|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | In vivo histological diagnosis for gastric cancer using endocytoscopy显示文摘AIM To examine usefulness of virtual biopsy using endocytoscopy by comparing the in vivo endocytoscopic and histopathological images of gastric cancers.METHODS Endocytoscopy was performed in 30 patients with early gastric cancer. Of these, 26 patients showed well differentiated adenocarcinomas, while 4 patients showed poorly differentiated adenocarcinomas(including one signet ring cell carcinoma). Cancerous and non-cancerous areas were observed after double staining with 0.05% crystal violet and 0.1% methylene blue. The endocytoscopic images obtained were evaluated by an expert endoscopist and an expert pathologist without knowledge of patient clinical data, and endocytoscopic and histopathological diagnoses were compared.RESULTS The endocytoscopic images of the cancerous area were assessed as evaluable in 25(83.3%) and 27(90%) patients by endoscopist A and pathologist B, respectively, and those of the non-cancerous area as evaluable in 28(93.3%) and 23(76.7%) patients by the endoscopist and pathologist, respectively. The sensitivity, specificity, and diagnostic accuracy of gastric cancer diagnosis using evaluable endocytoscopic images were 88.0% and 92.9%, and 90.6% by endoscopist A, and 88.9% and 91.3%, and 90.0% by pathologist B, respectively. Evaluation of the diagnostic concordance rate between the endoscopist and the pathologist by inter-observer agreement calculation revealed no significant difference between the two observers. The inter-observer agreement(κ-value) for endocytoscopic diagnosis was 0.745. CONCLUSION Endocytoscopy is useful for the differentiation of cancerous from non-cancerous gastric mucosa, making it a promising tool for virtual biopsy. | Issei Tsurudome Ryoji Miyahara Kohei Funasaka Kazuhiro Furukawa Masanobu Matsushita Takeshi Yamamura Takuya Ishikawa Eizaburo Ohno Masanao Nakamura Hiroki Kawashima Osamu Watanabe Masato Nakaguro Akira Satou Yoshiki Hirooka Hidemi Goto | 2017 | World Journal of Gastroenterology2017，23，37： | 5 |
| 2 | High resistance of human parainfluenza type 2 virus p cells to the antiviral and anti-cell proliferative activities of alpha/beta interferons: cysteine-rich V-specific domain is required for high resistance to the interferons显示文摘 | Nishio M Tsurudome M Ito M | 2001 | Virology2001，75，： | 1 |
| 3 | Lymphatic Microvessel Density is an Independent Prognostic Factor in Colorectal Cancer显示文摘 | Kentaro Matsumoto M.D. Yoshifumi Nakayama M.D. Ph.D. Yuzuru Inoue M.D. Ph.D. Noritaka Minagawa M.D. Ph.D. Takefumi Katsuki M.D. Kazunori Shibao M.D. Ph.D. Yosuke Tsurudome M.D. Ph.D. Keiji Hirata M.D. Ph.D. Naoki Nagata M.D. Ph.D. Hideaki Itoh M.D. | 2007 | Diseases of the Colon & Rectum2007，，3： | 1 |
| 4 | Identification of domains on the fusion ( F ) protein trimer that influence the hemagglutinin-neuraminidase specificity of the F protein in mediating cell-cell fusion显示文摘 | Tsurudome M Ito M Nishio M | 2011 | Journal of Virology2011，85，7： | 1 |
| 5 | Identifi cation of regions on the hemagglutinin-neuraminidase protein of human parainuenza virus type 2 important for promoting cell fusion显示文摘 | TSURUDOME M KAWANO M YUASA T | 1995 | Virology1995，213，1： | 1 |
| 6 | Neurophysio- logical defects and neuronal gene deregulation in Drosophila mir-124 mutants显示文摘 | Sun K Westholm JO Tsurudome K | 2012 | PLoS Genet2012，8，10： | 1 |
| 7 | Age-associated increase of 8-hydroxydeoxyguanosine in human colotrctal tissue DNA显示文摘 | Tsurudome Y Hirano T Hirata K | 2001 | J Gerontol A Biol Sci Med Sci2001，56，11： | 1 |
| 8 | The drosophila miR-310 cluster negatively regulates synaptic strength at the neuromuscular junction显示文摘 | Tsurudome K Tsang K Liao EH | 2010 | Neuron2010，68，5： | 1 |
| 9 | Neurophysiological defects and neuronal gene deregulation in Drosophila mir 124 mu tants显示文摘 | Sun K Westholm JO Tsurudome K | 2012 | PLoSGenet2012，8，10： | 1 |
| 10 | Existence of leptin receptor protein in chicken tissues; Isolation of a monoclonal antibody against chicken leptin receptor显示文摘 | Ohkubo T Nishio M Tsurudome M Iro M Ito Y | | 0，，： | 1 |
| 11 | Incompressible SPH simulation of solitary wave propagation on permeable beaches显示文摘Wave propagation on uniformly sloped beaches is a canonical coastal engineering topic that has been studied extensively in the past few decades.However,most of these studies treat beaches as solid boundaries even though they are often made of porous materials,such as sediment and vegetation.Permeable beaches struck by tsunami-like waves have not been adequately investigated.It is expected that the degree of penneability plays a crucial role in mitigating the impact of the wave.This study examines solitary wave run-ups on sandy beaches using an incompressible smoothed particle hydrodynamics(ISPH)model.The permeability of the beach is considered to be directly related to the diameter of its constituent sand particles.To obtain a satisfactory pressure field,which cannot be achieved using the original ISPH algorithm,the source term of the pressure Poisson equation has been modified based on a higher-order source-term expression.Flows within the porous medium are computed in the same framework as those outside the porous medium.In the current model,no transition zone is needed at the boundary of the porous structure.The wave-attenuation effect of the porous medium is discussed,with a particular focus on the relationship between the mn-up height and grainsize. | Chiaki Tsurudome Dongfang Liang Yuma Shimizu Abbas Khayyer Hitoshi Gotoh | 2020 | Journal of Hydrodynamics2020，32，4： | 1 |
| 12 | Neurophysi- ological defects and neuronal gene deregulation in Dro- sophila mir-124 mutants显示文摘 | Sun K Westholm J O Tsurudome K | 2012 | PLoS Genet2012，8，10： | 1 |
| 13 | Lymphatic Microvessel Density is an Independent Prognostic Factor in Colorectal Cancer显示文摘 | Kentaro Matsumoto M.D. Yoshifumi Nakayama M.D. Ph.D. Yuzuru Inoue M.D. Ph.D. Noritaka Minagawa M.D. Ph.D. Takefumi Katsuki M.D. Kazunori Shibao M.D. Ph.D. Yosuke Tsurudome M.D. Ph.D. Keiji Hirata M.D. Ph.D. Naoki Nagata M.D. Ph.D. Hideaki Itoh M.D. | 2007 | Diseases of the Colon & Rectum2007，，3： | 1 |
| 14 | Lipid interactions of the hemagglutinin HA2 NH2-terminal segment during influenza virus-induced membrance fusion显示文摘 | Tsurudome M Gluck R Graf R | 1992 | J Biol Chem1992，267，20： | 1 |
| 15 | Recombinant Sendai viruses with L1618V mutation in their L polymerase protein establish persistent infection,but not temperature sensitivity 显示文摘 | Nishio M Nagata A Tsurudome M | 2004 | Virology2004，329，2： | 1 |
| 16 | Extensive antigenic diversity among human parainfluenza type 2 virus isolates and immunological relationships among paramyxoviruses revealed by monoclonal antibodies显示文摘 | Tsurudome M Nishio M Komada H | 1989 | Virology1989，171，： | 1 |
| 17 | Enhancement of human parainfluenza virus-induced cell fusion by pradimicin, a low molecular weight mannose-binding antibiotic显示文摘 | Kousuke Okamoto Toshikazu Oki Yasuhiro Igarashi Masato Tsurudome Machiko Nishio Mitsuo Kawano Hiroshi Komada Morihiro Ito Yasuo Sakakura Y. Ito | 1997 | Medical Microbiology and Immunology (-)1997，，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员