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    题名 作者 年代 出处 被引量
1Report of an international workshop to standardize baseline evaluation and response criteria for primary CNS lymphoma.显示文摘Abrey LE Batchelor TT Ferreri A J Gospodarowicz M Pulczynski EJ Zucca E Smith JR Korfel A Soussain C DeAngelis LM Neuwelt EA O′Neill BP Thiel E Shenkier T Graus F van den Bent M Seymour JF Poortmans P Armitage JO Cavalli F 2005中国神经肿瘤杂志2005,3,3:53
2糖尿病膀胱的尿动力学及病理学改变(附动物实验与临床观察)显示文摘目的:观察糖尿病膀胱(DCP)的尿动力学及病理学改变,探讨发病机制及病理演绎过程。方法:建立DCP wistar大鼠模型(30只),正常wistar大鼠作对照(30只),进行膀胱储尿期压、最大容量、最大膀胱压等测定,进行膀胱湿重、膀胱壁厚度及光镜、电镜的病理学观察。早期DCP患者(32例),晚期DCP(28例)及非DM人群(22例)进行尿流率、压力-流率尿道分布压及括约肌肌电图等测定,作相关统计学处理。结果:①60天后,DCP鼠组与对照组:膀胱储尿期压(0.45±0.08)kPa,(0.60±0.03)kPa(P<0.05);最大膀胱容量(3.49±0.40)ml,(1.82±0.12)ml(P<0.01);最大膀胱压(3.09±0.10)kPa,(4.91±0.30)kPa(P<0.01);膀胱顺应性(1.39±0.11)ml.kPa-1,(0.68±0.07)ml.kPa-1(P<0.01);湿重增加(P<0.01);逼尿肌细胞连接纤维化,成纤维细胞变性及胶原纤维排列紊乱。②相对于对照组,早期DCP患者最大尿流率偏低,为(15.97±5.71)ml.s-1(P<0.05),逼尿肌活动亢进(占59%),逼尿肌/括约肌协同失调(占37.5%);而晚期DCP患者最大尿流率明显下降,为(8.75±4.20)ml.s-1(P<0.01),膀胱容量增加,为(472.5±32.9)ml(P<0.01),剩余尿量增多,为(62.59±19.87)ml(P<0.01),逼尿肌收缩功能减弱。结论:DCP早期就有膀胱的动力学及病理学改变,以逼尿肌活动功能亢进,逼尿肌/括约肌协同失调较常见,晚期以逼尿肌收缩功能减弱为主,建议对DCP患者早期就应给予干预,控制病情的进一步恶化。卫中庆 van Koeveringe G A 田成功 王昱 于洪波 易超然 孙则禹 陈炜 van Kerrebroeck P E 2005临床泌尿外科杂志2005,20,11:11
3High-density SNP-based genetic maps for the parents of an outcrossed and a selfed tetraploid garden rose cross, inferred from admixed progeny using the 68k rose SNP array显示文摘Dense genetic maps create a base for QTL analysis of important traits and future implementation of marker-assisted breeding.In tetraploid rose,the existing linkage maps include<300 markers to cover 28 linkage groups(4 homologous sets of 7 chromosomes).Here we used the 68k WagRhSNP Axiom single-nucleotide polymorphism(SNP)array for rose,in combination with SNP dosage calling at the tetraploid level,to genotype offspring from the garden rose cultivar‘Red New Dawn’.The offspring proved to be not from a single bi-parental cross.In rose breeding,crosses with unintended parents occur regularly.We developed a strategy to separate progeny into putative populations,even while one of the parents was unknown,using principle component analysis on pairwise genetic distances based on sets of selected SNP markers that were homozygous,and therefore uninformative for one parent.One of the inferred populations was consistent with self-fertilization of‘Red New Dawn’.Subsequently,linkage maps were generated for a bi-parental and a self-pollinated population with‘Red New Dawn’as the common maternal parent.The densest map,for the selfed parent,had 1929 SNP markers on 25 linkage groups,covering 1765.5 cM at an average marker distance of 0.9 cM.Synteny with the strawberry(Fragaria vesca)genome was extensive.Rose ICM1 corresponded to F.vesca pseudochromosome 7(Fv7),ICM4 to Fv4,ICM5 to Fv3,ICM6 to Fv2 and ICM7 to Fv5.Rose ICM2 corresponded to parts of F.vesca pseudochromosomes 1 and 6,whereas ICM3 is syntenic to the remainder of Fv6.Mirjana Vukosavljev Paul Arens Roeland E Voorrips Wendy P C van't Westende G D Esselink Peter M Bourke Peter Cox W Eric van de Weg Richard G F Visser Chris Maliepaard Marinus J M Smulders 2016Horticulture Research2016,3,1:6
4Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density显示文摘W.S Simonet D.L Lacey C.R Dunstan M Kelley M.-S Chang R Lüthy H.Q Nguyen S Wooden L Bennett T Boone G Shimamoto M DeRose R Elliott A Colombero H.-L Tan G Trail J Sullivan E Davy N Bucay L Renshaw-Gegg T.M Hughes D Hill W Pattison P Campbell S Sander G Van 1997Cell1997,,2:6
5Colonoscopic yield of colorectal neoplasia in daily clinical practice显示文摘AIM:To assess the prevalence and location of ad-vanced neoplasia in patients undergoing colonoscopy,and to compare the yield per indication.METHODS:In a multicenter colonoscopy survey (n = 18 hospitals) in the Amsterdam area (Northern Holland),data of all colonoscopies performed during a three month period in 2005 were analyzed. The location and the histological features of all colonic neoplasia were recorded. The prevalence and the distribution ofadvanced colorectal neoplasia and differences in yield between indication clusters were evaluated. Advanced neoplasm was defi ned as adenoma > 10 mm in size,with > 25% villous features or with high-grade dyspla-sia or cancer.RESULTS:A total of 4623 eligible patients underwent a total colonoscopy. The prevalence of advanced neo-plasia was 13%,with 281 (6%) adenocarcinomas and 342 (7%) advanced adenomas. Sixty-seven percent and 33% of advanced neoplasia were located in the distal and proximal colon,respectively. Of all patients with right-sided advanced neoplasia (n = 228),51% had a normal distal colon,whereas 27% had a syn-chronous distal adenoma. Ten percent of all colono-scopies were performed in asymptomatic patients,7% of whom had advanced neoplasia. In the respective procedure indication clusters,the prevalence of right-sided advanced neoplasia ranged from 11%-57%. CONCLUSION:One out of every 7-8 colonoscopies yielded an advanced colorectal neoplasm. Colonoscopy is warranted for the evaluation of both symptomatic and asymptomatic patients.Jochim S Terhaar sive Droste Mike E Craanen Rene WM van der Hulst Joep F Bartelsman Dick P Bezemer Kim R Cappendijk Gerrit A Meijer Linde M Morsink Pleun Snel Hans ARE Tuynman Roy LJ van Wanrooy Eric IC Wesdorp Chris JJ Mulder 2009World Journal of Gastroenterology2009,15,9:6
6Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial显示文摘Roger Stupp Monika E Hegi Warren P Mason Martin J van den Bent Martin JB Taphoorn Robert C Janzer Samuel K Ludwin Anouk Allgeier Barbara Fisher Karl Belanger Peter Hau Alba A Brandes Johanna Gijtenbeek Christine Marosi Charles J Vecht Karima Mokhtari Piet 2009Lancet Oncology2009,,5:4
7Frequent amplification of a chr19q13.41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors显示文摘Li M Lee KF Lu Y Clarke I Shih D Eberhart C Collins VP Van Meter T Picard D Zhou L Boutros PC Modena P Liang ML Scherer SW Bouffet E Rutka JT Pomeroy SL Lau CC Taylor MD Gajjar A Dirks PB Hawkins CE Huang A. 2009中国神经肿瘤杂志2009,7,4:3
8Medical image matching-a review with classification 显示文摘VAN DEN ELSEN P A POL E J D VIERGEVER M A 1993IEEE Eng in Med & Biol1993,12,1:2
9Geometric ergodicity and quasi-stationarity in discrtet-time birth-death processes显示文摘Van Doorn E A Schrijner P 1995J Austral Math Soc: Ser B1995,37,:2
10男、女尿失禁手术治疗进展显示文摘随着对尿失禁机制研究的深入,引发一系列新的尿失禁手术方法。本文介绍了有关手术的概述、要点、适应证、并发症的处理及疗效,对每种手术的特点加以评述:①经阴道前壁韧带筋膜吊带术中的同种异体筋膜方法远期疗效更好;②经尿道无张力尿道中段吊带术(TVT)对尿道解剖结构异常及内源性尿道缺损引起的女性压力性尿失禁都有效,是目前应用较广的术式;③经闭孔尿道中段吊带术与TVT疗效相同,可减少手术操作时间和膀胱损伤;④经阴道尿道耻骨悬吊术结合了传统的尿道悬吊术和吊带术,远期复发率低;⑤内腔镜下注射胶原体,简便、安全,可多次治疗;⑥射频治疗尿失禁是一种新疗法,无需外来材料,远期疗效有待观察;⑦骶神经调控术对难治性急迫性尿失禁不失为一种有效的方法;⑧人工尿道括约肌术给严重的尿失禁带来希望;⑨尿道球部/阴茎海绵体间置术,对前列腺术后尿失禁完全性尿失禁可采用。卫中庆 宋涛 van Kerrebroeck P E V 2006临床泌尿外科杂志2006,21,2:2
11Job shop scheduling by simulated annealing显示文摘LAARHOVEN Van P AARTS E LENSTRA J K 1992Operations Research1992,40,1:1
12Erythropoietin in cardiovascular diseases 显示文摘Van der Meera P Voors AA Lipsie E 2004Europ Heart J2004,25,:1
13EGFR expression predicts BRCA1 status in patients with breast eancer显示文摘van Diest PJ van der Groep P van der Wall E 2006Clin Cancer Res2006,12,2:1
14Interstitial radiation therapy for early-slagenasal vestibule cancer: A continuing quest for optimal tumor control and cosmesis显示文摘Levendag P C Nijdam W M van Moolenburgh S E 2006Int Radiat Oncol Biol Phys2006,66,1:1
15The relation between morphology and hydrotreating activity for supported MoS2 particles 显示文摘HENSEN E J M KOOYMAN P J Van der MEER Y Van der KRAAN A M de BEER V H J Van VEEN J A R Van SANTEN R A 2001J Catal2001,199,2:1
16Fractionation of sulfur and oxygen isotopes in sulfate by soil sorption 显示文摘van Stempvoort D R Reardon E J Fritz P 1990Geochim Cosmochim Acta1990,54,10:1
17Organic carbon in soils of the world显示文摘ESWARRAN H E VAN DEN BERG E V REICH P 1993Soil Science Society of America Journal1993,57,:1
18Patient adherence to treatment: Three decades of research (A comprehensive review) 显示文摘Vermeire E Heamshaw H Van Royen P 2001J Clini Pharm Ther2001,26,5:1
19Hierarchical crosstraining in work-in-process-constrained systems 显示文摘Gel E S Hopp W J Van Oyen M P 2007lie Transactions2007,39,2:1
20Transvaginal ovum pick-up(OPU)in the cow:A new disposable needle guidance system显示文摘Bols P E J Vandenheede J M M Van Soom A 1995Theriogenology1995,43,:1
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