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| 1 | Lipidomics in non-alcoholic fatty liver disease显示文摘Non-alcoholic fatty liver disease(NAFLD),the most common chronic liver disorder in Western countries,comprises steatosis to nonalcoholic steatohepatitis(NASH),with the latter having the potential to progress to cirrhosis.The transition from isolated steatosis to NASH is still poorly understood,but lipidomics approach revealed that the hepatic lipidome is extensively altered in the setting of steatosis and steatohepatitis and these alterations correlate with disease progression.Recent data suggest that both quantity and quality of the accumulated lipids are involved in pathogenesis of NAFLD.Changes in glycerophospholipid,sphingolipid,and fatty acid composition have been described in both liver biopsies and plasma of patients with NAFLD,implicating that specific lipid species are involved in oxidative stress,inflammation,and cell death.In this article,we summarize the findings of main human lipidomics studies in NAFLD and delineate the currently available information on the pathogenetic role of each lipid class in lipotoxicity and disease progression. | Sofia Kartsoli Christina E Kostara Vasilis Tsimihodimos Eleni T Bairaktari Dimitrios K Christodoulou | 2020 | World Journal of Hepatology2020，12，8： | 5 |
| 2 | 高血压与糖尿病:共同发展与时间轨迹研究显示文摘在人群中2型糖尿病与高血压常合并存在。许多个体糖尿病的发展特点是血浆葡萄糖值的相对快速升高。高血压的发展是否存在相似的现象仍不明确。该研究采用来自墨西哥城糖尿病研究(Mexico city diabetes study,MCDS;一个基于西班牙裔白人的糖尿病人群研究)及Framingham后代研究(Framingham offspring study,FOS;一个基于社区的非西班牙裔白人研究)的7年随访数据,分析未合并或合并糖尿病的患者高血压发展过程中的血压变化模式。 | 赵狄 练桂丽 Tsimihodimos V Gonzalez-Villalpando C Meigs JB Ferrannini E | 2018 | 中华高血压杂志2018，26，1： | 3 |
| 3 | Plasma triglyceride levels and body mass index values are the most important determinants of preβ-1 HDL concentrations in patients with various types of primary dyslipidemia显示文摘 | Vasilis Tsimihodimos Irene Gazi Theodosios Filippatos Michael Kostapanos Kostantinos Lagos Christina Kostara Constantinos C. Tellis Moses Elisaf Alexandros D. Tselepis | 2009 | Atherosclerosis2009，，2： | 2 |
| 4 | Atorvastatin preferentially reduces LDL-associated platelet-activating factor acetyl- hydrolase activity in dyslipidemias of type IIA and type IIB显示文摘 | Tsimihodimos V Karabina SA Tambaki AP | 2002 | Arterioscler Thromb Vasc Biol2002，22，2： | 1 |
| 5 | Dyslipidemia in chronic kidney disease:an approach to pathogenesis and treatment显示文摘 | Tsimihodimos V Dounousi E Siamopoulos KC | 2008 | Am J Nephrol2008，28，6： | 1 |
| 6 | Plasma lipoproteins and triacylglycerol are predictors of small, dense LDL particles 显示文摘 | Tsimihodimos V Gazi I Kostara C | 2007 | Lipids2007，42，5： | 1 |
| 7 | Altera- tion in the high density lipoprotein phenotype and HDL as- sociated enzymes in subjects with metabolic syndrome 显示文摘 | Lagos K G Filippatos T D Tsimihodimos V | 2009 | Lipids2009，44，1： | 1 |
| 8 | Increased plas- ma visfatin concentration is a marker of an atherogenic metabolic profile 显示文摘 | Filippatos T D Tsimihodimos V Derdemezis C S | 2013 | Nutr Metab Cardiovasc Dis2013，23，4： | 1 |
| 9 | High doses of rosuvastatin are superior to low doses of rosuvastatin plus fenofibrate or n-3 fatty acids in mixed dyslipidemia显示文摘 | Agouridis AP Tsimihodimos V Filippatos TD | 2011 | Lipids2011，46，6： | 1 |
| 10 | The effects of rosuvastatin alone or in combination with fenofibrate or omega 3 fatty acids on inflammation and oxidative stress in patients with mixed dyslipidemia显示文摘 | Aris P Agouridis Vasilis Tsimihodimos Theodosios D Filippatos Andromachi A Dimitriou Costantinos C Tellis Moses S Elisaf Dimitri P Mikhailidis Alexandros D Tselepis | 2011 | Expert Opinion on Pharmacotherapy2011，，17： | 1 |
| 11 | Plasma lipoproteins and tri- acylglycerol are predictors of small, dense LDL particles 显示文摘 | Tsimihodimos V Gazi I Kostara C | 2007 | Lipids2007，42，5： | 1 |
| 12 | Fenofibrate induces HDL-associated PAF-AH but attenuates enzyme activity associated with apoB-eontaining lipoproteins 显示文摘 | Tsimihodimos V Kakafika A Tambaki AP | 2003 | J Lipid Res2003，44，5： | 1 |
| 13 | Prediabetes: to treat or not to treat? 显示文摘 | Moutzourl E Tsimihodimos V Rizos E | 2011 | Eur J Pharmaeol2011，672，13： | 1 |
| 14 | Siamopoulos, dys- lipidemia in chronic kidney disease: an approach to pathogenesis and treat- ment显示文摘 | Vasilis Tsimihodimos Evangelia Do- unousi Kostas C | 2008 | Am J Nephrol2008，28，6： | 1 |
| 15 | Increased plasma visfatin concentration is a marker of an atherogenic metabolic profile 显示文摘 | FILIPPATOS TD TSIMIHODIMOS V DERDEMEZIS CS etal | 2013 | Nutr Metab Cardiovasc Dis2013，23，4： | 1 |
| 16 | Plasma lipoproteins and triacylglycerol are predictors of small, dense LDL particle 显示文摘 | Tsimihodimos V Gazi I Kostara C | 2007 | Lipids2007，42，5： | 1 |
| 17 | Small High-Density Lipoprotein (HDL) Subclasses are Increased with Decreased Activity of HDL-Associated Phospholipase A 2 in Subjects with Prediabetes显示文摘 | Theodosios D. Filippatos Evangelos C. Rizos Vasilios Tsimihodimos Irene F. Gazi Alexandros D. Tselepis Moses S. Elisaf | 2013 | Lipids2013，，6： | 1 |
| 18 | Fenofibrate: metabolic and pleiotropic effects 显示文摘 | Tsimihodimos V Miltiadous G Daskalopoulou SS | 2005 | Curr Vasc Pharmacol2005，3，1： | 1 |
| 19 | Plasma lipoproteins and triacylglycerol are predictors of small,dense LDL particle显示文摘 | Tsimihodimos V Gazi I Kostara C | | 0，，： | 1 |
| 20 | Effect of atorvastatin on serum uric acid levels显示文摘 | Kakafika A Tsimihodimos V Elisaf M | 2001 | Atherosclerosis2001，158，1： | 1 |
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