transcolonoscopic,17% nasoduodenal,13% enema and 8% oral capsule. The greatest concerns regarding FMT were: 42% lack of evidence,12% infection risk,10% non infectious adverse effects/lack of safety data,10% aesthetic,10% lack of efficacy,4% disease exacerbation,and 2% inappropriate use; 6% had no concerns. Seventy seven percent believed there is a lack of accessibility while 52% had an interest in learning how to provide FMT. Only 6% offered FMT at their institution.CONCLUSION: Despite general enthusiasm,most gastroenterologists have limited experience with,or access to,FMT. The greatest concerns were lack of supportive evidence and safety issues. However a significant proportion would refer indications other than CDI for FMT despite insufficient evidence. These data provide guidance on where education and training are required. | Sudarshan Paramsothy Alissa J Walsh Thomas Borody Douglas Samuel Johan van den Bogaerde Rupert WL Leong Susan Connor Watson Ng Hazel M Mitchell Nadeem O Kaakoush Michael A Kamm | 2015 | World Journal of Gastroenterology2015，21，38： | 5 |
| 2 | 中国启东肝癌预防:黄曲霉毒素生物标志物研究的经验(英文)显示文摘原发性肝癌一直是中国启东癌症死亡的首要原因,这一地区的110万居民中大约每年有800人死于原发性肝癌。流行病学研究已经强调了乙肝病毒感染和肝致癌物黄曲霉素的饮食暴露在启东和其他流行地区作为关键相互作用的风险决定因素的重要性。由于生物标志物的发展,使得在病例对照研究和其他群体研究中可以检测这些风险因素的流行程度。20世纪80年代曾经在启东进行了乙肝病毒疫苗接种试点,但直到本世纪初才在新生儿上普遍接种。尽管目前疫苗接种对癌症死亡率的影响微乎其微,但该项目旨在减缓这一地区未来几代人肝脏疾病包括肝癌的发展。减少对黄曲霉毒素暴露的策略也是必需的,尤其是对于那些已经感染乙肝病毒的人群。我们已经进行了一系列原理验证性的临床试验,包括使用药物、膳食补充剂和食物来改变不可避免的暴露后黄曲霉素的代谢及排出。使用黄曲霉素生物标志物作为中间指标,奥替普拉、叶绿素和西兰花豆芽饮料已被证明有效,突出了低成本化学预防途径在预防环境致癌中的作用。值得注意的是,最近对存档的血清样本的回顾性分析表明,启东的黄曲霉素暴露在过去的25年里下降了40倍,这可能是由从玉米到大米的主食变化带来的。因此,一级预防,伴随着20世纪80年代经济和农业政策改变的作用,带来了出乎意料的在短时间内消除这个地区肝癌地方性流行的希望。 | Patricia A.Egner 王金兵 朱源荣 Lisa P.Jacobson Derek Ng Alvaro Munoz Jed W.Fahey 陈建国 陈陶阳 钱耕荪 John D.Groopman Thomas W.Kensler | 2013 | 化学进展2013，25，9： | 5 |
| 3 | A Subpopulation of CD26 + Cancer Stem Cells with Metastatic Capacity in Human Colorectal Cancer显示文摘 | Roberta Pang Wai Lun Law Andrew C.Y. Chu Jensen T. Poon Colin S.C. Lam Ariel K.M. Chow Lui Ng Leonard W.H. Cheung Xiao R. Lan Hui Y. Lan Victoria P.Y. Tan Thomas C. Yau Ronnie T. Poon Benjamin C.Y. Wong | 2010 | Cell Stem Cell2010，，6： | 4 |
| 4 | High-performance oxygen reduction and evolution carbon catalysis: From mechanistic studies to device integration显示文摘能容易集成于存在的高效、便宜的氧减小和进化催化剂的发展设备为利用 O 2-H2 O 化学,例如再生燃料房间和金属空气电池。此处,我们报导 NH 3-activated 做 N 的层次碳(NHC ) 催化剂经由一条可伸缩的线路综合了,并且表明它的设备集成。NHC 催化剂为氧减小反应(ORR ) 和氧进化反应(OER ) 展出了好性能,当综合时,借助于电气化学的研究和评估示威了进一个再生燃料房间的氧电极。为 ORR 和 OER 观察的活动比得上最先进的磅和红外催化剂在碱的环境完成的那些。我们进一步通过密度为电气化学的活动作为活跃地点识别了碳缺点的关键角色功能的理论计算和高分辨率的 TEM 可视化。这个工作加亮 NHC 的潜力在再生燃料房间并且可能代替商业宝贵金属为断断续续的可更新的精力的划算的存储的金属空气电池。 | John W. F. To Jia Wei Desmond Ng Samira Siahrostami Ai Leen Koh Yangjin Lee Zhihua Chen Kara D. Fong Shucheng Chen Jiajun He Won-Gyu Bae Jennifer Wilcox Hu Young Jeong Kwanpyo Kim Felix Studt Jens K. Nфrskov Thomas F. Jaramillo Zhenan Bao | 2017 | Nano Research2017，10，4： | 4 |
| 5 | Critical analysis of feeding jejunostomy following resection of upper gastrointestinal malignancies显示文摘AIM To assess nutritional recovery,particularly regarding feeding jejunostomy tube(FJT)utilization,following upper gastrointestinal resection for malignancy. METHODS A retrospective review was performed of a prospectively-maintained database of adult patients who underwent esophagectomy or gastrectomy(subtotal or total)for cancer with curative intent,from January 2001 to June 2014. Patient demographics,the approach to esophagectomy,the extent of gastrectomy,FJT placement and utilization at discharge,administration of parenteral nutrition(PN),and complications were evaluated. All patients were followed for at least ninety days or until death.RESULTS The 287 patients underwent upper GI resection,comprised of 182 esophagectomy(n=107 transhiatal,58.7%; n=56 Ivor-Lewis,30.7%)and 105 gastrectomy [n=63 subtotal(SG),60.0%; n=42 total(TG),40.0%]. 181 of 182 esophagectomy patients underwent FJT,compared with 47 of 105 gastrectomy patients(99.5% vs 44.8%,P < 0.0001),of whom most had undergone TG(n=39,92.9% vs n=8 SG,12.9%,P < 0.0001). Median length of stay was similar between esophagectomy and gastrectomy groups(14.7 d vs 17.1 d,P=0.076). Upon discharge,87 esophagectomy patients(48.1%)were taking enteral feeds,with 53(29.3%)fully and 34(18.8%)partially dependent. Meanwhile,20 of 39 TG patients(51.3%)were either fully(n=3,7.7%)or partially(n=17,43.6%)dependent on tube feeds,compared with 5 of 8 SG patients(10.6%),all of whom were partially dependent. Gastrectomy patients were significantly less likely to be fully dependent on tube feeds at discharge compared to esophagectomy patients(6.4% vs 29.3%,P=0.0006). PN was administered despite FJT placement more often following gastrectomy than esophagectomy(n=11,23.4% vs n=7,3.9%,P=0.0001). FJT-specific complications requiring reoperation within 30 d of resection occurred more commonly in the gastrectomy group(n=6),all after TG,compared to 1 esophagectomy patient(12.8% vs 0.6%,P=0.0003). Six of 7 patients(85.7%)who experienced tube-related complications required PN.CONCLUSION Nutritional recovery following esophagectomy and gastrectomy is distinct. Operations are associated with unique complication profiles. Nutritional supplementation alternative to jejunostomy should be considered in particular scenarios. | Andrew M Blakely Saad Ajmal Rachel E Sargent Thomas T Ng Thomas J Miner | 2017 | World Journal of Gastrointestinal Surgery2017，9，2： | 4 |
| 6 | the Toyota Production System Applying the lean principles of to reduce wait times in the e-mergency department显示文摘 | Ng D Vail G Thomas S | 2010 | CJEM2010，12，1： | 1 |
| 7 | Association between serum alkaline phosphatase and C-reative protein in the United States National Health and Nutrition Examination Survey 2005 - 2006显示文摘 | Webber M Krishnan A Thomas NG | 2010 | Clin Chem Lab Med2010，48，2： | 1 |
| 8 | A Modified Neural Network for Improving River Flow Prediction显示文摘 | Hu Tiesong Lam K C Thomas Ng S | 2005 | Hydrological Sciences Journal2005，50，2： | 1 |
| 9 | Fabrication and anti-microbial evaluation of drug loaded polyiactide space filler intendedfor ridge preservation following tooth extraction显示文摘 | Thomas NG Sanil GP Rajmohan G | 2011 | J Indian SocPeriodontol2011，15，3： | 1 |
| 10 | Fabrica- tion and anti-microbial evaluation of drug loaded polylactide space filler intended for ridge preserva- tion following tooth extraction显示文摘 | Thomas NG Sanil GP Rajmohan G | 2011 | J Indian Soc Pe- riodontol2011，15，3： | 1 |
| 11 | Tissue Doppler echocardiography 显示文摘 | Ng AC Thomas L Leung DY | 2010 | Minerva Cardioangiol2010，58，3： | 1 |
| 12 | Biogeography of the Indo-Australian Archipelago显示文摘 | David J. Lohman Mark de Bruyn Timothy Page Kristina von Rintelen Robert Hall Peter K.L. Ng Hsi-Te Shih Gary R. Carvalho Thomas von Rintelen | 2011 | Annual Review of Ecology, Evolution, and Systematics2011，，： | 1 |
| 13 | Immunoluminometric assay for the midregion of pro-atrial natriuretic peptide in human plasma显示文摘 | Morgenthaler NG Struck J Thomas B | 2004 | Clin Chem2004，50，1： | 1 |
| 14 | DEXamethasone modulates insulin receptor expression and subceUular distribution of the glucose transporter GLUT 1 in U106-01,a clonal osteogenic sarcoma cell line 显示文摘 | Thomas DM Rogers SD Ng KW | 1996 | J Mol Endocrinol1996，17，1： | 1 |
| 15 | Risk Factors for Pneumothorax and Bleeding after CT-guided Percutaneous Coaxial Cutting Needle Biopsy of Lung Lesions显示文摘 | Kee-Min Yeow Lai-Chu See Kar-Wai Lui Meng-Chih Lin Thomas Chang-Yao Tsao Kwai-Fong Ng Hui-Ping Liu | 2001 | Journal of Vascular and Interventional Radiology2001，，11： | 1 |
| 16 | Association be- tween serum alkaline phosphatase and C-reactive protein in the United States National Health and Nutrition Examination Survey 2005-2006显示文摘 | Webber M Krishnan A Thomas NG | 2010 | Clin Chem Lab Med2010，48，2： | 1 |
| 17 | Curing Congenital Construction Industry Disorders through Relationally Integrated Supply Chains显示文摘 | Palaneeswaran E Kumaraaswamy M Rahman M Thomas Ng | 2003 | Building and Enviroment2003，，38： | 1 |
| 18 | A Knowledge-Based Approach to Effective Document Retrieval 显示文摘 | Fang Sheng Xien Fan Gary Thomas Peter NG | 2001 | Journal of System Integration2001，，10： | 1 |
| 19 | Client satisfaction and quality management systems in contractor organizations 显示文摘 | Ekambaram Palaneeswaran Thomas Ng Mohan Kumaraswamy | 2006 | Building and Environment2006，，41： | 1 |
| 20 | Applying a Genetic Algorithm-Based MultiobjectiveApproach for Time-Cost Optimization显示文摘 | ZHENG Daisy X M THOMAS S Ng KUMARAswAMY Mohan M | 2004 | Journal of Construction Engineering and Management2004，4，： | 1 |
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