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142篇 您的检索式:作者名="Tsakris"
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1Post-partum reactivation of chronic hepatitis B virus infection among hepatitis B e-antigen-negative women显示文摘AIM: To investigate the frequency and timing of post-partum chronic hepatitis B virus(HBV) reactivation and identify its pre-partum predictors. METHODS: Forty-one hepatitis B e antigen(HBe Ag)-negative chronic HBV infected pregnant women were prospectively evaluated between the 28 th and the 32 nd week of gestation. Subjects were re-evaluated at 3-mo intervals during the first post-partum year and every 6 mo during the following years. HBV DNA was determined using real-time reverse transcription polymerase chain reaction(Cobas Taq Man HBV Test) with a lower detection limit of 8 IU/m L. Post-partum reactivation(PPR) was defined as abnormal alanine aminotransaminase(ALT) levels and HBV DNA above 2000 IU/m L. RESULTS: Fourteen out of 41 women(34.1%) had prepartum HBV DNA levels > 2000 IU/m L, 18(43.9%) had levels < 2000 IU/m L and 9(21.9%) had undetectable levels. Fourteen women were lost to follow-up(failure to return). PPR occurred in 8 of the 27(29.6%) women evaluated, all within the first 6 mo after delivery(5 at month 3; 3 at month 6). Five of the 6(83.3%) women with pre-partum HBV DNA > 10000 IU/m L exhibited PPR compared with 3 of the 21(14.3%) women with HBV DNA < 10000 IU/m L(two with HBV DNA > 2000 and the third with HBV DNA of 1850IU/m L), P = 0.004. An HBV DNA level ≥ 10000 IU/m L independently predicted post-partum HBV infection reactivation(OR = 57.02, P = 0.033). Mean pre-partum ALT levels presented a non-significant increase in PPR cases(47.3 IU/L vs 22.2 IU/L, respectively, P = 0.094).CONCLUSION: In the present study, PPR occurred in approximately 30% of HBe Ag-negative pregnant women; all events were observed during the first semester after delivery. Pre-partum HBV DNA level > 10000 IU/m L predicted PPR.Ioannis Elefsiniotis Elena Vezali Dimitrios Vrachatis Sofia Hatzianastasiou Stefanos Pappas George Farmakidis Georgia Vrioni Athanasios Tsakris 2015World Journal of Gastroenterology2015,21,4:7
2Single nucleotide polymorphisms of Toll-like receptors and susceptibility to infectious diseases 显示文摘Skevaki C Pararas M Kostelidou K Tsakris A Routsias JG 2015Clin Exp Immunol2015,180,2:1
3Inhibitor-based methods for the detection of KPC carbapenemase-producing Enterobacteriaceae in clinical practice by using boronic acid compounds显示文摘Pournaras S Poulou A Tsakris A 0,,07:1
4Diversity of β-lactamases among Klebsiella pneumoniae strains isolated in a university hospital in Greece显示文摘 TZOUVELEKIS L S DOUBOYAS J 1997European Journal of Epidemiology1997,,13:1
5Outbreak of infections caused by Pseudomonas aeruginosa producing VIM-1 carbapenemase in Greece 显示文摘Tsakris A Pournaras S Woodford N 2000J Clin Microbiol2000,38,:1
6Novel variant (blaVIM-4) of the metallo--lactamase gene blavIM-1in a clinical strain of Pseudomonas aeruginosa 显示文摘Pournaras S Tsakris A Maniati M 2002Antimicrob Agents Chemother2002,46,:1
7An integron-associated β-lactamase (IBC-2) from Pseudomonas aeruginosa is a variant of the extended-spectrum β-lactamase IBC-1显示文摘Mavroidi A Tzelepi E Tsakris A 2001J Antimicrob Chemother2001,48,:1
8The challenges of antimi- crobial drug resistance in Greece 显示文摘Miyakis S Pefanis A Tsakris A 2011Clin Infect Dis2011,53,2:1
9Outbreak of infections caused by Psendomonas aeruginosa producing VIM-1 carbapenemase in Greece显示文摘Tsakris A Poumaras S Woodfold N 2000J Clin Microbiol2000,38,3:1
10Evaluation of boronic acid disk tests for differentiating KPC-possessing Kleb- siella pneumoniae isolates in the clinical laboratory 显示文摘Tsakris A Kristo I Poulou A 2009J Clin Microbiol2009,47,2:1
11Outbreak of rare serotype of group A streptococcus pharyngitis in a boarding college 显示文摘Tsakris A Pournaras S Hathi D 1999Lancet1999,353,:1
12Efflux System over Expression and Decreased OprD Contribute to the Carbapenem Heterogeneity in Pseudomonas aeruginosa显示文摘Ikonomidis A Tsakris A Kantzanou M 2008FEMS Microbiol Lett2008,279,1:1
13IBC-1, a novel integron-associated class A β-lactamase with extendedspectrum properties produced by an Enterobacter cloacae clinical strain显示文摘Giakkoupi P Tzouvelekis LS Tsakris A 2000Antimicrob Agents Chemother2000,44,:1
14Outbreak of infectious caused by Pseudomonasaeruginosa producing VIM-1 carbapenemasein Greece显示文摘Tsakris A Pournaras S Woodford N 0,,:1
15VIM-I Metallo-β- lactamase in Acinetobacter baumannii显示文摘Tsakris A Ikonomidis A Pournaras S 2006Emerg Infect Dis2006,12,6:1
16IBC-1, a novel int egron-assoc iated class A beta-lactamase with extended-spectrum properties produced by an Enter obacter cloacae clinical strain显示文摘Giakkoupi P Tzouvelekis LS Tsakris A 2000Antimicrob Agents Chemother2000,44,9:1
17VIM-1 Metallo-β-lactamase in Acinetobacter baumannii显示文摘Tsakris A Ikonomidis A Pournaras S 2006Emerg Infect Dis2006,12,6:1
18Evaluation of boronic acid disk tests for differentiating KPC-possessing Klebsiella pneumoniae isolates in the clinical laboratory显示文摘Tsakris A Kristo I Poulou A 2009J Clin Microbiol2009,47,2:1
19Characterization of me- thicillin-resistant Staphylococcus aureus displaying increased MICs of ceftaroline显示文摘Mendes RE Tsakris A Sad er HS 2012J Antimicrob Chemother2012,67,6:1
20A prospective study on bacterial and atypical etiology of acute exacerbation in chronic obstructive pulmonary disease显示文摘Nakou Alexandra Papaparaskevas Joseph Diamantea Filia Skarmoutsou Nikoletta Polychronopoulos Vlasis Tsakris Athanassios 2014Future Microbiology2014,,11:1
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