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| 1 | Red blood cell distribution width in elderly hospitalized patients with cardiovascular disease显示文摘BACKGROUND Red blood cell distribution width(RDW)is elevated in patients with cardiovascular disease(CVD).AIM To determine RDW values and impact of CV and non-CV coexisting morbidities in elderly patients hospitalized with chronic CVD.METHODS This prospective study included 204 consecutive elderly patients(age 77.5[7.41]years,female 94[46%],left ventricular ejection fraction 53.00%[37.50,55.00])hospitalized with chronic CVD at the Cardiology Department of Larissa University General Hospital(Larissa,Greece)from January 2019 to April 2019.Elderly patients were selected due to the high prevalence of coexisting morbidities in this patient population.Hospitalized patients with acute CVD(acute coronary syndromes,new-onset heart failure[HF],and acute pericarditis/myocarditis),primary isolated valvular heart disease,sepsis,and those with a history of blood transfusions or cancer were excluded.The evaluation of the patients within 24 h from admission included clinical examination,laboratory blood tests,and echocardiography.RESULTS The most common cardiac morbidities were hypertension and coronary artery disease,with acutely decompensated chronic heart failure(ADCHF)and atrial fibrillation(AF)also frequently being present.The most common non-cardiac morbidities were anemia and chronic kidney disease followed by diabetes mellitus,chronic obstructive pulmonary disease,and sleep apnea.RDW was significantly elevated 15.48(2.15);121(59.3%)of patients had RDW>14.5%which represents the upper limit of normal in our institution.Factors associated with RDW in stepwise regression analysis were ADCHF(coefficient:1.406;95%confidence interval[CI]:0.830-1.981;P<0.001),AF(1.192;0.673 to 1.711;P<0.001),and anemia(0.806;0.256 to 1.355;P=0.004).ADCHF was the most significant factor associated with RDW.RDW was on average 1.41 higher for patients with than without ADCHF,1.19 higher for patients with than without AF,and 0.81 higher for patients with than without anemia.When patients were grouped based on the presence or absence of anemia,ADCHF and AF,heart rate was not increased in those with anemia but was significantly increased in those with ADCHF or AF.CONCLUSION RDW was elevated in elderly hospitalized patients with chronic CVD.Factors associated with RDW were anemia and CV factors associated with elevated heart rate(ADCHF,AF),suggesting sympathetic overactivity. | Andrew Xanthopoulos Konstantinos Tryposkiadis Apostolos Dimos Angeliki Bourazana Alexandros Zagouras Nikolaos Iakovis Michail Papamichalis Grigorios Giamouzis George Vassilopoulos John Skoularigis Filippos Triposkiadis | 2021 | World Journal of Cardiology2021，13，9： | 13 |
| 2 | Left atrial volume and function in valvular aortic stenosis显示文摘 | Triposkiadis F Pitsavos C Boudoulas H | 1993 | J Heart Valve Dis1993，2，1： | 1 |
| 3 | Effect of atrial fibrillation on exercise capacity in mitral stenosis显示文摘 | Triposkiadis F Trikas A Tentolouris K | 1995 | Am J Cardiol1995，76，28： | 1 |
| 4 | Patent hemostasis of radial artery:Comparison of two methods显示文摘BACKGROUND Radial artery obstruction is the most common complication of coronary angiography performed via transradial access.Patent hemostasis can significantly reduce the risk of radial artery occlusion.Previous studies utilized sophisticated methods to evaluate radial artery patency.Simplified and easily applicable methods for successful patent hemostasis are currently lacking.AIM To determine which method(pulse oximeter vs the traditional radial artery palpation)is better to achieve patent hemostasis.METHODS This prospective,single center study included 299 consecutive patients who underwent coronary angiography or percutaneous coronary intervention between November 2017 and July 2019.Patients less than 18 years old,with a history of radial artery disease,or no palpable artery pulse were excluded from the study.Patients were randomly assigned to two groups.In the first group,radial artery flow was assessed by palpation of the artery during hemostasis(traditional method).In the second group,radial artery patency was estimated with the use of a pulse oximeter.Two different compression devices were used for hemostasis(air chamber and pressure valve).The primary study endpoint was the achievement of successful patent hemostasis.RESULTS The two groups(pulse oximeter vs artery palpation)had no significant differences in age,sex,body mass index,risk factors,or comorbidities except for supraventricular arrhythmias.The percentage of patients with successful patent hemostasis was significantly higher in the pulse oximeter group(82.2%vs 68.1%,P=0.005).A lower percentage of patients with spasm was recorded in the pulse oximeter group(9.9%vs 19.0%,P=0.024).The incidence of local complications,edema,bleeding,hematoma,vagotonia,or pain did not differ between the two groups.In the multivariate analysis,the use of a pulse oximeter(OR:2.35,95%CI:1.34-4.13,P=0.003)and advanced age(OR:1.04,95%CI:1.01-1.07,P=0.006),were independently associated with an increased probability of successful patent hemostasis.The type of hemostatic device did not affect patent hemostasis(P=0.450).CONCLUSION Patent hemostasis with the use of pulse oximeter is a simple,efficient,and safe method that is worthy of further investigation.Larger randomized studies are required to consider its clinical implications. | Vassileios Kyriakopoulos Andrew Xanthopoulos Michail Papamichalis Spyridon Skoularigkis Chara Tzavara Emmanouil Papadakis Sotirios Patsilinakos Filippos Triposkiadis John Skoularigis | 2021 | World Journal of Cardiology2021，13，10： | 1 |
| 5 | Successful management of Brucella melitensis endocarditis with combined medical and surgical approach显示文摘 | Hadjinikolaou L Triposkiadis F Zairis M | 2001 | Eur J Cardiothorac Surg2001，19，： | 1 |
| 6 | Anfihypertensive effect of manidipine 显示文摘 | Roca-Cusachs A Triposkiadis F | 2005 | Drugs2005，65，2： | 1 |
| 7 | The sympa thetic nervous system in heart failure physiology, pathophysiol ogy,and clinical implications显示文摘 | Triposkiadis F Karayannis G Giamouzis G | 2009 | J Am Coil Cardiol2009，54，： | 1 |
| 8 | Carotid plaque composition in stable and unstable coronary artery disease显示文摘 | Triposkiadis F Sitafidis G Kostoulas J | 2005 | Am Heart J2005，150，4： | 1 |
| 9 | Left atrial remodeling in patients yotnger than 70 years with diastolic and systolic heart failure显示文摘 | Triposkiadis F Harbas C Kelepeshis G | | 0，，10： | 1 |
| 10 | The sympathetic nervous system in heart failure physiology, pathophysiology, and clinical implications 显示文摘 | Triposkiadis F Karayannis G Giamouzis G | 2009 | J Am Coll Cardiol2009，54，19： | 1 |
| 11 | The sympathetic nervous system in heart failure:physiology,pathophysiology,and clinical implications显示文摘 | Triposkiadis F Karayannis G Giamouzis G | 2009 | J Am Coll Cardiol2009，54，19： | 1 |
| 12 | The sympathetic nervous system in heart failure显示文摘 | Triposkiadis F Karayannis G Giamouzis G | 2009 | J Am Coll Cardiol2009，54，19： | 1 |
| 13 | Echocardiographic assessment of left atrial ejection force and kinetic energy in chronic heart failure显示文摘 | Triposkiadis F Harbas C Sitafidis G | 2008 | Int J Cardiovasc Imaging2008，24，： | 1 |
| 14 | Carotid plaque composition in stable and unstable coronary artery disease显示文摘 | Triposkiadis F Sitafidis G Kostoulas J | 2005 | American Heart Journal2005，150，4： | 1 |
| 15 | Carotid plaque composition in stable and unstable coronary artery disease显示文摘 | Triposkiadis F Sitafidis G Kostoulas J Skoularigis J Zintzaras E Fezoulidis I | 2005 | Am Heart J2005，150，4： | 1 |
| 16 | Lack of a thrombotic tendency in patients with acute myocardial infarction and angiographically normal coronary arteries 显示文摘 | Kyriakidis M Androulakis A Triposkiadis F | 1995 | Cardiology1995，86，1： | 1 |
| 17 | Carotid plaque compo- sition in stable and unstable coronary artery disease显示文摘 | Triposkiadis F Sitafidis G Kostoulas J | 2005 | Am Heart J2005，150，4： | 1 |
| 18 | Carotid plaquecomposition in stable and unstable coronary artery- diesaes显示文摘 | Triposkiadis F Sitafidis G Kostoulas J | 2005 | American Heart J2005，150，4： | 1 |
| 19 | Acute hemodynamic effects of moderate doses of nebivolol versus metoprolol in patients with systolic heart failure显示文摘 | Triposkiadis F Giamouzis G Kelepeshis G | 2007 | Int J Clin Pharmacol Ther2007，45，2： | 1 |
| 20 | Left atrial volume and function in patients with mitral stenosis in sinus rhythm显示文摘 | Boudoulas H Triposkiadis F Barrington W | 1991 | Actra Cardiologica1991，46，： | 1 |
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