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4篇 您的检索式:作者名="Vasant Sumethkul"
    题名 作者 年代 出处 被引量
1Survival Advantage of Kidney Transplantation Over Dialysis in Patients With Hepatitis C: A Systematic Review and Meta-Analysis显示文摘Atiporn Ingsathit Nanticha Kamanamool Ammarin Thakkinstian Vasant Sumethkul 2013Transplantation Journal2013,,7:1
2Lupus nephritis and Raynaud’s phenomenon are significant risk factors for vascular thrombosis in SLE patients with positive antiphospholipid antibodies显示文摘Kittiwan Choojitarom Orawan Verasertniyom Kitti Totemchokchyakarn Kanokrat Nantiruj Vasant Sumethkul Suchela Janwityanujit 2008Clinical Rheumatology2008,,3:1
3Kidney transplant from donors with hepatitis B: A challenging treatment option显示文摘Utilizing kidneys from donors with hepatitis B is one way to alleviate the current organ shortage situation.However,the risk of hepatitis B virus(HBV)transmission remains a challenge that undermines the chance of organs being used.This is particularly true with hepatitis B surface antigen(HBsAg)positive donors despite the comparable long-term outcomes when compared with standard donors.To reduce the risk of HBV transmission,a comprehensive approach is needed.This includes assessment of donor risk,optimal allocation to the proper recipient,appropriate immunosuppressive regimen,optimizing the prophylactic therapy,and post-transplant monitoring.This review provides an overview of current evidence of kidney transplants from donors with HBsAg positivity and outlines the challenge of this treatment.The topics include donor risk assessment by adopting the nucleic acid test coupled with HBV DNA as the HBV screening,optimal recipient selection,importance of hepatitis B immunity,role of nucleos(t)ide analogues,and hepatitis B immunoglobulin.A summary of reported long-term outcomes after kidney transplantation and proposed criteria to utilize kidneys from this group of donors was also defined and discussed.Praopilad Srisuwarn Vasant Sumethkul 2021World Journal of Hepatology2021,13,8:1
4Stabilization of estimated glomerular filtration rate in kidney transplantation from deceased donors with acute kidney injuries显示文摘AIM To evaluate and compare the outcomes of kidney transplant(KT) from deceased donors among standard criteria, acute kidney injury(AKI) and expanded criteria donors(ECDs). METHODS This retrospective study included 111 deceased donor kidney transplant recipients(DDKT). Deceased donors were classified as standard criteria donor(SCD), AKI donor and ECD. AKI was diagnosed and classified based on change of serum Cr by acute kidney injury network(AKIN) criteria. Primary outcome was one-year estimated glomerular filtration rate(eG FR) calculated from Cr by CKD-EPI. Multivariate regression analysis was done by adjusting factors such as type of DDKT, %Panel-reactive antibodies, cold ischemic time, the presence of delayed graft function and the use of induction therapy. Significantfactors that can affect the primary outcomes were then identified. RESULTS ECD group had a significantly lower eG FR at one year(33.9 ± 17.3 mL /min) when compared with AKI group(56.6 ± 23.9) and SCD group(63.6 ± 19.9)(P < 0.001). For AKI group, one-year eG FR was also indifferent among AKIN stage 1, 2 or 3. Patients with AKIN stage 3 had progressive increase of eG FR from 49.6 ± 27.2 at discharge to 61.9 ± 29.0 mL /min at one year. From Kaplan-Meier analysis, AKI donor showed better two-year graft survival than ECD(100% vs 88.5%, P = 0.006). Interestingly, AKI group had a stable eG FR at one and two year. The two-year eG FR of AKI group was not significantly different from SCD group(56.6 ± 24.5 mL /min vs 58.6 ± 23.2 mL /min, P = 0.65). CONCLUSION Kidney transplantations from deceased donors with variable stage of acute kidney injuries were associated with favorable two-year allograft function. The outcomes were comparable with KT from SCD. This information supports the option that deceased donors with AKI are an important source of organ for kidney transplantation even in the presence of stage 3 AKI.Punlop Wiwattanathum Atiporn Ingsathit Surasak Kantachuvesiri Nuttapon Arpornsujaritkun Wiwat Tirapanich Vasant Sumethkul 2016World Journal of Transplantation2016,6,4:0
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